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The map label for this gene is obgE

Identifier: 148268124

GI number: 148268124

Start: 1803193

End: 1804485

Strand: Reverse

Name: obgE

Synonym: SaurJH9_1701

Alternate gene names: 148268124

Gene position: 1804485-1803193 (Counterclockwise)

Preceding gene: 148268125

Following gene: 148268123

Centisome position: 62.08

GC content: 36.5

Gene sequence:

>1293_bases
ATGTTTGTCGATCAAGTCAAAATATCTCTTAAAGCCGGTGATGGTGGTAATGGTATTACCGCATATAGAAGAGAAAAATA
TGTACCATTTGGTGGACCAGCTGGCGGTGACGGTGGTAAAGGTGCTTCAGTCGTATTTGAAGTGGATGAAGGTTTAAGAA
CGTTATTAGATTTTAGATATCAACGTCATTTTAAAGCAAGCAAAGGTGAAAATGGCCAAAGTAGTAATATGCATGGTAAA
AATGCGGAAGATTTAGTATTAAAAGTTCCACCTGGTACAATTATTAAAAATGTTGAAACAGACGAAGTGTTAGCAGATCT
TGTTGAAGATGGTCAAAGAGCTGTAGTAGCGAAGGGCGGTCGAGGTGGCCGAGGTAATTCACGTTTTGCAACACCTAGAA
ACCCTGCACCTGACTTCAGTGAAAAAGGTGAACCAGGTGAGGAATTAGATGTATCTTTAGAATTGAAATTATTAGCTGAT
GTAGGATTAGTAGGTTTCCCTAGTGTGGGTAAATCGACTTTATTATCTATCGTTTCAAAAGCTAAGCCTAAAATTGGGGC
ATATCATTTTACAACGATTAAACCAAATCTAGGTGTTGTTTCAACGCCTGATCAACGTAGTTTTGTTATGGCAGATTTAC
CAGGTTTAATTGAAGGTGCATCTGATGGCGTTGGATTAGGACATCAATTTTTAAGACATGTAGAGAGAACAAAAGTTATT
GTTCACATGATTGATATGAGCGGTTCTGAAGGTAGAGAACCTATTGAAGATTATAAAGTCATTAATCAAGAATTAGCTGC
GTACGAGCAACGTTTAGAAGATAGACCTCAAATCGTAGTAGCTAACAAGATGGATTTACCTGAATCACAAGATAATTTAA
ACTTGTTTAAAGAAGAAATTGGCGAAGATGTGCCAGTTATTCCAGTTTCAACAATAACGCGTGATAATATTGATCAATTA
TTATATGCAATAGCAGATAAATTAGAAGAATATAAAGATGTTGACTTCACAGTTGAAGAAGAGGAGTCAGTTGGCATTAA
CCGAGTATTATATAAACATACACCGTCACAAGATAAATTTACAATTTCAAGAGATGATGATGGTGCTTATGTGGTAAGTG
GTAATGCTATTGAAAGAATGTTTAAAATGACTGACTTTAACAGTGATCCAGCAGTACGTCGATTTGCTCGTCAAATGCGT
TCGATGGGTATTGATGATGCACTTAGAGAACGTGGTTGTAAAAATGGTGATATCGTTAGAATTCTTGGCGGAGAATTTGA
ATTCGTTGAATAG

Upstream 100 bases:

>100_bases
CAACTGCATAAGAGCCCCTAATTATTTACAATATATAAGGGGCTCTAATATGCTATAATTATTGGGAAAATGAAAATTAT
ATGTAAAAGAGGTGAGATAT

Downstream 100 bases:

>100_bases
GAGCGTAACATGATGGACAATAAAGATTATAAAAAGTTTTATTTAATTAGAGAAGATGTCTTGCCTGAATCCGTGGTTAA
AACATTGAAGATTAAAGATG

Product: GTPase ObgE

Products: NA

Alternate protein names: GTP-binding protein obg

Number of amino acids: Translated: 430; Mature: 430

Protein sequence:

>430_residues
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGK
NAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQL
LYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMR
SMGIDDALRERGCKNGDIVRILGGEFEFVE

Sequences:

>Translated_430_residues
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGK
NAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQL
LYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMR
SMGIDDALRERGCKNGDIVRILGGEFEFVE
>Mature_430_residues
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRYQRHFKASKGENGQSSNMHGK
NAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGGRGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLAD
VGLVGFPSVGKSTLLSIVSKAKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEIGEDVPVIPVSTITRDNIDQL
LYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKFTISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMR
SMGIDDALRERGCKNGDIVRILGGEFEFVE

Specific function: An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in t

COG id: COG0536

COG function: function code R; Predicted GTPase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain

Homologues:

Organism=Homo sapiens, GI24308117, Length=337, Percent_Identity=39.1691394658754, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI111955139, Length=354, Percent_Identity=33.6158192090396, Blast_Score=183, Evalue=2e-46,
Organism=Homo sapiens, GI111955063, Length=246, Percent_Identity=34.1463414634146, Blast_Score=136, Evalue=4e-32,
Organism=Homo sapiens, GI4758796, Length=118, Percent_Identity=38.135593220339, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI58761500, Length=135, Percent_Identity=31.1111111111111, Blast_Score=72, Evalue=9e-13,
Organism=Homo sapiens, GI4557537, Length=92, Percent_Identity=40.2173913043478, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1789574, Length=326, Percent_Identity=44.478527607362, Blast_Score=261, Evalue=7e-71,
Organism=Escherichia coli, GI1787454, Length=131, Percent_Identity=38.1679389312977, Blast_Score=81, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17508313, Length=324, Percent_Identity=37.3456790123457, Blast_Score=165, Evalue=4e-41,
Organism=Caenorhabditis elegans, GI17552324, Length=313, Percent_Identity=30.3514376996805, Blast_Score=142, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17555344, Length=153, Percent_Identity=32.6797385620915, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509631, Length=139, Percent_Identity=32.3741007194245, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71981008, Length=118, Percent_Identity=38.135593220339, Blast_Score=72, Evalue=4e-13,
Organism=Saccharomyces cerevisiae, GI6321962, Length=193, Percent_Identity=36.2694300518135, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6319281, Length=126, Percent_Identity=34.9206349206349, Blast_Score=70, Evalue=5e-13,
Organism=Drosophila melanogaster, GI20129375, Length=333, Percent_Identity=40.2402402402402, Blast_Score=200, Evalue=1e-51,
Organism=Drosophila melanogaster, GI24585318, Length=368, Percent_Identity=32.6086956521739, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24640873, Length=142, Percent_Identity=33.0985915492958, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640877, Length=142, Percent_Identity=33.0985915492958, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24640875, Length=142, Percent_Identity=33.0985915492958, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI17981711, Length=153, Percent_Identity=33.9869281045752, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI21356473, Length=163, Percent_Identity=34.3558282208589, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): OBG_STAA1 (A7X361)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442221.1
- ProteinModelPortal:   A7X361
- SMR:   A7X361
- STRING:   A7X361
- EnsemblBacteria:   EBSTAT00000004210
- GeneID:   5559357
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1631
- eggNOG:   COG0536
- GeneTree:   EBGT00050000024452
- HOGENOM:   HBG716038
- OMA:   HFTTLVP
- ProtClustDB:   PRK12297
- BioCyc:   SAUR418127:SAHV_1631-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01454
- InterPro:   IPR014100
- InterPro:   IPR015349
- InterPro:   IPR006074
- InterPro:   IPR006073
- InterPro:   IPR006169
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:2.70.210.12
- PANTHER:   PTHR11702:SF3
- PIRSF:   PIRSF002401
- PRINTS:   PR00326
- TIGRFAMs:   TIGR02729
- TIGRFAMs:   TIGR03595
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF09269 DUF1967; PF01018 GTP1_OBG; PF01926 MMR_HSR1; SSF102741 GTP-bd_prot_GTP1/OBG_C; SSF82051 GTP1_OBG_sub

EC number: NA

Molecular weight: Translated: 47236; Mature: 47236

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS00905 GTP1_OBG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRY
CCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHH
QRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCHHCCCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
AKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
CCCCCCEEEEEEECCCCCEEECCCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHEEE
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHH
GEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCE
TISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVR
EEEECCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEE
ILGGEFEFVE
EECCCEEECC
>Mature Secondary Structure
MFVDQVKISLKAGDGGNGITAYRREKYVPFGGPAGGDGGKGASVVFEVDEGLRTLLDFRY
CCCCEEEEEEEECCCCCCCCHHHHCCCCCCCCCCCCCCCCCCEEEEECHHHHHHHHHHHH
QRHFKASKGENGQSSNMHGKNAEDLVLKVPPGTIIKNVETDEVLADLVEDGQRAVVAKGG
HHHHCCCCCCCCCCCCCCCCCCCCEEEECCCCHHCCCCCHHHHHHHHHHCCCEEEEEECC
RGGRGNSRFATPRNPAPDFSEKGEPGEELDVSLELKLLADVGLVGFPSVGKSTLLSIVSK
CCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCCCCCCCCCCHHHHHHHHHH
AKPKIGAYHFTTIKPNLGVVSTPDQRSFVMADLPGLIEGASDGVGLGHQFLRHVERTKVI
CCCCCCEEEEEEECCCCCEEECCCCCCEEEECCCHHHCCCCCCCCHHHHHHHHHHHHEEE
VHMIDMSGSEGREPIEDYKVINQELAAYEQRLEDRPQIVVANKMDLPESQDNLNLFKEEI
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHH
GEDVPVIPVSTITRDNIDQLLYAIADKLEEYKDVDFTVEEEESVGINRVLYKHTPSQDKF
CCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEECCCCCCCE
TISRDDDGAYVVSGNAIERMFKMTDFNSDPAVRRFARQMRSMGIDDALRERGCKNGDIVR
EEEECCCCCEEEECHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCHHHHHCCCCCCCEEE
ILGGEFEFVE
EECCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA