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The map label for this gene is putA [H]

Identifier: 148359231

GI number: 148359231

Start: 1958525

End: 1961677

Strand: Reverse

Name: putA [H]

Synonym: LPC_1125

Alternate gene names: 148359231

Gene position: 1961677-1958525 (Counterclockwise)

Preceding gene: 148359234

Following gene: 148359230

Centisome position: 54.85

GC content: 40.79

Gene sequence:

>3153_bases
ATGCTGGAAAAGCAGTCCATTCATTTACCGGAAGGATTAAGAGCTGCTATTAATAAAGCTTATCGCATGGATGAGCTTTC
TTTAATTACAGAGCTTAGTGAACAGGCAGCACTTGATCCTCAGCAAATGATGGCAATTAAAACCAGTGCTACAAAATTGG
TTCAATCAGTTCGTAGTGAGAGAAAGAAAAGCACAGGAATAGATTCTTTTTTAACGGAGTATGCCTTATCAAGTGATGAG
GGAATTGCCTTAATGTGTCTGGCAGAAGCTTTATTACGCGTTCCTGATAATGCCACCATAGATAACTTGATTAAAGATAA
ATTAGCTGGCGGTGATTGGGGGGCGCATCGTGGACAGAGTGAATCATTTTTTGTAAATGCTACTACTTGGGCTTTAATGC
TAACTGGTAAAGTTTTAACTCCTGAAAAAGCTGAAAATACATTAACCAAAGCTTTACTAAAATTGGTTAATCGAAGTAGT
GAGGCTGTTGTTAGAAAAGCAGTGGATAAAGCCATGCGAATTATGAGCAAACAATTTGTGATGGGACGTACCATTAATGA
AGCGTTAGCTCGAGCGAAAAAAAAGGAAGACAGGGGATACAGATATTCTTACGATATGCTTGGTGAAGCTGCCTTAACAT
CTGCTGATGCTGCAAGATATTTTGAAGCCTACAAGGAAGCAATCATTTCAATTGGAGAGAAAGCTGATAAACATTCAGAT
GTATATAGACGCCCTGGTATTTCCATCAAACTTTCTGCCTTACATCCACGATATAGCGAGTTTCAGTATGAGCGTGTCAT
GGCAGAATTACCCCCCAAATTATTAGCCTTGTCTCGTTTAGCAAAAGATTATGGTATTGCTTTGACAATTGACGCCGAGG
AGTCAGAGCGTTTAGATCTTTCGCTTGATGTGATAGAGAAAGTGTTTACTGATGAGAGTTTACAGGGATGGAATGGGTTC
GGTTTGGCCGTTCAATCCTATCAAAAAAGAGCTTTTTATGTCTTGGATTGGGTTGCTGCTTTAGCAAGAAGTAAGCAGCG
GCGTATTATGGTCAGATTGATTAAAGGAGCCTATTGGGATAGTGAAATCAAAAAAACGCAAATGCAAGGCTTTTCTGAAT
ACCCGGTTTTTACCCGTAAAGTATTTACTGACGTGTCATTTCAGGCTTGTGCAAAAAAAATCCTGACTATGACCGATGCC
ATTTATCCACAATTTGCCACACATAATGCTTATTCTGTAGCAATGATTCTTAATTTGGTAGGAGGTTATAGAGATTTTGA
ATTTCAATGTCTGCATGGTATGGGTAATGAACTTTATGAACAGATTGTTCCAGCAAATTGTTATGGTATTCCATGCCGTA
