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The map label for this gene is yaeL [C]

Identifier: 148267752

GI number: 148267752

Start: 1375185

End: 1376471

Strand: Direct

Name: yaeL [C]

Synonym: SaurJH9_1322

Alternate gene names: 148267752

Gene position: 1375185-1376471 (Clockwise)

Preceding gene: 148267751

Following gene: 148267753

Centisome position: 47.31

GC content: 33.26

Gene sequence:

>1287_bases
GTGAGCTATTTAGTTACAATAATTGCATTTATTATTGTTTTTGGTGTACTAGTAACTGTTCATGAATATGGACATATGTT
TTTTGCGAAAAGAGCAGGCATTATGTGTCCAGAATTTGCGATCGGTATGGGGCCAAAAATTTTTAGTTTTAGAAAAAATG
AAACACTTTACACTATTAGGTTATTGCCTGTTGGTGGATATGTTCGTATGGCAGGAGATGGCTTAGAAGAGCCACCAGTC
GAGCCCGGTATGAACGTTAAAATTAAACTGAATGAAGAAAATGAAATAACACATATCATATTAGATGATCATCATAAGTT
TCAACAAATTGAAGCGATCGAAGTTAAAAAATGTGATTTTAAGGATGACTTATTCATAGAAGGTATCACTGCTTATGATA
ATGAAAGACATCATTTTAAAATTGCTAGAAAGTCTTTCTTTGTTGAAAATGGTAGCTTAGTTCAAATTGCTCCGAGAGAC
AGACAATTTGCACATAAAAAGCCATGGCCGAAATTTTTAACATTATTTGCGGGACCGTTATTTAACTTTATATTAGCTTT
AGTCCTATTTATTGGTCTTGCATATTATCAAGGTACACCTACGTCTACTGTAGAACAAGTCGCAGATAAGTATCCAGCTC
AACAAGCAGGATTACAAAAAGGTGATAAAATTGTTCAAATTGGCAAATATAAAATATCTGAATTTGATGATGTTGATAAG
GCGTTAGATAAAGTTAAAGATAATAAGACGACTGTTAAATTTGAACGTGATGGTAAAACGAAGTCAGTTGAATTAACACC
TAAAAAGACTGAAAGAAAACTGACTAAAGTAAGTTCAGAGACGAAGTATGTTCTCGGATTCCAACCAGCGAGTGAACATA
CACTTTTCAAACCAATTGTATATGGATTTGAAAGCTTTTTGAAAGGTAGTACACTAATTTTTACAGCTGTAGTCGGTATG
TTGGCTAGTATATTTACGGGCGGATTCTCATTTGATATGTTAAATGGTCCGGTTGGTATTTATCATAACGTCGACTCAGT
TGTTAAAGCGGGTATCATTAGCTTAATTGGTTACACTGCGTTATTAAGTGTAAACTTAGGTATTATGAATTTAATTCCTA
TTCCTGCACTAGACGGTGGTCGTATTTTATTTGTTATATATGAAGCGATTTTCAGAAAACCAGTTAATAAAAAAGCGGAA
ACAACGATTATTGCTATTGGTGCCATTTTCATGGTCGTTATTATGATATTAGTAACGTGGAATGATATTCGACGATATTT
CTTATAA

Upstream 100 bases:

>100_bases
ATTTTGTGATTTGTCAGTATCATATTATAATGACTTATGTTACGTATACAGCAATCAATTTTAAAATAAAAGAAATTTAT
AAACAATCGAGGTGTAGCGA

Downstream 100 bases:

>100_bases
TTTAGGAGGATAAATAATTATGAAGCAATCCAAAGTTTTTATACCAACGATGCGTGATGTGCCATCAGAAGCAGAAGCAC
AAAGTCATCGTTTATTATTG

Product: membrane-associated zinc metalloprotease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 428; Mature: 427

Protein sequence:

>428_residues
MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPV
EPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRD
RQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
ALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTKVSSETKYVLGFQPASEHTLFKPIVYGFESFLKGSTLIFTAVVGM
LASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAE
TTIIAIGAIFMVVIMILVTWNDIRRYFL

Sequences:

>Translated_428_residues
MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPV
EPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRD
RQFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
ALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTKVSSETKYVLGFQPASEHTLFKPIVYGFESFLKGSTLIFTAVVGM
LASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAE
TTIIAIGAIFMVVIMILVTWNDIRRYFL
>Mature_427_residues
SYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIRLLPVGGYVRMAGDGLEEPPVE
PGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDFKDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDR
QFAHKKPWPKFLTLFAGPLFNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDKA
LDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTKVSSETKYVLGFQPASEHTLFKPIVYGFESFLKGSTLIFTAVVGML
ASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTALLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAET
TIIAIGAIFMVVIMILVTWNDIRRYFL

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain

Homologues:

Organism=Escherichia coli, GI1786373, Length=234, Percent_Identity=28.6324786324786, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): Y1105_STAAN (P63333)

Other databases:

- EMBL:   BA000018
- PIR:   A89900
- RefSeq:   NP_374378.1
- ProteinModelPortal:   P63333
- SMR:   P63333
- STRING:   P63333
- EnsemblBacteria:   EBSTAT00000000365
- GeneID:   1123936
- GenomeReviews:   BA000018_GR
- KEGG:   sau:SA1105
- eggNOG:   COG0750
- GeneTree:   EBGT00050000025031
- HOGENOM:   HBG664087
- OMA:   HGTEFVV
- ProtClustDB:   CLSK2460859
- BioCyc:   SAUR158879:SA1105-MONOMER
- GO:   GO:0006508
- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915
- SMART:   SM00228
- TIGRFAMs:   TIGR00054

Pfam domain/function: PF02163 Peptidase_M50; SSF50156 PDZ

EC number: NA

Molecular weight: Translated: 48117; Mature: 47986

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: PS50106 PDZ; PS00142 ZINC_PROTEASE

Important sites: ACT_SITE 22-22

Signals:

None

Transmembrane regions:

HASH(0xe027ff8)-; HASH(0xe75cbd8)-; HASH(0xc9d49f0)-; HASH(0xebad08c)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHEEEECCCEEEEEE
LLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDF
EEECCCEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHEEEEECCCC
KDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPL
CCCEEEEEEECCCCCCHHEEEEHHHEEEECCCEEEECCCCCHHCCCCCCHHHHHHHHHHH
FNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCCEEEECCEECCCHHHHHH
ALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTKVSSETKYVLGFQPASEHTLFKPIV
HHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
YGFESFLKGSTLIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTA
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHH
LLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTW
HHHHCCCHHEEECCCCCCCCEEHHHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHHHHHH
NDIRRYFL
HHHHHHCH
>Mature Secondary Structure 
SYLVTIIAFIIVFGVLVTVHEYGHMFFAKRAGIMCPEFAIGMGPKIFSFRKNETLYTIR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHEEEECCCEEEEEE
LLPVGGYVRMAGDGLEEPPVEPGMNVKIKLNEENEITHIILDDHHKFQQIEAIEVKKCDF
EEECCCEEEECCCCCCCCCCCCCCEEEEEECCCCCEEEEEECCCCHHHHHHEEEEECCCC
KDDLFIEGITAYDNERHHFKIARKSFFVENGSLVQIAPRDRQFAHKKPWPKFLTLFAGPL
CCCEEEEEEECCCCCCHHEEEEHHHEEEECCCEEEECCCCCHHCCCCCCHHHHHHHHHHH
FNFILALVLFIGLAYYQGTPTSTVEQVADKYPAQQAGLQKGDKIVQIGKYKISEFDDVDK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCHHHHCCCCCCCEEEECCEECCCHHHHHH
ALDKVKDNKTTVKFERDGKTKSVELTPKKTERKLTKVSSETKYVLGFQPASEHTLFKPIV
HHHHHCCCCEEEEEECCCCCEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHH
YGFESFLKGSTLIFTAVVGMLASIFTGGFSFDMLNGPVGIYHNVDSVVKAGIISLIGYTA
HHHHHHHCCCHHHHHHHHHHHHHHHCCCCEEEECCCCEEEEECHHHHHHHHHHHHHHHHH
LLSVNLGIMNLIPIPALDGGRILFVIYEAIFRKPVNKKAETTIIAIGAIFMVVIMILVTW
HHHHCCCHHEEECCCCCCCCEEHHHHHHHHHCCCCCCCHHHHEEHHHHHHHHHHHHHHHH
NDIRRYFL
HHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11418146