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The map label for this gene is setA [H]

Identifier: 148267133

GI number: 148267133

Start: 766384

End: 767598

Strand: Direct

Name: setA [H]

Synonym: SaurJH9_0697

Alternate gene names: 148267133

Gene position: 766384-767598 (Clockwise)

Preceding gene: 148267132

Following gene: 148267134

Centisome position: 26.37

GC content: 32.26

Gene sequence:

>1215_bases
ATGTTTGCAGCGTTATTACAAATAAAGAATTATAAACTCTTTGTTGCTAATATGTTTCTACTAGGTATGGGTATTGCGGT
TACGGTCCCATATCTTGTTCTTTTTGCAACTAAAGATTTAGGTATGACAACAAATCAGTATGGATTACTTCTAGCATCTG
CAGCGATTAGCCAGTTTACAGTAAATTCAATTATTGCTAGATTTTCGGATACGCATCACTTTAATAGAAAAATTATTATT
ATTCTCGCATTATTAATGGGTGCGCTTGGTTTTTCAATATACTTTTTTGTAGATACAATCTGGTTATTCATATTACTATA
TGCGATTTTCCAAGGATTATTTGCACCAGCAATGCCCCAACTTTACGCATCTGCTAGAGAATCTATCAATGTTTCAAGCT
CTAAAGATAGAGCTCAATTTGCCAACACAGTATTACGTTCAATGTTCTCATTGGGCTTTTTATTTGGTCCATTTATTGGT
GCCCAATTAATCGGTTTAAAAGGCTATGCTGGATTGTTTGGTGGAACAATAAGTATCATTTTATTTACTTTAGTACTTCA
AGTGTTTTTCTATAAGGATTTAAACATTAAACACCCTATTAGTACGCAACAACATGTTGAAAAAATTGCTCCTAATATGT
TTAAAGACAAAACGCTTTTATTACCATTTATTGCATTTATTTTATTACACATTGGACAATGGATGTATACGATGAATATG
CCTTTATTTGTTACTGATTATTTAAAAGAAAATGAGCAACATGTCGGTTATTTAGCTAGTTTATGTGCTGGTTTAGAAGT
GCCATTTATGATCATTCTTGGCGTTTTATCATCTAGATTACATACTCGAACATTGTTGATTTATGGAGCGATTTTTGGTG
GTTTATTCTACTTCAGCATTGGGGTATTTAAAAACTTCTATATGATGTTAGCAGGACAGGTATTTTTAGCTATTTTCTTA
GCGGTTCTTTTAGGAATTGGTATTAGTTATTTCCAAGATATCTTACCAGATTTTCCAGGATACGCCTCAACACTATTTTC
TAATGCAATGGTTATTGGACAGTTAGGCGGTAACCTATTAGGTGGTGCTATGAGTCACTGGGTAGGTTTGGAAAATGTAT
TTTTTGTATCAGCAGCATCAATCATGTTAGGTATGATACTTATATTCTTTACTAAAAATCAAAAAATTACAAAAGAGGAT
ATGATATCAACATGA

Upstream 100 bases:

>100_bases
TATTCGGTTAAATTGAACGTAGTTGTTTGCTAACGCACCAACAGCAAAAGAGCCCCTAATTAATAAATTAAAAGGGGCTC
TAAGAAGCGGGGTTATGGAT

Downstream 100 bases:

>100_bases
CAATTATTTTATGGCTACTTATCATCGCTGCCTTCATGTTAGCATTTGTTGGGTTGATTAAGCCGATTATTCCTTCTGTT
TTAGTATTATGGGTTGGCTT

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 404

Protein sequence:

>404_residues
MFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIII
ILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIG
AQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNM
PLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFL
AVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKED
MIST

Sequences:

>Translated_404_residues
MFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIII
ILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIG
AQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNM
PLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFL
AVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKED
MIST
>Mature_404_residues
MFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFTVNSIIARFSDTHHFNRKIII
ILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQLYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIG
AQLIGLKGYAGLFGGTISIILFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNM
PLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSIGVFKNFYMMLAGQVFLAIFL
AVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLLGGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKED
MIST

Specific function: Involved in the efflux of sugars. The physiological role may be the detoxification of non-metabolizable sugar analogs. Can transport IPTG, lactose and glucose. Has broad substrate specificity, with preferences for glucosides or galactosides with alkyl or

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Set transporter family [H]

Homologues:

Organism=Escherichia coli, GI48994875, Length=393, Percent_Identity=28.2442748091603, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1790091, Length=376, Percent_Identity=27.1276595744681, Blast_Score=141, Evalue=9e-35,
Organism=Escherichia coli, GI1788495, Length=351, Percent_Identity=27.6353276353276, Blast_Score=105, Evalue=5e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004750 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 44926; Mature: 44926

Theoretical pI: Translated: 9.53; Mature: 9.53

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFT
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQ
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISII
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNM
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
PLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSI
CHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHCCHHHHHHCCHHH
GGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDMIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC
>Mature Secondary Structure
MFAALLQIKNYKLFVANMFLLGMGIAVTVPYLVLFATKDLGMTTNQYGLLLASAAISQFT
CCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
VNSIIARFSDTHHFNRKIIIILALLMGALGFSIYFFVDTIWLFILLYAIFQGLFAPAMPQ
HHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LYASARESINVSSSKDRAQFANTVLRSMFSLGFLFGPFIGAQLIGLKGYAGLFGGTISII
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LFTLVLQVFFYKDLNIKHPISTQQHVEKIAPNMFKDKTLLLPFIAFILLHIGQWMYTMNM
HHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
PLFVTDYLKENEQHVGYLASLCAGLEVPFMIILGVLSSRLHTRTLLIYGAIFGGLFYFSI
CHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GVFKNFYMMLAGQVFLAIFLAVLLGIGISYFQDILPDFPGYASTLFSNAMVIGQLGGNLL
HHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHCCHHHHHHCCHHH
GGAMSHWVGLENVFFVSAASIMLGMILIFFTKNQKITKEDMIST
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1630901; 9278503; 10209755; 10438463 [H]