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The map label for this gene is ung

Identifier: 148267041

GI number: 148267041

Start: 672809

End: 673465

Strand: Direct

Name: ung

Synonym: SaurJH9_0604

Alternate gene names: 148267041

Gene position: 672809-673465 (Clockwise)

Preceding gene: 148267038

Following gene: 148267042

Centisome position: 23.15

GC content: 35.46

Gene sequence:

>657_bases
ATGGAATGGTCGCAAATTTTTCATGACATAACAACGAAACATGACTTTAAAGCTATGCATGATTTTTTAGAAAAAGAATA
TTCGACTGCAATCGTATACCCTGATAGGGAAAATATATATCAAGCGTTTGATTTAACACCGTTTGAAAATATCAAAGTTG
TTATATTAGGACAAGACCCGTATCATGGTCCAAACCAAGCACATGGATTAGCATTTTCAGTGCAACCTAACGCAAAATTC
CCTCCATCTTTACGTAATATGTATAAAGAATTAGCAGATGATATTGGATGCGTTAGACAAACACCGCATTTACAAGATTG
GGCAAGAGAAGGCGTCTTGTTATTGAATACAGTTTTAACCGTAAGACAGGGTGAAGCAAATTCTCATCGTGATATTGGTT
GGGAAACATTTACTGATGAAATTATTAAAGCAGTGTCTGATTATAAAGAACATGTTGTCTTTATTTTGTGGGGGAAACCT
GCACAGCAAAAAATAAAGCTTATCGATACATCTAAACATTGTATTATAAAATCAGTGCATCCTAGTCCACTGTCTGCATA
TAGAGGATTCTTTGGATCAAAACCGTATTCCAAAGCGAATGCCTATTTAGAGTCAGTAGGAAAATCACCAATTAATTGGT
GTGAAAGTGAGGCGTAG

Upstream 100 bases:

>100_bases
TGATTGTTGAAATGAATCATTCATACTATTGTAACTTTTGAAAATGTCATTCACTTTAGATAAGTGTGATATGTTAAAAT
ATGTCCTGAGGTGAGATTGA

Downstream 100 bases:

>100_bases
ATGGTGAATAGAGAAACTTTAATAGCACGAATTGAGCAAGAATTAGTACAAGCAGAGCAGGCACAGCATGACCATGACTT
TGAAAAACATATGTATGCCA

Product: uracil-DNA glycosylase

Products: NA

Alternate protein names: UDG

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKF
PPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA

Sequences:

>Translated_218_residues
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKF
PPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
>Mature_218_residues
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDPYHGPNQAHGLAFSVQPNAKF
PPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLTVRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKP
AQQKIKLIDTSKHCIIKSVHPSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA

Specific function: Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine

COG id: COG0692

COG function: function code L; Uracil DNA glycosylase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the uracil-DNA glycosylase family

Homologues:

Organism=Homo sapiens, GI19718751, Length=202, Percent_Identity=48.5148514851485, Blast_Score=198, Evalue=2e-51,
Organism=Homo sapiens, GI6224979, Length=202, Percent_Identity=48.5148514851485, Blast_Score=198, Evalue=3e-51,
Organism=Escherichia coli, GI1788934, Length=189, Percent_Identity=54.4973544973545, Blast_Score=222, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI17556304, Length=217, Percent_Identity=49.3087557603687, Blast_Score=207, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6323620, Length=220, Percent_Identity=45, Blast_Score=169, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): UNG_STAA1 (A7WZ22)

Other databases:

- EMBL:   AP009324
- RefSeq:   YP_001441169.1
- ProteinModelPortal:   A7WZ22
- SMR:   A7WZ22
- STRING:   A7WZ22
- EnsemblBacteria:   EBSTAT00000002840
- GeneID:   5559645
- GenomeReviews:   AP009324_GR
- KEGG:   saw:SAHV_0579
- eggNOG:   COG0692
- GeneTree:   EBGT00050000024952
- HOGENOM:   HBG605450
- OMA:   ARAFRQQ
- ProtClustDB:   PRK05254
- BioCyc:   SAUR418127:SAHV_0579-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00148
- InterPro:   IPR002043
- InterPro:   IPR018085
- InterPro:   IPR005122
- Gene3D:   G3DSA:3.40.470.10
- PANTHER:   PTHR11264
- TIGRFAMs:   TIGR00628

Pfam domain/function: PF03167 UDG; SSF52141 UDNA_glycsylseSF

EC number: =3.2.2.27

Molecular weight: Translated: 24937; Mature: 24937

Theoretical pI: Translated: 6.68; Mature: 6.68

Prosite motif: PS00130 U_DNA_GLYCOSYLASE

Important sites: ACT_SITE 59-59

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDP
CCHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
YHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLT
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHH
VRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVH
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHEEEEECCCCEEEEECC
PSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
CCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCCCC
>Mature Secondary Structure
MEWSQIFHDITTKHDFKAMHDFLEKEYSTAIVYPDRENIYQAFDLTPFENIKVVILGQDP
CCHHHHHHHHHCCHHHHHHHHHHHHHHCEEEEECCHHHHHHHHCCCCCCCEEEEEECCCC
YHGPNQAHGLAFSVQPNAKFPPSLRNMYKELADDIGCVRQTPHLQDWAREGVLLLNTVLT
CCCCCCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHCCCHHHHHHHH
VRQGEANSHRDIGWETFTDEIIKAVSDYKEHVVFILWGKPAQQKIKLIDTSKHCIIKSVH
HCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCEEEEEECCCCHHHEEEEECCCCEEEEECC
PSPLSAYRGFFGSKPYSKANAYLESVGKSPINWCESEA
CCHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA