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The map label for this gene is gntK [H]

Identifier: 148268939

GI number: 148268939

Start: 2675730

End: 2677283

Strand: Reverse

Name: gntK [H]

Synonym: SaurJH9_2529

Alternate gene names: 148268939

Gene position: 2677283-2675730 (Counterclockwise)

Preceding gene: 148268940

Following gene: 148268938

Centisome position: 92.11

GC content: 37.64

Gene sequence:

>1554_bases
ATGAAATATATGATTGGTGTCGACATTGGAACGACGAGTACCAAGTCAGTCTTATATGATGAAAATGGAGCTTTTATCAT
GAAACATCAAATCGGCTATGATTTACACACACCAAACGTTGATGTCTCAGAAGAAAACCCAGATGAATTATTTGATGCGG
TATTAATGACAATTAAATACATAATGAGGGAATCGAAAGTTAATCAAGATGATATTAAATTTGTGTCATTTAGTGCGCAA
ATGCATAGCTTGATTGCGATGGATCAGCAACATCAAAGATTAACAAATAATATTACTTGGGCAGATAACCGCGCTGCAAA
ATATGCAACAGTAATAAATGAAGTGCATGATGGCAATGCGATTTATCAGCGAACAGGTACGCCTATTCATCCTATGTCGC
CTTTAGTGAAAATTTTTTGGATGAAACATGAATGGCAAGATGTATTTCAACGTACTGCTAAGTTTGCAGATATTAAAACA
TACATTTTCTATCATTTATTTGATACATATATCATTGATTATTCAATGGCTTCCGCAACAGGGATGTTTAATTTAGAAAC
ATTAGATTGGGATGTTGGGGCATTAGAATTGCTTGGTATTTCCAAGGAAATGTTCCCGGAATTAGTGCCAACAACGTACG
TAATGAAAGGCATGAAAGAACGTTATGCAACATTAATGGGGCTTAATGAAGATACACCGTTTGTTATTGGTGCGAGTGAT
GGGGTCCTTTCTAATTTGGGTGTCAATAGTGTTGGTAAAGGAGAAGTTGCTGTCACAATCGGTACATCTGGCGCGATTCG
TACTGTGATAGATAAACCACGTACTGATTACAAAGGTAGAATATTTTGTTATGTCTTAACAGAGGACCACTACGTCATCG
GAGGTCCTGTAAATAATGGTGGTGTCGTATTGAGATGGTTGCGCGACGAGTTGCTAGCGAGTGAAGTCGAAACTGCGAAA
CGTCTCGGTGTTGATCCTTATGATGTCTTAACTCAAATTGCAAAGCGTGTTAAACCAGGTGCAGATGGTTTAATATTCCA
TCCCTATTTAGCTGGAGAACGTGCGCCGCTTTGGAACGCAAATGCAAGAGGTTCATTCTTCGGTTTAACTTTATCTCATA
AAAAAGAACATATGATTCGCGCTGCATTAGAAGGTGTTCTTTACAATTTGTATACCGTCTACCTTGCACTCATTGAAGTA
ATGAATGAAACGCCTAATATGATAAAAGCAACAGGTGGTTTTGCGAAAAGTGAAGTATGGCGTCAAATGATGTCAGATAT
ATTTGACACAGAGTTAGTGGTTCCTGAAAGTTATGAAAGTTCATGCTTAGGTGCCTGCGTGCTTGGACTTAAAGCTGTAG
GTGACATTGAAGATTTTTCAATCGTTTCATCGATGGTCGGTGCTACAAATAATCATACGCCGTTTGAAGAAAATGTCGCT
GTTTACCAAGAGCTCGTATCCATTTTTATCAATTTAAGTCGTTCTTTAACAGAGAATTATGAACAAATTGCAGATTTTCA
ACGCCAACATATGGCTGAAAATAAAACACAATAA

Upstream 100 bases:

>100_bases
GTCAAATTTTGAAGGAAGCGTTTCATTTAAATTTTGACGATGTTGGTAAAGATATTGAAGGATTTTGGTTGAATTAAAAT
GAAAGAAAGAAGGATTTATC

Downstream 100 bases:

>100_bases
ATACGTCACTCAAGCATCTTAGATAAAGTTGTTGTGCCATGACTACTATATATTATCTGGAATACGTGCGCGACGACGGT
GTTACATTCTATTGAAAAGA

Product: gluconate kinase

Products: NA

Alternate protein names: Gluconate kinase [H]

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKT
YIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPNMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVA
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ

Sequences:

>Translated_517_residues
MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKT
YIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPNMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVA
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
>Mature_517_residues
MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKYIMRESKVNQDDIKFVSFSAQ
MHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNAIYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKT
YIFYHLFDTYIIDYSMASATGMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNGGVVLRWLRDELLASEVETAK
RLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNANARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEV
MNETPNMIKATGGFAKSEVWRQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVA
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ

Specific function: Unknown

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family [H]

Homologues:

Organism=Homo sapiens, GI42794763, Length=459, Percent_Identity=24.8366013071895, Blast_Score=122, Evalue=1e-27,
Organism=Homo sapiens, GI4504007, Length=459, Percent_Identity=24.8366013071895, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI189409120, Length=459, Percent_Identity=24.8366013071895, Blast_Score=117, Evalue=4e-26,
Organism=Homo sapiens, GI41393575, Length=452, Percent_Identity=23.6725663716814, Blast_Score=107, Evalue=4e-23,
Organism=Homo sapiens, GI88196792, Length=489, Percent_Identity=23.1083844580777, Blast_Score=100, Evalue=6e-21,
Organism=Escherichia coli, GI1789987, Length=502, Percent_Identity=25.6972111553785, Blast_Score=152, Evalue=4e-38,
Organism=Escherichia coli, GI1790361, Length=465, Percent_Identity=26.2365591397849, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1787789, Length=503, Percent_Identity=24.8508946322068, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1790005, Length=517, Percent_Identity=22.8239845261122, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1789168, Length=461, Percent_Identity=21.0412147505423, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1789138, Length=518, Percent_Identity=22.972972972973, Blast_Score=91, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17535599, Length=465, Percent_Identity=24.3010752688172, Blast_Score=117, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6321755, Length=360, Percent_Identity=24.4444444444444, Blast_Score=85, Evalue=3e-17,
Organism=Drosophila melanogaster, GI17864214, Length=489, Percent_Identity=24.7443762781186, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24655555, Length=447, Percent_Identity=25.2796420581655, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655560, Length=447, Percent_Identity=25.2796420581655, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655570, Length=447, Percent_Identity=25.2796420581655, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655574, Length=447, Percent_Identity=25.2796420581655, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24655565, Length=447, Percent_Identity=25.2796420581655, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24654573, Length=413, Percent_Identity=24.9394673123487, Blast_Score=113, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24656367, Length=540, Percent_Identity=21.8518518518519, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI21357867, Length=553, Percent_Identity=22.4231464737794, Blast_Score=110, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24656372, Length=389, Percent_Identity=23.1362467866324, Blast_Score=90, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR006002 [H]

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N [H]

EC number: =2.7.1.12 [H]

Molecular weight: Translated: 58078; Mature: 58078

Theoretical pI: Translated: 4.98; Mature: 4.98

Prosite motif: PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKY
CCEEEEEECCCCCCCEEEEECCCCEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHH
IMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNA
HHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASAT
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
CCEEEEEECCCCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNG
CHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCC
GVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNA
CEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPNMIKATGGFAKSEVW
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHH
RQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVA
HHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKYMIGVDIGTTSTKSVLYDENGAFIMKHQIGYDLHTPNVDVSEENPDELFDAVLMTIKY
CCEEEEEECCCCCCCEEEEECCCCEEEEEECCCEECCCCCCCCCCCHHHHHHHHHHHHHH
IMRESKVNQDDIKFVSFSAQMHSLIAMDQQHQRLTNNITWADNRAAKYATVINEVHDGNA
HHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCE
IYQRTGTPIHPMSPLVKIFWMKHEWQDVFQRTAKFADIKTYIFYHLFDTYIIDYSMASAT
EEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
GMFNLETLDWDVGALELLGISKEMFPELVPTTYVMKGMKERYATLMGLNEDTPFVIGASD
CCEEEEEECCCCCHHHHCCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCC
GVLSNLGVNSVGKGEVAVTIGTSGAIRTVIDKPRTDYKGRIFCYVLTEDHYVIGGPVNNG
CHHHHCCCCCCCCCCEEEEECCCCCHHHHHCCCCCCCCCEEEEEEEECCCEEEECCCCCC
GVVLRWLRDELLASEVETAKRLGVDPYDVLTQIAKRVKPGADGLIFHPYLAGERAPLWNA
CEEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCEEECCCCCCCCCCCCCC
NARGSFFGLTLSHKKEHMIRAALEGVLYNLYTVYLALIEVMNETPNMIKATGGFAKSEVW
CCCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHH
RQMMSDIFDTELVVPESYESSCLGACVLGLKAVGDIEDFSIVSSMVGATNNHTPFEENVA
HHHHHHHCCCEEECCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCHHHHH
VYQELVSIFINLSRSLTENYEQIADFQRQHMAENKTQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3020045; 7584049; 9384377 [H]