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The map label for this gene is galE [C]

Identifier: 148266554

GI number: 148266554

Start: 135987

End: 136958

Strand: Direct

Name: galE [C]

Synonym: SaurJH9_0114

Alternate gene names: 148266554

Gene position: 135987-136958 (Clockwise)

Preceding gene: 148266553

Following gene: 148266555

Centisome position: 4.68

GC content: 31.89

Gene sequence:

>972_bases
TTGGAAAGAGTTTTGATAACTGGTGGGGCTGGTTTTATTGGGTCGCATTTAGTAGATGATTTACAACAAGATTATGATGT
TTATGTTCTAGATAACTATAGAACAGGTAAACGAGAAAATATTAAAAGTTTGGCTGACGATCATGTGTTTGAATTAGATA
TTCGTGAATATGATGCAGTTGAACAAATCATGAAGACATATCAATTTGATTATGTTATTCATTTAGCAGCATTAGTTAGT
GTTGCTGAGTCGGTTGAGAAACCTATCTTATCTCAAGAAATAAACGTCGTAGCAACATTAAGATTGTTAGAAATCATTAA
AAAATATAATAGTCATATAAAACGTTTTATCTTTGCTTCGTCAGCAGCTGTTTATGGTGATCTTCCTGATTTGCCTAAAA
GTGATCAATCATTAATCTTACCATTATCACCATATGCAATAGATAAATATTACGGCGAACGGACGACATTAAATTATTGC
TCGTTATATAACATACCAACAGCGGTTGTTAAATTTTTTAATGTATTTGGGCCAAGACAGGATCCTAAGTCACAATATTC
AGGTGTTATTTCAAAGATGTTCGATTCATTTGAGCATAACAAGCCATTTACATTTTTTGGTGACGGACTGCAAACTAGAG
ATTTTGTATATGTATATGATGTTGTTCAATCTGTACGCTTAATTATGGAACACAAAGATGCAATTGGACACGGTTATAAC
ATTGGTACAGGCACTTTTACTAATTTATTAGAGGTTTATCGTATTATTGGTGAATTATATGGAAAATCAGTCGAGCATGA
ATTTAAAGAAGCACGAAAAGGAGATATTAAGCATTCTTATGCAGATATTTCTAACTTAAAGGCATTAGGATTTGTTCCTA
AATATACAGTAGAAACAGGTTTAAAGGATTACTTTAATTTTGAGGTAGATAATATTGAAGAAGTTACAGCTAAAGAAGTG
GAAATGTCGTGA

Upstream 100 bases:

>100_bases
TTATCTCATTTTATTTTTATAAATAAAAAATATCGATAAAAAGCTTACAATACTTTATGTTTTTATGATATATTTTTAAT
GTATAAATGAGGTGGAAGAT

Downstream 100 bases:

>100_bases
AAATGACATTGAAGCTGTCCATAATAATAAGGGTTATGCCTATCAAAGAAAATTAGATGCACTCGAAGAAGTGAGAAAAG
GCTATTACCCAATTAAACGT

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENIKSLADDHVFELDIREYDAVEQIMKTYQFDYVIHLAALVS
VAESVEKPILSQEINVVATLRLLEIIKKYNSHIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTLNYC
SLYNIPTAVVKFFNVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEHKDAIGHGYN
IGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDIKHSYADISNLKALGFVPKYTVETGLKDYFNFEVDNIEEVTAKEV
EMS

Sequences:

>Translated_323_residues
MERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENIKSLADDHVFELDIREYDAVEQIMKTYQFDYVIHLAALVS
VAESVEKPILSQEINVVATLRLLEIIKKYNSHIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTLNYC
SLYNIPTAVVKFFNVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEHKDAIGHGYN
IGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDIKHSYADISNLKALGFVPKYTVETGLKDYFNFEVDNIEEVTAKEV
EMS
>Mature_323_residues
MERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENIKSLADDHVFELDIREYDAVEQIMKTYQFDYVIHLAALVS
VAESVEKPILSQEINVVATLRLLEIIKKYNSHIKRFIFASSAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTLNYC
SLYNIPTAVVKFFNVFGPRQDPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEHKDAIGHGYN
IGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDIKHSYADISNLKALGFVPKYTVETGLKDYFNFEVDNIEEVTAKEV
EMS

