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The map label for this gene is yfhC [H]

Identifier: 148359260

GI number: 148359260

Start: 1994322

End: 1994765

Strand: Reverse

Name: yfhC [H]

Synonym: LPC_1155

Alternate gene names: 148359260

Gene position: 1994765-1994322 (Counterclockwise)

Preceding gene: 148359261

Following gene: 148359257

Centisome position: 55.77

GC content: 40.77

Gene sequence:

>444_bases
ATGATTGATAAATTTTGGATGCAACTGGCTTACGAGCAAGCGGTTATAGCTCGTAATGAAGGAGAGGTTCCTGTTGGGGC
TGTGTTGGTTAGCAAAGACAATCAATTATTAGGCGTTGGCAGAAATGTCATTGAAAAAAGTCATGATCCTTCTGATCATG
CTGAAATCAGGGCAATACGACAAGCCTCGAGAAAATTAAATAATCATAGATTATTGGATACAACGCTTTATGTTACTCTT
GAACCCTGTGTGATGTGTGCGGGACTTATGGTTCACGCACGCATCAAACGGCTGGTATTTGCTACCCGAGATTTTAAAGC
AGGGGCAGCTGGCTCAATGTTTAATGTTTTACATGCTCTAAACCATTCGGTATTAATAGACGAAGGAATTATGCAGGCTG
AGTGTTCTCAATTGCTATCAGATTTTTTCAGAAACCTTCGCTAG

Upstream 100 bases:

>100_bases
TTTTAGGAAAAGTATCCAATCGAATTATTAATGAAGTAGAGGGAGTATCACGTGTCACTTACGATATTTCTGGCAAGCCA
CCTGCTACCATTGAATGGGA

Downstream 100 bases:

>100_bases
TAATTTATCTTGGCATATTTCTTAATATTTGCTTTTAGAAATTTCCAAAATTAATTTTTCTTTTAAAATTGTTTTTTCCT
CATGATTCAGGGAATAACCT

Product: deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVTL
EPCVMCAGLMVHARIKRLVFATRDFKAGAAGSMFNVLHALNHSVLIDEGIMQAECSQLLSDFFRNLR

Sequences:

>Translated_147_residues
MIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVTL
EPCVMCAGLMVHARIKRLVFATRDFKAGAAGSMFNVLHALNHSVLIDEGIMQAECSQLLSDFFRNLR
>Mature_147_residues
MIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIRQASRKLNNHRLLDTTLYVTL
EPCVMCAGLMVHARIKRLVFATRDFKAGAAGSMFNVLHALNHSVLIDEGIMQAECSQLLSDFFRNLR

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=149, Percent_Identity=30.8724832214765, Blast_Score=75, Evalue=3e-14,
Organism=Escherichia coli, GI145693172, Length=146, Percent_Identity=56.1643835616438, Blast_Score=160, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=31.0810810810811, Blast_Score=77, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17554608, Length=97, Percent_Identity=35.0515463917526, Blast_Score=70, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6325319, Length=143, Percent_Identity=32.1678321678322, Blast_Score=74, Evalue=8e-15,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=30.1369863013699, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16488; Mature: 16488

Theoretical pI: Translated: 8.11; Mature: 8.11

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHCCCCCCHHHHHHHHH
QASRKLNNHRLLDTTLYVTLEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSMFNVLHAL
HHHHHHCCCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NHSVLIDEGIMQAECSQLLSDFFRNLR
CCCHHHHCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIDKFWMQLAYEQAVIARNEGEVPVGAVLVSKDNQLLGVGRNVIEKSHDPSDHAEIRAIR
CCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCEECCCHHHHHCCCCCCHHHHHHHHH
QASRKLNNHRLLDTTLYVTLEPCVMCAGLMVHARIKRLVFATRDFKAGAAGSMFNVLHAL
HHHHHHCCCEEEHEEEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHH
NHSVLIDEGIMQAECSQLLSDFFRNLR
CCCHHHHCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]