Definition Staphylococcus aureus subsp. aureus JH9, complete genome.
Accession NC_009487
Length 2,906,700

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The map label for this gene is 148267248

Identifier: 148267248

GI number: 148267248

Start: 893246

End: 894748

Strand: Direct

Name: 148267248

Synonym: SaurJH9_0813

Alternate gene names: NA

Gene position: 893246-894748 (Clockwise)

Preceding gene: 148267247

Following gene: 148267249

Centisome position: 30.73

GC content: 29.61

Gene sequence:

>1503_bases
TTGAAAAATAAATTGCTAGTTTTATCATTGGGAGCATTATGTGTATCACAAATTTGGGAAAGTAATCATGCGAGTGCAGT
GGTTTCTGGGGAGAAGAATCCATATGTATCAAAAGCTTTAGAATTGAAAGATAAAAGTAATAAATCCAATTCTTACGAAA
ATTATAGAGATAGTTTAGAAAGTTTGATTTCATCATTATCTTTTGCTGATTATGAAAAATATGAAGAGCCAGAATATGAA
AAGGCTGTAAAAAAATATCAACAAAAATTTATGGCTGAAGATGATGCATTAAAAAATTTTTTAAATGAAGAAAAGAAGAT
AAAAAATGCAGATATTAGCAGAAAATCGAATGATTTATTAGGTTTAACACATGAAAGATATTCTTATATTTTTGATACAT
TAAAGAAAAATAAACAAGAGTTTTTAAAAGATATTGAAGAAATACAACTGAAAAATAGTGATTTAAAGGACTTTAACAAT
ACAGAGCAACATAATGCCGACGTAGAAATAAACAATTTAGAAAATAAAGTATTAATGGTAGGGTATACATTCTATAATAC
AAATAAGGACGAAGTTGAAGAATTATATAGTGAGTTAGATTTGATTGTTGGAGAAGTTCAAGATAAGTCGGATAAAAAAA
GAGCAGTAAATCAAAGGATGTTAAATAGAAAAAAAGAGGATTTAGAATTTATTATAGATAAATTTTTTAAAAAAATTCAA
CAAGAACGTCCAGAGAGTATACCAGCATTAACTAGTGAAAAAAATCATAATCAGACTATGGCATTAAAGTTAAAAGCAGA
TACAGAAGCTGCTAAAAATGACGTATCAAAAAGAAGTAAAAGAAGTTTAAATACTCAAAATAATAAATCTACAACACAAG
AAATTTCTGAAGAACAAAAAGCTGAATATCAAAGAAAGTCAGAGGCATTAAAAGAAAGATTTATAAACAGACAAAAATCT
AAAAATGAGTCTGTGGTTTCACTAATCGATGACGAAGACGACAACGAAAACGACAGGCAACTTGTGGTTTCTGCGCCATC
AAAGAAACCAACAACACCGACTACATATACTGAAACAACGACTCAGGTACCAATGCCTACAGTTGAGCGTCAAACTCAGC
AACAAATCGTTTACAAAACACCAAAACCATTAGCTGGATTAAATGGTGAAAGTCATGATTTCACAACAACGCATCAATCA
CCAACAACTTCAAATCATACGCATAATAATGTTGTTGAATTTGAAGAAACGTCTGCTTTACCTGGTAGAAAATCAGGATC
ACTGGTTGGTATAAGTCAAATTGATTCTTCTCATCTAACTGAACGTGAGAAGCGTGTAATCAAGCGTGAACACGTTAGAG
AAGCTCAAAAGTTAGTTGATAATTATAAAGATACACATAGTTATAAAGACCGATTAAATGCACAACAAAAAGTAAATACT
TTAAGTGAAGGTCATCAAAAACGTTTTAATAAACAAATCAATAAAGTATACAATGGCAAATAA

Upstream 100 bases:

>100_bases
TTAATTATTTTAAAAAGGTAGATGTTATATAATTTGGCTTGGCGAAAAAATAGGGTGTAAGGTAGGTTGTTAATTAGGGA
AAATTAAGGAGAAAATACAG

Downstream 100 bases:

>100_bases
TATTAATGCATGGCTGCAAAGCAAATAATGAGTTTGTCGTAAAAATAACAACATTTTAAACTAGCAATAAATAATATCAA
AGTCATCATTTCAATGATGC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKDKSNKSNSYENYRDSLESLISSLSFADYEKYEEPEYE
KAVKKYQQKFMAEDDALKNFLNEEKKIKNADISRKSNDLLGLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNN
TEQHNADVEINNLENKVLMVGYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQRMLNRKKEDLEFIIDKFFKKIQ
QERPESIPALTSEKNHNQTMALKLKADTEAAKNDVSKRSKRSLNTQNNKSTTQEISEEQKAEYQRKSEALKERFINRQKS
KNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETTTQVPMPTVERQTQQQIVYKTPKPLAGLNGESHDFTTTHQS
PTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRLNAQQKVNT
LSEGHQKRFNKQINKVYNGK

Sequences:

>Translated_500_residues
MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKDKSNKSNSYENYRDSLESLISSLSFADYEKYEEPEYE
KAVKKYQQKFMAEDDALKNFLNEEKKIKNADISRKSNDLLGLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNN
TEQHNADVEINNLENKVLMVGYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQRMLNRKKEDLEFIIDKFFKKIQ
QERPESIPALTSEKNHNQTMALKLKADTEAAKNDVSKRSKRSLNTQNNKSTTQEISEEQKAEYQRKSEALKERFINRQKS
KNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETTTQVPMPTVERQTQQQIVYKTPKPLAGLNGESHDFTTTHQS
PTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRLNAQQKVNT
LSEGHQKRFNKQINKVYNGK
>Mature_500_residues
MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKDKSNKSNSYENYRDSLESLISSLSFADYEKYEEPEYE
KAVKKYQQKFMAEDDALKNFLNEEKKIKNADISRKSNDLLGLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNN
TEQHNADVEINNLENKVLMVGYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQRMLNRKKEDLEFIIDKFFKKIQ
QERPESIPALTSEKNHNQTMALKLKADTEAAKNDVSKRSKRSLNTQNNKSTTQEISEEQKAEYQRKSEALKERFINRQKS
KNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETTTQVPMPTVERQTQQQIVYKTPKPLAGLNGESHDFTTTHQS
PTTSNHTHNNVVEFEETSALPGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRLNAQQKVNT
LSEGHQKRFNKQINKVYNGK

Specific function: Staphylocoagulase is an extracellular protein which specifically forms a complex with human prothrombin. This complex named staphylothrombin can clot fibrinogen without any proteolytic cleavage of prothrombin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the staphylocoagulase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014874
- InterPro:   IPR001443 [H]

Pfam domain/function: PF08764 Coagulase; PF04022 Staphylcoagulse [H]

EC number: NA

Molecular weight: Translated: 57794; Mature: 57794

Theoretical pI: Translated: 7.86; Mature: 7.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKDKSNKSNSYENYRDSLE
CCCCEEEEHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
SLISSLSFADYEKYEEPEYEKAVKKYQQKFMAEDDALKNFLNEEKKIKNADISRKSNDLL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNNTEQHNADVEINNLENKVLMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
GYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQRMLNRKKEDLEFIIDKFFKKIQ
EEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QERPESIPALTSEKNHNQTMALKLKADTEAAKNDVSKRSKRSLNTQNNKSTTQEISEEQK
HHCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AEYQRKSEALKERFINRQKSKNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETT
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
TQVPMPTVERQTQQQIVYKTPKPLAGLNGESHDFTTTHQSPTTSNHTHNNVVEFEETSAL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHCCCC
PGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRLNAQQKVNT
CCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEGHQKRFNKQINKVYNGK
HHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKNKLLVLSLGALCVSQIWESNHASAVVSGEKNPYVSKALELKDKSNKSNSYENYRDSLE
CCCCEEEEHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCHHHHHHHHH
SLISSLSFADYEKYEEPEYEKAVKKYQQKFMAEDDALKNFLNEEKKIKNADISRKSNDLL
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
GLTHERYSYIFDTLKKNKQEFLKDIEEIQLKNSDLKDFNNTEQHNADVEINNLENKVLMV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEE
GYTFYNTNKDEVEELYSELDLIVGEVQDKSDKKRAVNQRMLNRKKEDLEFIIDKFFKKIQ
EEEEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
QERPESIPALTSEKNHNQTMALKLKADTEAAKNDVSKRSKRSLNTQNNKSTTQEISEEQK
HHCCCCCCCCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AEYQRKSEALKERFINRQKSKNESVVSLIDDEDDNENDRQLVVSAPSKKPTTPTTYTETT
HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCC
TQVPMPTVERQTQQQIVYKTPKPLAGLNGESHDFTTTHQSPTTSNHTHNNVVEFEETSAL
CCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEHHCCCC
PGRKSGSLVGISQIDSSHLTEREKRVIKREHVREAQKLVDNYKDTHSYKDRLNAQQKVNT
CCCCCCCEEEHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LSEGHQKRFNKQINKVYNGK
HHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2587230; 3941089 [H]