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The map label for this gene is gst [H]

Identifier: 148359545

GI number: 148359545

Start: 2326798

End: 2327421

Strand: Reverse

Name: gst [H]

Synonym: LPC_1457

Alternate gene names: 148359545

Gene position: 2327421-2326798 (Counterclockwise)

Preceding gene: 148359546

Following gene: 148359540

Centisome position: 65.08

GC content: 39.9

Gene sequence:

>624_bases
ATGTATACACTTTATTCATTCGGGACGCCCAACGGATTTAAGCCCACTATTATGTTGGAAGAGTTGGCGCAGCCTTATAC
CATAAAACTGATTGATATTACTCAGGGTGAACAATTTAATCCTGATTTTTTAAAAATTTCACCAAACAATAAGATACCTG
TTTTGCATGATCAAACCAATGATTTTTACCTAATGGAAAGCGTTGCTATTTTGCAATATTTGGCTGAAAAACATAGACAG
TTTTTGCCTGAAACGACAAAGGAGAAATATGCCATTATCCAATGGTGTTATTTCCAGGCAGCACACATAGGCCCTATGTT
AGGGCAATTTGGTCATTTTCATCGTTATGCTCAAGAGCAAGTACCCTATGCCATGAAGCGATATGCTGATGAATCCATGC
GACTTCTAGGGGTCATGGAAAAGCAACTGGCCAAAACGTCATTCATTGGCGGATCAAATTATACTATTGCTGATATGGCT
ATCTGGCCCTGGATTTGGTGTTTTCAATTCATATATGGACAGACTATTGATGCGAAACTGTTTCCCAGTTTAATGTCCTG
GTATCAACGAGTTAGTGAAAGGCCTGCTCTTAAAGCGACTCTAGCCGCCTATGGGCGACTATGA

Upstream 100 bases:

>100_bases
GTTTGTCCTTATTCCAATGCAATACGTGGTAATGTTGAAGTGAAATTGAGTGTTAGTGTCAAGTGATAGATAACTTCCAT
CAATCAATAAGGATATCTTA

Downstream 100 bases:

>100_bases
TTATTGGAACCTATCGGATAATTAATTGCTCCCAATTGCCGCAATGGTGCCAATTGGGGTGCTTTACCTGGTTATTGCTT
CAATAGATTATGTCATCTTG

Product: glutathione S-transferase

Products: NA

Alternate protein names: GST-like protein yfcG [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MYTLYSFGTPNGFKPTIMLEELAQPYTIKLIDITQGEQFNPDFLKISPNNKIPVLHDQTNDFYLMESVAILQYLAEKHRQ
FLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQVPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMA
IWPWIWCFQFIYGQTIDAKLFPSLMSWYQRVSERPALKATLAAYGRL

Sequences:

>Translated_207_residues
MYTLYSFGTPNGFKPTIMLEELAQPYTIKLIDITQGEQFNPDFLKISPNNKIPVLHDQTNDFYLMESVAILQYLAEKHRQ
FLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQVPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMA
IWPWIWCFQFIYGQTIDAKLFPSLMSWYQRVSERPALKATLAAYGRL
>Mature_207_residues
MYTLYSFGTPNGFKPTIMLEELAQPYTIKLIDITQGEQFNPDFLKISPNNKIPVLHDQTNDFYLMESVAILQYLAEKHRQ
FLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQVPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMA
IWPWIWCFQFIYGQTIDAKLFPSLMSWYQRVSERPALKATLAAYGRL

Specific function: Has disulfide bond reductase activity (in vitro). Has low hydroperoxidase activity with cumene hydroperoxide. Has very low glutathione-S-transferase activity (in vitro) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GST N-terminal domain [H]

Homologues:

Organism=Escherichia coli, GI1788640, Length=206, Percent_Identity=43.2038834951456, Blast_Score=176, Evalue=1e-45,
Organism=Escherichia coli, GI87082195, Length=207, Percent_Identity=41.5458937198068, Blast_Score=157, Evalue=5e-40,
Organism=Escherichia coli, GI87081789, Length=184, Percent_Identity=29.3478260869565, Blast_Score=76, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324100, Length=241, Percent_Identity=29.4605809128631, Blast_Score=99, Evalue=4e-22,
Organism=Drosophila melanogaster, GI28571670, Length=185, Percent_Identity=31.3513513513514, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010987
- InterPro:   IPR004045
- InterPro:   IPR017933
- InterPro:   IPR004046
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00043 GST_C; PF02798 GST_N [H]

EC number: NA

Molecular weight: Translated: 24138; Mature: 24138

Theoretical pI: Translated: 8.17; Mature: 8.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTLYSFGTPNGFKPTIMLEELAQPYTIKLIDITQGEQFNPDFLKISPNNKIPVLHDQTN
CEEEEECCCCCCCCCCEEHHHHCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
DFYLMESVAILQYLAEKHRQFLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMAIWPWIWCFQFIYGQTIDAKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCHHH
FPSLMSWYQRVSERPALKATLAAYGRL
HHHHHHHHHHHHCCCHHHHHHHHHCCC
>Mature Secondary Structure
MYTLYSFGTPNGFKPTIMLEELAQPYTIKLIDITQGEQFNPDFLKISPNNKIPVLHDQTN
CEEEEECCCCCCCCCCEEHHHHCCCEEEEEEEECCCCCCCCCEEEECCCCCCCEEECCCC
DFYLMESVAILQYLAEKHRQFLPETTKEKYAIIQWCYFQAAHIGPMLGQFGHFHRYAQEQ
CCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPYAMKRYADESMRLLGVMEKQLAKTSFIGGSNYTIADMAIWPWIWCFQFIYGQTIDAKL
CCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHHHHHHHCCCCCHHH
FPSLMSWYQRVSERPALKATLAAYGRL
HHHHHHHHHHHHCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]