Definition Staphylococcus aureus subsp. aureus JH9, complete genome.
Accession NC_009487
Length 2,906,700

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The map label for this gene is ftsY [H]

Identifier: 148267726

GI number: 148267726

Start: 1345289

End: 1346539

Strand: Direct

Name: ftsY [H]

Synonym: SaurJH9_1294

Alternate gene names: 148267726

Gene position: 1345289-1346539 (Clockwise)

Preceding gene: 148267725

Following gene: 148267727

Centisome position: 46.28

GC content: 34.77

Gene sequence:

>1251_bases
ATGAGCTTTTTTAAACGCTTAAAAGATAAGTTTGCAACAAATAAAGAAAATGAAGAAGTTAAATCCTTAAGAGAAGAACA
AGGTCAAGACAAATTAGAAGATACACATTCTGAAGGTTCAACGCAGGACGTAAATGATTTAGCAGAAAATGCTGAAGTGA
AAAAGAAGCCACGCAAGTTGAGTGAAGCGGATTTTGATGACGATGGCTTAATATCAATTGAAGATTTTGAAGAAATTGAA
GCTCAAAAAATGGGTGCTAAATTTAAAGCAGGACTCGAAAAATCTCGTCAAAATTTCCAAGAACAATTAAATAATTTGAT
AGCGAGATATCGTAAAGTAGATGAAGACTTTTTTGAAGCTTTAGAAGAAATGTTAATCACTGCAGACGTCGGTTTTAATA
CAGTGATGACGTTAACTGAAGAATTACGTATGGAAGCACAACGACGTAATATTCAAGATACTGAAGATTTGCGTGAAGTC
ATTGTTGAAAAAATCGTAGAGATTTACCATCAAGAAGATGATAATTCAGAAGCTATGAACATAGAAGATGGTCGTTTAAA
TGTCATTTTAATGGTCGGTGTGAATGGTGTTGGTAAAACAACAACAATTGGAAAATTAGCTTACCGATATAAAATGGAAG
GTAAAAAAGTAATGTTAGCTGCGGGCGATACTTTTAGAGCGGGTGCTATTGATCAATTGAAAGTTTGGGGCGAACGTGTT
GGTGTAGATGTAATTAGCCAAAGTGAAGGTTCTGATCCAGCTGCTGTTATGTATGATGCGATTAATGCCGCTAAAAACAA
AGGTGTTGATATTTTAATCTGTGATACCGCTGGACGTTTACAAAATAAAACAAATCTAATGCAAGAATTAGAAAAAGTTA
AGCGTGTAATTAATCGAGCAGTGCCAGATGCGCCTCATGAAGCATTACTATGTTTAGATGCTACAACTGGTCAGAATGCG
TTGTCACAAGCTAGAAACTTTAAAGAAGTAACAAATGTTACAGGTATTGTATTAACGAAATTAGATGGTACAGCCAAAGG
TGGTATCGTATTAGCCATTCGTAATGAATTGCACATTCCAGTTAAATATGTAGGTTTAGGTGAGCAATTAGATGACTTAC
AACCATTTAACCCTGAAAGTTATGTCTACGGCTTATTCGCTGATATGATTGAACAAAATGACGAAATAACAACAGTTGAA
AATGATCAAATTGTAACAGAAGAAAAGGACGATAATCATGGGGCAAAATGA

Upstream 100 bases:

>100_bases
CAGATAGGTTATACGGTGTAACAATGCAAGAATCAGGTGTTACTAAACTTGTGAGTGTGAATTTAAATACAATAGATGAT
GTGTTGAAGGAGGAGCAATA

Downstream 100 bases:

>100_bases
TTTAGTTAAAACGTTACGAATGAATTATTTGTTTGATTTTTATCAATCCTTATTGACGAATAAACAACGTAATTATTTGG
AATTATTTTATCTCGAAGAT

Product: signal recognition particle-docking protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 416; Mature: 415

Protein sequence:

>416_residues
MSFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIE
AQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREV
IVEKIVEIYHQEDDNSEAMNIEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERV
GVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNA
LSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNDEITTVE
NDQIVTEEKDDNHGAK

Sequences:

>Translated_416_residues
MSFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIE
AQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREV
IVEKIVEIYHQEDDNSEAMNIEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERV
GVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNA
LSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNDEITTVE
NDQIVTEEKDDNHGAK
>Mature_415_residues
SFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKLSEADFDDDGLISIEDFEEIEA
QKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEALEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVI
VEKIVEIYHQEDDNSEAMNIEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERVG
VDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRAVPDAPHEALLCLDATTGQNAL
SQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIPVKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNDEITTVEN
DQIVTEEKDDNHGAK

Specific function: Required for normal cell growth and morphogenesis; translocation of at least 1 protein is impaired in its absence [H]

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=296, Percent_Identity=31.0810810810811, Blast_Score=149, Evalue=6e-36,
Organism=Homo sapiens, GI226371618, Length=281, Percent_Identity=31.3167259786477, Blast_Score=145, Evalue=7e-35,
Organism=Homo sapiens, GI23308697, Length=319, Percent_Identity=28.2131661442006, Blast_Score=108, Evalue=7e-24,
Organism=Homo sapiens, GI295424842, Length=319, Percent_Identity=28.2131661442006, Blast_Score=108, Evalue=8e-24,
Organism=Homo sapiens, GI89061728, Length=168, Percent_Identity=29.1666666666667, Blast_Score=89, Evalue=8e-18,
Organism=Escherichia coli, GI1789874, Length=302, Percent_Identity=49.6688741721854, Blast_Score=293, Evalue=2e-80,
Organism=Escherichia coli, GI1788963, Length=298, Percent_Identity=32.5503355704698, Blast_Score=158, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=291, Percent_Identity=30.5841924398625, Blast_Score=144, Evalue=9e-35,
Organism=Caenorhabditis elegans, GI193206261, Length=222, Percent_Identity=34.2342342342342, Blast_Score=108, Evalue=4e-24,
Organism=Saccharomyces cerevisiae, GI6325345, Length=266, Percent_Identity=33.8345864661654, Blast_Score=157, Evalue=4e-39,
Organism=Saccharomyces cerevisiae, GI6320498, Length=313, Percent_Identity=26.8370607028754, Blast_Score=90, Evalue=5e-19,
Organism=Drosophila melanogaster, GI17647949, Length=309, Percent_Identity=30.7443365695793, Blast_Score=145, Evalue=5e-35,
Organism=Drosophila melanogaster, GI24641198, Length=228, Percent_Identity=30.7017543859649, Blast_Score=99, Evalue=8e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 46644; Mature: 46513

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS00018 EF_HAND_1 ; PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKL
CCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHH
SEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEA
CCCCCCCCCEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
IEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERV
CCCCCEEEEEEEECCCCCCCHHHHHHHHHEEECCCEEEEEECCCCCCCCHHHHHHHHHHH
GVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRA
CCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
VPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIP
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCC
VKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNDEITTVENDQIVTEEKDDNHGAK
EEEECCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCCC
>Mature Secondary Structure 
SFFKRLKDKFATNKENEEVKSLREEQGQDKLEDTHSEGSTQDVNDLAENAEVKKKPRKL
CHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHCCCCCCCHHHHHHHCCHHHHHHHHH
SEADFDDDGLISIEDFEEIEAQKMGAKFKAGLEKSRQNFQEQLNNLIARYRKVDEDFFEA
CCCCCCCCCEEEHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHH
LEEMLITADVGFNTVMTLTEELRMEAQRRNIQDTEDLREVIVEKIVEIYHQEDDNSEAMN
HHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCEE
IEDGRLNVILMVGVNGVGKTTTIGKLAYRYKMEGKKVMLAAGDTFRAGAIDQLKVWGERV
CCCCCEEEEEEEECCCCCCCHHHHHHHHHEEECCCEEEEEECCCCCCCCHHHHHHHHHHH
GVDVISQSEGSDPAAVMYDAINAAKNKGVDILICDTAGRLQNKTNLMQELEKVKRVINRA
CCEEEECCCCCCCHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
VPDAPHEALLCLDATTGQNALSQARNFKEVTNVTGIVLTKLDGTAKGGIVLAIRNELHIP
CCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCEEEEEECCCCCC
VKYVGLGEQLDDLQPFNPESYVYGLFADMIEQNDEITTVENDQIVTEEKDDNHGAK
EEEECCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCEEEECCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584053; 9384377; 8654983 [H]