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The map label for this gene is ddpA [H]

Identifier: 146343585

GI number: 146343585

Start: 7081316

End: 7082941

Strand: Reverse

Name: ddpA [H]

Synonym: BRADO6823

Alternate gene names: 146343585

Gene position: 7082941-7081316 (Counterclockwise)

Preceding gene: 146343586

Following gene: 146343584

Centisome position: 94.99

GC content: 61.87

Gene sequence:

>1626_bases
TTGATGAAGCGTCGCGATTTTCTGAAGTCCGTGTCCGGTTTGGCGGCAGGCGCCGCGCTGCCGATGGCGCCGGCGGTGAT
GTCCTCCGCCAAGGCCGACGCGCGGTCCGAGACGCTGCTCATCGTGTCCGAGGGCGGCCCCAACAATCTCGACATCCATG
GCGTCGGCACCAACGTGCCGGGCTATGAGGTGTCGTGGAATTGCTACGACCGTCTGATCAGCCACGAGATGAAGAGTGGC
CCCGGCGGCATCCCGTATTACGACCGCGACAAGTTCAAGCCCGAGCTTGCCGAGGACATGACAATCGGCGACATGTCGGC
GACCTTCAAGCTGCGCAAGAACGCCAAATTCCACGATGGCACGCCGGTCACCGCCAAGGACGTCAAATGGTCGCTCGACC
GCGCGGTCAGCGTCGGTGGCTTCCCGACCTTTCAGATGAGCGCGGGCTCGCTGACTAAGCCGGAGCAGTTCGTCATCGTC
GACGACTACACCGTGCGCGTCGACTTTCTGAAGAAGGACCGTCTGACGATTCCGGATCTCGCCGTCATCGTGCCCTGTGT
GGTCAATTCCGAGCTGGTAAAGAAGAACGCCACCGACAAGGATCCGTGGGGTCTCGAATACACCAAGCAGCAGACGGCAG
GCTCCGGTGCCTACAAGGTGACGAAGTGGACCGCCGGCACCGAGGTCGTCATGGAACGCAACGACGACTGGGTGTGCGGG
CCGCTGCCGAAGATCAGGCGCGTGATCTGGCGCATGGTGCCGCAGGCCGGCAACCGCCGCGCGCTGCTGGAGCGCGGCGA
TGCCGACATTTCTTATGAGCTGCCGAACAAGGACTTCCAGGAGATGAAGTCGAACGGCAAGCACACCGTGATTTCGCTGC
CGATCTCGAACGGCATCCAGTACATCGGCATGAACGTGACCAAGCCGCCATTCGATAATCCCAAGGTGCGCCAGGCGCTC
GCCTATGCCATGCCCTATCAGAAGATCATCGACGCCGTAATGTTCGGCCTCGCCAATCCGATGTTCGGGGCACCGGCCGA
CAAGGCGACCGAGGTGGCCTGGCCGCAGCCGACGAAGTATGTCACCGACATGGAGAAGGCGAAGGCGCTGCTGGCCGAGG
CCGGCTACGCCAACGGGTTCGAGACGACGATCTCGTTCGATCTGAACTTCGCGCAGGTCAACGAGCCGCTCTGCGTGCTG
GTGCAGGAGAGCCTCGCGCAGCTCGGGATCAAGACCACGATCAACAAGGTGCCCGGCGCCAACTGGCGCACCGAGCTGAA
CAAGAAGGAGATGCCGCTCTTCACCAACATCTTCTCAGGCTGGCTCGATTACCCCGAATACTTCTTCTACTGGTGCTATC
ACGGCAACAATTCCGTGTTCAACACGATGAGCTACAAGTCGCCGGAGATGGACAAGCTCATCAACGGCGCCCGCGATGCT
GCCTCGACGGGCGACAAGGCGGCCTACGATGCCGACGTCAAGGGCTTCGTCGACCTCGCCTTCGCCGACGTGCCGCGCAT
TCCGCTGTATCAGCCGTTCGTCAACGTCGCGATGCAGAAGAACATCTCCGGCTATCAGTACTGGTTCCACCGCCGCCTCG
ACTATCGCGCGCTGGTGAAGGGGTGA

Upstream 100 bases:

>100_bases
TCCTAAGCAAAGCCAAATTTAATCAAAGACTTGGTTCGCTGCTGCGCTTGGCACGAAGATTGCGATCTCTGCTCTCGCCG
GTCGTAGTCCGTGGGAGCAC

Downstream 100 bases:

>100_bases
GCGGCGTGGCTGGGGTGAGTGAGGCGGCCCGATCTCTTTCATTCCCTCCACCCTTGTGGGGGAGGGGCAGGGAGGGGGGT
AGCCACAGGCACCACCTTCT

Product: peptide/oligopeptide/nickel ABC transporter substrate-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 541; Mature: 541

Protein sequence:

>541_residues
MMKRRDFLKSVSGLAAGAALPMAPAVMSSAKADARSETLLIVSEGGPNNLDIHGVGTNVPGYEVSWNCYDRLISHEMKSG
PGGIPYYDRDKFKPELAEDMTIGDMSATFKLRKNAKFHDGTPVTAKDVKWSLDRAVSVGGFPTFQMSAGSLTKPEQFVIV
DDYTVRVDFLKKDRLTIPDLAVIVPCVVNSELVKKNATDKDPWGLEYTKQQTAGSGAYKVTKWTAGTEVVMERNDDWVCG
PLPKIRRVIWRMVPQAGNRRALLERGDADISYELPNKDFQEMKSNGKHTVISLPISNGIQYIGMNVTKPPFDNPKVRQAL
AYAMPYQKIIDAVMFGLANPMFGAPADKATEVAWPQPTKYVTDMEKAKALLAEAGYANGFETTISFDLNFAQVNEPLCVL
VQESLAQLGIKTTINKVPGANWRTELNKKEMPLFTNIFSGWLDYPEYFFYWCYHGNNSVFNTMSYKSPEMDKLINGARDA
ASTGDKAAYDADVKGFVDLAFADVPRIPLYQPFVNVAMQKNISGYQYWFHRRLDYRALVKG

Sequences:

>Translated_541_residues
MMKRRDFLKSVSGLAAGAALPMAPAVMSSAKADARSETLLIVSEGGPNNLDIHGVGTNVPGYEVSWNCYDRLISHEMKSG
PGGIPYYDRDKFKPELAEDMTIGDMSATFKLRKNAKFHDGTPVTAKDVKWSLDRAVSVGGFPTFQMSAGSLTKPEQFVIV
DDYTVRVDFLKKDRLTIPDLAVIVPCVVNSELVKKNATDKDPWGLEYTKQQTAGSGAYKVTKWTAGTEVVMERNDDWVCG
PLPKIRRVIWRMVPQAGNRRALLERGDADISYELPNKDFQEMKSNGKHTVISLPISNGIQYIGMNVTKPPFDNPKVRQAL
AYAMPYQKIIDAVMFGLANPMFGAPADKATEVAWPQPTKYVTDMEKAKALLAEAGYANGFETTISFDLNFAQVNEPLCVL
VQESLAQLGIKTTINKVPGANWRTELNKKEMPLFTNIFSGWLDYPEYFFYWCYHGNNSVFNTMSYKSPEMDKLINGARDA
ASTGDKAAYDADVKGFVDLAFADVPRIPLYQPFVNVAMQKNISGYQYWFHRRLDYRALVKG
>Mature_541_residues
MMKRRDFLKSVSGLAAGAALPMAPAVMSSAKADARSETLLIVSEGGPNNLDIHGVGTNVPGYEVSWNCYDRLISHEMKSG
PGGIPYYDRDKFKPELAEDMTIGDMSATFKLRKNAKFHDGTPVTAKDVKWSLDRAVSVGGFPTFQMSAGSLTKPEQFVIV
DDYTVRVDFLKKDRLTIPDLAVIVPCVVNSELVKKNATDKDPWGLEYTKQQTAGSGAYKVTKWTAGTEVVMERNDDWVCG
PLPKIRRVIWRMVPQAGNRRALLERGDADISYELPNKDFQEMKSNGKHTVISLPISNGIQYIGMNVTKPPFDNPKVRQAL
AYAMPYQKIIDAVMFGLANPMFGAPADKATEVAWPQPTKYVTDMEKAKALLAEAGYANGFETTISFDLNFAQVNEPLCVL
VQESLAQLGIKTTINKVPGANWRTELNKKEMPLFTNIFSGWLDYPEYFFYWCYHGNNSVFNTMSYKSPEMDKLINGARDA
ASTGDKAAYDADVKGFVDLAFADVPRIPLYQPFVNVAMQKNISGYQYWFHRRLDYRALVKG

Specific function: Part of the ABC transporter complex ddpABCDF, which is probably involved in D,D-dipeptide transport [H]

COG id: COG0747

COG function: function code E; ABC-type dipeptide transport system, periplasmic component

Gene ontology:

Cell location: Periplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1787762, Length=535, Percent_Identity=26.1682242990654, Blast_Score=144, Evalue=2e-35,
Organism=Escherichia coli, GI1787052, Length=516, Percent_Identity=27.3255813953488, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI1789966, Length=471, Percent_Identity=26.7515923566879, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI1787495, Length=516, Percent_Identity=24.6124031007752, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1787551, Length=349, Percent_Identity=24.9283667621776, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081878, Length=427, Percent_Identity=23.8875878220141, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1789887, Length=171, Percent_Identity=29.8245614035088, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 60338; Mature: 60338

Theoretical pI: Translated: 8.37; Mature: 8.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKRRDFLKSVSGLAAGAALPMAPAVMSSAKADARSETLLIVSEGGPNNLDIHGVGTNVP
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCC
GYEVSWNCYDRLISHEMKSGPGGIPYYDRDKFKPELAEDMTIGDMSATFKLRKNAKFHDG
CEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCEECCCCEEEEEECCCCCCCC
TPVTAKDVKWSLDRAVSVGGFPTFQMSAGSLTKPEQFVIVDDYTVRVDFLKKDRLTIPDL
CCCCHHHHHHHHHHHEECCCCCEEEECCCCCCCCCEEEEEECEEEEEEEEECCCCCCCHH
AVIVPCVVNSELVKKNATDKDPWGLEYTKQQTAGSGAYKVTKWTAGTEVVMERNDDWVCG
HHHHHHHHCHHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCCCEEEC
PLPKIRRVIWRMVPQAGNRRALLERGDADISYELPNKDFQEMKSNGKHTVISLPISNGIQ
CHHHHHHHHHHHCCCCCCCEEHHCCCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCE
YIGMNVTKPPFDNPKVRQALAYAMPYQKIIDAVMFGLANPMFGAPADKATEVAWPQPTKY
EEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
VTDMEKAKALLAEAGYANGFETTISFDLNFAQVNEPLCVLVQESLAQLGIKTTINKVPGA
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCC
NWRTELNKKEMPLFTNIFSGWLDYPEYFFYWCYHGNNSVFNTMSYKSPEMDKLINGARDA
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCCCCCHHHHHCCHHHH
ASTGDKAAYDADVKGFVDLAFADVPRIPLYQPFVNVAMQKNISGYQYWFHRRLDYRALVK
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCC
G
C
>Mature Secondary Structure
MMKRRDFLKSVSGLAAGAALPMAPAVMSSAKADARSETLLIVSEGGPNNLDIHGVGTNVP
CCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCCEEEEEECCCCC
GYEVSWNCYDRLISHEMKSGPGGIPYYDRDKFKPELAEDMTIGDMSATFKLRKNAKFHDG
CEEEEHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCEECCCCEEEEEECCCCCCCC
TPVTAKDVKWSLDRAVSVGGFPTFQMSAGSLTKPEQFVIVDDYTVRVDFLKKDRLTIPDL
CCCCHHHHHHHHHHHEECCCCCEEEECCCCCCCCCEEEEEECEEEEEEEEECCCCCCCHH
AVIVPCVVNSELVKKNATDKDPWGLEYTKQQTAGSGAYKVTKWTAGTEVVMERNDDWVCG
HHHHHHHHCHHHHHCCCCCCCCCCCCCCHHHCCCCCCEEEEEECCCCEEEEECCCCEEEC
PLPKIRRVIWRMVPQAGNRRALLERGDADISYELPNKDFQEMKSNGKHTVISLPISNGIQ
CHHHHHHHHHHHCCCCCCCEEHHCCCCCCEEEECCCCHHHHHHCCCCEEEEEEECCCCCE
YIGMNVTKPPFDNPKVRQALAYAMPYQKIIDAVMFGLANPMFGAPADKATEVAWPQPTKY
EEECCCCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHH
VTDMEKAKALLAEAGYANGFETTISFDLNFAQVNEPLCVLVQESLAQLGIKTTINKVPGA
HHHHHHHHHHHHHCCCCCCCCEEEEEEEEHHHHCCCHHHHHHHHHHHCCHHHHHHCCCCC
NWRTELNKKEMPLFTNIFSGWLDYPEYFFYWCYHGNNSVFNTMSYKSPEMDKLINGARDA
CCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEECCCCEEECCCCCCCCHHHHHCCHHHH
ASTGDKAAYDADVKGFVDLAFADVPRIPLYQPFVNVAMQKNISGYQYWFHRRLDYRALVK
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCHHHHCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9751644 [H]