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The map label for this gene is spxA

Identifier: 148267430

GI number: 148267430

Start: 1049974

End: 1050369

Strand: Direct

Name: spxA

Synonym: SaurJH9_0996

Alternate gene names: 148267430

Gene position: 1049974-1050369 (Clockwise)

Preceding gene: 148267428

Following gene: 148267431

Centisome position: 36.12

GC content: 32.58

Gene sequence:

>396_bases
ATGGTAACATTATTTACTTCACCAAGTTGCACATCTTGCCGTAAAGCGAAAGCATGGTTACAAGAACATGACATTCCGTA
TACGGAGCGTAATATTTTTTCTGAACATTTAACAATTGATGAAATTAAGCAAATATTAAAAATGACTGAAGACGGTACTG
ATGAAATCATTTCTACACGTTCTAAAACATACCAAAAATTAAATGTTGATATTGATTCACTACCATTACAAGACTTATAT
TCAATCATTCAAGATAATCCTGGCTTATTACGTCGTCCAATTATTTTAGATAATAAACGACTACAAGTTGGTTATAATGA
GGACGAGATTCGACGTTTCTTACCTAGAAAAGTTCGTACGTTCCAATTACAAGAAGCACAACGTATGGTTGACTAA

Upstream 100 bases:

>100_bases
ATAGTAACGATTAAGAATTTTAGAAAAAAATGTTTTTTCTTGATCTATAACTAAATTTTAAGCAATGAATTTTATTCATT
CAAATAGGAGAGTGAGATGT

Downstream 100 bases:

>100_bases
TAACCATTTAACTATGTGTCATACTTTACTAAAAGATATGTCAAGCAACACTATTTCTATAGTGTTGCTTTTTTGGTTTT
AATTTTACAATAATTGCTTA

Product: Spx family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTRSKTYQKLNVDIDSLPLQDLY
SIIQDNPGLLRRPIILDNKRLQVGYNEDEIRRFLPRKVRTFQLQEAQRMVD

Sequences:

>Translated_131_residues
MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTRSKTYQKLNVDIDSLPLQDLY
SIIQDNPGLLRRPIILDNKRLQVGYNEDEIRRFLPRKVRTFQLQEAQRMVD
>Mature_131_residues
MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTRSKTYQKLNVDIDSLPLQDLY
SIIQDNPGLLRRPIILDNKRLQVGYNEDEIRRFLPRKVRTFQLQEAQRMVD

Specific function: Interferes with activator-stimulated transcription by interaction with the RNA polymerase alpha-CTD. May function to globally reduce transcription of genes involved in growth- and development-promoting processes and to increase transcription of genes invo

COG id: COG1393

COG function: function code P; Arsenate reductase and related proteins, glutaredoxin family

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArsC family. Spx subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SPX_STAAC (Q5HH87)

Other databases:

- EMBL:   CP000046
- RefSeq:   YP_185870.1
- ProteinModelPortal:   Q5HH87
- SMR:   Q5HH87
- STRING:   Q5HH87
- EnsemblBacteria:   EBSTAT00000009313
- GeneID:   3236118
- GenomeReviews:   CP000046_GR
- KEGG:   sac:SACOL1002
- TIGR:   SACOL1002
- eggNOG:   COG1393
- GeneTree:   EBGT00050000024542
- HOGENOM:   HBG734370
- OMA:   RRMQVGY
- ProtClustDB:   PRK01655
- BioCyc:   SAUR93062:SACOL1002-MONOMER
- GO:   GO:0005737
- GO:   GO:0006350
- HAMAP:   MF_01132
- InterPro:   IPR006660
- InterPro:   IPR012336
- InterPro:   IPR012335
- InterPro:   IPR006504
- Gene3D:   G3DSA:3.40.30.10
- TIGRFAMs:   TIGR01617

Pfam domain/function: PF03960 ArsC; SSF52833 Thiordxn-like_fd

EC number: NA

Molecular weight: Translated: 15441; Mature: 15441

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS51353 ARSC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTR
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
SKTYQKLNVDIDSLPLQDLYSIIQDNPGLLRRPIILDNKRLQVGYNEDEIRRFLPRKVRT
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCEECCEEECCCEEEECCCHHHHHHHHHHHHHH
FQLQEAQRMVD
HHHHHHHHCCC
>Mature Secondary Structure
MVTLFTSPSCTSCRKAKAWLQEHDIPYTERNIFSEHLTIDEIKQILKMTEDGTDEIISTR
CEEEECCCCCHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHH
SKTYQKLNVDIDSLPLQDLYSIIQDNPGLLRRPIILDNKRLQVGYNEDEIRRFLPRKVRT
HHHHHHHCCCCCCCCHHHHHHHHCCCCCCEECCEEECCCEEEECCCHHHHHHHHHHHHHH
FQLQEAQRMVD
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA