Click here to switch to the map view.

The map label for this gene is dhaK [H]

Identifier: 148267109

GI number: 148267109

Start: 740966

End: 741934

Strand: Direct

Name: dhaK [H]

Synonym: SaurJH9_0673

Alternate gene names: 148267109

Gene position: 740966-741934 (Clockwise)

Preceding gene: 148267108

Following gene: 148267110

Centisome position: 25.49

GC content: 35.71

Gene sequence:

>969_bases
ATGATGAAAAAGTTAATCAATAAAAAAGAAACATTTTTAACTGATATGCTTGAAGGATTGTTAATTGCGCACCCAGAGTT
AGATCTGATTGCTAATACAGTTATTGTAAAAAAAGCTAAGAAAGAACATGGTGTAGCAATAGTCTCTGGAGGTGGAAGCG
GACATGAACCTGCGCATGCCGGTTTTGTTGCAGAAGGTATGCTAGATGCAGCGGTTTGTGGCGAAGTATTTACATCACCT
ACACCTGATAAAATATTAGAAGCTATTAAAGCAGTAGATACTGGTGATGGTGTATTACTAGTTGTAAAAAACTATGCAGG
TGACGTGATGAATTTCGAAATGGCACAAGAGCTTGCAGAAATGGAAGGTATAAATGTTCAAACTGTTATTGTTCGTGACG
ACATTGCTGTGACAAACGAAGTACAACGTCGTGGTGTTGCAGGAACAGTGTTTGTTCATAAGCTTGCCGGTTATCTTGCT
GAAAAAGGTTATTCATTAACAGAGATAAAATCGCGTGTAGAAGCGTTGTTACCTGAAATTAAAAGTATTGGTATGGCAAT
TGAGCCACCGCTTGTTCCAACTACTGGAAAATATGGCTTTGATATTGAAGACGACAAAATGGAAATCGGTATTGGTATAC
ATGGTGAAAAAGGTATTCATAGGGAAGAAGTAAAGGATATTGATCATATTGTTGGAACATTGTTAGACGAATTGTATAAA
GAAGTTACTGCCAATGATGTCATATTAATGGTAAATGGTATGGGTGGTACGCCGTTATCTGAATTAAATATCGTAACTAA
ATATATTCAACAAAATTTAGCTGCAAGAACGGTTAATGTTGCTAAATGGTTTGTTGGTGATTATATGACATCTTTAGACA
TGCAAGGTTTTTCTATAACTATCGTGCCTAATAAACCAGAATATTTGGAAGCATTTTTAGCACCAACAACAAGTCAATAC
TTTAAATAA

Upstream 100 bases:

>100_bases
TCAAAAATATATTTGATAACGGTATCAGGTTAATTCTTTATGATAGCGCATTCATTTATTCTGTTTTATACTATGACTGA
TAATACCAAGGAGGTACAAC

Downstream 100 bases:

>100_bases
GAAGTGAATATGAATAAATATACATTTATGAGGTGGCACAAATGAAAGTGAATGATATGAAAGCACGTTTATTAAATTTA
GAAGAAACGTTTAAAAAACA

Product: dihydroxyacetone kinase subunit DhaK

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSP
TPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLA
EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQY
FK

Sequences:

>Translated_322_residues
MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSP
TPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLA
EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQY
FK
>Mature_322_residues
MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHAGFVAEGMLDAAVCGEVFTSP
TPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAEMEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLA
EKGYSLTEIKSRVEALLPEIKSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSITIVPNKPEYLEAFLAPTTSQY
FK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=334, Percent_Identity=38.622754491018, Blast_Score=225, Evalue=4e-59,
Organism=Escherichia coli, GI87081857, Length=346, Percent_Identity=41.3294797687861, Blast_Score=246, Evalue=2e-66,
Organism=Caenorhabditis elegans, GI17565018, Length=327, Percent_Identity=33.0275229357798, Blast_Score=184, Evalue=4e-47,
Organism=Saccharomyces cerevisiae, GI6321055, Length=343, Percent_Identity=34.9854227405248, Blast_Score=172, Evalue=6e-44,
Organism=Saccharomyces cerevisiae, GI6323570, Length=320, Percent_Identity=35, Blast_Score=170, Evalue=4e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 35019; Mature: 35019

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHA
CCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GFVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
MEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAEKGYSLTEIKSRVEALLPEI
HCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
HHCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSIT
HHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVPNKPEYLEAFLAPTTSQYFK
EECCCHHHHHHHHCCCHHHHCC
>Mature Secondary Structure
MMKKLINKKETFLTDMLEGLLIAHPELDLIANTVIVKKAKKEHGVAIVSGGGSGHEPAHA
CCHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCC
GFVAEGMLDAAVCGEVFTSPTPDKILEAIKAVDTGDGVLLVVKNYAGDVMNFEMAQELAE
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHHH
MEGINVQTVIVRDDIAVTNEVQRRGVAGTVFVHKLAGYLAEKGYSLTEIKSRVEALLPEI
HCCCCEEEEEEECCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
KSIGMAIEPPLVPTTGKYGFDIEDDKMEIGIGIHGEKGIHREEVKDIDHIVGTLLDELYK
HHCCCEECCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EVTANDVILMVNGMGGTPLSELNIVTKYIQQNLAARTVNVAKWFVGDYMTSLDMQGFSIT
HHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
IVPNKPEYLEAFLAPTTSQYFK
EECCCHHHHHHHHCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]