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The map label for this gene is truD [H]

Identifier: 148359158

GI number: 148359158

Start: 1859625

End: 1860641

Strand: Reverse

Name: truD [H]

Synonym: LPC_1050

Alternate gene names: 148359158

Gene position: 1860641-1859625 (Counterclockwise)

Preceding gene: 148359160

Following gene: 148359157

Centisome position: 52.02

GC content: 38.84

Gene sequence:

>1017_bases
ATGTACTCTTTGGATTGGCCACGAGCCTATGGCATACCAAACTCTACAGCTACTTTTAAGTCGTTGCCGGAAGATTTTCA
AGTGAATGAATTGTTTGAAGGACAATTTAATGGTGAAGGAGAGCACATAGTTCTTAAAATTGAAAAAAGAGGATTAACTA
CCGAAGAAGTTGTTAAATCATTAGCCAGGTTAATTAATAAACCCGTAAAACTTATAAGTCATGCTGGATTAAAGGATAAA
CAGGCATTAACAACTCAATGGCTCAGTGTTCATGCACCTGGGGAGATAATCGATGGCATAGAAACACTAGAAGCGCCAGG
TTGGAGAATACTGGAATGTACACGCCATAACAAAAAACTCAAACCAGGTTTTTTATCGGGCAATCATTTTATAATCACTT
TAAGAAATGTCTCTGATGAGAGTGATCTAATACATCGTATTGAACAAATTAAATTTAAAGGTGTTCCAAATTATTTCGGT
GAGCAGCGTTTTGGTCGAGATGGTGGAAATTTAATTAAAGCAGAGGAAATACTAGTACAGGGGCGCAAAGTAAAGGATAG
ATTTTTAAAGGGAATGTATTTTTCTGCAGCCCGATCATGGCTATATAATTTGATCCTGTCTCGCCGTGTAAAGGAATCAT
CATGGAATTTGCCCTTATTGGGGGATGTCATACAGCTTGTTGGATCAAACAGTATATTTGTTAATGATAAAAGCATGGAC
GAGCAATTGTTGCAACGAATCGGTGAAAAAGATGTTTCTCCAGCAAGCCCTCTGCCTGGTAGGAGTAAGAATCTTGTAAA
AGGGACAGCTTTGCAAATAATAAACGACGTTTATGAGGAATGGTCTGCTTGGCTTGATGGGTTAGAAAAAAATGGTTTGG
AAGAAGCCTGGCGTGCAAACATCCTTTATGCAGAGCAGATTGAATATAGGATAAACCAAGGTACAGTTGAGCTTTCGTTT
GTCTTGCCGGCTGGCGCTTACGCGACAGTGGTATTACGTGAACTGGTTCAATATTAA

Upstream 100 bases:

>100_bases
AAGAGATGCATTATCTCAACTAATAAGTTCTGTATCTCTGTGAGCTTATAGTGAATTTGTGGATTTAGTTTAGAACCCTT
TTTTGTTGAAGGAGATCTTG

Downstream 100 bases:

>100_bases
GCTTTGTTTGCACTTGAATAGCACTTTATTCGATGTTGAGTAATTATTTTTTAATTGAATTGATGAATTAATCACTATGT
TTGATGTTATGCCATAATTA

Product: hydrogenase

Products: NA

Alternate protein names: tRNA pseudouridylate synthase D; tRNA-uridine isomerase D [H]

Number of amino acids: Translated: 338; Mature: 338

Protein sequence:

>338_residues
MYSLDWPRAYGIPNSTATFKSLPEDFQVNELFEGQFNGEGEHIVLKIEKRGLTTEEVVKSLARLINKPVKLISHAGLKDK
QALTTQWLSVHAPGEIIDGIETLEAPGWRILECTRHNKKLKPGFLSGNHFIITLRNVSDESDLIHRIEQIKFKGVPNYFG
EQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSMD
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINDVYEEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSF
VLPAGAYATVVLRELVQY

Sequences:

>Translated_338_residues
MYSLDWPRAYGIPNSTATFKSLPEDFQVNELFEGQFNGEGEHIVLKIEKRGLTTEEVVKSLARLINKPVKLISHAGLKDK
QALTTQWLSVHAPGEIIDGIETLEAPGWRILECTRHNKKLKPGFLSGNHFIITLRNVSDESDLIHRIEQIKFKGVPNYFG
EQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSMD
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINDVYEEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSF
VLPAGAYATVVLRELVQY
>Mature_338_residues
MYSLDWPRAYGIPNSTATFKSLPEDFQVNELFEGQFNGEGEHIVLKIEKRGLTTEEVVKSLARLINKPVKLISHAGLKDK
QALTTQWLSVHAPGEIIDGIETLEAPGWRILECTRHNKKLKPGFLSGNHFIITLRNVSDESDLIHRIEQIKFKGVPNYFG
EQRFGRDGGNLIKAEEILVQGRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSMD
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINDVYEEWSAWLDGLEKNGLEEAWRANILYAEQIEYRINQGTVELSF
VLPAGAYATVVLRELVQY

Specific function: Responsible for synthesis of pseudouridine from uracil- 13 in transfer RNAs [H]

COG id: COG0585

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRUD domain [H]

Homologues:

Organism=Escherichia coli, GI1789102, Length=328, Percent_Identity=37.5, Blast_Score=209, Evalue=2e-55,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020103
- InterPro:   IPR001656
- InterPro:   IPR020119
- InterPro:   IPR011760 [H]

Pfam domain/function: PF01142 TruD [H]

EC number: NA

Molecular weight: Translated: 38310; Mature: 38310

Theoretical pI: Translated: 7.17; Mature: 7.17

Prosite motif: PS50984 TRUD ; PS01268 UPF0024

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYSLDWPRAYGIPNSTATFKSLPEDFQVNELFEGQFNGEGEHIVLKIEKRGLTTEEVVKS
CCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHH
LARLINKPVKLISHAGLKDKQALTTQWLSVHAPGEIIDGIETLEAPGWRILECTRHNKKL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
KPGFLSGNHFIITLRNVSDESDLIHRIEQIKFKGVPNYFGEQRFGRDGGNLIKAEEILVQ
CCCEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEHHHHHHHC
GRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSMD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCHHH
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINDVYEEWSAWLDGLEKNGLEEAWRAN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
ILYAEQIEYRINQGTVELSFVLPAGAYATVVLRELVQY
CEEHHHHHEEECCCEEEEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure
MYSLDWPRAYGIPNSTATFKSLPEDFQVNELFEGQFNGEGEHIVLKIEKRGLTTEEVVKS
CCCCCCCCCCCCCCCCHHHHCCCCCCCHHHHHCCCCCCCCCEEEEEEECCCCCHHHHHHH
LARLINKPVKLISHAGLKDKQALTTQWLSVHAPGEIIDGIETLEAPGWRILECTRHNKKL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHEECCCHHHHHHHHHHCCCCCEEEEECCCCCCC
KPGFLSGNHFIITLRNVSDESDLIHRIEQIKFKGVPNYFGEQRFGRDGGNLIKAEEILVQ
CCCEECCCEEEEEEECCCCHHHHHHHHHHHHHCCCCCHHHHHHCCCCCCCEEHHHHHHHC
GRKVKDRFLKGMYFSAARSWLYNLILSRRVKESSWNLPLLGDVIQLVGSNSIFVNDKSMD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCHHH
EQLLQRIGEKDVSPASPLPGRSKNLVKGTALQIINDVYEEWSAWLDGLEKNGLEEAWRAN
HHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCC
ILYAEQIEYRINQGTVELSFVLPAGAYATVVLRELVQY
CEEHHHHHEEECCCEEEEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA