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The map label for this gene is ftsW [H]

Identifier: 147674339

GI number: 147674339

Start: 2124248

End: 2125444

Strand: Reverse

Name: ftsW [H]

Synonym: VC0395_A1980

Alternate gene names: 147674339

Gene position: 2125444-2124248 (Counterclockwise)

Preceding gene: 147674702

Following gene: 147675068

Centisome position: 70.28

GC content: 48.29

Gene sequence:

>1197_bases
TTGTTTTTATCCGGATCTTTCACAAAACTGAGCCACTGGTTGAGAACCTCCTCACCAGAGGCGCTGTTTGACCGTCAATT
GGTCTGGATTGCTTTTGGCTTGATGCTGATTGGTTTGGTGATGGTGACATCAGCCTCATTTCCCATCAGTTCTCGCCTAA
CCGATCAACCGTTTCACTTTATGTTTCGTCACGCCATCTTTCTGCTGTTGGCTTTTCTCACCTCAAGCATGGTGTTACAA
GTCCCTCTAGATCGTTGGATGAAATACAGCTCGTTACTACTCGGCATCTCCTTTTTCTTATTGATTGTCGTACTGGTCGT
GGGCAAATCGGTCAACGGTGCATCACGTTGGATCCCGCTCGGTCTTTTTAACCTTCAGCCAGCGGAAGTGGCTAAGCTGT
CACTGTTTATCTTTATGTCCGGTTATCTGGTGCGCAAGCATGATGAAGTACGACAGACTTTCTTTGGCGGCTTTTTAAAA
CCTATCATGGTGTTTGGTACGCTCGCGGTGTTGCTGCTCGGTCAGCCGGACTTAGGTACCGTGATCGTAATGCTGGTGAC
ACTGTTTGGCATGCTGTTTATTGCCGGCGCGAAACTCTCTCAGTTTTTGGCCTTGATGGTGGCAGGAGTGTTAGCGGTGG
TCGCGCTGATTGTCGCTGAACCTTATCGTGTACGCCGTGTAACCTCGTTTTTAGATCCGTGGGAAGATCCCTTTGGTAGC
GGTTACCAGCTGACTCAATCCTTGATGGCGTTTGGCCGCGGTGAGTGGTTTGGTCAAGGATTAGGCAATTCGATTCAAAA
ACTCGAATATTTGCCTGAAGCGCATACTGACTTTGTATTCGCCGTCTTGGCCGAAGAGCTTGGCTTTATCGGCGTGGTAT
TAGTGCTCGTGCTGATTTTCAGTTTGGTACTGAAAGCGATTTTTATCGGCAAAAAAGCCTTTCAACATGATCAGCAGTTT
GGCGGCTACCTCGCGTTTGGCATCGGTATTTGGTTTGCGTTTCAGACCTTAGTGAACGTCGGTGCGGCAGCGGGTATGGT
GCCCACCAAAGGCTTGACCTTACCACTGATCAGTTACGGTGGTTCCAGTTTAATTATTATGTCAGTGGCGGTGTCGATTT
TACTGCGCATCGATCATGAATGCCGTTTAGCGGATCGCCACGCACCAGAAGAAATCACAGTTGATGAACAAGAATAA

Upstream 100 bases:

>100_bases
CCCGCTTGTGCGAGCTTTGATCAGTTCAAAAACTTTATGGCGCGTGGGGATATTTTTGCCCAACTCGCTCGGCAATATGC
ATAAGCGTTAGGTAAGTCAC

Downstream 100 bases:

>100_bases
AAAATTAATGGTGATGGCCGGAGGAACCGGCGGTCACGTATTTCCCGGTTTGGCTGTCGCCAAACAACTACAGCAACAGG
GTTGGCAAATTCGTTGGTTG

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 398

Protein sequence:

>398_residues
MFLSGSFTKLSHWLRTSSPEALFDRQLVWIAFGLMLIGLVMVTSASFPISSRLTDQPFHFMFRHAIFLLLAFLTSSMVLQ
VPLDRWMKYSSLLLGISFFLLIVVLVVGKSVNGASRWIPLGLFNLQPAEVAKLSLFIFMSGYLVRKHDEVRQTFFGGFLK
PIMVFGTLAVLLLGQPDLGTVIVMLVTLFGMLFIAGAKLSQFLALMVAGVLAVVALIVAEPYRVRRVTSFLDPWEDPFGS
GYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFIGVVLVLVLIFSLVLKAIFIGKKAFQHDQQF
GGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLIIMSVAVSILLRIDHECRLADRHAPEEITVDEQE

Sequences:

>Translated_398_residues
MFLSGSFTKLSHWLRTSSPEALFDRQLVWIAFGLMLIGLVMVTSASFPISSRLTDQPFHFMFRHAIFLLLAFLTSSMVLQ
VPLDRWMKYSSLLLGISFFLLIVVLVVGKSVNGASRWIPLGLFNLQPAEVAKLSLFIFMSGYLVRKHDEVRQTFFGGFLK
PIMVFGTLAVLLLGQPDLGTVIVMLVTLFGMLFIAGAKLSQFLALMVAGVLAVVALIVAEPYRVRRVTSFLDPWEDPFGS
GYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFIGVVLVLVLIFSLVLKAIFIGKKAFQHDQQF
GGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLIIMSVAVSILLRIDHECRLADRHAPEEITVDEQE
>Mature_398_residues
MFLSGSFTKLSHWLRTSSPEALFDRQLVWIAFGLMLIGLVMVTSASFPISSRLTDQPFHFMFRHAIFLLLAFLTSSMVLQ
VPLDRWMKYSSLLLGISFFLLIVVLVVGKSVNGASRWIPLGLFNLQPAEVAKLSLFIFMSGYLVRKHDEVRQTFFGGFLK
PIMVFGTLAVLLLGQPDLGTVIVMLVTLFGMLFIAGAKLSQFLALMVAGVLAVVALIVAEPYRVRRVTSFLDPWEDPFGS
GYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFIGVVLVLVLIFSLVLKAIFIGKKAFQHDQQF
GGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYGGSSLIIMSVAVSILLRIDHECRLADRHAPEEITVDEQE

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=386, Percent_Identity=61.3989637305699, Blast_Score=462, Evalue=1e-131,
Organism=Escherichia coli, GI1786853, Length=310, Percent_Identity=32.5806451612903, Blast_Score=147, Evalue=1e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 43959; Mature: 43959

Theoretical pI: Translated: 7.82; Mature: 7.82

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLSGSFTKLSHWLRTSSPEALFDRQLVWIAFGLMLIGLVMVTSASFPISSRLTDQPFHF
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHH
MFRHAIFLLLAFLTSSMVLQVPLDRWMKYSSLLLGISFFLLIVVLVVGKSVNGASRWIPL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEE
GLFNLQPAEVAKLSLFIFMSGYLVRKHDEVRQTFFGGFLKPIMVFGTLAVLLLGQPDLGT
EECCCCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
VIVMLVTLFGMLFIAGAKLSQFLALMVAGVLAVVALIVAEPYRVRRVTSFLDPWEDPFGS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCC
GYQLTQSLMAFGRGEWFGQGLGNSIQKLEYLPEAHTDFVFAVLAEELGFIGVVLVLVLIF
CHHHHHHHHHHCCCCHHHHHCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLVLKAIFIGKKAFQHDQQFGGYLAFGIGIWFAFQTLVNVGAAAGMVPTKGLTLPLISYG
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCC
GSSLIIMSVAVSILLRIDHECRLADRHAPEEITVDEQE
CCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHCCCHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]