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The map label for this gene is copA [H]

Identifier: 148241682

GI number: 148241682

Start: 516988

End: 518586

Strand: Direct

Name: copA [H]

Synonym: SynRCC307_0583

Alternate gene names: 148241682

Gene position: 516988-518586 (Clockwise)

Preceding gene: 148241680

Following gene: 148241683

Centisome position: 23.24

GC content: 62.04

Gene sequence:

>1599_bases
TTGCTTCGTCGCTCCTTTCTGCAACTCGGTGTGCTCGGCGCAGTGATCGGCGGCGCCAGCCTGGAGCTGTTTCAGCAAGC
CAAAGCATCAGCTCGCCGTTCCTGGGAGCGGTTCATTGCTCAGCCGGCGTTTCAGCGGCCCCGCAATGCCGCCACGGTGG
TGCTTGAGGTCGCCACGGCACCGATCACGGTGTTGGGGCAGACCGTTGTTCGGGGCTGCATCCGTCAGCTCAATGGCCAG
CGGGGCTACACCACGTCCCAAGCCGATGGCATCAATCTCGAGCTGATCAATCAGCTGCCGGTGCCAACCACCGTGCACTG
GCATGGCCTGATTCTTCCCAATGCCATGGATGGGGTGCCATTTGTCACCCAACCGCCGATCCCGCCGGGCCAACGCCAAC
GCATCCACTACTCACTGGTGCAAAACGGCACCTTTTGGATGCATTCCCACTACGGCCTGCAGACCCAGAGCTTCGTGGCT
GAGCCCTTTGTGATCCTTGATGCGGAGCAAGAGCAATGGGCTGATCGCACCATCACCGTGATGCTGCGAGATTTCAGCTT
CACCCCGGCTAGCCAGATCCTCAGCAACGTGGTGGCTGGCGAGCGCGGCGGTGGCACAGCCATGGCTAAACGCTTGGCGG
ATTTCCCCTGGCACGAGCCGCGCCCGCTGCTCACCCAGCAATGGGATCCGACAAGCCAACGCTTTGGCTGGAAGCAAGCG
GACGGGGTGCTGATGATGGCTCCCGATGTGGTCTACGACGCGCTGCTGGCCAATGAGCGCAGCCTCGATGATCCCGAAAT
CATTGATGTCGAGCCGGGCGAGACGGTGGCGATTCGCTGGATTGCAGCCAGCGCCTTTATGAGCTTTTTCCTTGATCTCG
GTGAGCTCGAGGGCGAGTTGCTGCGCACCGATGCCAATCCCGTGGAGCCGATTCGCGGCTCGGTGTTTCAACTGGCGTTG
GCGCAGCGCCTCACGCTGCGGCTGACCATGCCCGATACGCCGGGGGTGTTTCCTCTGTTGGCTTTGGGTGAGCGCAGCAA
CTTGCGCTGCGGGGTGGTGCTGCGCAGCAGCCGCAAACTCAAGGCTCCGGCCTTGGCGCCGCAAAGCCAGCAGTGGGCAG
GGTCGTTGGATTTCAGCCAAGACCGGCAACTGCGGGCCAAGACCCCGTTGGCTGTGCGAGCGGCCGACAACACCATCCCT
GTTGCGTTGACTGGCCCTGCCCCCAAATACACCTGGGGCCTCAACCATCGCTTTTACCCCTACCGCGATCCCTATTGGGT
GGACGAGGGCCAGCGGGTGGAGATGGTGTTCACCAACCCCACGCCCATGGGGCATCCCATGCATCTGCATGGCCATGAAT
TCCAGATTTTGGAAATCGATGGTGAGCCTGTGGCCGGACCCATGCGGGACACGGTCTATGTGCCCAAAGGCGGCCGCTGC
CGCATTGCCTTCGATGCCAACAACCCTGGGATCTGGGCCTTCCACTGCCACATCAGCTACCACCACGTGCGCGGCATGTT
CAATGTGGTGGCCTACCGCTCGGCTGACCTGAGCTGGTGGGATCCAGCCGGCTTTGGCCACGAGTATTTGCCTTTTTGA

Upstream 100 bases:

>100_bases
GCGATGGCGAAATGCGAAAGCTTGTTGAGCGTCCACTGGGCAGCCAGAACAGCCATGGCCAGAGGCTGTGATTAGACCGT
GGTGACTGGCTCCGGCGCTC

Downstream 100 bases:

>100_bases
GGAGTTTTTCGTTCGGCTTCCACTCCAGAGCGTTCGGCAGATTTGGCGGCTCTGGTGCCATAGATTAAGGAAATCTGAAG
AAGTAGGTCGAGGCCGTGGA

Product: putative multicopper oxidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 532; Mature: 532

Protein sequence:

>532_residues
MLRRSFLQLGVLGAVIGGASLELFQQAKASARRSWERFIAQPAFQRPRNAATVVLEVATAPITVLGQTVVRGCIRQLNGQ
RGYTTSQADGINLELINQLPVPTTVHWHGLILPNAMDGVPFVTQPPIPPGQRQRIHYSLVQNGTFWMHSHYGLQTQSFVA
EPFVILDAEQEQWADRTITVMLRDFSFTPASQILSNVVAGERGGGTAMAKRLADFPWHEPRPLLTQQWDPTSQRFGWKQA
DGVLMMAPDVVYDALLANERSLDDPEIIDVEPGETVAIRWIAASAFMSFFLDLGELEGELLRTDANPVEPIRGSVFQLAL
AQRLTLRLTMPDTPGVFPLLALGERSNLRCGVVLRSSRKLKAPALAPQSQQWAGSLDFSQDRQLRAKTPLAVRAADNTIP
VALTGPAPKYTWGLNHRFYPYRDPYWVDEGQRVEMVFTNPTPMGHPMHLHGHEFQILEIDGEPVAGPMRDTVYVPKGGRC
RIAFDANNPGIWAFHCHISYHHVRGMFNVVAYRSADLSWWDPAGFGHEYLPF

Sequences:

>Translated_532_residues
MLRRSFLQLGVLGAVIGGASLELFQQAKASARRSWERFIAQPAFQRPRNAATVVLEVATAPITVLGQTVVRGCIRQLNGQ
RGYTTSQADGINLELINQLPVPTTVHWHGLILPNAMDGVPFVTQPPIPPGQRQRIHYSLVQNGTFWMHSHYGLQTQSFVA
EPFVILDAEQEQWADRTITVMLRDFSFTPASQILSNVVAGERGGGTAMAKRLADFPWHEPRPLLTQQWDPTSQRFGWKQA
DGVLMMAPDVVYDALLANERSLDDPEIIDVEPGETVAIRWIAASAFMSFFLDLGELEGELLRTDANPVEPIRGSVFQLAL
AQRLTLRLTMPDTPGVFPLLALGERSNLRCGVVLRSSRKLKAPALAPQSQQWAGSLDFSQDRQLRAKTPLAVRAADNTIP
VALTGPAPKYTWGLNHRFYPYRDPYWVDEGQRVEMVFTNPTPMGHPMHLHGHEFQILEIDGEPVAGPMRDTVYVPKGGRC
RIAFDANNPGIWAFHCHISYHHVRGMFNVVAYRSADLSWWDPAGFGHEYLPF
>Mature_532_residues
MLRRSFLQLGVLGAVIGGASLELFQQAKASARRSWERFIAQPAFQRPRNAATVVLEVATAPITVLGQTVVRGCIRQLNGQ
RGYTTSQADGINLELINQLPVPTTVHWHGLILPNAMDGVPFVTQPPIPPGQRQRIHYSLVQNGTFWMHSHYGLQTQSFVA
EPFVILDAEQEQWADRTITVMLRDFSFTPASQILSNVVAGERGGGTAMAKRLADFPWHEPRPLLTQQWDPTSQRFGWKQA
DGVLMMAPDVVYDALLANERSLDDPEIIDVEPGETVAIRWIAASAFMSFFLDLGELEGELLRTDANPVEPIRGSVFQLAL
AQRLTLRLTMPDTPGVFPLLALGERSNLRCGVVLRSSRKLKAPALAPQSQQWAGSLDFSQDRQLRAKTPLAVRAADNTIP
VALTGPAPKYTWGLNHRFYPYRDPYWVDEGQRVEMVFTNPTPMGHPMHLHGHEFQILEIDGEPVAGPMRDTVYVPKGGRC
RIAFDANNPGIWAFHCHISYHHVRGMFNVVAYRSADLSWWDPAGFGHEYLPF

Specific function: Could be involved in copper resistance. May have oxidase activity [H]

COG id: COG2132

COG function: function code Q; Putative multicopper oxidases

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multicopper oxidase family. CopA subfamily [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323703, Length=482, Percent_Identity=23.8589211618257, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24650186, Length=127, Percent_Identity=33.8582677165354, Blast_Score=79, Evalue=8e-15,

Paralogues:

None

Copy number: 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001117
- InterPro:   IPR011706
- InterPro:   IPR011707
- InterPro:   IPR006376
- InterPro:   IPR002355
- InterPro:   IPR008972
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00394 Cu-oxidase; PF07731 Cu-oxidase_2; PF07732 Cu-oxidase_3 [H]

EC number: NA

Molecular weight: Translated: 59422; Mature: 59422

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS00079 MULTICOPPER_OXIDASE1 ; PS00080 MULTICOPPER_OXIDASE2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRRSFLQLGVLGAVIGGASLELFQQAKASARRSWERFIAQPAFQRPRNAATVVLEVATA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEECCC
PITVLGQTVVRGCIRQLNGQRGYTTSQADGINLELINQLPVPTTVHWHGLILPNAMDGVP
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCC
FVTQPPIPPGQRQRIHYSLVQNGTFWMHSHYGLQTQSFVAEPFVILDAEQEQWADRTITV
CCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCHHHHCCCEEEEECCHHHHCCCEEEE
MLRDFSFTPASQILSNVVAGERGGGTAMAKRLADFPWHEPRPLLTQQWDPTSQRFGWKQA
EEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCC
DGVLMMAPDVVYDALLANERSLDDPEIIDVEPGETVAIRWIAASAFMSFFLDLGELEGEL
CCEEEECHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCCEE
LRTDANPVEPIRGSVFQLALAQRLTLRLTMPDTPGVFPLLALGERSNLRCGVVLRSSRKL
EECCCCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCEEEECCCCCCEEEEEEECCCCC
KAPALAPQSQQWAGSLDFSQDRQLRAKTPLAVRAADNTIPVALTGPAPKYTWGLNHRFYP
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCEEECCCCCCCC
YRDPYWVDEGQRVEMVFTNPTPMGHPMHLHGHEFQILEIDGEPVAGPMRDTVYVPKGGRC
CCCCEECCCCCEEEEEEECCCCCCCEEEECCCEEEEEEECCCCCCCCCCCEEECCCCCEE
RIAFDANNPGIWAFHCHISYHHVRGMFNVVAYRSADLSWWDPAGFGHEYLPF
EEEEECCCCCEEEEEEEEEEHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLRRSFLQLGVLGAVIGGASLELFQQAKASARRSWERFIAQPAFQRPRNAATVVLEVATA
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCHHHHCCCCCEEEEEEECCC
PITVLGQTVVRGCIRQLNGQRGYTTSQADGINLELINQLPVPTTVHWHGLILPNAMDGVP
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEECCCCCEEEEEEEEECCCCCCCCC
FVTQPPIPPGQRQRIHYSLVQNGTFWMHSHYGLQTQSFVAEPFVILDAEQEQWADRTITV
CCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCCHHHHCCCEEEEECCHHHHCCCEEEE
MLRDFSFTPASQILSNVVAGERGGGTAMAKRLADFPWHEPRPLLTQQWDPTSQRFGWKQA
EEECCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHCCCCCC
DGVLMMAPDVVYDALLANERSLDDPEIIDVEPGETVAIRWIAASAFMSFFLDLGELEGEL
CCEEEECHHHHHHHHHCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHHHHHHHHCCCEE
LRTDANPVEPIRGSVFQLALAQRLTLRLTMPDTPGVFPLLALGERSNLRCGVVLRSSRKL
EECCCCCCCCHHHHHHHHHHHCEEEEEEECCCCCCCCCEEEECCCCCCEEEEEEECCCCC
KAPALAPQSQQWAGSLDFSQDRQLRAKTPLAVRAADNTIPVALTGPAPKYTWGLNHRFYP
CCCCCCCCCHHCCCCCCCCCCCCCCCCCCEEEEECCCEEEEEECCCCCCEEECCCCCCCC
YRDPYWVDEGQRVEMVFTNPTPMGHPMHLHGHEFQILEIDGEPVAGPMRDTVYVPKGGRC
CCCCEECCCCCEEEEEEECCCCCCCEEEECCCEEEEEEECCCCCCCCCCCEEECCCCCEE
RIAFDANNPGIWAFHCHISYHHVRGMFNVVAYRSADLSWWDPAGFGHEYLPF
EEEEECCCCCEEEEEEEEEEHHHHHHHHEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12928499 [H]