TTTATGCACCAGTTGGTAGCCATGAGGATTTATTACCGTATTTAGTTCGACGATTACTGGAAAATGGAGCAAACTCATCT
TTTGTCAATCGCATAGTTGATGATAAGGCACCTATTAGCGAGTTAGTGGAGGACCCGGTAGCTAAATCAAGATCGTTACT
TGATAAAATAAATAAAAATATACCATTGCCAGAGGATATCTTTTTACCCGTACGAAAAAATTCTAAAGGCTTTGACTTTA
CAAATCGACTTGAACGCGCATTATTGCAGCAGGAACTGGCAAAAATTGAATCAAAAGAATGGCAGGCAAGTCCTATGATT
GCTGGTCGAAAATTATCCAGGGACTTACTGCAAACAGTTATGTCCCCACAGCAGCCGGCATATGCTATTGGCTCAGTGCA
GCAAGCCACACTTGATGATGTAGAGGTGGCATTAAATCAGGCAAAATTGGCTTTTGAATTGTGGAGCAAGAAACCAGTAG
AAGAACGCGCTTCTTGTCTAAATCGATTTGCAGATTTATTACAGGCCAATATGGCAGAGCTCATGGTATTGACTTGTCGG
GAAGCTGGTAAAACCTGGAGTGATGGCATTGCTGAAGTAAGAGAGGCTATTGATTTTTGTCGATACTATGCCAAGAAAGC
TCAAGAGCTTATGAGTAGCCCTCAACGCTTTAATGGATACACTGGGGAACTAAATGAATTGAGTTTGCATCCTCGCGGGA
CAATATTGTGTATTAGTCCCTGGAATTTTCCATTGGCTATATTTACGGGACAAGTCGTAGCCGGGCTGGTTACAGGCAAT
TGTGTTATTGCGAAACCGGCAGAACAAACGCCACTAATTGCAGCCTATGCTGTGAAGTTAATGCATCAGGCCGGTATCCC
TGAAGGAGTAATTCAATTAATTCCAGGCGCTGGAGAGACTATTGGCGCTGCTTTGGTCGCAGATAAACGAATTAAAGCAG
TATTATTTACAGGCTCGACTGACACGGCGAATTTGATTAATCGGACGCTAGCTACTCGAGGTGGTGAAATCATTCCTCTA
ATTGCTGAAACAGGTGGTCAAAATGCAATGATTGTCGATTCTTCAGCATTATTGGAACAAGTGGTTGTTGATGCTGTCAC
TTCTGCCTTTGGCAGCGCGGGGCAGCGATGCTCGGCACTTAGGGTATTGTATGTGCAAGAGGAAGTGTATCCAAGAACTG
TAGAGCTATTAAAAGGTGCCATGGCTGAGCTAGTCGTAGGGGATCCTCAATGGTTATCAACCGATGTTGGCCCTGTTATA
GACAAGGAAGCATTATCTATATTGAAAAATCATGTCGAAAACATGAGAAAACATCATGAAATATTATATCAATGCACTGT
TGACGATGAAGCTTTATCAGGATATTTCATGCCGCCAACAGCTATTGCAATTGATAGTATCAGCGCTTTGGAAAAAGAAG
TATTTGGGCCAATTTTGCATGTGATTCAGTTTAAGAGAAAAGATCTGGATAAGGTAATTAATCAAATCAATCAAACTAGC
TATGGTTTAACACTGGGAATACACAGCCGAATTAATGAAACAGTTGACTACATTAGGCAAAGGGTTCATGCAGGGAACTG
TTATGTAAATCGTAATATGATTGGCGCAGTAGTAGGTCTACAGCCTTTTGGTGGTGAAGGGTTATCTGGCACAGGACCCA
AGGCTGGAGGCCCTAACTATTTGATTCGACTTTGCCATGAGCGTACCTATACAGTTGATACAACTGCTGCAGGAGGCAAT
GCCAGTTTAATGTCTATCCCGGAAGAAGGTTAG

Upstream 100 bases:

>100_bases
GATTTTTTCATTGTTATAATAATGAATTTAATTTTTGTCTTATATGGTAAAAATTTAATAACTATTTTTTTCAATTACCA
CTTTAGTCTTGGAGAACATT

Downstream 100 bases:

>100_bases
CAGTATTAGAAATTCACTTAAGAGAATAATAAAATCTTAAGTGAATTTATTACAGGAGATCTGCCCCTGTCTGGAACGGC
AATATTTGGTTGTTCTTGTA

Product: bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase

Products: NA

Alternate protein names: Proline dehydrogenase; Proline oxidase; Delta-1-pyrroline-5-carboxylate dehydrogenase; P5C dehydrogenase [H]

Number of amino acids: Translated: 1050; Mature: 1050

Protein sequence:

>1050_residues
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSERKKSTGIDSFLTEYALSSDE
GIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQSESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSS
EAVVRKAVDKAMRIMSKQFVMGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
VYRRPGISIKLSALHPRYSEFQYERVMAELPPKLLALSRLAKDYGIALTIDAEESERLDLSLDVIEKVFTDESLQGWNGF
GLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWDSEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDA
IYPQFATHNAYSVAMILNLVGGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
FVNRIVDDKAPISELVEDPVAKSRSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERALLQQELAKIESKEWQASPMI
AGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQAKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCR
EAGKTWSDGIAEVREAIDFCRYYAKKAQELMSSPQRFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGSTDTANLINRTLATRGGEIIPL
IAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSALRVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVI
DKEALSILKNHVENMRKHHEILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTS
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNYLIRLCHERTYTVDTTAAGGN
ASLMSIPEEG

Sequences:

>Translated_1050_residues
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSERKKSTGIDSFLTEYALSSDE
GIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQSESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSS
EAVVRKAVDKAMRIMSKQFVMGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
VYRRPGISIKLSALHPRYSEFQYERVMAELPPKLLALSRLAKDYGIALTIDAEESERLDLSLDVIEKVFTDESLQGWNGF
GLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWDSEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDA
IYPQFATHNAYSVAMILNLVGGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
FVNRIVDDKAPISELVEDPVAKSRSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERALLQQELAKIESKEWQASPMI
AGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQAKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCR
EAGKTWSDGIAEVREAIDFCRYYAKKAQELMSSPQRFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGSTDTANLINRTLATRGGEIIPL
IAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSALRVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVI
DKEALSILKNHVENMRKHHEILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTS
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNYLIRLCHERTYTVDTTAAGGN
ASLMSIPEEG
>Mature_1050_residues
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSERKKSTGIDSFLTEYALSSDE
GIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQSESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSS
EAVVRKAVDKAMRIMSKQFVMGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
VYRRPGISIKLSALHPRYSEFQYERVMAELPPKLLALSRLAKDYGIALTIDAEESERLDLSLDVIEKVFTDESLQGWNGF
GLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWDSEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDA
IYPQFATHNAYSVAMILNLVGGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
FVNRIVDDKAPISELVEDPVAKSRSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERALLQQELAKIESKEWQASPMI
AGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQAKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCR
EAGKTWSDGIAEVREAIDFCRYYAKKAQELMSSPQRFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGSTDTANLINRTLATRGGEIIPL
IAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSALRVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVI
DKEALSILKNHVENMRKHHEILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTS
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNYLIRLCHERTYTVDTTAAGGN
ASLMSIPEEG

Specific function: Oxidizes proline to glutamate for use as a carbon and nitrogen source and also function as a transcriptional repressor of the put operon [H]

