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The map label for this gene is ruvB

Identifier: 148359112

GI number: 148359112

Start: 1808930

End: 1809886

Strand: Reverse

Name: ruvB

Synonym: LPC_1000

Alternate gene names: 148359112

Gene position: 1809886-1808930 (Counterclockwise)

Preceding gene: 148359113

Following gene: 148359111

Centisome position: 50.61

GC content: 42.01

Gene sequence:

>957_bases
ATGGATAGAGCCATCAGGCCGCTTAGCTTGAGCGAGTACGTAGGGCAAGATTCTGTAAGCTCACAGATGCAGATATTTAT
CAATGCGGCAAGAAAGAGAAACGATCCTTTGGATCATGTTCTTATTTTTGGCCCACCTGGCCTTGGTAAAACTACTCTGG
CAAATATCATAGCTCACGAAATGGGAGTGAATATCAGACAAACTTCTGGGCCAGTGATTGAGCGTGCTGGCGATATTGCT
GCTATATTGACGAATCTACAACAAAATGATGTACTATTTATTGATGAAATTCATAGATTAAGTCCTGTTATAGAAGAAAT
TCTTTATCCAGCCATGGAAGATTATAAGTTGGATATCATGATAGGAGAGGGGCCAGCAGCACGATCTATTAAATTGGAGT
TACCTCCCTTTACATTAATTGGAGCAACGACGAGAGCAGGGTTGCTTACCTCGCCATTAAGGGATAGATTTGGTATAGTG
CAACGTTTGGAATATTATTCTGTTGATTCGCTTACCAAGATTGTGGCACGCTCTGCGCATTTGCTTGGTGTCCCTACAAA
ACCCGAAGGAGCCAGAGAAATTGCATTACGCTCCAGAGGAACACCACGAATAGCCAATCGCCTGTTAAGAAGAGTCAGGG
ATTATTCTGAAGTGAAAGGAAATGGCATCATTACTGTTGATATGGCCCAACAAGCATTGGAAATGCTTGAAGTGGATCAG
CACGGGTTTGATTTAATGGATAGAAAATTATTGTTAGCGGTGATAGAACACTTCAATGGTGGTCCAGTAGGCATAGATAG
TATTGCAGCTGCTATTGGCGAAGAAAAAGGGACTATAGAAGATGTTTTAGAGCCATTTTTAATACAACAAGGCTTTCTAA
TGCGCACTCCTCGCGGTAGAATAGCCACTTCGAAAGCTTATCAGCACTTTGGCTTTAGTGCGATCGAACAGGAATAA

Upstream 100 bases:

>100_bases
CCTATGTTAAAATGCTTTCATTCGAATGAACCCGATAAAACCTCTTATGCTCGAAAGTGATCGCCTAATAAGTAGTCAAA
GTATTGTCTCGGAAGACGCA

Downstream 100 bases:

>100_bases
CACATGAATCTTATATCAGATCATCAGCATAACATTAGAGTCTATGCAGAAGATGTTGATTATATGGGAATTGTTTATCA
TGCTAACTACCTTTGTTATT

Product: Holliday junction DNA helicase RuvB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIA
AILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIV
QRLEYYSVDSLTKIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQ
HGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE

Sequences:

>Translated_318_residues
MDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIA
AILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIV
QRLEYYSVDSLTKIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQ
HGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE
>Mature_318_residues
MDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHEMGVNIRQTSGPVIERAGDIA
AILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIMIGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIV
QRLEYYSVDSLTKIVARSAHLLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQ
HGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGRIATSKAYQHFGFSAIEQE

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG2255

COG function: function code L; Holliday junction resolvasome, helicase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvB family

Homologues:

Organism=Escherichia coli, GI1788167, Length=315, Percent_Identity=73.6507936507937, Blast_Score=478, Evalue=1e-136,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVB_LEGPA (Q5X4Y6)

Other databases:

- EMBL:   CR628336
- RefSeq:   YP_123858.1
- ProteinModelPortal:   Q5X4Y6
- SMR:   Q5X4Y6
- STRING:   Q5X4Y6
- GeneID:   3117521
- GenomeReviews:   CR628336_GR
- KEGG:   lpp:lpp1534
- LegioList:   lpp1534
- eggNOG:   COG2255
- HOGENOM:   HBG339960
- OMA:   EKFDGGP
- ProtClustDB:   PRK00080
- BioCyc:   LPNE297246:LPP1534-MONOMER
- HAMAP:   MF_00016
- InterPro:   IPR003593
- InterPro:   IPR004605
- InterPro:   IPR008823
- InterPro:   IPR008824
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- ProDom:   PD005323
- SMART:   SM00382
- TIGRFAMs:   TIGR00635

Pfam domain/function: PF05491 RuvB_C; PF05496 RuvB_N

EC number: =3.6.4.12

Molecular weight: Translated: 35143; Mature: 35143

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHE
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
MGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIM
HCCCEEECCCCHHHHCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEE
IGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTKIVARSAH
ECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQ
EEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCC
HGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGR
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCC
IATSKAYQHFGFSAIEQE
CHHHHHHHHCCCHHHCCC
>Mature Secondary Structure
MDRAIRPLSLSEYVGQDSVSSQMQIFINAARKRNDPLDHVLIFGPPGLGKTTLANIIAHE
CCCCCCCCCHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHHH
MGVNIRQTSGPVIERAGDIAAILTNLQQNDVLFIDEIHRLSPVIEEILYPAMEDYKLDIM
HCCCEEECCCCHHHHCCHHHHHHHCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCEEEEE
IGEGPAARSIKLELPPFTLIGATTRAGLLTSPLRDRFGIVQRLEYYSVDSLTKIVARSAH
ECCCCCCCEEEEECCCEEEEECCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLGVPTKPEGAREIALRSRGTPRIANRLLRRVRDYSEVKGNGIITVDMAQQALEMLEVDQ
EEECCCCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHCC
HGFDLMDRKLLLAVIEHFNGGPVGIDSIAAAIGEEKGTIEDVLEPFLIQQGFLMRTPRGR
CCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCEEECCCCC
IATSKAYQHFGFSAIEQE
CHHHHHHHHCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA