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The map label for this gene is recD [H]

Identifier: 147674978

GI number: 147674978

Start: 2019860

End: 2021980

Strand: Reverse

Name: recD [H]

Synonym: VC0395_A1903

Alternate gene names: 147674978

Gene position: 2021980-2019860 (Counterclockwise)

Preceding gene: 147674146

Following gene: 147673802

Centisome position: 66.86

GC content: 52.48

Gene sequence:

>2121_bases
ATGATGTTTTGGGATAGTGAAGTAGCGAAACGTCTGCTGGCACAAGGCGCGCTGCGTCCTTTGGATGTGCAGTTTGCCCG
CTTTATTGGCAAGCAAGCCGCATTGGCAGGGCACAACGCTGCAGAAAGTGAACTGTTGAGTGTGCTGAGCGCGGCGCTCA
GTGCAGAACTTGGGCGTGGACACATCTGTTTGCCACTGTGGGATGCACAGGGTAATCGCTGCGATCTGGCGGCGCTGATT
GGTCTTTATGGTGAAGCGAGTTTGCAGCACAGTGAACGCTGGTTAGCGTTAGACTGGCAAGCCTTACTGCAAGCCTCGCC
GTTGGTGGGGAAGCAAGGTGAAGCGGTGCCGTTAATGTTTGATGGCGCAAGGCTCTATCTGCATCGCTACTGGCATTATG
AAAAGCAACTGGCAGCGCGATTGACTGAGTTGGCCGCACCCCAACGTTTAAGCCCTGCTGAACTGGCTAACTTGCGTGAA
CGCCTGAATACCTTATTTGCCCGCGACTATTTAGGCTTGTGGCAAGCACTACAACAAAAGCCGCTGAGTTCGGTCGAGCG
GATTCAACTGCTGAATGATCGATTGGATGTGGTGGAGTCGGATGCGCTGGATTGGCCAGCGATTGAAGCTGTAGTCGAAA
AAGCGCAGCGTGCCGCGGATTTGCAAGCTTTAGAGCAGCTTATTCCGCTTACTCACTGCTTAAACTGGCAAAAAGTGGCG
GCTGCCGTCGCGCTCACGCGCCGTTTTGCGGTGATTTCCGGTGGGCCGGGAACCGGCAAAACCACCACAGTGACCAAGCT
TCTGGCGGCGCTGATTAGCCAAAGCATGGCGCAAGGTAAAGTGCCAGAGATCAAATTGATTGCTCCAACCGGTAAAGCCG
CGGCACGCTTAACCGAATCGATGGGTAAAGCGGTGAGTCAGCTGGCGATAGAGCCTGAGATCGCCGCGGCGATCCCAAGC
ACTTCCAGTACCATTCACCGTTTGCTTGGCGCGATTCCGGGCAGCGCTGAGTTTCGTCATCATGCACGTAATCCACTCCA
TCTTGATCTGTTGGTGGTGGATGAAGCGTCCATGGTCGATCTGCCTTTGATGGTGAAACTGGTCGAAGCGCTGCCCAAGC
ACGCTCGGTTGATTTTACTTGGCGATAAAGATCAGTTGGCCTCGGTAGAAGCGGGGGCGGTGCTCGGTGATATTTGTACC
TTCCTGAACCAAGGTTACGGTAATGAGCAGGGCGCGCAGTTGGCTGAACTGACGGGGTTTGCCTCTTTGCGCCAAACTGC
CAGTAAGACGGTGAATCCGGTGGCGGATTGCTTATGCATGCTGCAAAAAAGCTACCGTTTTGATGCACGTTCTGGCATTG
GCCAACTGGCGAAAGCGATCAACAGTGGATCTCCGGCGCGCGTTGAAACTGTGTGGCAGCAATCGTTCAGCGATATTGAA
CATTTTGCCCTTAGTGGCGAGCATTATCAGCAACTGCTGCAAACCTTAGTGCAGGCTTATCGTCCTTATCTGAATTTGCT
CAATCAATCGACTGAGCAGTTTGAGTCGACAAAGCAAACCATGCTCACACTAGCCAAATCAGCACTCGATGCGTTTAGTC
GCTGCCGATTATTGTGCGCGTTACGTGAAGGCGATTTTGGGGTGATGGGGCTGAACACTCGCATCGAACGGGCGTTGAAT
GCGCACAAGCTGATTAAAACTCAAGAAGAGATCTGGTATCACGGGCGACCGATCATGGTCACGCGTAACGATCATGGCTT
GGGGCTATACAATGGTGATATCGGTTTGTGTATGCGCGATCGTGACGATGATCAGGGCAGACTGAAAGTCTATTTTGAGC
TGCCGGATGGCAGCATTAAAGCCGTGTTACCGAGCCGAGTCCCGCAACATGAAACCGCGTATGCGATGACCATACATAAA
TCGCAAGGCAGCGAATTTGATTTAACTTTGCTGATTTTACCGCCGGATTACAGTCCGATTCTGACGCGTGAGTTAGTTTA
CACGGGGATCACAAGGGCGAAAAAACAGCTCAAATTGTATTGCGATAACAAGGTATTGCAGCGGGCAATTAAAGTGAAAA
CCCAACGGGCGAGTGGCTTAGTGGCAAGGTTGGAGCAGTAA

Upstream 100 bases:

>100_bases
CCAAGCCAAGCTTGGCCTTGTTAGATGAGTTGGATGGATTGATTGCAGGGCGCGAGCTGGCACAAAGAGCGAGTAAAGCT
GGGCAGATGGAGCTTGATTT

Downstream 100 bases:

>100_bases
ATGCTCCGCCATTCCGTGGCGGCACAGCATTAAAGGTTGGCAAAAGCTTTAGTAAAGGTGATGCTGCGGATCTGGTAACG
TTCACGCGATTGGAGCAGAA

Product: exodeoxyribonuclease V, 67 kDa subunit

Products: NA

Alternate protein names: Exodeoxyribonuclease V 67 kDa polypeptide [H]

Number of amino acids: Translated: 706; Mature: 706

Protein sequence:

>706_residues
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAALAGHNAAESELLSVLSAALSAELGRGHICLPLWDAQGNRCDLAALI
GLYGEASLQHSERWLALDWQALLQASPLVGKQGEAVPLMFDGARLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRE
RLNTLFARDYLGLWQALQQKPLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTESMGKAVSQLAIEPEIAAAIPS
TSSTIHRLLGAIPGSAEFRHHARNPLHLDLLVVDEASMVDLPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICT
FLNQGYGNEQGAQLAELTGFASLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVETVWQQSFSDIE
HFALSGEHYQQLLQTLVQAYRPYLNLLNQSTEQFESTKQTMLTLAKSALDAFSRCRLLCALREGDFGVMGLNTRIERALN
AHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHK
SQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ

Sequences:

>Translated_706_residues
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAALAGHNAAESELLSVLSAALSAELGRGHICLPLWDAQGNRCDLAALI
GLYGEASLQHSERWLALDWQALLQASPLVGKQGEAVPLMFDGARLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRE
RLNTLFARDYLGLWQALQQKPLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTESMGKAVSQLAIEPEIAAAIPS
TSSTIHRLLGAIPGSAEFRHHARNPLHLDLLVVDEASMVDLPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICT
FLNQGYGNEQGAQLAELTGFASLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVETVWQQSFSDIE
HFALSGEHYQQLLQTLVQAYRPYLNLLNQSTEQFESTKQTMLTLAKSALDAFSRCRLLCALREGDFGVMGLNTRIERALN
AHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHK
SQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ
>Mature_706_residues
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAALAGHNAAESELLSVLSAALSAELGRGHICLPLWDAQGNRCDLAALI
GLYGEASLQHSERWLALDWQALLQASPLVGKQGEAVPLMFDGARLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRE
RLNTLFARDYLGLWQALQQKPLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTESMGKAVSQLAIEPEIAAAIPS
TSSTIHRLLGAIPGSAEFRHHARNPLHLDLLVVDEASMVDLPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICT
FLNQGYGNEQGAQLAELTGFASLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVETVWQQSFSDIE
HFALSGEHYQQLLQTLVQAYRPYLNLLNQSTEQFESTKQTMLTLAKSALDAFSRCRLLCALREGDFGVMGLNTRIERALN
AHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRDRDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHK
SQGSEFDLTLLILPPDYSPILTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ

Specific function: Exhibits several catalytic activities, including ATP- dependent exonuclease, ATP-stimulated endonuclease, ATP-dependent unwinding and DNA-dependent ATPase activities. Strand cleavage occurs 5' to 3' during the unwinding of duplex DNA at CHI sequences, whi

COG id: COG0507

COG function: function code L; ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the recD family [H]

Homologues:

Organism=Escherichia coli, GI1789182, Length=690, Percent_Identity=46.231884057971, Blast_Score=510, Evalue=1e-145,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007807
- InterPro:   IPR006344
- InterPro:   IPR000606 [H]

Pfam domain/function: PF05127 DUF699; PF01443 Viral_helicase1 [H]

EC number: =3.1.11.5 [H]

Molecular weight: Translated: 77796; Mature: 77796

Theoretical pI: Translated: 8.12; Mature: 8.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAALAGHNAAESELLSVLSAALSAELGRG
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
HICLPLWDAQGNRCDLAALIGLYGEASLQHSERWLALDWQALLQASPLVGKQGEAVPLMF
EEEEEEECCCCCCCHHHHHHHHHCCCHHHCCCCEEEEEHHHHHCCCCCCCCCCCEEEEEE
DGARLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRERLNTLFARDYLGLWQALQQK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTES
HHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
MGKAVSQLAIEPEIAAAIPSTSSTIHRLLGAIPGSAEFRHHARNPLHLDLLVVDEASMVD
HHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEEECCCCCCC
LPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICTFLNQGYGNEQGAQLAELTGF
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ASLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVETVWQQSFSDIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HFALSGEHYQQLLQTLVQAYRPYLNLLNQSTEQFESTKQTMLTLAKSALDAFSRCRLLCA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREGDFGVMGLNTRIERALNAHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRD
EECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCEEEEEEC
RDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHKSQGSEFDLTLLILPPDYSPI
CCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHH
LTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMFWDSEVAKRLLAQGALRPLDVQFARFIGKQAALAGHNAAESELLSVLSAALSAELGRG
CCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCC
HICLPLWDAQGNRCDLAALIGLYGEASLQHSERWLALDWQALLQASPLVGKQGEAVPLMF
EEEEEEECCCCCCCHHHHHHHHHCCCHHHCCCCEEEEEHHHHHCCCCCCCCCCCEEEEEE
DGARLYLHRYWHYEKQLAARLTELAAPQRLSPAELANLRERLNTLFARDYLGLWQALQQK
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PLSSVERIQLLNDRLDVVESDALDWPAIEAVVEKAQRAADLQALEQLIPLTHCLNWQKVA
CHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AAVALTRRFAVISGGPGTGKTTTVTKLLAALISQSMAQGKVPEIKLIAPTGKAAARLTES
HHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHH
MGKAVSQLAIEPEIAAAIPSTSSTIHRLLGAIPGSAEFRHHARNPLHLDLLVVDEASMVD
HHHHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCHHHHHHCCCCEEEEEEEECCCCCCC
LPLMVKLVEALPKHARLILLGDKDQLASVEAGAVLGDICTFLNQGYGNEQGAQLAELTGF
HHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHH
ASLRQTASKTVNPVADCLCMLQKSYRFDARSGIGQLAKAINSGSPARVETVWQQSFSDIE
HHHHHHHHHHHHHHHHHHHHHHHHCCCCHHCCHHHHHHHHCCCCCHHHHHHHHHHHHHHH
HFALSGEHYQQLLQTLVQAYRPYLNLLNQSTEQFESTKQTMLTLAKSALDAFSRCRLLCA
HHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LREGDFGVMGLNTRIERALNAHKLIKTQEEIWYHGRPIMVTRNDHGLGLYNGDIGLCMRD
EECCCEEEEECCHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEECCEEEEEEC
RDDDQGRLKVYFELPDGSIKAVLPSRVPQHETAYAMTIHKSQGSEFDLTLLILPPDYSPI
CCCCCCEEEEEEECCCCCEEEECCCCCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCHH
LTRELVYTGITRAKKQLKLYCDNKVLQRAIKVKTQRASGLVARLEQ
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3537961; 9278503; 3537960 [H]