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The map label for this gene is dapB

Identifier: 147674435

GI number: 147674435

Start: 2112150

End: 2112959

Strand: Reverse

Name: dapB

Synonym: VC0395_A1970

Alternate gene names: 147674435

Gene position: 2112959-2112150 (Counterclockwise)

Preceding gene: 147674265

Following gene: 147675544

Centisome position: 69.87

GC content: 50.74

Gene sequence:

>810_bases
ATGGTTAGAATTGCGATTGCGGGTGCCGCAGGACGTATGGGACGCAATCTGGTAAAAGCAACACACCAGAATCCGCTTTC
CGAATTGGGCGCGGGCTCTGAGCGTCCAGAATCCTCATTAGTGGGCGTTGATATTGGTGAGCTGTGCGGTATTGGTAAAC
AAGGTATTGTTTTAGTTGATAACCTAGAGCAAGCCGTTGAGCAGTTTGATGTGATTATTGATTTCACTGCGCCTGCCAGC
ACCTTAGCTAACTTAGCTTTGTGTGAGCAGCATGGTAAAAAACTGGTGATTGGCACAACGGGCTTTACCGATGCTCAGCG
CCAAACCATTGAACAAGCAGCAAAGAAGATCCCGATTGTCATGGCGCCCAACTACAGCGTTGGTGTCAACTTGGTGTTTA
AACTGCTGGAAAAAGCCGCCAAAGTGATGGGTGACTACTGTGATATCGAAATCATTGAAGCTCATCATCGCCATAAAGTC
GATGCGCCTTCGGGTACCGCGATTGGCATGGGCGAAGCGATTGCCCATGCGATGGGTAATCAACTGAGTGATGTGGCGGT
GTACGCGCGAGAAGGGATCACCGGTGAGCGTTCACGCAATGAAATTGGGTTTGCCACGATTCGTGCGGGAGACATCATTG
GTGAGCATACCGCCATGTTTGCCGATATTGGTGAGCGAGTGGAGATCACCCACAAAGCCACTGACCGAATGACGTTTGCC
AATGGTGCAGTCAAAGCCGCCATTTGGCTCGCGGAGCAACCCGCCGGTTTCTACACCATGACCGATGTGCTCGGATTGAA
TGATCTCTAA

Upstream 100 bases:

>100_bases
GCTTGGCCAAGTCGTGAGGCTAGCCAGAGTGGAAGATAGTTGGTAGTTTAAGTCTACAAATTGGAACTGCCTCAAGGCAG
TGGAGAATGGAGACAGCAAG

Downstream 100 bases:

>100_bases
ATACATAATTATGCGCCAGCGAACTGCTGGCGTTTTTTTTATCCTTAAAACTTGATTAAAAATCTTCTCATCCATTTTCA
GCGAAAGCTAAGCTTGTTTT

Product: dihydrodipicolinate reductase

Products: NA

Alternate protein names: DHPR

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MVRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVDNLEQAVEQFDVIIDFTAPAS
TLANLALCEQHGKKLVIGTTGFTDAQRQTIEQAAKKIPIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKV
DAPSGTAIGMGEAIAHAMGNQLSDVAVYAREGITGERSRNEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
NGAVKAAIWLAEQPAGFYTMTDVLGLNDL

Sequences:

>Translated_269_residues
MVRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVDNLEQAVEQFDVIIDFTAPAS
TLANLALCEQHGKKLVIGTTGFTDAQRQTIEQAAKKIPIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKV
DAPSGTAIGMGEAIAHAMGNQLSDVAVYAREGITGERSRNEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
NGAVKAAIWLAEQPAGFYTMTDVLGLNDL
>Mature_269_residues
MVRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVDNLEQAVEQFDVIIDFTAPAS
TLANLALCEQHGKKLVIGTTGFTDAQRQTIEQAAKKIPIVMAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKV
DAPSGTAIGMGEAIAHAMGNQLSDVAVYAREGITGERSRNEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
NGAVKAAIWLAEQPAGFYTMTDVLGLNDL

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; second step. [C]

COG id: COG0289

COG function: function code E; Dihydrodipicolinate reductase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydrodipicolinate reductase family

Homologues:

Organism=Escherichia coli, GI1786214, Length=268, Percent_Identity=64.1791044776119, Blast_Score=338, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DAPB_VIBC3 (A5F5N9)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F5N9
- SMR:   A5F5N9
- STRING:   A5F5N9
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1970
- eggNOG:   COG0289
- HOGENOM:   HBG594002
- OMA:   GALKACE
- ProtClustDB:   PRK00048
- BioCyc:   VCHO345073:VC0395_A1970-MONOMER
- GO:   GO:0005737
- GO:   GO:0005488
- HAMAP:   MF_00102
- InterPro:   IPR022663
- InterPro:   IPR000846
- InterPro:   IPR022664
- InterPro:   IPR011770
- InterPro:   IPR016040
- Gene3D:   G3DSA:3.40.50.720
- PANTHER:   PTHR20836
- TIGRFAMs:   TIGR00036

Pfam domain/function: PF05173 DapB_C; PF01113 DapB_N

EC number: =1.3.1.26

Molecular weight: Translated: 28607; Mature: 28607

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS01298 DAPB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVD
CEEEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCEECCCHHHHHCCCCCCEEEEH
NLEQAVEQFDVIIDFTAPASTLANLALCEQHGKKLVIGTTGFTDAQRQTIEQAAKKIPIV
HHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCEE
MAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKVDAPSGTAIGMGEAIAHAMGN
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCCCCCHHHHHHHHHCC
QLSDVAVYAREGITGERSRNEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
CHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEHHCCCEEEC
NGAVKAAIWLAEQPAGFYTMTDVLGLNDL
CCCEEEEEEEECCCCCCEEHHHHHCCCCC
>Mature Secondary Structure
MVRIAIAGAAGRMGRNLVKATHQNPLSELGAGSERPESSLVGVDIGELCGIGKQGIVLVD
CEEEEEECCCCHHHHHHHHHHCCCCHHHHCCCCCCCCCCEECCCHHHHHCCCCCCEEEEH
NLEQAVEQFDVIIDFTAPASTLANLALCEQHGKKLVIGTTGFTDAQRQTIEQAAKKIPIV
HHHHHHHHHEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHCCEE
MAPNYSVGVNLVFKLLEKAAKVMGDYCDIEIIEAHHRHKVDAPSGTAIGMGEAIAHAMGN
ECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEEECHHCCCCCCCCCCCCCHHHHHHHHHCC
QLSDVAVYAREGITGERSRNEIGFATIRAGDIIGEHTAMFADIGERVEITHKATDRMTFA
CHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHCCCEEEEEEHHCCCEEEC
NGAVKAAIWLAEQPAGFYTMTDVLGLNDL
CCCEEEEEEEECCCCCCEEHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA