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The map label for this gene is hrcA

Identifier: 148268066

GI number: 148268066

Start: 1740853

End: 1741830

Strand: Reverse

Name: hrcA

Synonym: SaurJH9_1640

Alternate gene names: 148268066

Gene position: 1741830-1740853 (Counterclockwise)

Preceding gene: 148268067

Following gene: 148268065

Centisome position: 59.92

GC content: 28.43

Gene sequence:

>978_bases
ATGATTACAGATAGGCAATTGAGTATATTAAACGCAATTGTTGAGGATTATGTTGATTTTGGACAACCCGTTGGTTCTAA
AACACTAATTGAGCGACATAACTTGAATGTTAGTCCTGCTACAATTAGAAATGAGATGAAACAGCTTGAAGATTTAAACT
ATATCGAAAAGACACATAGTTCTTCAGGGCGTTCGCCATCACAATTAGGTTTTAGGTATTATGTCAATCGTTTACTTGAA
CAAACATCTCATCAAAAAACAAATAAATTAAGACGATTAAATCAATTGTTAGTTGAGAATCAATATGATGTATCATCAGC
ATTGACATATTTTGCAGATGAATTATCAAATATATCTCAATATACAACTTTAGTTGTTCATCCTAATCATAAACAAGATA
TTATCAATAATGTACATTTGATTCGTGCTAATCCTAATTTAGTTATAATGGTTATCGTATTTTCATCAGGTCATGTTGAG
CATGTACATCTTGCTTCAGACATACCGTTTAGTAATGATAAACTAAATACAATATCAAATTTTGTTACTAACAAACTAAC
TGAGTTTAATCAGAATTTACAAGATGATATTGTCTCTTTTGTTCAATCAGAGCAGGAAGAAATATTTATCAATAAATTGA
TAAATACGATGAATAATCATATTTCTAATCAAAGTAATAGCATTTATATGGGTGGAAAGGTTAAACTTATTGATGCATTG
AATGAAAGTAATGTATCTTCAATTCAGCCCATTCTACAATATATAGAATCAAATAGAATTGCAGAATTATTACAAGATAT
ATCTTCACCAAATATTAATGTAAAAATTGGTAATGAAATTGATGACAGCTTAAGTGATATTTCAATTGTAACAAGTCAAT
ATCATTTTGATGAAACGTTAAAAGGTCAAATCGCTGTGATTGGACCTACAGCTATGCATTATCAAAATGTCATTCAATTA
TTAAATAGAATTTGGTAA

Upstream 100 bases:

>100_bases
AAAAAATTGAAATTTCGAGTCTTTAACATTGACTTACTTTGACCAATTTGATAAATTATAATTAGCACTTGAGATAAGTG
AGTGCTAATGAGGTGAAAAC

Downstream 100 bases:

>100_bases
TGATGGATTAGAAAGTATTGGAGGACAGAAAATGACAAATAAAGACGAATCAGTTGAAAAAAACACTGAATCAACAGTTG
AAGAAACAAACATCAAACAA

Product: heat-inducible transcription repressor HrcA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLE
QTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
HVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDAL
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQL
LNRIW

Sequences:

>Translated_325_residues
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLE
QTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
HVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDAL
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQL
LNRIW
>Mature_325_residues
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLE
QTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVE
HVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDAL
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQL
LNRIW

Specific function: Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons

COG id: COG1420

COG function: function code K; Transcriptional regulator of heat shock gene

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hrcA family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HRCA_STAA1 (A7X2Y4)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001442159.1
- ProteinModelPortal:   A7X2Y4
- SMR:   A7X2Y4
- STRING:   A7X2Y4
- EnsemblBacteria:   EBSTAT00000003977
- GeneID:   5559127
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_1569
- eggNOG:   COG1420
- GeneTree:   EBGT00050000024734
- HOGENOM:   HBG729878
- OMA:   LEQPHTS
- ProtClustDB:   CLSK885445
- BioCyc:   SAUR418127:SAHV_1569-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00081
- InterPro:   IPR002571
- InterPro:   IPR021153
- InterPro:   IPR011991
- Gene3D:   G3DSA:1.10.10.10
- PIRSF:   PIRSF005485
- TIGRFAMs:   TIGR00331

Pfam domain/function: PF01628 HrcA

EC number: NA

Molecular weight: Translated: 36989; Mature: 36989

Theoretical pI: Translated: 5.71; Mature: 5.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHH
YTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISN
HEEEEECCCCHHHHHCCEEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHH
FVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECC
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETL
CCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHC
KGQIAVIGPTAMHYQNVIQLLNRIW
CCCEEEECCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHS
CCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHCC
SSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCHHH
YTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISN
HEEEEECCCCHHHHHCCEEEEEECCCEEEEEEEECCCCEEEEEECCCCCCCCCHHHHHHH
FVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDAL
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEEEECC
NESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETL
CCCCHHHHHHHHHHHHCHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHCCHHC
KGQIAVIGPTAMHYQNVIQLLNRIW
CCCEEEECCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA