Click here to switch to the map view.

The map label for this gene is ywlC [H]

Identifier: 148268567

GI number: 148268567

Start: 2272809

End: 2273882

Strand: Reverse

Name: ywlC [H]

Synonym: SaurJH9_2152

Alternate gene names: 148268567

Gene position: 2273882-2272809 (Counterclockwise)

Preceding gene: 148268568

Following gene: 148268566

Centisome position: 78.23

GC content: 35.1

Gene sequence:

>1074_bases
ATGATAAATAAGAAAGGCGTGATTAAGTTGGATACTAAAATTTGGGATGTTAGAGAATATAATGAAGATTTACAGCAATA
TCCTAAAATTAATGAAATAAAAGACATTGTTTTAAACGGTGGTTTAATAGGTTTACCAACTGAAACAGTTTATGGACTTG
CAGCAAATGCGACAGATGAAGAAGCTGTAGCTAAAATATATGAAGCTAAAGGCCGTCCATCTGACAATCCGCTTATTGTT
CATATACACAGTAAAGTTCAATTAAAAGATTTTACATATACTTTGGATCCACGCGTAGAAAAGTTAATGCAGGCATTCTG
GCCGGGCCCTATTTCGTTTATATTGCCGCTAAAGCCAGGCTATCTATGTCGAAAAGTTTCTGGAGGTTTATCATCAGTTG
CTGTTAGAATGCCAAGCCATTCTGTAGGTAGACAATTATTACAAATCATAAATGAACCTCTAGCTGCTCCAAGTGCTAAT
TTAAGTGGTAGACCTTCACCAACAACTTTCAATCATGTATATCAAGATTTGAATGCCCGTATAGATGGTATTGTTCAAGC
TGAACAAAGTGAAGAAGGATTAGAAAGTACGGTTTTAGATTGCACATCTTTTCCTTATAAAATTGCAAGACCTGGTTCTA
TAACAGCAGCAATGATTACAGAAATACTTCCGAATAGTATCGCCCATGCTGATTATAATGATACTGAACAGCCAATTGCA
CCAGGTATGAAGTATAAGCATTACTCACCCAATACACCACTTACAATTATTACAGATATTGAGAGCAAAATTGGAAATGA
CGGTAAAGATTGGTCTTCTATAGCTTTTATTGTGCCGAGTAATAAGGTGGCGTTTATACCAAGTGAAGCGCAATTCATTC
AATTATGTCAGGATGACAATGATGTTAAACAAGCAAGTCATAATCTTTATGATGTGTTACATTCACTTGATGAAAATGAA
AATATTTCAGCGGCGTATATATACGGCTTTGAGCTGAATGATAATACAGAAGCAATTATGAATCGCATGTTAAAAGCTGC
AGGTAATCACATTATTAAAGGATGTGAACTATGA

Upstream 100 bases:

>100_bases
AAGATATAAATGGCCACGATCGAATCGTCTCATTTAAATGGTAATTAGAAGTTATGCCTTTGCTATGATTAGTTAAGTGC
ATAGCTTTTTGCTTTATATT

Downstream 100 bases:

>100_bases
AGATTTTATTCGTTTGTACAGGTAACACATGTCGTAGCCCATTAGCGGAAAGTATTGCAAAAGAGGTTATGCCAAATCAT
CAATTTGAATCAAGAGGTAT

Product: Sua5/YciO/YrdC/YwlC family protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIV
HIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSAN
LSGRPSPTTFNHVYQDLNARIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIA
PGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENE
NISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

Sequences:

>Translated_357_residues
MINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIV
HIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSAN
LSGRPSPTTFNHVYQDLNARIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIA
PGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENE
NISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL
>Mature_357_residues
MINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDEEAVAKIYEAKGRPSDNPLIV
HIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPGYLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSAN
LSGRPSPTTFNHVYQDLNARIDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIA
PGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDNDVKQASHNLYDVLHSLDENE
NISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Homo sapiens, GI58761510, Length=206, Percent_Identity=31.0679611650485, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI2367210, Length=162, Percent_Identity=34.5679012345679, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17537239, Length=186, Percent_Identity=30.6451612903226, Blast_Score=72, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6321269, Length=378, Percent_Identity=31.2169312169312, Blast_Score=162, Evalue=6e-41,
Organism=Drosophila melanogaster, GI78707274, Length=184, Percent_Identity=32.0652173913043, Blast_Score=87, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 39480; Mature: 39480

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDE
CCCCCCEEEECCEEEHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCHHHHEEECCCCCH
EAVAKIYEAKGRPSDNPLIVHIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPG
HHHHHHHHHCCCCCCCCEEEEEECEEEEEEEEEECCHHHHHHHHHHCCCCEEEEEECCCC
YLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNAR
HHHHHHCCCHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIA
HHHEEECCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDN
CCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCEEEEEEECCEEEEECCHHHHHHHHCCCC
DVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCHHHCCCCC
>Mature Secondary Structure
MINKKGVIKLDTKIWDVREYNEDLQQYPKINEIKDIVLNGGLIGLPTETVYGLAANATDE
CCCCCCEEEECCEEEHHHHHHHHHHHCCCHHHHHHHHHCCCEEECCCHHHHEEECCCCCH
EAVAKIYEAKGRPSDNPLIVHIHSKVQLKDFTYTLDPRVEKLMQAFWPGPISFILPLKPG
HHHHHHHHHCCCCCCCCEEEEEECEEEEEEEEEECCHHHHHHHHHHCCCCEEEEEECCCC
YLCRKVSGGLSSVAVRMPSHSVGRQLLQIINEPLAAPSANLSGRPSPTTFNHVYQDLNAR
HHHHHHCCCHHHEEEECCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
IDGIVQAEQSEEGLESTVLDCTSFPYKIARPGSITAAMITEILPNSIAHADYNDTEQPIA
HHHEEECCHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCC
PGMKYKHYSPNTPLTIITDIESKIGNDGKDWSSIAFIVPSNKVAFIPSEAQFIQLCQDDN
CCCCCCCCCCCCCEEEEEECHHHCCCCCCCCCEEEEEEECCEEEEECCHHHHHHHHCCCC
DVKQASHNLYDVLHSLDENENISAAYIYGFELNDNTEAIMNRMLKAAGNHIIKGCEL
HHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCHHHHHHHHHHHCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]