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The map label for this gene is zraR [H]

Identifier: 147675556

GI number: 147675556

Start: 203173

End: 204507

Strand: Direct

Name: zraR [H]

Synonym: VC0395_A0196

Alternate gene names: 147675556

Gene position: 203173-204507 (Clockwise)

Preceding gene: 147674731

Following gene: 147674721

Centisome position: 6.72

GC content: 48.61

Gene sequence:

>1335_bases
ATGAGCACTCAATTCCGTATGGATTCAGTACCTGGCTCTCTTGTTGTGGTGGGAGGTACCTATGAACCCTGGCTGGCTGT
GTTGGAAAAAGTGGGTTGGCGCTGTACTCAAGTAGCAGATTTGCGCAAAGCCGATGCGTTATTTGTCGAGACTGGGCCAT
GTATTGGTATTGTGGATTTAAGCCATGATGAATTTAGCCTTAACGGGATTGCGAATTTGGTGAGTAGCCATAAGCAAGTC
CGTTGGCTGGCGTTCATTCGTGAGGCGCAGCTCAGTTCAGATACCATTTGCCAATTTATCGTTAACTTCTGTATCGACTT
TTTTACTGCGCCGATCCCTGATGCTCAGTTGTTGAGCACGATTGGTCACCAACTTGGCATGCTGAAGTTGGAAAAGAAAG
TGTGGCCACATTTTGGCTCGGCCGGCAACATGGGCTTGATTGGGGAATCTATGCCTATGAAGCGTTTGCGCGATCAGATC
AAACGCATTGGCCCGACCGATGTCAGTATTTTGATCTATGGCGAAAGTGGTACTGGGAAAGAAACGGTGGCTAAGGCGAT
TCACAAAACATCGTCGCGTGCGCAAAAACCTTTCATTTCAGTTAATTGCCGAGCTATGTCAGAAAAGCGCCTTGAAAGCG
AGCTGTTTGGTCTTGGCGAAACGGAGGAAGGTCAACAACCCTTTTTGCTGCAAGCGGATGGTGGCACACTGCTGCTAAAC
GATATTTTGACCTTGCCTAAAAGCCAACAGTTGAACCTACTGCGTTTCTTACAAGAAGGGACTGTGGAGACGCGCCAAGG
GGTTCGTGCAGTCGATGTGCGTATTTTGGCCGCCAATTCGTCAGACATCGAAAAAGCGCTGATCGATGGTGATTTTAACG
AAGAGTTGTACCACTACATTAACGTATTGCGGATTAATGTGCCTAGTTTGAAAGAGCGCGCATCGGATATCGTGCTACTG
GCTAAACACTTTTTGCAAGAATACTCCAAAGAGTACAACGCTCAGGCGCGTAGCTTCTCTGATGATGCCGTACGTGGGTT
AACTCGCTACCATTGGCCGGGTAATGTGCGTGAGCTGATGAACCAGATCAAGCGTGTGGTATTAATGTCAGATACTGTGG
TGCTGGATGAATCTCAGCTCGATCTTCCCAAGCGCAGCGATGGCCGTCGCAGCCTGAAAAGCATTCGGGAACGCTCCGAG
CGTGATGCACTGTTGCTGGTGTTGGAGTCGCACTCTGGGCAAGTTTCAACGGCAGCCAAAGAGCTGGGAGTATCGCGTGC
AACCATGTATCGCTTACTGAATAAACACAACTTGATCACCGATGAAAACTTCTAA

Upstream 100 bases:

>100_bases
ATTCTAGTGCAAAGTCTCGCTAATGTAACGTCCGTAACCATGTAGTGGGTGCGAATAGAATAATCCGCATCGTAACAATA
AAAATAAGGAATATAGGTTC

Downstream 100 bases:

>100_bases
GTTTTGCTGATTTACCTTGTACTCATGTTCAGCCACTTGGTTAAGTGGCTGAATTTTTTGTAGTACAGACTGTTTTTGGG
ACGCCTTTCTACAGCGAATT

Product: sigma-54 dependent transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 444; Mature: 443

Protein sequence:

>444_residues
MSTQFRMDSVPGSLVVVGGTYEPWLAVLEKVGWRCTQVADLRKADALFVETGPCIGIVDLSHDEFSLNGIANLVSSHKQV
RWLAFIREAQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLEKKVWPHFGSAGNMGLIGESMPMKRLRDQI
KRIGPTDVSILIYGESGTGKETVAKAIHKTSSRAQKPFISVNCRAMSEKRLESELFGLGETEEGQQPFLLQADGGTLLLN
DILTLPKSQQLNLLRFLQEGTVETRQGVRAVDVRILAANSSDIEKALIDGDFNEELYHYINVLRINVPSLKERASDIVLL
AKHFLQEYSKEYNAQARSFSDDAVRGLTRYHWPGNVRELMNQIKRVVLMSDTVVLDESQLDLPKRSDGRRSLKSIRERSE
RDALLLVLESHSGQVSTAAKELGVSRATMYRLLNKHNLITDENF

Sequences:

>Translated_444_residues
MSTQFRMDSVPGSLVVVGGTYEPWLAVLEKVGWRCTQVADLRKADALFVETGPCIGIVDLSHDEFSLNGIANLVSSHKQV
RWLAFIREAQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLEKKVWPHFGSAGNMGLIGESMPMKRLRDQI
KRIGPTDVSILIYGESGTGKETVAKAIHKTSSRAQKPFISVNCRAMSEKRLESELFGLGETEEGQQPFLLQADGGTLLLN
DILTLPKSQQLNLLRFLQEGTVETRQGVRAVDVRILAANSSDIEKALIDGDFNEELYHYINVLRINVPSLKERASDIVLL
AKHFLQEYSKEYNAQARSFSDDAVRGLTRYHWPGNVRELMNQIKRVVLMSDTVVLDESQLDLPKRSDGRRSLKSIRERSE
RDALLLVLESHSGQVSTAAKELGVSRATMYRLLNKHNLITDENF
>Mature_443_residues
STQFRMDSVPGSLVVVGGTYEPWLAVLEKVGWRCTQVADLRKADALFVETGPCIGIVDLSHDEFSLNGIANLVSSHKQVR
WLAFIREAQLSSDTICQFIVNFCIDFFTAPIPDAQLLSTIGHQLGMLKLEKKVWPHFGSAGNMGLIGESMPMKRLRDQIK
RIGPTDVSILIYGESGTGKETVAKAIHKTSSRAQKPFISVNCRAMSEKRLESELFGLGETEEGQQPFLLQADGGTLLLND
ILTLPKSQQLNLLRFLQEGTVETRQGVRAVDVRILAANSSDIEKALIDGDFNEELYHYINVLRINVPSLKERASDIVLLA
KHFLQEYSKEYNAQARSFSDDAVRGLTRYHWPGNVRELMNQIKRVVLMSDTVVLDESQLDLPKRSDGRRSLKSIRERSER
DALLLVLESHSGQVSTAAKELGVSRATMYRLLNKHNLITDENF

Specific function: Member of the two-component regulatory system zraS/zraR. When activated by zraS it acts in conjunction with sigma-54 to regulate the expression of zraP. Positively autoregulates the expression of the zraSR operon [H]

COG id: COG1221

COG function: function code KT; Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1790437, Length=387, Percent_Identity=33.3333333333333, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI1788905, Length=341, Percent_Identity=35.4838709677419, Blast_Score=202, Evalue=4e-53,
Organism=Escherichia coli, GI1788550, Length=424, Percent_Identity=34.6698113207547, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1789233, Length=325, Percent_Identity=34.4615384615385, Blast_Score=178, Evalue=6e-46,
Organism=Escherichia coli, GI1790299, Length=329, Percent_Identity=35.8662613981763, Blast_Score=175, Evalue=4e-45,
Organism=Escherichia coli, GI87082117, Length=316, Percent_Identity=36.7088607594937, Blast_Score=173, Evalue=2e-44,
Organism=Escherichia coli, GI1787583, Length=310, Percent_Identity=33.5483870967742, Blast_Score=161, Evalue=9e-41,
Organism=Escherichia coli, GI87082152, Length=325, Percent_Identity=32.6153846153846, Blast_Score=159, Evalue=4e-40,
Organism=Escherichia coli, GI1789087, Length=302, Percent_Identity=35.4304635761589, Blast_Score=158, Evalue=6e-40,
Organism=Escherichia coli, GI1786524, Length=315, Percent_Identity=33.3333333333333, Blast_Score=154, Evalue=2e-38,
Organism=Escherichia coli, GI87081872, Length=318, Percent_Identity=32.3899371069182, Blast_Score=151, Evalue=1e-37,
Organism=Escherichia coli, GI87081858, Length=284, Percent_Identity=29.5774647887324, Blast_Score=119, Evalue=6e-28,
Organism=Escherichia coli, GI1789828, Length=251, Percent_Identity=25.4980079681275, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR020441
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 49716; Mature: 49584

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: PS00675 SIGMA54_INTERACT_1 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQFRMDSVPGSLVVVGGTYEPWLAVLEKVGWRCTQVADLRKADALFVETGPCIGIVDL
CCCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCEEEEEEC
SHDEFSLNGIANLVSSHKQVRWLAFIREAQLSSDTICQFIVNFCIDFFTAPIPDAQLLST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IGHQLGMLKLEKKVWPHFGSAGNMGLIGESMPMKRLRDQIKRIGPTDVSILIYGESGTGK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCH
ETVAKAIHKTSSRAQKPFISVNCRAMSEKRLESELFGLGETEEGQQPFLLQADGGTLLLN
HHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEH
DILTLPKSQQLNLLRFLQEGTVETRQGVRAVDVRILAANSSDIEKALIDGDFNEELYHYI
HHHCCCCCCCHHHHHHHHHCCHHHHCCCEEEEEEEEECCCCHHHHHHHCCCCHHHHHHHH
NVLRINVPSLKERASDIVLLAKHFLQEYSKEYNAQARSFSDDAVRGLTRYHWPGNVRELM
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCHHHHHH
NQIKRVVLMSDTVVLDESQLDLPKRSDGRRSLKSIRERSERDALLLVLESHSGQVSTAAK
HHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ELGVSRATMYRLLNKHNLITDENF
HHCCHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
STQFRMDSVPGSLVVVGGTYEPWLAVLEKVGWRCTQVADLRKADALFVETGPCIGIVDL
CCCCCCCCCCCCEEEECCCCHHHHHHHHHHCCHHHHHHHHHHCCEEEEECCCEEEEEEC
SHDEFSLNGIANLVSSHKQVRWLAFIREAQLSSDTICQFIVNFCIDFFTAPIPDAQLLST
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCHHHHHH
IGHQLGMLKLEKKVWPHFGSAGNMGLIGESMPMKRLRDQIKRIGPTDVSILIYGESGTGK
HHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCH
ETVAKAIHKTSSRAQKPFISVNCRAMSEKRLESELFGLGETEEGQQPFLLQADGGTLLLN
HHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCCEEEEECCCEEEEH
DILTLPKSQQLNLLRFLQEGTVETRQGVRAVDVRILAANSSDIEKALIDGDFNEELYHYI
HHHCCCCCCCHHHHHHHHHCCHHHHCCCEEEEEEEEECCCCHHHHHHHCCCCHHHHHHHH
NVLRINVPSLKERASDIVLLAKHFLQEYSKEYNAQARSFSDDAVRGLTRYHWPGNVRELM
HHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCHHHHHHHHHCCCCCHHHHHH
NQIKRVVLMSDTVVLDESQLDLPKRSDGRRSLKSIRERSERDALLLVLESHSGQVSTAAK
HHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHH
ELGVSRATMYRLLNKHNLITDENF
HHCCHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]