Definition Staphylococcus aureus subsp. aureus JH9, complete genome.
Accession NC_009487
Length 2,906,700

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The map label for this gene is natA [H]

Identifier: 148268407

GI number: 148268407

Start: 2122851

End: 2123747

Strand: Reverse

Name: natA [H]

Synonym: SaurJH9_1990

Alternate gene names: 148268407

Gene position: 2123747-2122851 (Counterclockwise)

Preceding gene: 148268408

Following gene: 148268406

Centisome position: 73.06

GC content: 31.1

Gene sequence:

>897_bases
ATGAATGCCATAGAATTAAGTAATGTTAATTATTCAAGTGATCAGTTTAATTTAAAGAATATCTCTTTCAAAGTTCCTCA
AGGATTCGTCACTGGTTTTATTGGTAGAAATGGCGCTGGTAAAACCACAATAATAAGGTTAATTATGGATTTGTATCAAC
CACAAACTGGTGTTATTAGAGTATTAGAAGAGGATATGGCTCTCAATCCGATAGAGTTAAAGAATAGTATTGGGTTTGTT
TACTCTGAAAATTATTTTAATGAGAGATGGACTACGAAGCAACTTGAAAAAATGATTGCCCCTTTTTATCGTAAATGGGA
CCATCAAGTATTTGAATTTTATCTTGAAAAGTTCGATTTACCAATCAATAAATCAATAAAAACATTTTCGACTGGGATGA
AAATGAAATTATCACTAGCAGTTGCATTTTCACATCATGCTGAATTGTATATTTTTGATGAGCCTACTTCAGGTCTTGAT
CCCTTAGCTAGAAATGAGCTATTGGAGATAATTCAGCAAGAATTAATTGATGAAAATAAAACAATATTCATGTCGACACA
CATTATCTCAGATTTAGAAAAAATAGCTGATTATATCATTCACTTAAGTGACGGTGAAGTTATCTTAAATGGTTCAAAAG
AACAACTGTTACAAAGATATCAAGTTGTGAGTGGTGCAACTGAGGACCTTGATGATGAATTAGCATCTCTACTTATTTAT
GAAGAACATAAGCGTACGGGATTTATAGGATTAACAGAACATGCGCAAGTATTTAAAGAAATTTTAGGTCATAAAGTGAA
TATCACTACACCTTCTATTGAGAACTTAATGGTTTATCTTGAAAAGAGAAAACCTAAATATCATGAAAACATCAAATTGA
TGGAAGAAGGTTTTTAA

Upstream 100 bases:

>100_bases
AAAATTTGGTTAAAGAATTGGTTAATGAAGCGCAAGCCATCGAAATGTCACTTGAGGAACTTCAAGATATTTTAACGTTC
ATTTATGAGGAGGAATCATC

Downstream 100 bases:

>100_bases
ATGAAGGCATTGTTAATTAGGAATTTTAAATTACGACGATATACACTTATCATCTATGTTCTATTATTAACCTTATATCC
TTTTTATATAATGCTTGACT

Product: ABC transporter

Products: NA

Alternate protein names: Na(+) ABC transporter [H]

Number of amino acids: Translated: 298; Mature: 298

Protein sequence:

>298_residues
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIRVLEEDMALNPIELKNSIGFV
YSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLD
PLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIY
EEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF

Sequences:

>Translated_298_residues
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIRVLEEDMALNPIELKNSIGFV
YSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLD
PLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIY
EEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF
>Mature_298_residues
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIRVLEEDMALNPIELKNSIGFV
YSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLD
PLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIY
EEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF

Specific function: Involved in ATP-dependent electrogenic sodium extrusion [H]

COG id: COG1131

COG function: function code V; ABC-type multidrug transport system, ATPase component

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI45446740, Length=219, Percent_Identity=28.310502283105, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI47078218, Length=219, Percent_Identity=28.310502283105, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI31657092, Length=198, Percent_Identity=29.2929292929293, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI105990541, Length=198, Percent_Identity=30.3030303030303, Blast_Score=88, Evalue=1e-17,
Organism=Homo sapiens, GI150417984, Length=222, Percent_Identity=28.3783783783784, Blast_Score=87, Evalue=2e-17,
Organism=Homo sapiens, GI116734710, Length=214, Percent_Identity=24.2990654205607, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI153792144, Length=211, Percent_Identity=27.4881516587678, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI27881501, Length=200, Percent_Identity=28.5, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI30795238, Length=200, Percent_Identity=28.5, Blast_Score=86, Evalue=4e-17,
Organism=Homo sapiens, GI27477115, Length=207, Percent_Identity=25.6038647342995, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI21536376, Length=196, Percent_Identity=30.1020408163265, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI6005701, Length=207, Percent_Identity=26.0869565217391, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI27436953, Length=207, Percent_Identity=25.1207729468599, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI255708477, Length=249, Percent_Identity=24.4979919678715, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI27262624, Length=211, Percent_Identity=23.696682464455, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI27262626, Length=211, Percent_Identity=23.696682464455, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI156105685, Length=215, Percent_Identity=26.5116279069767, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI9961252, Length=221, Percent_Identity=25.7918552036199, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI4505771, Length=221, Percent_Identity=25.7918552036199, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI9961250, Length=221, Percent_Identity=25.7918552036199, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI42741659, Length=235, Percent_Identity=24.6808510638298, Blast_Score=72, Evalue=6e-13,
Organism=Homo sapiens, GI9955963, Length=250, Percent_Identity=26.8, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI90421313, Length=207, Percent_Identity=29.4685990338164, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI42490749, Length=217, Percent_Identity=25.8064516129032, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI157502201, Length=208, Percent_Identity=27.8846153846154, Blast_Score=69, Evalue=7e-12,
Organism=Homo sapiens, GI157502203, Length=208, Percent_Identity=27.8846153846154, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI9665248, Length=218, Percent_Identity=23.394495412844, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI148612844, Length=219, Percent_Identity=25.5707762557078, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI1786319, Length=226, Percent_Identity=30.9734513274336, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI48994943, Length=224, Percent_Identity=28.125, Blast_Score=95, Evalue=5e-21,
Organism=Escherichia coli, GI1788225, Length=236, Percent_Identity=31.3559322033898, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI87081782, Length=210, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1786345, Length=237, Percent_Identity=23.6286919831224, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787029, Length=228, Percent_Identity=27.6315789473684, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787112, Length=231, Percent_Identity=27.7056277056277, Blast_Score=75, Evalue=4e-15,
Organism=Escherichia coli, GI1789672, Length=223, Percent_Identity=28.6995515695067, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788450, Length=231, Percent_Identity=24.6753246753247, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1787143, Length=243, Percent_Identity=26.7489711934156, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787089, Length=226, Percent_Identity=25.2212389380531, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI87081709, Length=227, Percent_Identity=25.9911894273128, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786253, Length=201, Percent_Identity=23.3830845771144, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1788472, Length=219, Percent_Identity=26.4840182648402, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI48995001, Length=209, Percent_Identity=26.7942583732057, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789864, Length=229, Percent_Identity=24.4541484716157, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786698, Length=209, Percent_Identity=26.7942583732057, Blast_Score=66, Evalue=3e-12,
Organism=Escherichia coli, GI1788210, Length=201, Percent_Identity=25.3731343283582, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87082268, Length=225, Percent_Identity=26.2222222222222, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1788644, Length=88, Percent_Identity=37.5, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1788540, Length=194, Percent_Identity=24.2268041237113, Blast_Score=61, Evalue=7e-11,
