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The map label for this gene is coxS [H]

Identifier: 146343711

GI number: 146343711

Start: 7242659

End: 7243144

Strand: Direct

Name: coxS [H]

Synonym: BRADO6957

Alternate gene names: 146343711

Gene position: 7242659-7243144 (Clockwise)

Preceding gene: 146343710

Following gene: 146343712

Centisome position: 97.13

GC content: 64.61

Gene sequence:

>486_bases
GTGTCGACAGTCAAACTGACAGTGAACGGCAAGGCGGTCTCGGCGGAGGTCGAGGATCGCACCCTGCTGGTGCACCTGTT
GCGGGATCATCTCAATCTCACCGGCACCCATGTCGGCTGCGACACCAGCCAATGCGGCGCCTGCGTCGTGCACATTGACG
GCCGGGCCGTGAAATCCTGCACCGTGCTGGCCGGCCAGGCCGCCGGCGCCAACGTCACCACCATCGAAGGCATCGCCAAG
GGCGACGAGCTGCACCCGATGCAGGCCGCCTTCCGCGACAATCATGGCCTGCAATGCGGCTATTGCACGCCGGGCATGAT
CATGTCGGCGATCGATATTGTGCACCGCCACGGAGGTCACCTCGACGAGGCCACGGTGCGTGAAGAGCTGGAAGGCAACA
TCTGCCGCTGCACCGGCTATCACAACATCGTCAAGGCCGTGCTCGACGCCGCCGGCAGGATGAAGGTCGCCCAGGCCGCG
GAATAA

Upstream 100 bases:

>100_bases
GCAAGACGTCGCAATGACACCTCAGACGAAAATTCGAGTTGCAAAGTCCTGAGGGCGCTGTTTCTAATCAGAATAAGAAT
AATTCATCGGGAGGTTACTC

Downstream 100 bases:

>100_bases
AGCCGCCGAATCACGGCCGGCCGTCGGCTTTCGACGTCCTTCAATCAATACCGAGACCACGACCGCTGCGCGCGATGGCC
GCGGCGGGACAACAAACTCC

Product: putative carbon-monoxide dehydrogenase small subunit, coxS-like protein

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 161; Mature: 160

Protein sequence:

>161_residues
MSTVKLTVNGKAVSAEVEDRTLLVHLLRDHLNLTGTHVGCDTSQCGACVVHIDGRAVKSCTVLAGQAAGANVTTIEGIAK
GDELHPMQAAFRDNHGLQCGYCTPGMIMSAIDIVHRHGGHLDEATVREELEGNICRCTGYHNIVKAVLDAAGRMKVAQAA
E

Sequences:

>Translated_161_residues
MSTVKLTVNGKAVSAEVEDRTLLVHLLRDHLNLTGTHVGCDTSQCGACVVHIDGRAVKSCTVLAGQAAGANVTTIEGIAK
GDELHPMQAAFRDNHGLQCGYCTPGMIMSAIDIVHRHGGHLDEATVREELEGNICRCTGYHNIVKAVLDAAGRMKVAQAA
E
>Mature_160_residues
STVKLTVNGKAVSAEVEDRTLLVHLLRDHLNLTGTHVGCDTSQCGACVVHIDGRAVKSCTVLAGQAAGANVTTIEGIAKG
DELHPMQAAFRDNHGLQCGYCTPGMIMSAIDIVHRHGGHLDEATVREELEGNICRCTGYHNIVKAVLDAAGRMKVAQAAE

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG2080

COG function: function code C; Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI71773480, Length=158, Percent_Identity=36.7088607594937, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI91823271, Length=154, Percent_Identity=35.0649350649351, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786480, Length=168, Percent_Identity=45.8333333333333, Blast_Score=141, Evalue=2e-35,
Organism=Escherichia coli, GI1789232, Length=148, Percent_Identity=40.5405405405405, Blast_Score=112, Evalue=2e-26,
Organism=Caenorhabditis elegans, GI17540638, Length=168, Percent_Identity=37.5, Blast_Score=106, Evalue=6e-24,
Organism=Caenorhabditis elegans, GI17539860, Length=153, Percent_Identity=34.640522875817, Blast_Score=100, Evalue=6e-22,
Organism=Caenorhabditis elegans, GI32566215, Length=158, Percent_Identity=34.1772151898734, Blast_Score=99, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24647197, Length=175, Percent_Identity=33.7142857142857, Blast_Score=101, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24647195, Length=175, Percent_Identity=33.7142857142857, Blast_Score=100, Evalue=4e-22,
Organism=Drosophila melanogaster, GI24647201, Length=157, Percent_Identity=35.6687898089172, Blast_Score=98, Evalue=3e-21,
Organism=Drosophila melanogaster, GI17737937, Length=156, Percent_Identity=37.1794871794872, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647199, Length=167, Percent_Identity=32.3353293413174, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24647193, Length=172, Percent_Identity=33.7209302325581, Blast_Score=90, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 17012; Mature: 16880

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
8.1 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
7.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVKLTVNGKAVSAEVEDRTLLVHLLRDHLNLTGTHVGCDTSQCGACVVHIDGRAVKSC
CCEEEEEECCEEEEEECCHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCCCEE
TVLAGQAAGANVTTIEGIAKGDELHPMQAAFRDNHGLQCGYCTPGMIMSAIDIVHRHGGH
EEEECCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCC
LDEATVREELEGNICRCTGYHNIVKAVLDAAGRMKVAQAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCHHCCCC
>Mature Secondary Structure 
STVKLTVNGKAVSAEVEDRTLLVHLLRDHLNLTGTHVGCDTSQCGACVVHIDGRAVKSC
CEEEEEECCEEEEEECCHHHHHHHHHHHHCCCCCEECCCCCCCCCEEEEEECCCCCCEE
TVLAGQAAGANVTTIEGIAKGDELHPMQAAFRDNHGLQCGYCTPGMIMSAIDIVHRHGGH
EEEECCCCCCCEEEECCCCCCCCCCHHHHHHCCCCCCEECCCCHHHHHHHHHHHHHCCCC
LDEATVREELEGNICRCTGYHNIVKAVLDAAGRMKVAQAAE
CCHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7721710; 2818128; 10430865; 12475995 [H]