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The map label for this gene is iscR [H]

Identifier: 147673230

GI number: 147673230

Start: 291320

End: 291886

Strand: Direct

Name: iscR [H]

Synonym: VC0395_A0276

Alternate gene names: 147673230

Gene position: 291320-291886 (Clockwise)

Preceding gene: 147675237

Following gene: 147674054

Centisome position: 9.63

GC content: 48.68

Gene sequence:

>567_bases
ATGGAAAACTTCCAGCCACATAAACAGTGTGGATACGGTGTGATTATGAGACTGACATCTAAAGGAAGATATGCGGTAAC
AGCCATGTTAGATGTGGCTCTGCATTCGCAACAAAACCCAGTACCGTTGGCGGACATTTCTGAGCGCCAAGGCATTTCTC
TCTCGTACTTAGAGCAGCTTTTTTCTAAGTTACGTAAAGCGGGCTTAGTCGCCAGTGTGCGCGGTCCGGGCGGCGGTTAT
CGCTTAGGAATGGACTCATACGCCATTTCTATTGGTACTGTGATTGCCGCGGTTGATGAATCGGTCGATGCGACCAAATG
CAACGGGAAAGGGGATTGTCAGGGCGGGACTCGCTGTCTGACTCACACACTGTGGCGTGATCTCAGCTCACGCATTACGG
ATTTTCTTAACAACATCACGCTCGGTGAGCTGATGATGGATAACGAAGTTCTCGAAGTTTCAGATCGTCAAGATCTTCAT
CTTGCGGTCAGCCAAAGGGTTTCGCAAAACAACTCAAACACAGTCACCATTGGTGCTGCGCCTTTTGGTATTAATGTTCG
CTCATAG

Upstream 100 bases:

>100_bases
AGTACAAAAGTCAATCTCACGCAAAGAATAAGCTTATAAGTCTCAGGGTTAAATACCTGACTAAATTAGTCAAATAAATA
CTTGACCAAAAGAGTCAAGT

Downstream 100 bases:

>100_bases
CGGCAAGGTTTACACTGGAGTAGAAAATGAAACTGCCTATTTATCTAGATTATTCAGCGACATGCCCGGTTGATCCGCGC
GTAGCTGAAAAAATGGTTCA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 188; Mature: 188

Protein sequence:

>188_residues
MENFQPHKQCGYGVIMRLTSKGRYAVTAMLDVALHSQQNPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGY
RLGMDSYAISIGTVIAAVDESVDATKCNGKGDCQGGTRCLTHTLWRDLSSRITDFLNNITLGELMMDNEVLEVSDRQDLH
LAVSQRVSQNNSNTVTIGAAPFGINVRS

Sequences:

>Translated_188_residues
MENFQPHKQCGYGVIMRLTSKGRYAVTAMLDVALHSQQNPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGY
RLGMDSYAISIGTVIAAVDESVDATKCNGKGDCQGGTRCLTHTLWRDLSSRITDFLNNITLGELMMDNEVLEVSDRQDLH
LAVSQRVSQNNSNTVTIGAAPFGINVRS
>Mature_188_residues
MENFQPHKQCGYGVIMRLTSKGRYAVTAMLDVALHSQQNPVPLADISERQGISLSYLEQLFSKLRKAGLVASVRGPGGGY
RLGMDSYAISIGTVIAAVDESVDATKCNGKGDCQGGTRCLTHTLWRDLSSRITDFLNNITLGELMMDNEVLEVSDRQDLH
LAVSQRVSQNNSNTVTIGAAPFGINVRS

Specific function: Regulates the transcription of several operons and genes involved in the biogenesis of Fe-S clusters and Fe-S-containing proteins [H]

COG id: COG1959

COG function: function code K; Predicted transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH rrf2-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788880, Length=151, Percent_Identity=75.4966887417219, Blast_Score=209, Evalue=1e-55,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010242
- InterPro:   IPR000944
- InterPro:   IPR011991 [H]

Pfam domain/function: PF02082 Rrf2 [H]

EC number: NA

Molecular weight: Translated: 20390; Mature: 20390

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS01332 UPF0074

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENFQPHKQCGYGVIMRLTSKGRYAVTAMLDVALHSQQNPVPLADISERQGISLSYLEQL
CCCCCCCHHCCCEEEEEEECCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
FSKLRKAGLVASVRGPGGGYRLGMDSYAISIGTVIAAVDESVDATKCNGKGDCQGGTRCL
HHHHHHCCCEEEECCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHH
THTLWRDLSSRITDFLNNITLGELMMDNEVLEVSDRQDLHLAVSQRVSQNNSNTVTIGAA
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEECC
PFGINVRS
CCCEEECC
>Mature Secondary Structure
MENFQPHKQCGYGVIMRLTSKGRYAVTAMLDVALHSQQNPVPLADISERQGISLSYLEQL
CCCCCCCHHCCCEEEEEEECCCCEEHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHH
FSKLRKAGLVASVRGPGGGYRLGMDSYAISIGTVIAAVDESVDATKCNGKGDCQGGTRCL
HHHHHHCCCEEEECCCCCCEEECCHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCHHHH
THTLWRDLSSRITDFLNNITLGELMMDNEVLEVSDRQDLHLAVSQRVSQNNSNTVTIGAA
HHHHHHHHHHHHHHHHHCCCHHHHHCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEECC
PFGINVRS
CCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]