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The map label for this gene is treR [H]

Identifier: 148266934

GI number: 148266934

Start: 535890

End: 536618

Strand: Direct

Name: treR [H]

Synonym: SaurJH9_0497

Alternate gene names: 148266934

Gene position: 535890-536618 (Clockwise)

Preceding gene: 148266933

Following gene: 148266935

Centisome position: 18.44

GC content: 33.74

Gene sequence:

>729_bases
ATGGCGAAACAAAAAAAGTTTATGAAGATTTATGAGGCGTTGAAAGAAGATATATTAAACGGGCAGATTCAATATGGTGA
ACAAATTCCGTCTGAACATGATTTGGTGCAATTGTACCAGTCATCTCGAGAGACCGTGCGTAAGGCATTAGATTTGTTGG
CATTAGACGGCATGATTCAAAAGATTCATGGTAAAGGGTCACTTGTCATTTATCAGGAGGTTACAGAGTTTCCATTTTCT
GAACTTGTTAGTTTTAAAGAAATGCAAGAAGAAATGGGCGTCGCATATTTAACTGAAGTTGTTGTGAATGAGGTTGTTGA
AGCGCATGAAGTTCCAGAAGTTCAACATGCTTTAAACATCAATTCTAGTGAATCGCTCATTCATATTGTTAGAACTCGTC
GGCTTAACCAACATGTGAAGATTGTTGATGAAGATTATTTTCTAAAGTCGATTGTTTCAGATATAGGTAATGATGTTGCG
AGTGATTCTATTTATGATTATTTGGAAAAGGTATTAAATCTTAATATTAGTTATTCAAGTAAGTCTATTACTTTTGAACC
GTTTGATGAACAAGCATATCAATTGTTTGGTGATGTATCGGTGGCTTATTCAGCAACAGTTCGAAGTATTGTGTATTTAG
AAAATACAATGCCGTTTCAATATAATATTTCAAAACATCTTGCAAATGAATTTAAATTTAACGACTTCTCAAGACGTCGT
ATAAAGTAA

Upstream 100 bases:

>100_bases
TGTGATTCAAACAGGCACAGTGGAAAATAATACGATAAGCGGGTTTGGTGCAATTGTAATCGAAACAAACGCGTAAAATA
AATTGAGTGGATGCGTTTAT

Downstream 100 bases:

>100_bases
ACAATGATATAAATGATTTATACTTGCAATTAACTATTAAAATATAGTAATATATATCTTGCCGTGCTAGGTGGGGAGGT
AGCGGTTCCCTGTACTCGAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MAKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFS
ELVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVA
SDSIYDYLEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRR
IK

Sequences:

>Translated_242_residues
MAKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFS
ELVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVA
SDSIYDYLEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRR
IK
>Mature_241_residues
AKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQKIHGKGSLVIYQEVTEFPFSE
LVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNINSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVAS
DSIYDYLEKVLNLNISYSSKSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRRI
K

Specific function: Repressor for the trehalose operon (treP and treA). Binds trehalose-6-phosphate, which probably acts as an inducer [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=244, Percent_Identity=24.5901639344262, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI87082252, Length=140, Percent_Identity=30.7142857142857, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR012770
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27963; Mature: 27832

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQ
CCCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIHGKGSLVIYQEVTEFPFSELVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNI
HHCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
NSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDYLEKVLNLNISYSS
CCHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECC
KSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRR
CCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCCHHCC
IK
CC
>Mature Secondary Structure 
AKQKKFMKIYEALKEDILNGQIQYGEQIPSEHDLVQLYQSSRETVRKALDLLALDGMIQ
CCHHHHHHHHHHHHHHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KIHGKGSLVIYQEVTEFPFSELVSFKEMQEEMGVAYLTEVVVNEVVEAHEVPEVQHALNI
HHCCCCCEEEEHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCC
NSSESLIHIVRTRRLNQHVKIVDEDYFLKSIVSDIGNDVASDSIYDYLEKVLNLNISYSS
CCHHHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEECC
KSITFEPFDEQAYQLFGDVSVAYSATVRSIVYLENTMPFQYNISKHLANEFKFNDFSRRR
CCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECHHHHHHHHCCCCCCHHCC
IK
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8917076; 8969503; 9384377; 7651129; 8755887 [H]