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The map label for this gene is tcyB [H]

Identifier: 148268848

GI number: 148268848

Start: 2571304

End: 2572023

Strand: Reverse

Name: tcyB [H]

Synonym: SaurJH9_2438

Alternate gene names: 148268848

Gene position: 2572023-2571304 (Counterclockwise)

Preceding gene: 148268849

Following gene: 148268847

Centisome position: 88.49

GC content: 33.61

Gene sequence:

>720_bases
ATGTTTCTAAATCTAAATAGCGAACAACAACATGCGCTAGATGCTGCAAAACAAGCTTTCGGACCTATGCTAGAAGGTTT
GGTCAAATATTCAATTCCTATTACATTAGTTACATTTGTTTTAGGATTGATTATTGCATTATTTACAGCATTAATGCGAA
TTTCAACGAGTAAAATTTTAAGAAGTATTTCACGTGTCTATGTATCTATTATTCGAGGAACACCAATGATAGTACAACTA
TTTATCATATTTTATGGTATTCCAGAATTAGGTAGATTATTAACAAATGACGCTGACAACCAATGGACATTGGCACCTGT
AGTGGCTGCTATTATTGGTTTATCATTAAATGTAGGTGCGTATGCTTCGGAAATTATTCGTGGCGGTATTATTTCTATAC
CGAAAGGACAAACAGAAGCTGCATATTCCATCGGTATGACGTATGGTCAAACGATACAACGTATCATTTTACCGCAGGCA
ATTCGAGTGTCGATTCCTGCACTAGGTAATACATTTTTAAGTTTAATCAAAGATACATCATTATTAGGATTTATTTTAGT
GGCTGAAATGTTTAGAAAAGCTCAAGAAGTTGCGTCTACAACATATGAATATTTAACAATTTATGTGTTAGTTGCGCTAA
TGTACTGGGTGGTATGCTTTATTATTTCAATTATCCAAGGTATCTATGAATCTTATATTGAAAGAGGGTATCGCTCATGA

Upstream 100 bases:

>100_bases
AAAGCAGATGATGAAACAGTTCAAAAATTCAATGATGGCTTGAAAAAAATCGAGGAAAACGGTGAATTAGCTAAAATAGG
TAAGAAATGGTTTGGTCAAG

Downstream 100 bases:

>100_bases
TTCAATTGAACAATATCCATAAATCATTTAATGATGTTGAAGTCATCAAAGGTATTGATTTATCTGTTGAACAAGGTGAG
GTTGTAACCTTAATCGGTCG

Product: polar amino acid ABC transporter, inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 239; Mature: 239

Protein sequence:

>239_residues
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQL
FIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQA
IRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS

Sequences:

>Translated_239_residues
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQL
FIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQA
IRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
>Mature_239_residues
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKILRSISRVYVSIIRGTPMIVQL
FIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGAYASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQA
IRVSIPALGNTFLSLIKDTSLLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS

Specific function: Part of the ABC transporter complex tcyABC involved in L-cystine import. Probably responsible for the translocation of the substrate across the membrane (Probable) [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=218, Percent_Identity=44.4954128440367, Blast_Score=186, Evalue=9e-49,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=34.8039215686275, Blast_Score=124, Evalue=4e-30,
Organism=Escherichia coli, GI87082239, Length=194, Percent_Identity=34.5360824742268, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788646, Length=199, Percent_Identity=32.1608040201005, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1786873, Length=214, Percent_Identity=31.7757009345794, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788645, Length=187, Percent_Identity=28.8770053475936, Blast_Score=100, Evalue=9e-23,
Organism=Escherichia coli, GI1787087, Length=206, Percent_Identity=27.6699029126214, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1787086, Length=182, Percent_Identity=31.8681318681319, Blast_Score=87, Evalue=9e-19,
Organism=Escherichia coli, GI1786874, Length=184, Percent_Identity=25.5434782608696, Blast_Score=80, Evalue=8e-17,
Organism=Escherichia coli, GI48994930, Length=213, Percent_Identity=28.6384976525822, Blast_Score=75, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 26443; Mature: 26443

Theoretical pI: Translated: 9.14; Mature: 9.14

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKIL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGA
HHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHH
YASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTS
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MFLNLNSEQQHALDAAKQAFGPMLEGLVKYSIPITLVTFVLGLIIALFTALMRISTSKIL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RSISRVYVSIIRGTPMIVQLFIIFYGIPELGRLLTNDADNQWTLAPVVAAIIGLSLNVGA
HHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHH
YASEIIRGGIISIPKGQTEAAYSIGMTYGQTIQRIILPQAIRVSIPALGNTFLSLIKDTS
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHH
LLGFILVAEMFRKAQEVASTTYEYLTIYVLVALMYWVVCFIISIIQGIYESYIERGYRS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7551042; 8969502; 9384377 [H]