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The map label for this gene is supH [H]

Identifier: 148268958

GI number: 148268958

Start: 2697013

End: 2697813

Strand: Reverse

Name: supH [H]

Synonym: SaurJH9_2548

Alternate gene names: 148268958

Gene position: 2697813-2697013 (Counterclockwise)

Preceding gene: 148268961

Following gene: 148268956

Centisome position: 92.81

GC content: 34.71

Gene sequence:

>801_bases
ATGGTTAAGGCTATTGCGGTAGATATGGACGGGACGTTTTTAGATTCGAAAAAGACATACGATAAACCGAGATTTGAAGC
GATTTTTACTGAACTTAGAAATAGAGATATTACATTTATTGCTGCGAGTGGCAATCAATATGCGAAGTTGAAGTCTATTT
TCGGGGATAGAGATATGTATTTTATTTCTGAAAATGGTGCAGTTATTTATAAAGGCAATGAGTTATATAATTATAAAAGC
TTTAATCGTCAGGTGTTTCAACAGGTCGTCGATTACTTAAATATGAACCAAAGTATTGATCAACTCGTCATCTGTGGTTT
GAAAAGCGCGTATATTTTAAAACATACTTCTGAAGCATTTAAAGAAGATACGAGATTTTATTATCATCAGTTAAAAGAAA
TTGACAGTCTACAACAATTACCTGAGGATGATTATGTCAAAATAGCATTTAATATTAATCGTGAGACGCATCCAAATGTT
GACGAAGAAGTAGCAACGCAATTCAGCAATGATATTAAACTTGTCTCAAGTGGGCACGATAGCATTGATATTATTATGCC
AAACATGACTAAAGGGCAGGCATTAAAACGATTGTTAGATAAATGGGAAATGTCTCCTTCAGAGCTCATGGCCTTTGGAG
ATGCGAATAATGATAAAGATATGCTAGCGTTCGCTAAGCATAGTTATGTGATGGAAAATAGTCATGATGAAGAATTGTTC
AATATTGCCTCGGCTGTCGCTCCAAGTAATGATAAGCAGGGTGTTTTAACGATTATCGAACAAGAAGTATTGAACAAGTA
G

Upstream 100 bases:

>100_bases
CAAAATGTGAATATAGTTTCATTGTGGTATGACAAACTTCATTGCTTGTCATGAGATGGATATAATGAAGACGACTAAAA
GAGCAATGAGGAGGATAATC

Downstream 100 bases:

>100_bases
GTAGCACATCATCAATGAAGCGGCTATCATGATACTAAATACATGTTAAATGAAAACTTTGAATACGAATCATCAAACAT
TAATATATCTCAAACAGGTT

Product: Cof-like hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 266; Mature: 266

Protein sequence:

>266_residues
MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMYFISENGAVIYKGNELYNYKS
FNRQVFQQVVDYLNMNQSIDQLVICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
DEEVATQFSNDIKLVSSGHDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
NIASAVAPSNDKQGVLTIIEQEVLNK

Sequences:

>Translated_266_residues
MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMYFISENGAVIYKGNELYNYKS
FNRQVFQQVVDYLNMNQSIDQLVICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
DEEVATQFSNDIKLVSSGHDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
NIASAVAPSNDKQGVLTIIEQEVLNK
>Mature_266_residues
MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMYFISENGAVIYKGNELYNYKS
FNRQVFQQVVDYLNMNQSIDQLVICGLKSAYILKHTSEAFKEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNV
DEEVATQFSNDIKLVSSGHDSIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
NIASAVAPSNDKQGVLTIIEQEVLNK

Specific function: Catalyzes the hydrolysis of sugar phosphate to sugar and inorganic phosphate. Has a wide substrate specificity catalyzing the hydrolysis of fructose-1-P most efficiently, but it remains uncertain if this is the real substrate in vivo [H]

COG id: COG0561

COG function: function code R; Predicted hydrolases of the HAD superfamily

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. Cof family. SupH subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787043, Length=262, Percent_Identity=36.6412213740458, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI87081790, Length=263, Percent_Identity=35.7414448669202, Blast_Score=165, Evalue=3e-42,
Organism=Escherichia coli, GI2367265, Length=282, Percent_Identity=22.6950354609929, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006379
- InterPro:   IPR000150 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.23 [H]

Molecular weight: Translated: 30537; Mature: 30537

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS01229 COF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMY
CCEEEEEECCCCEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEE
FISENGAVIYKGNELYNYKSFNRQVFQQVVDYLNMNQSIDQLVICGLKSAYILKHTSEAF
EEECCCEEEEECCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHH
KEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNVDEEVATQFSNDIKLVSSGHD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCC
SIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
EEEEEECCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHH
NIASAVAPSNDKQGVLTIIEQEVLNK
HHHHHHCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MVKAIAVDMDGTFLDSKKTYDKPRFEAIFTELRNRDITFIAASGNQYAKLKSIFGDRDMY
CCEEEEEECCCCEECCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHHCCCCEE
FISENGAVIYKGNELYNYKSFNRQVFQQVVDYLNMNQSIDQLVICGLKSAYILKHTSEAF
EEECCCEEEEECCEEECHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHH
KEDTRFYYHQLKEIDSLQQLPEDDYVKIAFNINRETHPNVDEEVATQFSNDIKLVSSGHD
HHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCHHHHHHHCCCEEEEECCCC
SIDIIMPNMTKGQALKRLLDKWEMSPSELMAFGDANNDKDMLAFAKHSYVMENSHDEELF
EEEEEECCCCHHHHHHHHHHHHCCCHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHH
NIASAVAPSNDKQGVLTIIEQEVLNK
HHHHHHCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]