COG id: COG4230

COG function: function code C; Delta 1-pyrroline-5-carboxylate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the aldehyde dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI25777732, Length=446, Percent_Identity=30.9417040358744, Blast_Score=202, Evalue=1e-51,
Organism=Homo sapiens, GI21361176, Length=475, Percent_Identity=30.7368421052632, Blast_Score=199, Evalue=1e-50,
Organism=Homo sapiens, GI25777730, Length=445, Percent_Identity=32.1348314606742, Blast_Score=197, Evalue=4e-50,
Organism=Homo sapiens, GI25777724, Length=440, Percent_Identity=31.3636363636364, Blast_Score=195, Evalue=2e-49,
Organism=Homo sapiens, GI153266822, Length=446, Percent_Identity=30.4932735426009, Blast_Score=193, Evalue=9e-49,
Organism=Homo sapiens, GI25777736, Length=508, Percent_Identity=31.2992125984252, Blast_Score=190, Evalue=6e-48,
Organism=Homo sapiens, GI25777734, Length=508, Percent_Identity=31.2992125984252, Blast_Score=190, Evalue=6e-48,
Organism=Homo sapiens, GI238859541, Length=491, Percent_Identity=31.3645621181263, Blast_Score=186, Evalue=1e-46,
Organism=Homo sapiens, GI12007648, Length=442, Percent_Identity=28.9592760180996, Blast_Score=182, Evalue=1e-45,
Organism=Homo sapiens, GI25777728, Length=408, Percent_Identity=31.1274509803922, Blast_Score=179, Evalue=2e-44,
Organism=Homo sapiens, GI238814322, Length=420, Percent_Identity=29.2857142857143, Blast_Score=177, Evalue=7e-44,
Organism=Homo sapiens, GI21614513, Length=415, Percent_Identity=29.1566265060241, Blast_Score=175, Evalue=2e-43,
Organism=Homo sapiens, GI188035924, Length=469, Percent_Identity=28.7846481876333, Blast_Score=167, Evalue=6e-41,
Organism=Homo sapiens, GI310128103, Length=443, Percent_Identity=29.1196388261851, Blast_Score=166, Evalue=8e-41,
Organism=Homo sapiens, GI310128093, Length=443, Percent_Identity=29.1196388261851, Blast_Score=166, Evalue=9e-41,
Organism=Homo sapiens, GI115387104, Length=435, Percent_Identity=27.1264367816092, Blast_Score=159, Evalue=2e-38,
Organism=Homo sapiens, GI25952152, Length=442, Percent_Identity=28.0542986425339, Blast_Score=151, Evalue=4e-36,
Organism=Homo sapiens, GI25777726, Length=443, Percent_Identity=27.9909706546275, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI310128091, Length=443, Percent_Identity=27.765237020316, Blast_Score=144, Evalue=5e-34,
Organism=Homo sapiens, GI4507229, Length=489, Percent_Identity=27.19836400818, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI11095441, Length=418, Percent_Identity=27.2727272727273, Blast_Score=130, Evalue=9e-30,
Organism=Homo sapiens, GI25777721, Length=502, Percent_Identity=26.2948207171315, Blast_Score=125, Evalue=3e-28,
Organism=Homo sapiens, GI310128087, Length=265, Percent_Identity=29.811320754717, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI310128089, Length=335, Percent_Identity=29.5522388059701, Blast_Score=112, Evalue=1e-24,
Organism=Homo sapiens, GI206597441, Length=446, Percent_Identity=23.542600896861, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI206597439, Length=446, Percent_Identity=23.542600896861, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI22907049, Length=446, Percent_Identity=23.542600896861, Blast_Score=106, Evalue=1e-22,
Organism=Homo sapiens, GI4502043, Length=426, Percent_Identity=23.2394366197183, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI238814371, Length=426, Percent_Identity=23.2394366197183, Blast_Score=104, Evalue=4e-22,
Organism=Homo sapiens, GI71773324, Length=323, Percent_Identity=25.077399380805, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI310128095, Length=310, Percent_Identity=29.0322580645161, Blast_Score=100, Evalue=6e-21,
Organism=Homo sapiens, GI73695881, Length=340, Percent_Identity=25.2941176470588, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI73695879, Length=340, Percent_Identity=25.2941176470588, Blast_Score=97, Evalue=8e-20,
Organism=Homo sapiens, GI310128097, Length=257, Percent_Identity=30.7392996108949, Blast_Score=97, Evalue=1e-19,
Organism=Homo sapiens, GI301500698, Length=281, Percent_Identity=27.4021352313167, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI73466520, Length=406, Percent_Identity=23.8916256157635, Blast_Score=93, Evalue=1e-18,
Organism=Homo sapiens, GI4557303, Length=406, Percent_Identity=23.8916256157635, Blast_Score=93, Evalue=2e-18,
Organism=Homo sapiens, GI310128099, Length=218, Percent_Identity=27.5229357798165, Blast_Score=91, Evalue=4e-18,
Organism=Homo sapiens, GI310128101, Length=215, Percent_Identity=26.9767441860465, Blast_Score=89, Evalue=2e-17,
Organism=Escherichia coli, GI1787250, Length=1044, Percent_Identity=51.4367816091954, Blast_Score=1037, Evalue=0.0,
Organism=Escherichia coli, GI1789015, Length=448, Percent_Identity=29.6875, Blast_Score=179, Evalue=9e-46,
Organism=Escherichia coli, GI1787715, Length=411, Percent_Identity=30.1703163017032, Blast_Score=172, Evalue=1e-43,
Organism=Escherichia coli, GI87081896, Length=466, Percent_Identity=28.755364806867, Blast_Score=170, Evalue=4e-43,
Organism=Escherichia coli, GI1788042, Length=427, Percent_Identity=30.9133489461358, Blast_Score=166, Evalue=9e-42,
Organism=Escherichia coli, GI1787684, Length=465, Percent_Identity=29.247311827957, Blast_Score=157, Evalue=4e-39,
Organism=Escherichia coli, GI87082295, Length=441, Percent_Identity=29.7052154195011, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI1787558, Length=430, Percent_Identity=29.3023255813954, Blast_Score=153, Evalue=5e-38,
Organism=Escherichia coli, GI1786504, Length=452, Percent_Identity=26.7699115044248, Blast_Score=137, Evalue=3e-33,
Organism=Escherichia coli, GI87081926, Length=404, Percent_Identity=26.4851485148515, Blast_Score=132, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17534447, Length=522, Percent_Identity=30.8429118773946, Blast_Score=199, Evalue=8e-51,
Organism=Caenorhabditis elegans, GI115534176, Length=452, Percent_Identity=32.5221238938053, Blast_Score=186, Evalue=6e-47,
Organism=Caenorhabditis elegans, GI17562198, Length=445, Percent_Identity=30.561797752809, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI133930964, Length=437, Percent_Identity=30.6636155606407, Blast_Score=178, Evalue=1e-44,
Organism=Caenorhabditis elegans, GI115532534, Length=392, Percent_Identity=31.3775510204082, Blast_Score=175, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI25144435, Length=443, Percent_Identity=29.7968397291196, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI32564736, Length=408, Percent_Identity=30.3921568627451, Blast_Score=164, Evalue=3e-40,
Organism=Caenorhabditis elegans, GI25143874, Length=456, Percent_Identity=28.0701754385965, Blast_Score=163, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI25143876, Length=456, Percent_Identity=28.0701754385965, Blast_Score=162, Evalue=1e-39,
Organism=Caenorhabditis elegans, GI32564151, Length=468, Percent_Identity=28.8461538461538, Blast_Score=155, Evalue=1e-37,
Organism=Caenorhabditis elegans, GI17551164, Length=437, Percent_Identity=27.6887871853547, Blast_Score=154, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI71995606, Length=439, Percent_Identity=26.1958997722096, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI71995613, Length=396, Percent_Identity=26.010101010101, Blast_Score=134, Evalue=2e-31,
Organism=Caenorhabditis elegans, GI17534119, Length=441, Percent_Identity=26.530612244898, Blast_Score=133, Evalue=5e-31,
Organism=Caenorhabditis elegans, GI71986308, Length=417, Percent_Identity=26.378896882494, Blast_Score=130, Evalue=5e-30,
Organism=Caenorhabditis elegans, GI71990744, Length=369, Percent_Identity=29.2682926829268, Blast_Score=120, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI25146391, Length=415, Percent_Identity=23.6144578313253, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI25146394, Length=415, Percent_Identity=23.6144578313253, Blast_Score=99, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI32566756, Length=415, Percent_Identity=23.6144578313253, Blast_Score=99, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI17564084, Length=419, Percent_Identity=23.3890214797136, Blast_Score=94, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320917, Length=443, Percent_Identity=33.4085778781038, Blast_Score=194, Evalue=5e-50,
Organism=Saccharomyces cerevisiae, GI6321826, Length=519, Percent_Identity=29.6724470134875, Blast_Score=186, Evalue=1e-47,
Organism=Saccharomyces cerevisiae, GI6324950, Length=433, Percent_Identity=32.3325635103926, Blast_Score=186, Evalue=2e-47,
Organism=Saccharomyces cerevisiae, GI6325196, Length=441, Percent_Identity=30.3854875283447, Blast_Score=185, Evalue=3e-47,
Organism=Saccharomyces cerevisiae, GI6323821, Length=462, Percent_Identity=30.952380952381, Blast_Score=183, Evalue=1e-46,
Organism=Saccharomyces cerevisiae, GI6323822, Length=447, Percent_Identity=29.7539149888143, Blast_Score=182, Evalue=3e-46,
Organism=Saccharomyces cerevisiae, GI6319478, Length=445, Percent_Identity=26.5168539325843, Blast_Score=142, Evalue=2e-34,
Organism=Saccharomyces cerevisiae, GI6321828, Length=506, Percent_Identity=24.3083003952569, Blast_Score=124, Evalue=7e-29,
Organism=Saccharomyces cerevisiae, GI6323757, Length=326, Percent_Identity=26.3803680981595, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI20129399, Length=445, Percent_Identity=32.3595505617978, Blast_Score=207, Evalue=3e-53,
Organism=Drosophila melanogaster, GI24668425, Length=532, Percent_Identity=28.7593984962406, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24668417, Length=532, Percent_Identity=28.7593984962406, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI24668413, Length=532, Percent_Identity=28.7593984962406, Blast_Score=195, Evalue=1e-49,
Organism=Drosophila melanogaster, GI281362580, Length=443, Percent_Identity=30.6997742663657, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62472918, Length=443, Percent_Identity=30.6997742663657, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62472926, Length=443, Percent_Identity=30.6997742663657, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI62472936, Length=443, Percent_Identity=30.6997742663657, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI21356737, Length=443, Percent_Identity=30.6997742663657, Blast_Score=179, Evalue=1e-44,
Organism=Drosophila melanogaster, GI24650465, Length=448, Percent_Identity=29.9107142857143, Blast_Score=176, Evalue=7e-44,
Organism=Drosophila melanogaster, GI24666674, Length=466, Percent_Identity=28.9699570815451, Blast_Score=164, Evalue=4e-40,
Organism=Drosophila melanogaster, GI24585660, Length=443, Percent_Identity=27.765237020316, Blast_Score=164, Evalue=4e-40,
Organism=Drosophila melanogaster, GI28574525, Length=509, Percent_Identity=27.5049115913556, Blast_Score=157, Evalue=3e-38,
Organism=Drosophila melanogaster, GI28571802, Length=502, Percent_Identity=25.8964143426295, Blast_Score=143, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571800, Length=502, Percent_Identity=25.8964143426295, Blast_Score=143, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571806, Length=502, Percent_Identity=25.8964143426295, Blast_Score=142, Evalue=8e-34,
Organism=Drosophila melanogaster, GI28571798, Length=502, Percent_Identity=25.8964143426295, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI28571796, Length=502, Percent_Identity=25.8964143426295, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI28571794, Length=502, Percent_Identity=25.8964143426295, Blast_Score=142, Evalue=9e-34,
Organism=Drosophila melanogaster, GI24638876, Length=419, Percent_Identity=26.491646778043, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24638878, Length=419, Percent_Identity=26.491646778043, Blast_Score=112, Evalue=2e-24,
Organism=Drosophila melanogaster, GI281360303, Length=439, Percent_Identity=24.373576309795, Blast_Score=94, Evalue=7e-19,
Organism=Drosophila melanogaster, GI45552499, Length=434, Percent_Identity=23.5023041474654, Blast_Score=93, Evalue=8e-19,
Organism=Drosophila melanogaster, GI281360301, Length=439, Percent_Identity=24.373576309795, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281360299, Length=434, Percent_Identity=23.5023041474654, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281360297, Length=434, Percent_Identity=23.5023041474654, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI281360295, Length=434, Percent_Identity=23.5023041474654, Blast_Score=91, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24586250, Length=434, Percent_Identity=23.5023041474654, Blast_Score=91, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016161
- InterPro:   IPR016163
- InterPro:   IPR016160
- InterPro:   IPR016162
- InterPro:   IPR015590
- InterPro:   IPR005933
- InterPro:   IPR002872 [H]

Pfam domain/function: PF00171 Aldedh; PF01619 Pro_dh [H]

EC number: =1.5.99.8; =1.5.1.12 [H]

Molecular weight: Translated: 116102; Mature: 116102

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS00070 ALDEHYDE_DEHYDR_CYS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RKKSTGIDSFLTEYALSSDEGIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQS
HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
ESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSSEAVVRKAVDKAMRIMSKQFV
CCEEEEHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
HCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VYRRPGISIKLSALHPRYSEFQYERVMAELPPKLLALSRLAKDYGIALTIDAEESERLDL
HHHCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCC
SLDVIEKVFTDESLQGWNGFGLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDAIYPQFATHNAYSVAMILNLV
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHH
GGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
CCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHH
FVNRIVDDKAPISELVEDPVAKSRSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHH
LLQQELAKIESKEWQASPMIAGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQ
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHH
AKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCREAGKTWSDGIAEVREAIDFC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RYYAKKAQELMSSPQRFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
HHHHHHHHHHHCCCHHCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGST
EEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCC
DTANLINRTLATRGGEIIPLIAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSAL
CHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHH
RVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVIDKEALSILKNHVENMRKHHE
EEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTS
HHEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNY
CCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEECCCCCCCCCCCCCCCCCCCHH
LIRLCHERTYTVDTTAAGGNASLMSIPEEG
HHHHHHCCCEEEEECCCCCCCEEECCCCCC
>Mature Secondary Structure
MLEKQSIHLPEGLRAAINKAYRMDELSLITELSEQAALDPQQMMAIKTSATKLVQSVRSE
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
RKKSTGIDSFLTEYALSSDEGIALMCLAEALLRVPDNATIDNLIKDKLAGGDWGAHRGQS
HHHHCCHHHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
ESFFVNATTWALMLTGKVLTPEKAENTLTKALLKLVNRSSEAVVRKAVDKAMRIMSKQFV
CCEEEEHHEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
MGRTINEALARAKKKEDRGYRYSYDMLGEAALTSADAARYFEAYKEAIISIGEKADKHSD
HCCHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCH
VYRRPGISIKLSALHPRYSEFQYERVMAELPPKLLALSRLAKDYGIALTIDAEESERLDL
HHHCCCCEEEEEECCCCHHHHHHHHHHHHCCHHHHHHHHHHHHCCEEEEEECCCCCCCCC
SLDVIEKVFTDESLQGWNGFGLAVQSYQKRAFYVLDWVAALARSKQRRIMVRLIKGAYWD
HHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
SEIKKTQMQGFSEYPVFTRKVFTDVSFQACAKKILTMTDAIYPQFATHNAYSVAMILNLV
HHHHHHHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHHH
GGYRDFEFQCLHGMGNELYEQIVPANCYGIPCRIYAPVGSHEDLLPYLVRRLLENGANSS
CCCCCCHHHHHHHCCHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHCCCCHH
FVNRIVDDKAPISELVEDPVAKSRSLLDKINKNIPLPEDIFLPVRKNSKGFDFTNRLERA
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCHHHHHHHH
LLQQELAKIESKEWQASPMIAGRKLSRDLLQTVMSPQQPAYAIGSVQQATLDDVEVALNQ
HHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHCCCHHHHHHHHHHHHHH
AKLAFELWSKKPVEERASCLNRFADLLQANMAELMVLTCREAGKTWSDGIAEVREAIDFC
HHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHH
RYYAKKAQELMSSPQRFNGYTGELNELSLHPRGTILCISPWNFPLAIFTGQVVAGLVTGN
HHHHHHHHHHHCCCHHCCCCCCCCCCEEECCCCEEEEECCCCCCHHHHHHHHHHHHHCCC
CVIAKPAEQTPLIAAYAVKLMHQAGIPEGVIQLIPGAGETIGAALVADKRIKAVLFTGST
EEEECCCCCCCHHHHHHHHHHHHCCCCHHHHHHCCCCCCHHHHHHHHCCCEEEEEEECCC
DTANLINRTLATRGGEIIPLIAETGGQNAMIVDSSALLEQVVVDAVTSAFGSAGQRCSAL
CHHHHHHHHHHHCCCCEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHCCCCHHHHH
RVLYVQEEVYPRTVELLKGAMAELVVGDPQWLSTDVGPVIDKEALSILKNHVENMRKHHE
EEEEEHHHHHHHHHHHHHHHHHHHHCCCCCHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILYQCTVDDEALSGYFMPPTAIAIDSISALEKEVFGPILHVIQFKRKDLDKVINQINQTS
HHEEEECCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
YGLTLGIHSRINETVDYIRQRVHAGNCYVNRNMIGAVVGLQPFGGEGLSGTGPKAGGPNY
CCEEEEHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHEECCCCCCCCCCCCCCCCCCCHH
LIRLCHERTYTVDTTAAGGNASLMSIPEEG
HHHHHHCCCEEEEECCCCCCCEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7966312; 8905232; 9278503; 3325781; 12514740 [H]