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The map label for this gene is htpX [H]

Identifier: 148358399

GI number: 148358399

Start: 273310

End: 274152

Strand: Reverse

Name: htpX [H]

Synonym: LPC_0264

Alternate gene names: 148358399

Gene position: 274152-273310 (Counterclockwise)

Preceding gene: 148358404

Following gene: 148358397

Centisome position: 7.67

GC content: 43.89

Gene sequence:

>843_bases
ATGATAAATAACCTGAAAACTTTTATCTTGCTAGCCTCTCTAACAGCATTGCTAGTTGTTATTGGGGGATTACTTGGCGG
TTCTACAGGAATGCTGGTTGCGTTACTATTCGCAGGAATTATGAATTTTTCGGCTTACTGGTATTCAGATACTCTTGTTT
TGAAAATGTATAATGCTGAGCCTCTTTCTAATAATCACTTTGTTTACCATATTGTTTCAGAGCTTGCTCATAGAGCAGGA
ACCTCAGTACCCAAAGTTTATTTAATTAATAACTCTACTCCGAACGCGTTTGCAACGGGGAGAAATCCAGAGAATGCCAG
TATCGCTGTTACAACAGGATTGTTAGATAGGCTCACTCAAGAAGAAATCACCGGAGTTTTAGCTCATGAACTGGCCCATG
TAATCCACCGCGACACTTTAATTAATGTGGTAAGCGCAACAATAGCAGGGGCGATTAGCGGGATTGCCAATATGTTCATG
TGGCTTTCAATGTTTGGCCACAATTCAAATAATGAAGAAGGTGTCCACCCAGTGGTTGGCATGATCATGATGATAGTAGC
TCCCCTGGCGGCTGGACTAATTCAAATGGCTATATCGCGCTCCAGGGAGTTTGAAGCGGATGCCGGTGGAGCACGAATTT
CCGGGAATCCGCAGTGGCTGGCCAGTGCCTTGTTAAAGCTTGATCAAGCCAACCATGAGCAATACTTTGATGAAGCAGAA
ACTCACCCTGCCACTGCGCACCTGTTTATCATTAATCCATTAAATGGAGAAAAGCTGGCGAACCTCTTTTCAACTCATCC
CTCAACAGCAGAGCGGGTAGCAAGGCTAAGAGCCATGTACTAA

Upstream 100 bases:

>100_bases
CTCTAAAACATGGACATAAACAGAGATAACGCTCCAAGTTGAATTTTTAACATCTGGCCTTATATATGAAATATAGGAAG
AGTCAATGAGGTGATGAGAA

Downstream 100 bases:

>100_bases
TTGAGGTTTCTCTCATTGATTTGGAATAAGCATCGCTTTAATCACAGCCATAAACATAGTACTCCATCCTCGTTATACTC
AGTGCATCTCAATAAAACCA

Product: M48 family peptidase

Products: NA

Alternate protein names: Heat shock protein HtpX [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MINNLKTFILLASLTALLVVIGGLLGGSTGMLVALLFAGIMNFSAYWYSDTLVLKMYNAEPLSNNHFVYHIVSELAHRAG
TSVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQEEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFM
WLSMFGHNSNNEEGVHPVVGMIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
THPATAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY

Sequences:

>Translated_280_residues
MINNLKTFILLASLTALLVVIGGLLGGSTGMLVALLFAGIMNFSAYWYSDTLVLKMYNAEPLSNNHFVYHIVSELAHRAG
TSVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQEEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFM
WLSMFGHNSNNEEGVHPVVGMIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
THPATAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY
>Mature_280_residues
MINNLKTFILLASLTALLVVIGGLLGGSTGMLVALLFAGIMNFSAYWYSDTLVLKMYNAEPLSNNHFVYHIVSELAHRAG
TSVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQEEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFM
WLSMFGHNSNNEEGVHPVVGMIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
THPATAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY

Specific function: Unknown Function. Overexpression Of A Truncated Form Of The Htpx Protein Leads To An Increase In The Degradation Of Abnormal Proteins. [C]

COG id: COG0501

COG function: function code O; Zn-dependent protease with chaperone function

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M48B family [H]

Homologues:

Organism=Escherichia coli, GI1788133, Length=261, Percent_Identity=29.8850574712644, Blast_Score=96, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022919
- InterPro:   IPR001915 [H]

Pfam domain/function: PF01435 Peptidase_M48 [H]

EC number: 3.4.24.- [C]

Molecular weight: Translated: 30293; Mature: 30293

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINNLKTFILLASLTALLVVIGGLLGGSTGMLVALLFAGIMNFSAYWYSDTLVLKMYNAE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCEEEEEEECCC
PLSNNHFVYHIVSELAHRAGTSVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQ
CCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCEEEEHHHHHHHHHH
EEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFMWLSMFGHNSNNEEGVHPVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHC
THPATAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY
CCCCEEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MINNLKTFILLASLTALLVVIGGLLGGSTGMLVALLFAGIMNFSAYWYSDTLVLKMYNAE
CCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHEECCEEEEEEECCC
PLSNNHFVYHIVSELAHRAGTSVPKVYLINNSTPNAFATGRNPENASIAVTTGLLDRLTQ
CCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCEECCCCCCCCEEEEHHHHHHHHHH
EEITGVLAHELAHVIHRDTLINVVSATIAGAISGIANMFMWLSMFGHNSNNEEGVHPVVG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHH
MIMMIVAPLAAGLIQMAISRSREFEADAGGARISGNPQWLASALLKLDQANHEQYFDEAE
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHHHHHHHHHHHHCCHHHHHHHHC
THPATAHLFIINPLNGEKLANLFSTHPSTAERVARLRAMY
CCCCEEEEEEEECCCHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA