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The map label for this gene is dinP

Identifier: 147674154

GI number: 147674154

Start: 1995674

End: 1996756

Strand: Reverse

Name: dinP

Synonym: VC0395_A1876

Alternate gene names: 147674154

Gene position: 1996756-1995674 (Counterclockwise)

Preceding gene: 147673696

Following gene: 147674779

Centisome position: 66.03

GC content: 46.91

Gene sequence:

>1083_bases
ATGCAAGACAGAATTCGTAAAATCATCCATGTCGATATGGACTGCTTTTTCGCTGCCGTTGAAATGCGGGATAACCCTGC
GTATCGAGAGATAGCACTGGCCGTGGGCGGACATGAAAAGCAGCGTGGAGTGATCAGTACATGCAACTATCAGGCGCGCA
AATTTGGCGTTCGTTCTGCTATGCCTACCGCTCAGGCATTAAAACTCTGCCCACAACTGCATGTCGTCCCGGGGCGGATG
TCTGTCTACAAAAGTGTTTCTCAACAAATCCAAACTATTTTTCAGCGTTATACCTCGTTGATTGAGCCTCTTTCACTTGA
TGAGGCCTATCTTGATGTCAGTGAATCGACTGCCTATCAAGGTAGTGCGACCTTAATTGCTCAAGCGATTCGACGTGATA
TCTGGCAAGAGTTGAATTTAACGGCGTCCGCTGGTGTTGCGCCGATCAAGTTTCTTGCAAAAGTTGCGTCCGACTTAAAT
AAACCTAATGGCTTGTATGTGGTGACGCCTGACAAAGTTCAGGAGATGGTCGATAGTTTGCCGCTGGAAAAGATTCCGGG
TGTTGGCAAAGTGGCGTTAGAAAAGCTGCATCAAGCCGGTCTTTATGTCGGAGCGGATGTAAGGCGAGCGGACTATCGCA
AGTTACTGCATCAATTTGGGCGTTTAGGTGCTTCTTTGTGGAAAAAAAGTCACGGCATTGATGAACGTGAAGTGGTGACT
GAGCGCGAACGAAAATCTGTCGGTGTGGAGTACACCTTTAGCCAAAACATTTCGACGTTTCAGGAGTGTTGGCAAGTGAT
TGAACAGAAATTGTATCCGGAGCTAGATGCTCGTTTGAGTCGGGCTCACCCACAGCGAGGCATTATTAAACAAGGCATTA
AAGTGAAATTTGCTGATTTCCAACAGACAACCATTGAGCATGTTCACCCTGCATTAGAGCTCGACTACTTCCACGAGCTG
TTAGAGCAAGTGTTAACTCGCCAGCAAGGACGAGAAATTCGCTTACTTGGTTTAAGTGTCATGCTTAAGCCGGAATTGCA
GATGAAACAGCTATCGATGTTTCCGAGTGATGGATGGCAATAG

Upstream 100 bases:

>100_bases
ATCGCATCAAAAAGCTCGCTCCGGCGGGCTTTTTGTTTATCAGACTTTCCTTATCGATGGCTTATTATTATACTGTTTAT
GTATACAGTATTGGTGGGCT

Downstream 100 bases:

>100_bases
GCCGATGCCTCTCTTAAAACAGACATCATGGAGTGGGGTGATAAAGAGCGTTATCCTTTCGTCGCCTAATGCAAATCGTT
TGGTATAGTGTGTTTGTTAT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRM
SVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLN
KPNGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHEL
LEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ

Sequences:

>Translated_360_residues
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRM
SVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLN
KPNGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHEL
LEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
>Mature_360_residues
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSAMPTAQALKLCPQLHVVPGRM
SVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQGSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLN
KPNGLYVVTPDKVQEMVDSLPLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADFQQTTIEHVHPALELDYFHEL
LEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain

Homologues:

Organism=Homo sapiens, GI7706681, Length=214, Percent_Identity=33.6448598130841, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI84043967, Length=214, Percent_Identity=33.6448598130841, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI154350220, Length=302, Percent_Identity=28.8079470198675, Blast_Score=125, Evalue=8e-29,
Organism=Homo sapiens, GI7705344, Length=108, Percent_Identity=47.2222222222222, Blast_Score=112, Evalue=8e-25,
Organism=Homo sapiens, GI5729982, Length=123, Percent_Identity=37.3983739837398, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI1786425, Length=345, Percent_Identity=58.8405797101449, Blast_Score=403, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI193205700, Length=407, Percent_Identity=29.97542997543, Blast_Score=140, Evalue=8e-34,
Organism=Caenorhabditis elegans, GI17537959, Length=307, Percent_Identity=26.7100977198697, Blast_Score=113, Evalue=2e-25,
Organism=Caenorhabditis elegans, GI193205702, Length=348, Percent_Identity=25.2873563218391, Blast_Score=81, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI115534089, Length=125, Percent_Identity=38.4, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6324921, Length=204, Percent_Identity=29.4117647058824, Blast_Score=83, Evalue=6e-17,
Organism=Drosophila melanogaster, GI19923006, Length=325, Percent_Identity=30.1538461538462, Blast_Score=142, Evalue=3e-34,
Organism=Drosophila melanogaster, GI21355641, Length=283, Percent_Identity=29.6819787985866, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24644984, Length=283, Percent_Identity=29.6819787985866, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI24668444, Length=129, Percent_Identity=38.7596899224806, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DPO4_VIBC3 (A5F5Y1)

Other databases:

- EMBL:   CP000627
- EMBL:   CP001235
- ProteinModelPortal:   A5F5Y1
- SMR:   A5F5Y1
- STRING:   A5F5Y1
- GenomeReviews:   CP000627_GR
- GenomeReviews:   CP001235_GR
- KEGG:   vco:VC0395_A1876
- eggNOG:   COG0389
- HOGENOM:   HBG734504
- OMA:   HRIFRRY
- ProtClustDB:   PRK02406
- BioCyc:   VCHO345073:VC0395_A1876-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01113
- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880
- Gene3D:   G3DSA:3.30.1490.100
- PANTHER:   PTHR11076

Pfam domain/function: PF00817 IMS; SSF100879 DNA_pol_Y-fam_little_finger

EC number: =2.7.7.7

Molecular weight: Translated: 40891; Mature: 40891

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50173 UMUC

Important sites: ACT_SITE 108-108

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCCHHHCCHHHHHHHHHHC
MPTAQALKLCPQLHVVPGRMSVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQ
CCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
GSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLNKPNGLYVVTPDKVQEMVDSL
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHC
PLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
CHHHCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADF
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHCCCEEEECCH
QQTTIEHVHPALELDYFHELLEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCC
>Mature Secondary Structure
MQDRIRKIIHVDMDCFFAAVEMRDNPAYREIALAVGGHEKQRGVISTCNYQARKFGVRSA
CHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHCCCHHHCCHHHHHHHHHHC
MPTAQALKLCPQLHVVPGRMSVYKSVSQQIQTIFQRYTSLIEPLSLDEAYLDVSESTAYQ
CCHHHHHHHCCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCC
GSATLIAQAIRRDIWQELNLTASAGVAPIKFLAKVASDLNKPNGLYVVTPDKVQEMVDSL
CHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHC
PLEKIPGVGKVALEKLHQAGLYVGADVRRADYRKLLHQFGRLGASLWKKSHGIDEREVVT
CHHHCCCCHHHHHHHHHHCCCEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ERERKSVGVEYTFSQNISTFQECWQVIEQKLYPELDARLSRAHPQRGIIKQGIKVKFADF
HHHHHHCCEEEEECCCCHHHHHHHHHHHHHHCHHHHHHHHHCCCCCCHHHCCCEEEECCH
QQTTIEHVHPALELDYFHELLEQVLTRQQGREIRLLGLSVMLKPELQMKQLSMFPSDGWQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA