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The map label for this gene is aroE

Identifier: 148268079

GI number: 148268079

Start: 1753115

End: 1753921

Strand: Reverse

Name: aroE

Synonym: SaurJH9_1653

Alternate gene names: 148268079

Gene position: 1753921-1753115 (Counterclockwise)

Preceding gene: 148268080

Following gene: 148268078

Centisome position: 60.34

GC content: 31.35

Gene sequence:

>807_bases
ATGAAATTTGCAGTTATCGGAAATCCTATTTCACATTCCTTGTCGCCCGTTATGCATAGAGCAAATTTTAATTCTTTAGG
ATTAGATGATACTTATGAAGCTTTAAATATTCCAATTGAAGATTTTCATTTAATTAAAGAAATTATTTCGAAAAAAGAAT
TAGATGGCTTTAATATCACAATTCCTCATAAAGAACGTATCATACCGTATTTAGATTATGTTGATGAACAAGCGATTAAT
GCAGGTGCAGTTAACACTGTTTTGATAAAAGATGGCAAGTGGATAGGGTATAATACAGATGGTATTGGTTATGTTAAAGG
ATTGCACAGCGTTTATCCAGATTTAGAAAATGCATACATTTTAATTTTGGGCGCAGGTGGTGCAAGTAAAGGTATTGCTT
ATGAATTAGCAAAATTTGTAAAGCCCAAATTAACTGTTGCGAATAGAACGATGGCTCGTTTTGAATCTTGGAATTTAAAT
ATAAACCAAATTTCATTGGCAGATGCTGAAAAGTATTTAGCTGAATTCGATATCGTTATTAATACAACACCAGCGGGTAT
GGCTGGAAATAACGAAAGTATTATTAATTTAAAACATCTTTCTCCCAATACTTTAATGAGTGATATTGTTTATATACCGT
ATAAAACACCTATTTTAGAGGAAGCAGAGCGCAAGGGAAACCATATTTATAATGGCTTAGATATGTTTGTTTACCAAGGT
GCGGAAAGCTTTAAAATTTGGACTAATAAAGATGCTGATATTAATTCTATGAAAACAGCAGTTTTACAACAATTAAAAGG
AGAATAA

Upstream 100 bases:

>100_bases
GGCTTTATAACTATAGGACCAGGAGCTAAAGTAATCGTTCGTGTTCCTAAAAATGTTGATGTTGTATTAAGAAATTCTAT
TTTATAAGGTGATTTAAAAA

Downstream 100 bases:

>100_bases
CATATGCTTACTGGCAAACAAAAAAGATACTTAAGAAGTTTAGCACACAATATTGATCCGATTTTTCAAATTGGAAAAGG
CGGTATCAACGAAAATATGA

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDYVDEQAIN
AGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
AESFKIWTNKDADINSMKTAVLQQLKGE

Sequences:

>Translated_268_residues
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDYVDEQAIN
AGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
AESFKIWTNKDADINSMKTAVLQQLKGE
>Mature_268_residues
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNITIPHKERIIPYLDYVDEQAIN
AGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYILILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLN
INQISLADAEKYLAEFDIVINTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
AESFKIWTNKDADINSMKTAVLQQLKGE

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1787983, Length=279, Percent_Identity=31.8996415770609, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789675, Length=274, Percent_Identity=33.2116788321168, Blast_Score=135, Evalue=4e-33,
Organism=Saccharomyces cerevisiae, GI6320332, Length=280, Percent_Identity=28.2142857142857, Blast_Score=94, Evalue=3e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROE_STAA1 (A7X302)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442173.1
- ProteinModelPortal:   A7X302
- SMR:   A7X302
- STRING:   A7X302
- EnsemblBacteria:   EBSTAT00000003628
- GeneID:   5559981
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1583
- eggNOG:   COG0169
- GeneTree:   EBGT00050000025479
- HOGENOM:   HBG553408
- OMA:   TLFMKKG
- ProtClustDB:   CLSK885454
- BioCyc:   SAUR418127:SAHV_1583-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00222
- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR00507

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N

EC number: =1.1.1.25

Molecular weight: Translated: 29866; Mature: 29866

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: NA

Important sites: ACT_SITE 64-64

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNIT
CEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
IPHKERIIPYLDYVDEQAINAGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYI
ECCHHCCCHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCEE
LILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLNINQISLADAEKYLAEFDIVI
EEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHEEEEEE
NTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
ECCCCCCCCCCCCEEEEECCCCCHHHHCEEEECCCCCHHHHHHHCCCEECCCCEEEEECC
AESFKIWTNKDADINSMKTAVLQQLKGE
CCCEEEEECCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFAVIGNPISHSLSPVMHRANFNSLGLDDTYEALNIPIEDFHLIKEIISKKELDGFNIT
CEEEEECCCHHHHHHHHHHHCCCCCCCCCCCHHHHCCCHHHHHHHHHHHHHHCCCCCEEE
IPHKERIIPYLDYVDEQAINAGAVNTVLIKDGKWIGYNTDGIGYVKGLHSVYPDLENAYI
ECCHHCCCHHHHHHHHHHCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHCCCCCCCEE
LILGAGGASKGIAYELAKFVKPKLTVANRTMARFESWNLNINQISLADAEKYLAEFDIVI
EEEECCCCCCCHHHHHHHHCCCCEEEHHHHHHHHHHCCCCEEEEEHHHHHHHHHEEEEEE
NTTPAGMAGNNESIINLKHLSPNTLMSDIVYIPYKTPILEEAERKGNHIYNGLDMFVYQG
ECCCCCCCCCCCCEEEEECCCCCHHHHCEEEECCCCCHHHHHHHCCCEECCCCEEEEECC
AESFKIWTNKDADINSMKTAVLQQLKGE
CCCEEEEECCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA