Click here to switch to the map view.

The map label for this gene is rnr [H]

Identifier: 148267240

GI number: 148267240

Start: 882672

End: 885044

Strand: Direct

Name: rnr [H]

Synonym: SaurJH9_0805

Alternate gene names: 148267240

Gene position: 882672-885044 (Clockwise)

Preceding gene: 148267239

Following gene: 148267241

Centisome position: 30.37

GC content: 34.22

Gene sequence:

>2373_bases
ATGAATTTAAAGCAATCAATAGAAGAGATTATTAATCAACCTGAATATGAACCTATGTCAGTGTCAGATTTTCAAGATGC
ATTAGGTTTAAGTAGTGCCGACTCATTTAGAGATTTAATTAAGGTGCTCGTAGAATTAGAACAATCAGGATTAATTGAAC
GTACAAAAACAGACAGATATCAAAAAAAGCATAGTTCAAAAGGTCATTCAAAATTGATAAAGGGAACGTTAAGTCAAAAT
AAAAAAGGCTTTGCATTCTTAAGACCTGAAGATGAGGATATGGAAGATATATTTATTCCCCCAACAAAAATTAATCGTGC
CTTAGATGGAGATACTGTAATTGTAGAAATACATCAATCTAAAGGTGAACATAAAGGTAAAATTGAAGGGGAAGTTAAGT
CGATTGAGAAGCATTCAGTAACTCAAGTTGTTGGTACGTATAGTGAAGCTAGACATTTCGGATTTGTTATTCCAGATGAT
AAACGTATTATGCAAGATATTTTCATTCCTAAAGGACAAAGTTTAGGTGCAGTAGATGGGCATAAGGTACTTGTTCAAAT
TACTAAATATGCTGATGGTTCAGATAATCCAGAAGGACATATTTCTGCTATTTTAGGACATAAAAATGATCCTGGCGTAG
ATATTTTATCTATTATCTATCAACATGGCATAGAAATTGAATTTCCTGATGAAGTGTTACAAGAAGCTGAAGCAGTACCT
GATCATATTGAAAATACTGAAATTAAAGGCCGTCATGATTTACGTGATGAATTGACAATCACAATTGATGGTGCTGATGC
TAAAGACTTAGATGACGCAATTAGTGTTAAAAAGTTAGCGAACGGTAATACGCAGTTGACTGTAAGTATTGCTGATGTCA
GTTATTATGTAACTGAAGATTCAGCTTTAGATAAAGAAGCTTATGATAGAGCGACAAGTGTATATCTTGTTGACCGTGTG
ATTCCGATGATTCCACATCGATTAAGCAATGGTATTTGTTCATTAAATCCTCATGTTGATCGTTTAACGTTAAGCTGTCG
CATGGAAATCGATGCTAGTGGTCGCGTTGTTAAACATGAAATTTTTGATAGTGTTATACATTCTGATTATCGAATGACGT
ATGATGCGGTAAATCAGATTATTACTGAAAAGGATCCTAACATTCGCGAACAATATAAAGAAATTACGCCTATGTTAGAT
TTAGCACAAGATTTATCTAATCGTTTGATTCAAATGAGAAAACGACGTGGTGAAATCGATTTTGATATTAGTGAAGCAAA
AGTATTAGTTAACGAAGTCGGTATACCAACAGATGTTCAATTAAGACAACGTGGCGAGGGTGAACGTCTAATTGAATCAT
TTATGTTAATTGCAAATGAAACAGTTGCTGAACATTTTAGTAAGTTAAATGTACCTTTTATTTACCGAGTGCATGAGCAA
CCTAAATCAGATCGCTTAAGACAATTCTTTGATTTTATTACAAACTTTGGCATCATGATTAAGGGCACTGGCGAAGATAT
TCATCCAACAACACTTCAAAAGGTTCAAGAAGAAGTAGAAGGTCGACCTGAACAAATGGTCATTTCAACAATGATGTTAC
GTTCAATGCAACAAGCGCATTATGATGATGTGAACTTGGGACATTTTGGCTTATCAGCTGAATATTATACGCATTTTACA
TCACCAATTAGACGTTATCCTGATTTAACAGTTCATCGTTTAATCCGTAAGTATTTAATTGAGAAATCAATGGATAACAA
AGAAGTGAAGCGTTGGGAAGACAAATTGCCTGAGTTAGCTGAACATACTTCTAAACGTGAACGTCGTGCTATTGAGGCAG
AACGTGATACTGATGAATTGAAAAAAGCAGAATATATGATTCAACATATTGGTGATGAATTTGAAGGTATTGTCAGCTCA
GTAGCTAACTTCGGTATGTTCATTGAATTGCCAAATACGATAGAAGGTATGGTTCATATTGCGAATATGACTGATGATTA
TTACCGTTTTGAAGAGCGTCAAATGGCATTAATTGGTGAGCGTCAAGCTAAAGTATTTAGAATTGGTGACACAGTTAAGG
TTAAAGTGACGCATGTTGATGTAGATGAACGATTAATTGATTTTCAAATTGTTGGAATGCCTTTACCTAAAAATGACCGC
TCACAGCGACCAGCAAGAGGTAAAACGATTCAAGCTAAAACGCGTGGCAAATCTTTAGATAAATCGAAATCTGATGATAA
GGGTCGTAAGAAAAAAGGTAAGCAACGTAAAGGTAAAAACCAACGTAATAATGATAAATCAGGTAATAGTAAGCATAAGC
CATTTTATAAAGATAAAAGTGTGAAAAAGAAAGCACGTCGTAAGAAAAAATAA

Upstream 100 bases:

>100_bases
TAAAGAAAAAGAACAAGTATTTGAAGATATTTATCAATTTTTAGAGTCATTAGACTGGTCAGAATAAAAAGAGATTTTAA
CATTAGAAAGGAGGGGCATA

Downstream 100 bases:

>100_bases
GCAGCAATGAGGTGAGTATGAATGGCTAAGAAGAAATCACCAGGTACATTAGCGGAAAATCGTAAAGCAAGACATGATTA
TAATATTGAAGATACGATTG

Product: ribonuclease R

Products: NA

Alternate protein names: RNase R; VacB protein homolog [H]

Number of amino acids: Translated: 790; Mature: 790

Protein sequence:

>790_residues
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRYQKKHSSKGHSKLIKGTLSQN
KKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDD
KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEAVP
DHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRV
IPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLD
LAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEVGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLNVPFIYRVHEQ
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFT
SPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSS
VANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
SQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKSVKKKARRKKK

Sequences:

>Translated_790_residues
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRYQKKHSSKGHSKLIKGTLSQN
KKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDD
KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEAVP
DHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRV
IPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLD
LAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEVGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLNVPFIYRVHEQ
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFT
SPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSS
VANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
SQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKSVKKKARRKKK
>Mature_790_residues
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRYQKKHSSKGHSKLIKGTLSQN
KKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQSKGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDD
KRIMQDIFIPKGQSLGAVDGHKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEAVP
DHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTEDSALDKEAYDRATSVYLVDRV
IPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHEIFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLD
LAQDLSNRLIQMRKRRGEIDFDISEAKVLVNEVGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLNVPFIYRVHEQ
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAHYDDVNLGHFGLSAEYYTHFT
SPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELAEHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSS
VANFGMFIELPNTIEGMVHIANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
SQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKSVKKKARRKKK

Specific function: 3'-5'exoribonuclease that participates in an essential cell function. Acts nonspecifically on poly(A), poly(U) and ribosomal RNAs [H]

COG id: COG0557

COG function: function code K; Exoribonuclease R

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 S1 motif domain [H]

Homologues:

Organism=Homo sapiens, GI134288890, Length=424, Percent_Identity=32.0754716981132, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI190014625, Length=631, Percent_Identity=28.5261489698891, Blast_Score=188, Evalue=1e-47,
Organism=Homo sapiens, GI190014623, Length=631, Percent_Identity=28.5261489698891, Blast_Score=188, Evalue=2e-47,
Organism=Homo sapiens, GI19115966, Length=670, Percent_Identity=26.2686567164179, Blast_Score=167, Evalue=4e-41,
Organism=Homo sapiens, GI219521928, Length=670, Percent_Identity=26.2686567164179, Blast_Score=167, Evalue=5e-41,
Organism=Homo sapiens, GI156105695, Length=217, Percent_Identity=30.8755760368664, Blast_Score=84, Evalue=8e-16,
Organism=Homo sapiens, GI156105693, Length=211, Percent_Identity=30.3317535545024, Blast_Score=80, Evalue=1e-14,
Organism=Escherichia coli, GI87082383, Length=648, Percent_Identity=37.037037037037, Blast_Score=445, Evalue=1e-126,
Organism=Escherichia coli, GI1787542, Length=602, Percent_Identity=25.5813953488372, Blast_Score=155, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI17553506, Length=435, Percent_Identity=31.7241379310345, Blast_Score=180, Evalue=3e-45,
Organism=Caenorhabditis elegans, GI212645896, Length=626, Percent_Identity=26.1980830670927, Blast_Score=156, Evalue=5e-38,
Organism=Saccharomyces cerevisiae, GI6324552, Length=511, Percent_Identity=28.9628180039139, Blast_Score=184, Evalue=5e-47,
Organism=Saccharomyces cerevisiae, GI6320499, Length=410, Percent_Identity=23.4146341463415, Blast_Score=91, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6323943, Length=364, Percent_Identity=23.3516483516484, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24649634, Length=658, Percent_Identity=28.1155015197568, Blast_Score=196, Evalue=7e-50,
Organism=Drosophila melanogaster, GI24654592, Length=424, Percent_Identity=29.4811320754717, Blast_Score=165, Evalue=1e-40,
Organism=Drosophila melanogaster, GI19922976, Length=424, Percent_Identity=29.4811320754717, Blast_Score=164, Evalue=2e-40,
Organism=Drosophila melanogaster, GI24654597, Length=424, Percent_Identity=29.4811320754717, Blast_Score=164, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR003029
- InterPro:   IPR022967
- InterPro:   IPR013223
- InterPro:   IPR001900
- InterPro:   IPR022966
- InterPro:   IPR004476
- InterPro:   IPR011805 [H]

Pfam domain/function: PF08206 OB_RNB; PF00773 RNB; PF00575 S1 [H]

EC number: 3.1.-.- [C]

Molecular weight: Translated: 90420; Mature: 90420

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS50126 S1 ; PS01175 RIBONUCLEASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRY
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QKKHSSKGHSKLIKGTLSQNKKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQS
HHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEECCCHHHHHCCCCCEEEEEEECC
KGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDDKRIMQDIFIPKGQSLGAVDG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
HKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEAVP
CEEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEECCHHHHHHHHHCC
DHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTED
HHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEEECC
SALDKEAYDRATSVYLVDRVIPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEEEEECCCCCCHHHH
IFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLDLAQDLSNRLIQMRKRRGEID
HHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDISEAKVLVNEVGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLNVPFIYRVHEQ
CCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAH
CCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
YDDVNLGHFGLSAEYYTHFTSPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCHHHHHEEE
ANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
ECCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEECCCHHEEEEEEEECCCCCCCC
SQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKS
CCCCCCCCEEEEHHCCCCCCCCCCCCHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCHH
VKKKARRKKK
HHHHHHHCCC
>Mature Secondary Structure
MNLKQSIEEIINQPEYEPMSVSDFQDALGLSSADSFRDLIKVLVELEQSGLIERTKTDRY
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHH
QKKHSSKGHSKLIKGTLSQNKKGFAFLRPEDEDMEDIFIPPTKINRALDGDTVIVEIHQS
HHHHCCCCHHHHHHHHHCCCCCCEEEECCCCCCCCCEECCCHHHHHCCCCCEEEEEEECC
KGEHKGKIEGEVKSIEKHSVTQVVGTYSEARHFGFVIPDDKRIMQDIFIPKGQSLGAVDG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCCCCCCCCCCCCC
HKVLVQITKYADGSDNPEGHISAILGHKNDPGVDILSIIYQHGIEIEFPDEVLQEAEAVP
CEEEEEEEECCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCEECCHHHHHHHHHCC
DHIENTEIKGRHDLRDELTITIDGADAKDLDDAISVKKLANGNTQLTVSIADVSYYVTED
HHCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCCEEEEEEEEEEEEEECC
SALDKEAYDRATSVYLVDRVIPMIPHRLSNGICSLNPHVDRLTLSCRMEIDASGRVVKHE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCEEEEEEEEEECCCCCCHHHH
IFDSVIHSDYRMTYDAVNQIITEKDPNIREQYKEITPMLDLAQDLSNRLIQMRKRRGEID
HHHHHHHCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
FDISEAKVLVNEVGIPTDVQLRQRGEGERLIESFMLIANETVAEHFSKLNVPFIYRVHEQ
CCHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
PKSDRLRQFFDFITNFGIMIKGTGEDIHPTTLQKVQEEVEGRPEQMVISTMMLRSMQQAH
CCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHC
YDDVNLGHFGLSAEYYTHFTSPIRRYPDLTVHRLIRKYLIEKSMDNKEVKRWEDKLPELA
CCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
EHTSKRERRAIEAERDTDELKKAEYMIQHIGDEFEGIVSSVANFGMFIELPNTIEGMVHI
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHCCEEEECCCHHHHHEEE
ANMTDDYYRFEERQMALIGERQAKVFRIGDTVKVKVTHVDVDERLIDFQIVGMPLPKNDR
ECCCHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEEEEECCCHHEEEEEEEECCCCCCCC
SQRPARGKTIQAKTRGKSLDKSKSDDKGRKKKGKQRKGKNQRNNDKSGNSKHKPFYKDKS
CCCCCCCCEEEEHHCCCCCCCCCCCCHHHHHHCHHHCCCCCCCCCCCCCCCCCCCCCCHH
VKKKARRKKK
HHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]