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The map label for this gene is ykgC [H]

Identifier: 148267054

GI number: 148267054

Start: 684770

End: 686092

Strand: Reverse

Name: ykgC [H]

Synonym: SaurJH9_0617

Alternate gene names: 148267054

Gene position: 686092-684770 (Counterclockwise)

Preceding gene: 148267055

Following gene: 148267047

Centisome position: 23.6

GC content: 34.62

Gene sequence:

>1323_bases
ATGAAAACATATGATTTAATTGTAATAGGATTTGGGAAAGCTGGTAAAACTTTAGCGAAATATGCTGCATCAACAGGTCA
ACACGTCGCAGTTATCGAACAATCTTCGAAAATGTATGGCGGCACTTGTATAAATATAGGATGTATACCTTCGAAGACAC
TTGTACATGATGGATTAGAAGGCAAATCTTTTGAAGCAAGTTATAACCGTAAAAACGATGTTGTCAATGCGCTAAACAAT
AAAAATTACCACTTATTAGCAGACGATAACAACATTGATGTATTGGATTTTAAAGCGCAGTTTAAATCTAATACTGAAGT
GAATTTATTAGATCAGCATGGCGATATCGTCGATAGTATTACTGCACCTCATATCATTATTAATACCGGTGCTACCTCTA
TCATTCCTAACATAAAAGGCCTTGATCAAGCTAAACATGTCTTCGATTCAACAGGTTTATTAAACATTAGCTATCAACCT
AAGCATCTCGTTATTGTAGGTGGCGGTTATATTGCCTTAGAATTTGCTTCAATGTTTGCGAATTTAGGTAGTAAGGTAAC
AGTATTAGAACGTGGTGAATCATTTATGCCACGCGAAGATCAAGATGTCGTTGCACATGCTATTACTGACTTAGAAAATA
AAGGCATTGCATTGCATACAAATGTTGAAACGACTGAATTGTCATCTGACGATCATCATACAACAGTCCGTACTAATGTT
GGCAACTTTGAGGCTGATGCAGTACTTTTGGCTATCGGGCGCAAACCGAATACAGCCTTAGCTTTAGAAAATACTGATAT
CGAATTAGGTGATAGAGGCGAAATTAAAGTCAATGCTCAACTTCAAACATCTGTGCCACATATTTATGCTGCAGGTGATG
TTAAAGGCGGACTTCAATTTACGTATATATCTTTAGATGATTATCGAATTATCAAATCAGCGTTATATGGTAATCAGTCA
CGTACGACTGACAATAGAGGTAGCGTGCCTTATACAGTATTTATAGATCCACCATTATCACGTGTTGGATTAACTAGTAA
AGAAGCTGCCGCTCAACATTATGATTACACTGAACATCAACTTTTAGTAAGTGCTATACCTCGTCACAAAATTAACAATG
ATCCAAGAGGTTTATTTAAAGTAGTCATTAATAATGAAAATAATATGATTTTAGGTGCTACATTATATGGTAAGCAATCT
GAAGAATTAATTAATATAATTAAACTTGCGATTGATCAAAACATTCCATATACCGTATTACGAGATAATATTTATACACA
TCCTACGATGGCCGAATCATTTAATGATTTATTTAATTTCTAG

Upstream 100 bases:

>100_bases
TCACATTATCAGCAAGACGAACAGAATATCATTATTAATTTTTATAATGAAAAAACAATCAAAGATGTCATTGAAGACAT
TCAAAAGGAGGATTTATGTC

Downstream 100 bases:

>100_bases
ACAAAACATAAAAACCTGGTGGCACGCATTGAATGATGCTGCCATCAGGTTTTATTGTTGTGCTTTTCGCTTTTCTAATT
TTTCTTTAAGCTTTCTATCT

Product: FAD-dependent pyridine nucleotide-disulphide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNN
KNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSITAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQP
KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNV
GNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQS
RTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQS
EELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF

Sequences:

>Translated_440_residues
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNN
KNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSITAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQP
KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNV
GNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQS
RTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQS
EELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF
>Mature_440_residues
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLEGKSFEASYNRKNDVVNALNN
KNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSITAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQP
KHLVIVGGGYIALEFASMFANLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNV
GNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQFTYISLDDYRIIKSALYGNQS
RTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQLLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQS
EELINIIKLAIDQNIPYTVLRDNIYTHPTMAESFNDLFNF

Specific function: Unknown

COG id: COG1249

COG function: function code C; Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family [H]

Homologues:

Organism=Homo sapiens, GI91199540, Length=462, Percent_Identity=27.4891774891775, Blast_Score=157, Evalue=1e-38,
Organism=Homo sapiens, GI50301238, Length=466, Percent_Identity=27.2532188841202, Blast_Score=147, Evalue=3e-35,
Organism=Homo sapiens, GI22035672, Length=481, Percent_Identity=27.2349272349272, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI291045266, Length=463, Percent_Identity=25.0539956803456, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI148277065, Length=464, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI33519430, Length=464, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI33519428, Length=464, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI33519426, Length=464, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI148277071, Length=464, Percent_Identity=25, Blast_Score=107, Evalue=2e-23,
Organism=Homo sapiens, GI291045268, Length=459, Percent_Identity=23.3115468409586, Blast_Score=95, Evalue=1e-19,
Organism=Escherichia coli, GI87081717, Length=441, Percent_Identity=49.2063492063492, Blast_Score=418, Evalue=1e-118,
Organism=Escherichia coli, GI1786307, Length=451, Percent_Identity=28.159645232816, Blast_Score=167, Evalue=9e-43,
Organism=Escherichia coli, GI87082354, Length=456, Percent_Identity=28.2894736842105, Blast_Score=166, Evalue=2e-42,
Organism=Escherichia coli, GI1789915, Length=439, Percent_Identity=27.3348519362187, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1787114, Length=190, Percent_Identity=28.9473684210526, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI32565766, Length=461, Percent_Identity=28.8503253796095, Blast_Score=164, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17557007, Length=475, Percent_Identity=28.4210526315789, Blast_Score=142, Evalue=4e-34,
Organism=Caenorhabditis elegans, GI71983419, Length=465, Percent_Identity=27.5268817204301, Blast_Score=129, Evalue=2e-30,
Organism=Caenorhabditis elegans, GI71983429, Length=465, Percent_Identity=27.5268817204301, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI71982272, Length=489, Percent_Identity=24.5398773006135, Blast_Score=108, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6321091, Length=469, Percent_Identity=27.5053304904051, Blast_Score=152, Evalue=1e-37,
Organism=Saccharomyces cerevisiae, GI6325166, Length=473, Percent_Identity=27.4841437632135, Blast_Score=148, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6325240, Length=470, Percent_Identity=27.0212765957447, Blast_Score=123, Evalue=7e-29,
Organism=Drosophila melanogaster, GI21358499, Length=464, Percent_Identity=29.5258620689655, Blast_Score=165, Evalue=5e-41,
Organism=Drosophila melanogaster, GI24640549, Length=478, Percent_Identity=28.4518828451883, Blast_Score=123, Evalue=2e-28,
Organism=Drosophila melanogaster, GI24640553, Length=478, Percent_Identity=28.4518828451883, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24640551, Length=478, Percent_Identity=28.4518828451883, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17737741, Length=481, Percent_Identity=26.4033264033264, Blast_Score=113, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016156
- InterPro:   IPR013027
- InterPro:   IPR004099
- InterPro:   IPR012999
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2; PF02852 Pyr_redox_dim [H]

EC number: NA

Molecular weight: Translated: 48303; Mature: 48303

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS00076 PYRIDINE_REDOX_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLE
CCEEEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHCCCC
GKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSI
CCCEECCCCCCHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCEEEEECCCCCCHHHC
TAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFA
CCCEEEEECCCHHCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEHHHHHHHH
NLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNV
HCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEECC
GNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQF
CCCCCCEEEEEECCCCCEEEEEECCCEEECCCCCEEEEEEEECCCCEEEEECCCCCCEEE
TYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQ
EEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHH
LLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVL
HHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
RDNIYTHPTMAESFNDLFNF
ECCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKTYDLIVIGFGKAGKTLAKYAASTGQHVAVIEQSSKMYGGTCINIGCIPSKTLVHDGLE
CCEEEEEEEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCEEEEEECCCCHHHHHCCCC
GKSFEASYNRKNDVVNALNNKNYHLLADDNNIDVLDFKAQFKSNTEVNLLDQHGDIVDSI
CCCEECCCCCCHHHHHHHCCCCEEEEECCCCEEEEEEEECCCCCCEEEEECCCCCCHHHC
TAPHIIINTGATSIIPNIKGLDQAKHVFDSTGLLNISYQPKHLVIVGGGYIALEFASMFA
CCCEEEEECCCHHCCCCCCCCHHHHHHHCCCCEEEEEECCCEEEEECCCEEEHHHHHHHH
NLGSKVTVLERGESFMPREDQDVVAHAITDLENKGIALHTNVETTELSSDDHHTTVRTNV
HCCCEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCEEEEECCCEEECCCCCCCEEEEECC
GNFEADAVLLAIGRKPNTALALENTDIELGDRGEIKVNAQLQTSVPHIYAAGDVKGGLQF
CCCCCCEEEEEECCCCCEEEEEECCCEEECCCCCEEEEEEEECCCCEEEEECCCCCCEEE
TYISLDDYRIIKSALYGNQSRTTDNRGSVPYTVFIDPPLSRVGLTSKEAAAQHYDYTEHQ
EEEECCCHHHHHHHHCCCCCCCCCCCCCCCEEEEECCCHHHHCCCCHHHHHHHCCCHHHH
LLVSAIPRHKINNDPRGLFKVVINNENNMILGATLYGKQSEELINIIKLAIDQNIPYTVL
HHHHHCCCCCCCCCCCEEEEEEEECCCCEEEEEEECCCCHHHHHHHHHHHHCCCCCEEEE
RDNIYTHPTMAESFNDLFNF
ECCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: FAD. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]