Specific function: Galactose metabolism; third step. [C]

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI42516563, Length=321, Percent_Identity=31.7757009345794, Blast_Score=135, Evalue=4e-32,
Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=28.5294117647059, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=28.5294117647059, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=28.5294117647059, Blast_Score=128, Evalue=8e-30,
Organism=Homo sapiens, GI7657641, Length=325, Percent_Identity=28, Blast_Score=121, Evalue=9e-28,
Organism=Escherichia coli, GI1786974, Length=331, Percent_Identity=31.7220543806647, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1788353, Length=345, Percent_Identity=30.1449275362319, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=27.7936962750716, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1788366, Length=240, Percent_Identity=25.4166666666667, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI1790049, Length=317, Percent_Identity=27.4447949526814, Blast_Score=74, Evalue=9e-15,
Organism=Escherichia coli, GI1788365, Length=332, Percent_Identity=22.5903614457831, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788589, Length=341, Percent_Identity=25.8064516129032, Blast_Score=65, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17539532, Length=320, Percent_Identity=30, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI71982035, Length=349, Percent_Identity=28.3667621776504, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71982038, Length=351, Percent_Identity=28.2051282051282, Blast_Score=121, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI17568069, Length=275, Percent_Identity=33.8181818181818, Blast_Score=108, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI115532424, Length=271, Percent_Identity=27.6752767527675, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17539422, Length=282, Percent_Identity=27.3049645390071, Blast_Score=78, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI17539424, Length=282, Percent_Identity=27.3049645390071, Blast_Score=77, Evalue=8e-15,
Organism=Caenorhabditis elegans, GI133901790, Length=282, Percent_Identity=27.3049645390071, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI133901786, Length=282, Percent_Identity=27.3049645390071, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI133901788, Length=282, Percent_Identity=27.3049645390071, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507723, Length=272, Percent_Identity=25.7352941176471, Blast_Score=68, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=28.5714285714286, Blast_Score=124, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21356223, Length=331, Percent_Identity=29.9093655589124, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI19923002, Length=340, Percent_Identity=26.4705882352941, Blast_Score=111, Evalue=7e-25,
Organism=Drosophila melanogaster, GI24158427, Length=253, Percent_Identity=24.5059288537549, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 36900; Mature: 36900

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENIKSLADDHVFELDIREYDAV
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCEEEECHHHHHHH
EQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVATLRLLEIIKKYNSHIKRFIFAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTLNYCSLYNIPTAVVKFFNVFGPRQ
CCHHCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCEEHHHHHHCCHHHHHHHHHHHCCCC
DPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEHKDAIGHGYN
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
IGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDIKHSYADISNLKALGFVPKYTVETG
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
LKDYFNFEVDNIEEVTAKEVEMS
HHHHHCCCCCCHHHHHHHHHCCC
>Mature Secondary Structure
MERVLITGGAGFIGSHLVDDLQQDYDVYVLDNYRTGKRENIKSLADDHVFELDIREYDAV
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHCCCEEEECHHHHHHH
EQIMKTYQFDYVIHLAALVSVAESVEKPILSQEINVVATLRLLEIIKKYNSHIKRFIFAS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
SAAVYGDLPDLPKSDQSLILPLSPYAIDKYYGERTTLNYCSLYNIPTAVVKFFNVFGPRQ
CCHHCCCCCCCCCCCCCEEEECCCHHHHHHCCCCCEEHHHHHHCCHHHHHHHHHHHCCCC
DPKSQYSGVISKMFDSFEHNKPFTFFGDGLQTRDFVYVYDVVQSVRLIMEHKDAIGHGYN
CHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
IGTGTFTNLLEVYRIIGELYGKSVEHEFKEARKGDIKHSYADISNLKALGFVPKYTVETG
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCHHHHHH
LKDYFNFEVDNIEEVTAKEVEMS
HHHHHCCCCCCHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]