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The map label for this gene is dltA

Identifier: 148267366

GI number: 148267366

Start: 977396

End: 978853

Strand: Direct

Name: dltA

Synonym: SaurJH9_0932

Alternate gene names: 148267366

Gene position: 977396-978853 (Clockwise)

Preceding gene: 148267365

Following gene: 148267367

Centisome position: 33.63

GC content: 34.22

Gene sequence:

>1458_bases
ATGACAGATATTATTAACAAGCTGCAAGCGTTTGCGGATGCAAATCCACAAAGCATTGCTGTTAGACACACAACTGATGA
ATTAACTTATCAACAGTTAATGGATGAGTCTAGTAAATTAGCACATCGATTACAAGGTAGTAAGAAACCGATGATTTTAT
TCGGTCACATGTCACCATATATGATTGTTGGGATGATTGGTGCCATTAAAGCAGGATGTGGATATGTACCTGTAGACACT
TCAATTCCTGAAGACCGTATTAAAATGATTATTAACAAGGTTCAACCAGAGTTTGTATTTAATACGACTGATGAATCATT
TGAAAGTTTAGAAGGCGAAGTATTTACAATTGAAGATATTAAAACATCTCAAGACCCAGTAATTTTTGATAGTCAGATTA
AAGATAACGACACAGTATACACAATCTTTACATCTGGTTCTACTGGGGAACCTAAAGGTGTTCAAATTGAATATGCAAGT
TTAGTTCAATTTACTGAGTGGATGTTAGAACTTAATAAATCAGGAAATAAACAACAATGGCTTAACCAAGCGCCATTTTC
ATTTGATTTATCTGTAATGGCTATTTATCCATGTTTAGCATCAGGCGGTACATTAAATCTTGTAGATAAAAACATGATTA
ATAAACCTAAATTATTAAATGAAATGCTAACAGCAACACCGATTAACATTTGGGTATCAACACCATCATTTATGGAAATG
TGTTTATTATTACCAACGCTTAATGAAGAACAATATGGTAGTCTTAACGAATTCTTCTTCTGTGGTGAAATTCTACCTCA
CAGAGCAGCAAAAGCGTTAGTGAGCCGTTTCCCAAGTGCGACGATTTACAACACATATGGTCCAACTGAAGCTACGGTAG
CAGTTACAAGTATTCAAATTACACAAGAAATCTTAGATCAATATCCGACATTACCTGTTGGCGTTGAAAGACTAGGCGCA
AGATTATCTACTACAGATGACGGTGAACTTGTTATTGAAGGTCAAAGTGTAAGTTTAGGATACTTAAAAAATGACCAAAA
AACAGCTGAAGTATTTAATTTCGATGACGGTATTCGTACATATCACACTGGTGATAAAGCGAAGTTTGAAAATGGTCAAT
GGTTCATTCAAGGTCGTATTGATTTCCAAATCAAATTGAATGGCTACAGAATGGAATTAGAAGAAATTGAAACACAATTA
CGCCAGTCTGAGTTCGTAAAAGAAGCGATTGTTGTACCTGTATATAAAAATGATAAAGTTATTCATTTAATTGGTGCAAT
TGTGCCAACGACTGAAGTTACGGACAATGCAGAAATGACTAAAAATATTAAAAATGACTTGAAATCACGCTTACCAGAGT
ATATGATTCCTAGAAAGTTTGAATGGATGGAACAATTGCCATTGACTTCAAATGGTAAAATTGACAGAAAGAAAATTGCA
GAGGTAATTAACGGATGA

Upstream 100 bases:

>100_bases
ATTGTATTTGGCAATATTTATTACTTTATATTTAATTTATGGCAGTGGCGACACACACAATAACTTCATTTATAATGAGT
TCTAATGAGGGAGACTTAAT

Downstream 100 bases:

>100_bases
TTCCATATGGTGATTTTACATTCTTCTTAATTGCTTTAATTGCATTATTACCAGTCATTATACTTGGATTTTTAGGTAAG
CGAAGTTACATTTATAATGG

Product: D-alanine--poly(phosphoribitol) ligase subunit 1

Products: NA

Alternate protein names: D-alanine-D-alanyl carrier protein ligase; DCL; D-alanine-activating enzyme; DAE

Number of amino acids: Translated: 485; Mature: 484

Protein sequence:

>485_residues
MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDT
SIPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYAS
LVQFTEWMLELNKSGNKQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEM
CLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVSRFPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERLGA
RLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQL
RQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIA
EVING

Sequences:

>Translated_485_residues
MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDT
SIPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYAS
LVQFTEWMLELNKSGNKQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEM
CLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVSRFPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERLGA
RLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQL
RQSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIA
EVING
>Mature_484_residues
TDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPYMIVGMIGAIKAGCGYVPVDTS
IPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDIKTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYASL
VQFTEWMLELNKSGNKQQWLNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEMC
LLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVSRFPSATIYNTYGPTEATVAVTSIQITQEILDQYPTLPVGVERLGAR
LSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRTYHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQLR
QSEFVKEAIVVPVYKNDKVIHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIAE
VING

Specific function: Involved in the biosynthesis of D-alanyl-lipoteichoic acid (LTA). Catalyzes an ATP-dependent two-step reaction where it forms a high energy D-alanyl AMP intermediate and transfers the alanyl residues from AMP to Dcp

COG id: COG1020

COG function: function code Q; Non-ribosomal peptide synthetase modules and related proteins

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent AMP-binding enzyme family. DltA subfamily

Homologues:

Organism=Homo sapiens, GI45580730, Length=358, Percent_Identity=25.6983240223464, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI156151445, Length=392, Percent_Identity=26.530612244898, Blast_Score=79, Evalue=9e-15,
Organism=Homo sapiens, GI115511026, Length=373, Percent_Identity=24.9329758713137, Blast_Score=69, Evalue=8e-12,
Organism=Escherichia coli, GI1786801, Length=451, Percent_Identity=27.0509977827051, Blast_Score=144, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI17556356, Length=501, Percent_Identity=26.1477045908184, Blast_Score=97, Evalue=2e-20,
Organism=Caenorhabditis elegans, GI32563687, Length=420, Percent_Identity=22.8571428571429, Blast_Score=90, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17558820, Length=434, Percent_Identity=22.3502304147465, Blast_Score=85, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=475, Percent_Identity=22.7368421052632, Blast_Score=79, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI17531443, Length=365, Percent_Identity=25.2054794520548, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17557194, Length=371, Percent_Identity=24.2587601078167, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560308, Length=371, Percent_Identity=25.0673854447439, Blast_Score=68, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319591, Length=582, Percent_Identity=23.3676975945017, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6319699, Length=372, Percent_Identity=24.7311827956989, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24648676, Length=455, Percent_Identity=25.2747252747253, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI18859661, Length=521, Percent_Identity=22.8406909788868, Blast_Score=77, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DLTA_STAA1 (A7X0D6)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441517.1
- ProteinModelPortal:   A7X0D6
- STRING:   A7X0D6
- EnsemblBacteria:   EBSTAT00000004459
- GeneID:   5560920
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0927
- eggNOG:   COG1020
- GeneTree:   EBGT00050000024490
- HOGENOM:   HBG320748
- OMA:   FICTEEL
- ProtClustDB:   PRK04813
- BioCyc:   SAUR418127:SAHV_0927-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00593
- InterPro:   IPR010071
- InterPro:   IPR000873
- InterPro:   IPR010072
- PANTHER:   PTHR11968:SF34
- TIGRFAMs:   TIGR01733
- TIGRFAMs:   TIGR01734

Pfam domain/function: PF00501 AMP-binding

EC number: =6.1.1.13

Molecular weight: Translated: 54645; Mature: 54514

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00455 AMP_BINDING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPY
CHHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCHHHHHHHHHCCCCCCEEEEECCCHH
MIVGMIGAIKAGCGYVPVDTSIPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDI
HHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEEEECC
KTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYASLVQFTEWMLELNKSGNKQQW
CCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHH
LNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEM
HHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCHHHHHH
CLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVSRFPSATIYNTYGPTEATVAVTSIQI
HHHCCCCCCHHCCCCHHEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEHHHH
TQEILDQYPTLPVGVERLGARLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT
HHHHHHHCCCCCCCHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHEECCCCCCCE
YHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKV
EECCCCCEECCCCEEEEEEEEEEEEECCEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCE
IHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIA
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCHHHHHHHCCCCCCCCCCHHHHH
EVING
HHHCC
>Mature Secondary Structure 
TDIINKLQAFADANPQSIAVRHTTDELTYQQLMDESSKLAHRLQGSKKPMILFGHMSPY
HHHHHHHHHHHCCCCCEEEEEECCHHHHHHHHHCHHHHHHHHHCCCCCCEEEEECCCHH
MIVGMIGAIKAGCGYVPVDTSIPEDRIKMIINKVQPEFVFNTTDESFESLEGEVFTIEDI
HHHHHHHHHHCCCCEECCCCCCCHHHHHHHHHHCCCCEEEECCCHHHHHCCCCEEEEECC
KTSQDPVIFDSQIKDNDTVYTIFTSGSTGEPKGVQIEYASLVQFTEWMLELNKSGNKQQW
CCCCCCEEEECCCCCCCEEEEEEECCCCCCCCCEEEEHHHHHHHHHHHHHHCCCCCHHHH
LNQAPFSFDLSVMAIYPCLASGGTLNLVDKNMINKPKLLNEMLTATPINIWVSTPSFMEM
HHCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCHHHHHH
CLLLPTLNEEQYGSLNEFFFCGEILPHRAAKALVSRFPSATIYNTYGPTEATVAVTSIQI
HHHCCCCCCHHCCCCHHEEEHHHHHHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEHHHH
TQEILDQYPTLPVGVERLGARLSTTDDGELVIEGQSVSLGYLKNDQKTAEVFNFDDGIRT
HHHHHHHCCCCCCCHHHHCCCCCCCCCCEEEEECCCEEEEEECCCCHHHHEECCCCCCCE
YHTGDKAKFENGQWFIQGRIDFQIKLNGYRMELEEIETQLRQSEFVKEAIVVPVYKNDKV
EECCCCCEECCCCEEEEEEEEEEEEECCEEEEHHHHHHHHHHHHHHHHHEEEEEECCCCE
IHLIGAIVPTTEVTDNAEMTKNIKNDLKSRLPEYMIPRKFEWMEQLPLTSNGKIDRKKIA
EEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCHHCCCCHHHHHHHCCCCCCCCCCHHHHH
EVING
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA