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The map label for this gene is ygcA [C]

Identifier: 148268369

GI number: 148268369

Start: 2082567

End: 2083928

Strand: Reverse

Name: ygcA [C]

Synonym: SaurJH9_1951

Alternate gene names: 148268369

Gene position: 2083928-2082567 (Counterclockwise)

Preceding gene: 148268370

Following gene: 148268368

Centisome position: 71.69

GC content: 32.97

Gene sequence:

>1362_bases
TTGCAAGCAATAGCTAAAAATGACATAAAAACGGGAACAGTTGTTGATTTAACGCATGAAGGCCATGGTGTTGTAAAAAT
AGATCGCTTTCCTATTTTCATACCACAAGCTTTAATTAATGAACAAATTGAATATAAAATTATCAAAGTAAAAAAGAACT
TTGCGATAGGTAAGTTGCTTAATATAAATACGAGAAGTGAGAATCGTGTTGCACCGCCATGTATATATTATGAACGTTGT
GGTGGGTGCCAACTTCAACACTTATCATACGAAGCACAACTTGAAATGAAAAAGGAACAAGTGATTAATTTGTTTCAGCG
AAAAGCGCATTTTGATAATTCTAAGATTAACGATACAGTTGGCATGACAGATCCTTGGAGATATCGAAACAAGTCCCAGA
TTCCAGTTGGTAAGAATGAACAGAATGAAGTTATTATGGGCTTTTATCGTCAAAGAAGCCATGACATTATTGACATGGAA
AGTTGTTTAATACAAGATTCACAACATCAAGAAGTGATGAATGAAGTTAAATCTATTTTAAAAGATTTAAATGTAAGTAT
TTATCAAGAACAATTGAAAAAAGGTTTAATGAGACATTTGGTTGTAAGAACAGGATATCATACAGACGAAATGATGATTA
TTTTTGTAACTAATGGTAAAAAGTGGCCACAAAAAAATGCTGTTGTTGAGAAGATATTAGATGCATTTCCTAATGTGACA
AGCATTAAACAAAACATTAATGATAGCCACTCTAATGTTATTATGGGACGTCAATCTATAACGCTATATGGTAAAGATAC
AATTATTGATCAATTAACAGATAGTACATTTAAAATAAGTGATCAGTCATTCTACCAAATTAATTCTGAACAAACAGAGA
AATTATATAATAAAGCAATTGAGTATGCGCAATTGACAGGTAATGAAGTTGTATTAGATACCTATTGTGGTATTGGAACA
ATAGGGCTATATATGGCACCACATGCAAAACATGTATACGGTGTTGAAGTAGTACCTTCTTCAATTGAAGACGCACAACA
AAATGCGACTATAAACCAATGCAATAATACAACTTTTGTCTGTGGGAAAGCTGAAGAAGTTATTTTACAATGGAAAGCAC
AAGGGATTAAACCAGATGTTGTAATGGTTGATCCGCCAAGAAAGGGCTGTGACGAAACGTTTATTCAGACTTTGCTTACA
TTAGAACCTAAGCGTATTGTCTATATTTCATGTAATCCCGCAACACAGCAACGTGATGCATTATTATTAGCTGAAAAATA
TCAACTTGAAGAGGTAACACCGGTAGATATGTTTCCACAAACAACACATGTTGAGACAGTGGCATTATTCAATTTGAAAT
AG

Upstream 100 bases:

>100_bases
ACAATTTAATCGAAGAATAAACAGAAATAGTGAAATATATAATGGCAGGTTAGGAAGCGCATAATTTTGTTCCTAACCTG
TTCATTTTGGAGGTAAAATT

Downstream 100 bases:

>100_bases
CGCACATGATTTGAGATAAAATTTCGCCTTAATAAGTGAAGAAAGAAGTCGTATATTAAAATTTTATTACAGCCAATTTA
CTTTCTTGATATGAACTTTT

Product: RNA methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 453; Mature: 453

Protein sequence:

>453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

Sequences:

>Translated_453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
>Mature_453_residues
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLLNINTRSENRVAPPCIYYERC
GGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTVGMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDME
SCLIQDSQHQEVMNEVKSILKDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAIEYAQLTGNEVVLDTYCGIGT
IGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFVCGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLT
LEPKRIVYISCNPATQQRDALLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK

Specific function: Could Be A 23s rRNA (Uracil-5-)-Methyltransferase. [C]

COG id: COG2265

COG function: function code J; SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RNA M5U methyltransferase family

Homologues:

Organism=Homo sapiens, GI34222389, Length=350, Percent_Identity=28, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI51173878, Length=350, Percent_Identity=28, Blast_Score=130, Evalue=4e-30,
Organism=Homo sapiens, GI269784678, Length=353, Percent_Identity=27.1954674220963, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI269784680, Length=353, Percent_Identity=27.1954674220963, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI269784676, Length=353, Percent_Identity=27.1954674220963, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI20149688, Length=353, Percent_Identity=27.1954674220963, Blast_Score=118, Evalue=1e-26,
Organism=Escherichia coli, GI1789148, Length=449, Percent_Identity=31.4031180400891, Blast_Score=189, Evalue=2e-49,
Organism=Escherichia coli, GI1787083, Length=380, Percent_Identity=25, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1790403, Length=211, Percent_Identity=27.4881516587678, Blast_Score=77, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71997438, Length=161, Percent_Identity=30.4347826086957, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322909, Length=449, Percent_Identity=23.3853006681514, Blast_Score=86, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24666579, Length=415, Percent_Identity=29.1566265060241, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1713_STAAN (Q7A4Q9)

Other databases:

- EMBL:   BA000018
- PIR:   H89977
- RefSeq:   NP_375004.1
- ProteinModelPortal:   Q7A4Q9
- SMR:   Q7A4Q9
- STRING:   Q7A4Q9
- EnsemblBacteria:   EBSTAT00000000757
- GeneID:   1124597
- GenomeReviews:   BA000018_GR
- KEGG:   sau:SA1713
- eggNOG:   COG2265
- GeneTree:   EBGT00050000024368
- HOGENOM:   HBG690163
- OMA:   RKGCDEA
- ProtClustDB:   CLSK885636
- BioCyc:   SAUR158879:SA1713-MONOMER
- InterPro:   IPR016027
- InterPro:   IPR001566
- InterPro:   IPR010280
- TIGRFAMs:   TIGR00479

Pfam domain/function: PF05958 tRNA_U5-meth_tr; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 51723; Mature: 51723

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS01230 TRMA_1; PS01231 TRMA_2

Important sites: ACT_SITE 411-411 BINDING 286-286 BINDING 315-315 BINDING 336-336 BINDING 384-384

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCEECCHHHHCCCCEEEEEEEECCCCEEEEE
NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
EECCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHH
KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHH
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
HHHHHCCCCCCEEEEECCEEEEEECHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHH
EYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFV
HHHHCCCCEEEEEECCCCCHHHHEECCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCEEE
CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
ECCHHHHHEEHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCE
LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
EEEEHHHCCCCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure
MQAIAKNDIKTGTVVDLTHEGHGVVKIDRFPIFIPQALINEQIEYKIIKVKKNFAIGKLL
CCCCCCCCCCCCCEEEEEECCCCEEEECCCCEECCHHHHCCCCEEEEEEEECCCCEEEEE
NINTRSENRVAPPCIYYERCGGCQLQHLSYEAQLEMKKEQVINLFQRKAHFDNSKINDTV
EECCCCCCCCCCCEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
GMTDPWRYRNKSQIPVGKNEQNEVIMGFYRQRSHDIIDMESCLIQDSQHQEVMNEVKSIL
CCCCCCCCCCCCCCCCCCCCCCCEEEEEHHHCCCCEECHHHHHHCCCHHHHHHHHHHHHH
KDLNVSIYQEQLKKGLMRHLVVRTGYHTDEMMIIFVTNGKKWPQKNAVVEKILDAFPNVT
HHCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCHH
SIKQNINDSHSNVIMGRQSITLYGKDTIIDQLTDSTFKISDQSFYQINSEQTEKLYNKAI
HHHHHCCCCCCEEEEECCEEEEEECHHHHHHHCCCEEEECCCCEEEECCHHHHHHHHHHH
EYAQLTGNEVVLDTYCGIGTIGLYMAPHAKHVYGVEVVPSSIEDAQQNATINQCNNTTFV
HHHHCCCCEEEEEECCCCCHHHHEECCCCCEEEEEEECCCCHHHHHHCCCCCCCCCCEEE
CGKAEEVILQWKAQGIKPDVVMVDPPRKGCDETFIQTLLTLEPKRIVYISCNPATQQRDA
ECCHHHHHEEHHCCCCCCCEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCE
LLLAEKYQLEEVTPVDMFPQTTHVETVALFNLK
EEEEHHHCCCCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11418146