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The map label for this gene is typA [H]

Identifier: 148267602

GI number: 148267602

Start: 1210672

End: 1212519

Strand: Direct

Name: typA [H]

Synonym: SaurJH9_1169

Alternate gene names: 148267602

Gene position: 1210672-1212519 (Clockwise)

Preceding gene: 148267600

Following gene: 148267605

Centisome position: 41.65

GC content: 35.06

Gene sequence:

>1848_bases
ATGACTAATAAAAGAGAAGATGTCCGCAATATAGCAATTATTGCTCACGTTGACCATGGTAAAACAACTTTAGTAGATGA
GTTGTTAAAACAATCTGGTATATTCAGAGAAAATGAACATGTCGATGAACGTGCAATGGACTCTAACGATATCGAAAGAG
AGCGTGGAATTACGATTCTAGCCAAAAATACGGCTGTTGATTATAAAGGTACACGTATTAATATTTTGGATACACCAGGA
CATGCAGACTTTGGTGGAGAAGTAGAACGTATTATGAAAATGGTTGATGGGGTTGTCTTAGTAGTAGATGCGTATGAAGG
TACAATGCCTCAAACACGTTTTGTACTTAAAAAAGCGCTAGAACAAAACCTGAAACCTGTTGTTGTTGTTAATAAAATTG
ATAAACCATCAGCACGTCCAGAGGGTGTTGTAGATGAAGTTTTAGATTTATTTATTGAATTAGAAGCAAACGATGAACAA
TTAGAATTCCCTGTTGTTTATGCTTCAGCAGTAAATGGAACAGCTAGCTTAGATCCTGAAAAACAAGATGATAATTTACA
ATCATTATATGAAACAATTATTGATTATGTACCAGCTCCAATTGATAACAGTGATGAGCCATTACAATTCCAAGTAGCAT
TGTTGGACTACAATGATTATGTTGGACGTATTGGTATTGGTCGTGTATTCAGAGGTAAAATGCGTGTCGGAGATAATGTA
TCACTAATTAAATTAGACGGTACAGTGAAAAACTTCCGTGTAACTAAAATCTTTGGTTACTTTGGATTAAAACGTTTAGA
AATTGAAGAAGCACAAGCTGGAGATTTAATTGCTGTTTCAGGTATGGAAGACATTAATGTTGGTGAAACTGTAACACCAC
ATGACCATCAAGAAGCATTGCCAGTTCTACGTATTGATGAGCCTACTCTTGAAATGACATTTAAAGTTAACAATTCTCCA
TTTGCTGGCCGTGAAGGTGACTTTGTAACAGCACGTCAAATTCAAGAACGTTTAAATCAACAATTAGAAATAGATGTATC
TTTGAAAGTTTCTAACACAGATTCTCCAGATACATGGGTAGTTGCTGGTCGCGGTGAATTGCATTTATCAATCCTTATTG
AAAATATGCGTCGTGAAGGTTATGAATTACAAGTTTCAAAACCACAAGTAATTATTAAAGAAATAGATGGTGTAATGTGT
GAACCATTTGAACGTGTGCAATGTGAAGTGCCACAAGAAAATGCAGGTGCTGTTATTGAATCATTAGGTGCACGTAAAGG
TGAAATGGTTGATATGACTACAACTGATAATGGACTTACACGTTTAATCTTTAATGTACCGGCTCGTGGTATGATTGGTT
ATACGACTGAATTTATGTCAATGACAAGAGGTTACGGTATTATTAACCATACATTTGAAGAATTTAGACCACGTATTAAA
GCACAAATTGGCGGTCGTCGTAATGGTGCATTAATTTCAATGGATCAAGGTTCTGCAAGTACTTATGCCATTTTGGGACT
TGAAGATAGAGGTGTAAACTTCATGGAACCTGGTACTGAAGTTTATGAAGGTATGATTGTTGGTGAACATAATCGTGAAA
ATGATTTAACTGTTAACATCACTAAAACAAAACATCAAACTAACGTACGTTCTGCAACGAAAGACCAAACACAAACAATG
AATAGACCGCGTATTCTAACATTGGAAGAAGCGTTACAATTCATTAATGATGATGAACTTGTTGAGGTTACACCAGAAAG
TATACGTTTAAGAAAGAAAATTTTAAACAAAAATGTTCGTGAAAAAGAAGCAAAGCGTATCAAACAAATGATGCAAGAAA
ACGAATAA

Upstream 100 bases:

>100_bases
CTATCCCCACCTTTTGCTTATCTTTTCTCAATTATATGATATAATAAAAAAGTTGTAATTAAAAGTGGGATTTTACTTAA
GAAAGAAGGAAACTATTTAT

Downstream 100 bases:

>100_bases
TTTAACATAATAAAAGAGAAGCTGAGCGATGAAAGTTGCTTAGCTTCTCTTTTGGCATATAATATTTGAAAAAGTGTTTA
AATGCTATTATTTCCTGTTA

Product: GTP-binding protein TypA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MTNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDERAMDSNDIERERGITILAKNTAVDYKGTRINILDTPG
HADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQ
LEFPVVYASAVNGTASLDPEKQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYNDYVGRIGIGRVFRGKMRVGDNV
SLIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDLIAVSGMEDINVGETVTPHDHQEALPVLRIDEPTLEMTFKVNNSP
FAGREGDFVTARQIQERLNQQLEIDVSLKVSNTDSPDTWVVAGRGELHLSILIENMRREGYELQVSKPQVIIKEIDGVMC
EPFERVQCEVPQENAGAVIESLGARKGEMVDMTTTDNGLTRLIFNVPARGMIGYTTEFMSMTRGYGIINHTFEEFRPRIK
AQIGGRRNGALISMDQGSASTYAILGLEDRGVNFMEPGTEVYEGMIVGEHNRENDLTVNITKTKHQTNVRSATKDQTQTM
NRPRILTLEEALQFINDDELVEVTPESIRLRKKILNKNVREKEAKRIKQMMQENE

Sequences:

>Translated_615_residues
MTNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDERAMDSNDIERERGITILAKNTAVDYKGTRINILDTPG
HADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQ
LEFPVVYASAVNGTASLDPEKQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYNDYVGRIGIGRVFRGKMRVGDNV
SLIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDLIAVSGMEDINVGETVTPHDHQEALPVLRIDEPTLEMTFKVNNSP
FAGREGDFVTARQIQERLNQQLEIDVSLKVSNTDSPDTWVVAGRGELHLSILIENMRREGYELQVSKPQVIIKEIDGVMC
EPFERVQCEVPQENAGAVIESLGARKGEMVDMTTTDNGLTRLIFNVPARGMIGYTTEFMSMTRGYGIINHTFEEFRPRIK
AQIGGRRNGALISMDQGSASTYAILGLEDRGVNFMEPGTEVYEGMIVGEHNRENDLTVNITKTKHQTNVRSATKDQTQTM
NRPRILTLEEALQFINDDELVEVTPESIRLRKKILNKNVREKEAKRIKQMMQENE
>Mature_614_residues
TNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDERAMDSNDIERERGITILAKNTAVDYKGTRINILDTPGH
ADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKALEQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQL
EFPVVYASAVNGTASLDPEKQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYNDYVGRIGIGRVFRGKMRVGDNVS
LIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDLIAVSGMEDINVGETVTPHDHQEALPVLRIDEPTLEMTFKVNNSPF
AGREGDFVTARQIQERLNQQLEIDVSLKVSNTDSPDTWVVAGRGELHLSILIENMRREGYELQVSKPQVIIKEIDGVMCE
PFERVQCEVPQENAGAVIESLGARKGEMVDMTTTDNGLTRLIFNVPARGMIGYTTEFMSMTRGYGIINHTFEEFRPRIKA
QIGGRRNGALISMDQGSASTYAILGLEDRGVNFMEPGTEVYEGMIVGEHNRENDLTVNITKTKHQTNVRSATKDQTQTMN
RPRILTLEEALQFINDDELVEVTPESIRLRKKILNKNVREKEAKRIKQMMQENE

Specific function: Not known; probably interacts with the ribosomes in a GTP dependent manner [H]

COG id: COG1217

COG function: function code T; Predicted membrane GTPase involved in stress response

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. TypA subfamily [H]

Homologues:

Organism=Homo sapiens, GI157426893, Length=315, Percent_Identity=32.3809523809524, Blast_Score=134, Evalue=2e-31,
Organism=Homo sapiens, GI94966754, Length=133, Percent_Identity=44.3609022556391, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI25306287, Length=467, Percent_Identity=27.8372591006424, Blast_Score=115, Evalue=1e-25,
Organism=Homo sapiens, GI25306283, Length=168, Percent_Identity=38.6904761904762, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19923640, Length=168, Percent_Identity=38.6904761904762, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI4503483, Length=153, Percent_Identity=37.2549019607843, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI18390331, Length=140, Percent_Identity=40.7142857142857, Blast_Score=104, Evalue=3e-22,
Organism=Homo sapiens, GI34147630, Length=308, Percent_Identity=32.4675324675325, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI310132016, Length=111, Percent_Identity=41.4414414414414, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310110807, Length=111, Percent_Identity=41.4414414414414, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI310123363, Length=111, Percent_Identity=41.4414414414414, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI217272892, Length=141, Percent_Identity=37.5886524822695, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI217272894, Length=141, Percent_Identity=37.5886524822695, Blast_Score=89, Evalue=1e-17,
Organism=Homo sapiens, GI94966752, Length=129, Percent_Identity=33.3333333333333, Blast_Score=82, Evalue=2e-15,
Organism=Homo sapiens, GI53729339, Length=186, Percent_Identity=33.8709677419355, Blast_Score=78, Evalue=3e-14,
Organism=Homo sapiens, GI53729337, Length=186, Percent_Identity=33.8709677419355, Blast_Score=78, Evalue=3e-14,
Organism=Escherichia coli, GI48994988, Length=597, Percent_Identity=54.4388609715243, Blast_Score=678, Evalue=0.0,
Organism=Escherichia coli, GI1788922, Length=526, Percent_Identity=28.5171102661597, Blast_Score=163, Evalue=2e-41,
Organism=Escherichia coli, GI1789738, Length=148, Percent_Identity=39.8648648648649, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1790835, Length=178, Percent_Identity=28.6516853932584, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1789737, Length=309, Percent_Identity=27.831715210356, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790412, Length=309, Percent_Identity=27.831715210356, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789559, Length=164, Percent_Identity=35.3658536585366, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17557151, Length=509, Percent_Identity=27.3084479371316, Blast_Score=149, Evalue=5e-36,
Organism=Caenorhabditis elegans, GI17556745, Length=449, Percent_Identity=28.0623608017817, Blast_Score=130, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17533571, Length=177, Percent_Identity=38.4180790960452, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI17506493, Length=165, Percent_Identity=33.9393939393939, Blast_Score=106, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI71988811, Length=134, Percent_Identity=34.3283582089552, Blast_Score=100, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71988819, Length=134, Percent_Identity=34.3283582089552, Blast_Score=99, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI17552882, Length=134, Percent_Identity=36.5671641791045, Blast_Score=96, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17556456, Length=305, Percent_Identity=26.8852459016393, Blast_Score=89, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI71994658, Length=156, Percent_Identity=38.4615384615385, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI25141371, Length=281, Percent_Identity=28.1138790035587, Blast_Score=75, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6323320, Length=525, Percent_Identity=28, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6324707, Length=153, Percent_Identity=40.5228758169935, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6320593, Length=153, Percent_Identity=40.5228758169935, Blast_Score=115, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324761, Length=276, Percent_Identity=30.0724637681159, Blast_Score=103, Evalue=8e-23,
Organism=Saccharomyces cerevisiae, GI6323098, Length=179, Percent_Identity=34.6368715083799, Blast_Score=98, Evalue=3e-21,
Organism=Saccharomyces cerevisiae, GI6322359, Length=149, Percent_Identity=38.255033557047, Blast_Score=95, Evalue=3e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=149, Percent_Identity=36.9127516778523, Blast_Score=94, Evalue=6e-20,
Organism=Saccharomyces cerevisiae, GI6324550, Length=146, Percent_Identity=31.5068493150685, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI78706572, Length=518, Percent_Identity=26.2548262548263, Blast_Score=123, Evalue=4e-28,
Organism=Drosophila melanogaster, GI28574573, Length=144, Percent_Identity=41.6666666666667, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI24582462, Length=181, Percent_Identity=37.0165745856354, Blast_Score=111, Evalue=2e-24,
Organism=Drosophila melanogaster, GI24585709, Length=157, Percent_Identity=35.6687898089172, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24585711, Length=155, Percent_Identity=36.1290322580645, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI24585713, Length=155, Percent_Identity=36.1290322580645, Blast_Score=108, Evalue=2e-23,
Organism=Drosophila melanogaster, GI21357743, Length=134, Percent_Identity=41.044776119403, Blast_Score=98, Evalue=2e-20,
Organism=Drosophila melanogaster, GI281363316, Length=271, Percent_Identity=29.520295202952, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI17864358, Length=271, Percent_Identity=29.520295202952, Blast_Score=96, Evalue=6e-20,
Organism=Drosophila melanogaster, GI221458488, Length=160, Percent_Identity=40.625, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI19921738, Length=302, Percent_Identity=27.4834437086093, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28572034, Length=165, Percent_Identity=35.7575757575758, Blast_Score=81, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR004161
- InterPro:   IPR009000
- InterPro:   IPR006298 [H]

