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The map label for this gene is sdcS [H]

Identifier: 148268390

GI number: 148268390

Start: 2107146

End: 2108708

Strand: Reverse

Name: sdcS [H]

Synonym: SaurJH9_1972

Alternate gene names: 148268390

Gene position: 2108708-2107146 (Counterclockwise)

Preceding gene: 148268391

Following gene: 148268387

Centisome position: 72.55

GC content: 34.36

Gene sequence:

>1563_bases
ATGGCTTATTTCAATCAACATCAATCAATGATATCGAAAAGGTATTTAACATTCTTTTCAAAATCAAAGAAAAAGAAACC
GTTTAGTGCGGGACAACTTATTGGACTAATATTAGGTCCATTACTTTTCCTATTAACATTATTGTTCTTTCATCCACAAG
ACTTACCTTGGAAAGGCGTATATGTCTTAGCGATTACTTTATGGATTGCGACTTGGTGGATTACTGAAGCAATTCCTATT
GCAGCAACGAGCTTATTACCAATTGTGTTATTACCATTAGGTCACATACTTACACCAGAACAAGTATCATCCGAATATGG
CAATGATATTATCTTTTTGTTTTTAGGTGGATTTATTTTGGCAATTGCAATGGAAAGATGGAATTTACATACGAGAGTAG
CTTTGACTATTATTAATTTAATTGGTGCAAGCACTTCAAAAATATTACTTGGATTCATGGTGGCAACAGGATTCTTATCT
ATGTTTGTATCGAACACTGCAGCTGTAATGATTATGATTCCGATTGGTTTAGCAATTATTAAGGAAGCACATGATTTACA
AGAAGCCAATACGAATCAAACAAGTATTCAAAAGTTTGAAAAATCTCTAGTTTTAGCAATTGGCTATGCAGGTACGATTG
GTGGCTTGGGTACATTAATCGGAACCCCGCCATTAATTATTTTAAAAGGACAATACATGCAACATTTTGGACATGAAATT
AGTTTTGCTAAATGGATGATTGTAGGGATTCCAACGGTCATTGTTTTGTTAGGTATTACTTGGCTCTATTTAAGATATGT
TGCGTTTAGACATGATTTGAAATATTTACCTGGTGGTCAGACGTTAATTAAACAAAAGTTAGACGAGCTTGGCAAAATGA
AGTATGAAGAAAAGGTAGTACAAACTATCTTTGTACTTGCCAGCTTATTATGGATTACAAGAGAGTTTCTTCTGAAAAAA
TGGGAAGTTACGTCATCTGTTGCAGATGGTACGATTGCTATTTTTATATCAATATTATTATTTATTATTCCAGCTAAAAA
TACTGAAAAACATCGCCGTATCATTGACTGGGAAGTTGCAAAAGAGCTCCCTTGGGGTGTATTAATTTTATTTGGTGGCG
GTTTAGCATTAGCGAAAGGTATTTCTGAAAGTGGTTTAGCAAAATGGTTAGGCGAACAGTTGAAATCATTAAATGGTGTT
AGTCCGATTCTTATTGTAATTGTCATAACAATCTTTGTCTTATTTTTAACTGAAGTGACATCTAATACTGCAACTGCAAC
GATGATTTTACCGATTTTAGCAACGTTGTCTGTTGCTGTTGGAGTGCATCCATTACTACTTATGGCACCTGCAGCTATGG
CGGCTAACTGTGCATACATGTTACCAGTAGGGACACCACCGAATGCAATTATCTTTGGTTCAGGTAAAATATCTATCAAA
CAAATGGCATCAGTAGGATTCTGGGTAAACTTAATCAGTGCAATAATTATTATTTTAGTCGTGTATTATGTAATGCCTAT
AGTTTTAGGTATTGATATAAATCAACCACTGCCATTGAAATAG

Upstream 100 bases:

>100_bases
GGGTATTTTGACGGTAATGATAATACAAGATAGACAACTTTCTATACTCTAATATAGTGAGTTGAAGTAGCTTGTCATAA
TCATCATGAGGGGGAAATTT

Downstream 100 bases:

>100_bases
TAATTGCAGATTAGAACGAAAAATAAAAGGTTACATTAGCAATTGCTTGAACGAGTGGTAATGAAACGTATACCGCAGCA
TCGTGTAAAAACAATACAAA

Product: anion transporter

Products: tartrate [Cytoplasm]; succinate [Periplasm] [C]

Alternate protein names: Na(+)/dicarboxylate symporter [H]

Number of amino acids: Translated: 520; Mature: 519

Protein sequence:

>520_residues
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPI
AATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLS
MFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKK
WEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGV
SPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK

Sequences:

>Translated_520_residues
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPI
AATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLS
MFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKK
WEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGV
SPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
>Mature_519_residues
AYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIA
ATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSM
FVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEIS
FAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKW
EVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVS
PILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQ
MASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK

Specific function: Mediates the transport of the dicarboxylates fumarate, malate, and succinate across the cytoplasmic membrane via a Na(+)- electrochemical gradient [H]

COG id: COG0471

COG function: function code P; Di- and tricarboxylate transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SLC13A transporter (TC 2.A.47) family. NADC subfamily [H]

Homologues:

Organism=Homo sapiens, GI29171306, Length=514, Percent_Identity=35.2140077821012, Blast_Score=303, Evalue=4e-82,
Organism=Homo sapiens, GI31377715, Length=561, Percent_Identity=33.6898395721925, Blast_Score=283, Evalue=2e-76,
Organism=Homo sapiens, GI4506979, Length=522, Percent_Identity=35.823754789272, Blast_Score=281, Evalue=1e-75,
Organism=Homo sapiens, GI58761541, Length=517, Percent_Identity=33.4622823984526, Blast_Score=275, Evalue=9e-74,
Organism=Homo sapiens, GI301069349, Length=500, Percent_Identity=33.2, Blast_Score=263, Evalue=3e-70,
Organism=Homo sapiens, GI301069346, Length=517, Percent_Identity=35.0096711798839, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI225637549, Length=572, Percent_Identity=33.2167832167832, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI225637552, Length=480, Percent_Identity=35.8333333333333, Blast_Score=252, Evalue=7e-67,
Organism=Homo sapiens, GI19923838, Length=533, Percent_Identity=30.3939962476548, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI219802232, Length=455, Percent_Identity=34.7252747252747, Blast_Score=248, Evalue=1e-65,
Organism=Homo sapiens, GI301069353, Length=466, Percent_Identity=31.7596566523605, Blast_Score=228, Evalue=1e-59,
Organism=Homo sapiens, GI31795546, Length=347, Percent_Identity=33.4293948126801, Blast_Score=190, Evalue=3e-48,
Organism=Escherichia coli, GI1789444, Length=417, Percent_Identity=24.220623501199, Blast_Score=73, Evalue=4e-14,
Organism=Escherichia coli, GI1786829, Length=391, Percent_Identity=21.4833759590793, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1786986, Length=434, Percent_Identity=26.9585253456221, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71988385, Length=501, Percent_Identity=34.9301397205589, Blast_Score=280, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI32565804, Length=463, Percent_Identity=34.7732181425486, Blast_Score=264, Evalue=9e-71,
Organism=Caenorhabditis elegans, GI71989118, Length=528, Percent_Identity=33.7121212121212, Blast_Score=253, Evalue=1e-67,
Organism=Caenorhabditis elegans, GI17551790, Length=497, Percent_Identity=28.5714285714286, Blast_Score=221, Evalue=8e-58,
Organism=Caenorhabditis elegans, GI32564681, Length=512, Percent_Identity=28.515625, Blast_Score=216, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6324340, Length=478, Percent_Identity=23.2217573221757, Blast_Score=89, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6322263, Length=477, Percent_Identity=24.3186582809224, Blast_Score=85, Evalue=4e-17,
Organism=Saccharomyces cerevisiae, GI6319885, Length=477, Percent_Identity=23.6897274633124, Blast_Score=77, Evalue=5e-15,
Organism=Drosophila melanogaster, GI281362116, Length=486, Percent_Identity=34.156378600823, Blast_Score=233, Evalue=2e-61,
Organism=Drosophila melanogaster, GI281362114, Length=486, Percent_Identity=33.9506172839506, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI281362112, Length=486, Percent_Identity=33.9506172839506, Blast_Score=226, Evalue=2e-59,
Organism=Drosophila melanogaster, GI45551633, Length=522, Percent_Identity=30.4597701149425, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI281366409, Length=522, Percent_Identity=30.2681992337165, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI17737623, Length=522, Percent_Identity=30.2681992337165, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI24666468, Length=522, Percent_Identity=30.2681992337165, Blast_Score=225, Evalue=5e-59,
Organism=Drosophila melanogaster, GI78706796, Length=467, Percent_Identity=30.6209850107066, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI78706798, Length=467, Percent_Identity=30.6209850107066, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI281364821, Length=452, Percent_Identity=21.6814159292035, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001898 [H]

Pfam domain/function: PF00939 Na_sulph_symp [H]

EC number: NA

Molecular weight: Translated: 57173; Mature: 57041

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGV
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
YVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEHHHHHHHHH
AIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAII
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEHHHHHHHHHH
KEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
HHHHHHHHCCCCHHHHHHHHHHHEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHCCCCH
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVT
HHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCEEHH
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
AYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGV
CCHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
YVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCEEHHHHHHHHH
AIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAII
HHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCHHHEEHHHHHHHHHH
KEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEI
HHHHHHHHCCCCHHHHHHHHHHHEEEEECCHHHHHHHHHHCCCCEEEEECHHHHHCCCCH
SFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
QTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVA
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
KELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVT
HHCCCEEEEEECCCHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
SNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCEEEECCCCEEHH
QMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: tartrate [Periplasm]; succinate [Cytoplasm] [C]

Specific reaction: tartrate [Periplasm] + succinate [Cytoplasm] = tartrate [Cytoplasm] + succinate [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA