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The map label for this gene is yciR [C]

Identifier: 148358488

GI number: 148358488

Start: 382511

End: 384736

Strand: Reverse

Name: yciR [C]

Synonym: LPC_0354

Alternate gene names: 148358488

Gene position: 384736-382511 (Counterclockwise)

Preceding gene: 148358489

Following gene: 148358483

Centisome position: 10.76

GC content: 39.62

Gene sequence:

>2226_bases
ATGAGTACTGAATCTTTTCGCATTCTGGTCATTGATGACAACCCGGCAATCCATCAGGATTTTATGAAAATCTTAAATGT
CAGCAAGAACTCTGCTTTACTAAATAAATTTGATGCCGAGCTGTTTGATGATGAGACAGAACAACTTGGCATTTCTTTGC
CTGAATTTGAAATCGATGTAGCGACTCAAGGCATTGAGGGCATAGAAAAAGTGAAACGTTCACTTGAAGAAGGACGGCCA
TACCCACTCGCCTTTGTTGACATAAGAATGCCCCCGGGGATAGATGGGGTAGAAACCATCAAGCGCATTTGGGCCATTGA
CCCGCAAATACAGATTGTAATATGCAGTGCCTATTCCGATTACTCATGGGAAAGCACAGTGAATACCCTGGGTTTAAGTG
ATAATTTATTGGTGCTAAAAAAACCCTTTGATGTGATTGCCGTAAGACAGTTGGCAAGTGCTTTGACACAAAAATGGGTA
CTTGCCAGGGAAACTCAAAAACACACTGAATTTTTAAATCAATTGGTAGAAGAACGAACCGAATCTTTGCAGCAATCCTT
CTCCTTATTGAGAGCAACGATTGAGTCCTCTTCGGATGGCATTCTGGTTGTCGATTTACAAGGAAAAATCGTTGATTACA
ACTCTCAATTCGTCAAATTATGGAATATACCCGAATCCATCATAAAAAAAGAAACCAGTGAGCCCCAACTCATTCAGTAT
ATGTCAACTCAATTACTCAATTCAGAACAGCATGCCCAACATGTTAAAGAATTTTCTATTCACATCGATGATTCCAGCAT
GCAAATTTATCATTTTAGAAATGGTAAAGTGGTTGAATGCTGTTCCAAACCGCATCGCGTTGGTCTGCAAACGGTAGGCC
GTGTATGGAGCTTCAGAGACATCACTGAACAAACGCGATTAAAGGAAAAACTGGAGTATCAAGCCACTCATGACGCATTA
ACCAATTTACCCAATCGCTTGTTATTAATTGATCGTATTGAACATGCTATCAGTGGCTATGCCCGCCATAAAATGAAATT
TGCCATATTATTTTTTGACTTGGACCGCTTTAAAATGATCAATGACAGCTTGAGCCATGAAGCAGGCGATCAATTACTGT
GTGCCGTTGCTGAACGATTACGATCTTTGGTGCGAAAAGAAGATACTCTCGCCAGACTTGGTGGGGATGAGTTTGTAATG
CTTTTTCAATCGTTTAATTCTGAAGAGCAAATTGCCGGAGTAGCTCAAAAAATCCTCAAATCCTTTCAAAAACCATTTCA
TATTGCTGAAAGAGACATCAATATTCATGTCAGCATAGGTATTAGCGTTTATCCAACGGATGGCAAAACAGTAAACACTT
TACTCAGTAATGCGGATATGGCGATGTATCAGGCAAAATTTCGAGGTGGTAACCAATTCTCATTTTATACAGAGAAACTC
AACAAAAAAACAAACCAGCAATTTCAGCTGGAATTAGACTTGCAAAAAGCGATTGTCCATCATGAGTTTTTCCTCCTTTA
CCAGCCTCAATTTACAGTTAATACTCATGAGATTCGTTCCATGGAAGCATTAATCCGGTGGAATCACCCGCAAAAAGGTA
TTATTTTACCCTTGGATTTTATTCCTACTGCCGAAAGTTCAGGGCTTATCGTACCGATAGGAGAGTGGGTTTTGCGGGAA
ACCTGTAAGCAAATTGGTGCGTGGCGCACAATGGGGCTGCCTGAAATTCGTGTCGCTTGTAATGTAGCAAGTAAACAGTT
AAGACAACGCGACTTCCCTGCAATGGTGGAGGATCTTTTAAAAGAATATTCAGTCGAACCTCATTGTCTGGAGCTGGAAA
TTACTGAAAATGTGATTATTGATAAAGAAATACAAAGAACGATCAAAAAATTGAAATCACTCGGTGTGTTGATTATTTTG
GATGATTTTGGCACAGGAAATTCCAGCCTGAATTTATTAAAGCAGGTCGCTGTTGATAGCCTAAAAATAGACCAATCATT
CATTCAGAATATTTCAAAATCGCCAGGAGATGAAGCGATCATCGATGCGATTATTGCTATCGCACAAAGCATGAATTTTA
ATATCATCGCCGAAGGAGTCGAAACGCAGAACCAGCTTAAATTCCTCAAGAAAAGGCGGTGTAATGACATTCAAGGCTTT
TTAATGAGTAAGCCTATACCACCAGAAGAGATAGAAAAACTTCTGCAAGGAAATAGGACAAAATAA

Upstream 100 bases:

>100_bases
TGGGTGGTACACTTTATGCTGAAAGCAATGGCAATGGCGAAGGAGCTCAATTTGTATTAGATTTGCCCATCAATCCCAAA
ACCTTAAGTCCGAGGTAGAA

Downstream 100 bases:

>100_bases
GGTAAAAATCGCATTGGCATCTATAAGAGCTATCCGATGGATTGCAATTATAGATGCAAGACAAACTACACCGTAATCAT
AACGGTTTGATTACGTAAAT

Product: GGDEF domain-containing sensory box protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 741; Mature: 740

Protein sequence:

>741_residues
MSTESFRILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFDDETEQLGISLPEFEIDVATQGIEGIEKVKRSLEEGRP
YPLAFVDIRMPPGIDGVETIKRIWAIDPQIQIVICSAYSDYSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWV
LARETQKHTEFLNQLVEERTESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIIKKETSEPQLIQY
MSTQLLNSEQHAQHVKEFSIHIDDSSMQIYHFRNGKVVECCSKPHRVGLQTVGRVWSFRDITEQTRLKEKLEYQATHDAL
TNLPNRLLLIDRIEHAISGYARHKMKFAILFFDLDRFKMINDSLSHEAGDQLLCAVAERLRSLVRKEDTLARLGGDEFVM
LFQSFNSEEQIAGVAQKILKSFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKL
NKKTNQQFQLELDLQKAIVHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFIPTAESSGLIVPIGEWVLRE
TCKQIGAWRTMGLPEIRVACNVASKQLRQRDFPAMVEDLLKEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIIL
DDFGTGNSSLNLLKQVAVDSLKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGF
LMSKPIPPEEIEKLLQGNRTK

Sequences:

>Translated_741_residues
MSTESFRILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFDDETEQLGISLPEFEIDVATQGIEGIEKVKRSLEEGRP
YPLAFVDIRMPPGIDGVETIKRIWAIDPQIQIVICSAYSDYSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWV
LARETQKHTEFLNQLVEERTESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIIKKETSEPQLIQY
MSTQLLNSEQHAQHVKEFSIHIDDSSMQIYHFRNGKVVECCSKPHRVGLQTVGRVWSFRDITEQTRLKEKLEYQATHDAL
TNLPNRLLLIDRIEHAISGYARHKMKFAILFFDLDRFKMINDSLSHEAGDQLLCAVAERLRSLVRKEDTLARLGGDEFVM
LFQSFNSEEQIAGVAQKILKSFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKL
NKKTNQQFQLELDLQKAIVHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFIPTAESSGLIVPIGEWVLRE
TCKQIGAWRTMGLPEIRVACNVASKQLRQRDFPAMVEDLLKEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIIL
DDFGTGNSSLNLLKQVAVDSLKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGF
LMSKPIPPEEIEKLLQGNRTK
>Mature_740_residues
STESFRILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFDDETEQLGISLPEFEIDVATQGIEGIEKVKRSLEEGRPY
PLAFVDIRMPPGIDGVETIKRIWAIDPQIQIVICSAYSDYSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWVL
ARETQKHTEFLNQLVEERTESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIIKKETSEPQLIQYM
STQLLNSEQHAQHVKEFSIHIDDSSMQIYHFRNGKVVECCSKPHRVGLQTVGRVWSFRDITEQTRLKEKLEYQATHDALT
NLPNRLLLIDRIEHAISGYARHKMKFAILFFDLDRFKMINDSLSHEAGDQLLCAVAERLRSLVRKEDTLARLGGDEFVML
FQSFNSEEQIAGVAQKILKSFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKLN
KKTNQQFQLELDLQKAIVHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDFIPTAESSGLIVPIGEWVLRET
CKQIGAWRTMGLPEIRVACNVASKQLRQRDFPAMVEDLLKEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILD
DFGTGNSSLNLLKQVAVDSLKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGFL
MSKPIPPEEIEKLLQGNRTK

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=468, Percent_Identity=37.6068376068376, Blast_Score=324, Evalue=1e-89,
Organism=Escherichia coli, GI87081921, Length=431, Percent_Identity=32.9466357308585, Blast_Score=248, Evalue=1e-66,
Organism=Escherichia coli, GI226510982, Length=419, Percent_Identity=30.3102625298329, Blast_Score=205, Evalue=9e-54,
Organism=Escherichia coli, GI87081980, Length=268, Percent_Identity=34.7014925373134, Blast_Score=151, Evalue=2e-37,
Organism=Escherichia coli, GI1790496, Length=237, Percent_Identity=32.4894514767932, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI1788502, Length=249, Percent_Identity=31.7269076305221, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI87081845, Length=259, Percent_Identity=31.2741312741313, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1786507, Length=233, Percent_Identity=33.4763948497854, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081743, Length=238, Percent_Identity=32.7731092436975, Blast_Score=129, Evalue=9e-31,
Organism=Escherichia coli, GI1788381, Length=416, Percent_Identity=27.6442307692308, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787055, Length=301, Percent_Identity=29.9003322259136, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788849, Length=239, Percent_Identity=35.1464435146443, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI87081881, Length=177, Percent_Identity=36.1581920903955, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI87081977, Length=156, Percent_Identity=36.5384615384615, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87082096, Length=260, Percent_Identity=25.7692307692308, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=35.0282485875706, Blast_Score=86, Evalue=9e-18,
Organism=Escherichia coli, GI1788085, Length=216, Percent_Identity=29.1666666666667, Blast_Score=86, Evalue=1e-17,
Organism=Escherichia coli, GI1787816, Length=171, Percent_Identity=32.7485380116959, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1786584, Length=178, Percent_Identity=26.4044943820225, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI145693134, Length=182, Percent_Identity=31.8681318681319, Blast_Score=78, Evalue=3e-15,
Organism=Escherichia coli, GI1788956, Length=167, Percent_Identity=33.5329341317365, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787802, Length=173, Percent_Identity=29.4797687861272, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=29.2682926829268, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787410, Length=127, Percent_Identity=33.8582677165354, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI87081974, Length=125, Percent_Identity=32.8, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 84544; Mature: 84413

Theoretical pI: Translated: 5.97; Mature: 5.97

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTESFRILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFDDETEQLGISLPEFEIDV
CCCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEEEH
ATQGIEGIEKVKRSLEEGRPYPLAFVDIRMPPGIDGVETIKRIWAIDPQIQIVICSAYSD
HHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCC
YSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWVLARETQKHTEFLNQLVEERT
CCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIIKKETSEPQLIQY
HHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCEEEEECCCHHHHCCCCCCHHHHHH
MSTQLLNSEQHAQHVKEFSIHIDDSSMQIYHFRNGKVVECCSKPHRVGLQTVGRVWSFRD
HHHHHHCCHHHHHHHHHHEEEEECCCEEEEEECCCCEEEECCCCHHCCHHHHHHHHHHHH
ITEQTRLKEKLEYQATHDALTNLPNRLLLIDRIEHAISGYARHKMKFAILFFDLDRFKMI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHH
NDSLSHEAGDQLLCAVAERLRSLVRKEDTLARLGGDEFVMLFQSFNSEEQIAGVAQKILK
HHHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHH
SFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKL
HHCCCCEEECCCEEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCEEHHHHHHH
NKKTNQQFQLELDLQKAIVHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDF
CCCCCCEEEEEEEHHHHHHHHEEEEEECCCEECCHHHHHHHHHHHHCCCCCCCEEEEEEC
IPTAESSGLIVPIGEWVLRETCKQIGAWRTMGLPEIRVACNVASKQLRQRDFPAMVEDLL
CCCCCCCCEEEEHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILDDFGTGNSSLNLLKQVAVDS
HHCCCCCCEEEEEECCCEEECHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHH
LKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGF
HHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHH
LMSKPIPPEEIEKLLQGNRTK
HHCCCCCHHHHHHHHCCCCCC
>Mature Secondary Structure 
STESFRILVIDDNPAIHQDFMKILNVSKNSALLNKFDAELFDDETEQLGISLPEFEIDV
CCCCEEEEEECCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCCCHHHHCCCCCCEEEEH
ATQGIEGIEKVKRSLEEGRPYPLAFVDIRMPPGIDGVETIKRIWAIDPQIQIVICSAYSD
HHCCHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHCCCCCEEEEEEECCCC
YSWESTVNTLGLSDNLLVLKKPFDVIAVRQLASALTQKWVLARETQKHTEFLNQLVEERT
CCCHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ESLQQSFSLLRATIESSSDGILVVDLQGKIVDYNSQFVKLWNIPESIIKKETSEPQLIQY
HHHHHHHHHHHHHHCCCCCCEEEEEECCCEEECCCCEEEEECCCHHHHCCCCCCHHHHHH
MSTQLLNSEQHAQHVKEFSIHIDDSSMQIYHFRNGKVVECCSKPHRVGLQTVGRVWSFRD
HHHHHHCCHHHHHHHHHHEEEEECCCEEEEEECCCCEEEECCCCHHCCHHHHHHHHHHHH
ITEQTRLKEKLEYQATHDALTNLPNRLLLIDRIEHAISGYARHKMKFAILFFDLDRFKMI
HHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHEEEEEEEEECHHHHHH
NDSLSHEAGDQLLCAVAERLRSLVRKEDTLARLGGDEFVMLFQSFNSEEQIAGVAQKILK
HHHHCHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEHHCCCHHHHHHHHHHHHH
SFQKPFHIAERDINIHVSIGISVYPTDGKTVNTLLSNADMAMYQAKFRGGNQFSFYTEKL
HHCCCCEEECCCEEEEEEEEEEEECCCCCHHHHHHCCCHHHHHHHHHCCCCEEHHHHHHH
NKKTNQQFQLELDLQKAIVHHEFFLLYQPQFTVNTHEIRSMEALIRWNHPQKGIILPLDF
CCCCCCEEEEEEEHHHHHHHHEEEEEECCCEECCHHHHHHHHHHHHCCCCCCCEEEEEEC
IPTAESSGLIVPIGEWVLRETCKQIGAWRTMGLPEIRVACNVASKQLRQRDFPAMVEDLL
CCCCCCCCEEEEHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHH
KEYSVEPHCLELEITENVIIDKEIQRTIKKLKSLGVLIILDDFGTGNSSLNLLKQVAVDS
HHCCCCCCEEEEEECCCEEECHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHHHHHHH
LKIDQSFIQNISKSPGDEAIIDAIIAIAQSMNFNIIAEGVETQNQLKFLKKRRCNDIQGF
HHCCHHHHHHHHCCCCHHHHHHHHHHHHHCCCCEEEECCCCCHHHHHHHHHHCCCHHHHH
LMSKPIPPEEIEKLLQGNRTK
HHCCCCCHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]