Pfam domain/function: PF00679 EFG_C; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 69209; Mature: 69077

Theoretical pI: Translated: 4.66; Mature: 4.66

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDERAMDSNDIERERGITIL
CCCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHCCEEEE
AKNTAVDYKGTRINILDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKAL
EECCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQLEFPVVYASAVNGTASLDPE
HCCCCCEEEEECCCCCCCCCCCHHHHHHHHEEEECCCCCEEEEEEEEEEECCCCCCCCCC
KQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYNDYVGRIGIGRVFRGKMRVGDNV
CCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEECCEECCCCE
SLIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDLIAVSGMEDINVGETVTPHDHQEAL
EEEEECCCCCCEEEEEEEHHHCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCHHHCC
PVLRIDEPTLEMTFKVNNSPFAGREGDFVTARQIQERLNQQLEIDVSLKVSNTDSPDTWV
CEEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHCCCEEEEEEEEEECCCCCCCEEE
VAGRGELHLSILIENMRREGYELQVSKPQVIIKEIDGVMCEPFERVQCEVPQENAGAVIE
EECCCCEEEEEEEHHHHCCCCEEEECCCHHHHHHHCCCCCCCHHHHEEECCCCCCCHHHH
SLGARKGEMVDMTTTDNGLTRLIFNVPARGMIGYTTEFMSMTRGYGIINHTFEEFRPRIK
HHCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHH
AQIGGRRNGALISMDQGSASTYAILGLEDRGVNFMEPGTEVYEGMIVGEHNRENDLTVNI
HHCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHCCEEEECCCCCCCEEEEE
TKTKHQTNVRSATKDQTQTMNRPRILTLEEALQFINDDELVEVTPESIRLRKKILNKNVR
EECCCCCHHHHHCCHHHHHCCCCEEEEHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCHH
EKEAKRIKQMMQENE
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
TNKREDVRNIAIIAHVDHGKTTLVDELLKQSGIFRENEHVDERAMDSNDIERERGITIL
CCCHHCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCHHHCCEEEE
AKNTAVDYKGTRINILDTPGHADFGGEVERIMKMVDGVVLVVDAYEGTMPQTRFVLKKAL
EECCEEEECCCEEEEEECCCCCCCCHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHH
EQNLKPVVVVNKIDKPSARPEGVVDEVLDLFIELEANDEQLEFPVVYASAVNGTASLDPE
HCCCCCEEEEECCCCCCCCCCCHHHHHHHHEEEECCCCCEEEEEEEEEEECCCCCCCCCC
KQDDNLQSLYETIIDYVPAPIDNSDEPLQFQVALLDYNDYVGRIGIGRVFRGKMRVGDNV
CCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCEEECCEECCCCE
SLIKLDGTVKNFRVTKIFGYFGLKRLEIEEAQAGDLIAVSGMEDINVGETVTPHDHQEAL
EEEEECCCCCCEEEEEEEHHHCEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCHHHCC
PVLRIDEPTLEMTFKVNNSPFAGREGDFVTARQIQERLNQQLEIDVSLKVSNTDSPDTWV
CEEEECCCCEEEEEEECCCCCCCCCCCEEEHHHHHHHCCCEEEEEEEEEECCCCCCCEEE
VAGRGELHLSILIENMRREGYELQVSKPQVIIKEIDGVMCEPFERVQCEVPQENAGAVIE
EECCCCEEEEEEEHHHHCCCCEEEECCCHHHHHHHCCCCCCCHHHHEEECCCCCCCHHHH
SLGARKGEMVDMTTTDNGLTRLIFNVPARGMIGYTTEFMSMTRGYGIINHTFEEFRPRIK
HHCCCCCCEEEEEECCCCCEEEEEECCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCHHH
AQIGGRRNGALISMDQGSASTYAILGLEDRGVNFMEPGTEVYEGMIVGEHNRENDLTVNI
HHCCCCCCCCEEEECCCCCCEEEEEEECCCCCCCCCCCHHHHCCEEEECCCCCCCEEEEE
TKTKHQTNVRSATKDQTQTMNRPRILTLEEALQFINDDELVEVTPESIRLRKKILNKNVR
EECCCCCHHHHHCCHHHHHCCCCEEEEHHHHHHHCCCCCEEEECHHHHHHHHHHHCCCHH
EKEAKRIKQMMQENE
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]