Organism=Escherichia coli, GI1790525, Length=212, Percent_Identity=25, Blast_Score=61, Evalue=9e-11,
Organism=Caenorhabditis elegans, GI71983516, Length=205, Percent_Identity=28.2926829268293, Blast_Score=98, Evalue=6e-21,
Organism=Caenorhabditis elegans, GI71983510, Length=205, Percent_Identity=28.2926829268293, Blast_Score=98, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI71983523, Length=205, Percent_Identity=28.2926829268293, Blast_Score=97, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI115533608, Length=191, Percent_Identity=28.2722513089005, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17510237, Length=225, Percent_Identity=28, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17565586, Length=212, Percent_Identity=29.7169811320755, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI193208177, Length=214, Percent_Identity=28.0373831775701, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6323959, Length=245, Percent_Identity=28.9795918367347, Blast_Score=80, Evalue=5e-16,
Organism=Saccharomyces cerevisiae, GI6324985, Length=251, Percent_Identity=26.2948207171315, Blast_Score=67, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6321081, Length=247, Percent_Identity=23.8866396761134, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24643674, Length=217, Percent_Identity=29.0322580645161, Blast_Score=95, Evalue=4e-20,
Organism=Drosophila melanogaster, GI24666092, Length=231, Percent_Identity=28.1385281385281, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24648314, Length=209, Percent_Identity=28.7081339712919, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI221512771, Length=209, Percent_Identity=28.2296650717703, Blast_Score=87, Evalue=2e-17,
Organism=Drosophila melanogaster, GI85725262, Length=263, Percent_Identity=26.2357414448669, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573571, Length=207, Percent_Identity=27.0531400966184, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28573573, Length=207, Percent_Identity=27.0531400966184, Blast_Score=82, Evalue=5e-16,
Organism=Drosophila melanogaster, GI28574150, Length=210, Percent_Identity=30.4761904761905, Blast_Score=82, Evalue=6e-16,
Organism=Drosophila melanogaster, GI116007328, Length=210, Percent_Identity=30.4761904761905, Blast_Score=81, Evalue=8e-16,
Organism=Drosophila melanogaster, GI116007184, Length=210, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI221500365, Length=210, Percent_Identity=26.1904761904762, Blast_Score=80, Evalue=1e-15,
Organism=Drosophila melanogaster, GI23397593, Length=221, Percent_Identity=28.0542986425339, Blast_Score=78, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24650853, Length=212, Percent_Identity=27.8301886792453, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24650855, Length=212, Percent_Identity=27.8301886792453, Blast_Score=78, Evalue=8e-15,
Organism=Drosophila melanogaster, GI281363262, Length=216, Percent_Identity=27.7777777777778, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24653245, Length=216, Percent_Identity=27.7777777777778, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281362751, Length=212, Percent_Identity=27.8301886792453, Blast_Score=76, Evalue=3e-14,
Organism=Drosophila melanogaster, GI21357907, Length=230, Percent_Identity=27.3913043478261, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24582014, Length=242, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24582012, Length=242, Percent_Identity=25.6198347107438, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 34440; Mature: 34440

Theoretical pI: Translated: 5.12; Mature: 5.12

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIR
CCCEEECCCCCCCCCEEEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
VLEEDMALNPIELKNSIGFVYSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDL
HHHHHCCCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLDPLARNELLEIIQQELIDENK
CCCCCHHHHHCCCEEEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
TIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIY
EEEEEHHHHHHHHHHHHHHEECCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF
HHCCCCCEEEEHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCHHCCCHHHCCCC
>Mature Secondary Structure
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIR
CCCEEECCCCCCCCCEEEEEEEEECCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCHHHHH
VLEEDMALNPIELKNSIGFVYSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDL
HHHHHCCCCCCHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLDPLARNELLEIIQQELIDENK
CCCCCHHHHHCCCEEEEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCC
TIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIY
EEEEEHHHHHHHHHHHHHHEECCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHH
EEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF
HHCCCCCEEEEHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHCCCCHHCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9106203; 9274031; 9384377 [H]