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The map label for this gene is speB2 [H]

Identifier: 146343558

GI number: 146343558

Start: 7054487

End: 7055692

Strand: Reverse

Name: speB2 [H]

Synonym: BRADO6795

Alternate gene names: 146343558

Gene position: 7055692-7054487 (Counterclockwise)

Preceding gene: 146343559

Following gene: 146343557

Centisome position: 94.62

GC content: 66.5

Gene sequence:

>1206_bases
ATGTCATTCCCAGCCATGCGGCGCAGCCGCCGTGCCGGATTGCAGCCGCAGCGCTCGCGCCTGCGCCGGCATCATCCGGA
CTTTGACAAGATGGCGACGCAAGGCTGGCAGGCGCTGGAGGCCGAGGGCAAGCTGCCGAGCAACGGCTGGCGCAAGGAGC
GGCAATGGGCGCTCGACATGGGCCTGCCCGGCTCGGACAGCCTGACCGATCGCGACATCCCGACCTTCGCGCGCGGTGAG
CTGCCGCATTTCGCTGGGATCAACACCTTCATGAAGGCGCCCTATGTCGAGAACGTCCGCGACGTCGGCAAATACGACGC
CGCCGTGATCGGCATCCCGTTCGATTCCGGCACCACCTATCGTCCCGGCACGCGCTTCGGGCCGCAGGGCATCCGCCGCA
TCTCCGCGCTCTACACGCCCTACAATTACGAGCTCGGCGTCGACCTGCGCGAGCAGATGACTTTGTGCGATGCCGGTGAC
GTCTTCACCATCCCGGCGAACCTCGAAAAGAGCTTCGACCAGATCAGCCGCGGCGTCGCGCATGTGTTCTCGTCTGGCGC
GCTGCCGATCATGCTCGGCGGCGACCACTCGATCGGCTTCCCCTGCGTGCGCGGCATCGCGCAGTGCACCGACAAGAGGA
TCGGCATCATCCATTTCGACCGCCACATCGACATCCAGGAGAAGGATCTCGACGAGCGCATGCACACCACGCCCTGGTAC
TGGGCAACCAATCTGCCGAACGTCTCGCCGACCAATCTGGTCCAGCTCGGCATCGGCGGCTGGCAGGTGCCGCGCGAGGG
CGTCGAGGTCGCGCGCAAGCGCAACACCAACGTGCTGACCATCGCCGACATCGAGAAGATCGGCCTGGAGAAGACCGCCG
AGATCGCGCTGGAGCTGGCCTGGAAGGATGCCGACGCCGTCTACATCTCGTTCGACGTCGATTCCATCGATTGCGGCTTC
GTGCCCGGCACCGGCTGGCCGGAGCCCGGCGGCTTCCTGCCGCGCGAGGCGCTGAAGCTGCTCGGCCTCGTCGCCGCCGA
GGGCCTCTGCGGCCTCGAAGTGGTCGAGGTCTCGCCGCCCTACGATACGTCCGACATCACCGCGCTGATCGGCGTGCGCG
TCGTCGTCGAGGCGCTGGGCTCGATGGTCGCCCACGGCAAGCTCGGCAGCCACAAGCACATCATCAACAAGCCGGTCAGC
TTCTGA

Upstream 100 bases:

>100_bases
CCTCGATCTCACCCGCGACAGTCCTGTGCCCGTGCTCGGCTTCATCCGCGCCAGCGTGCAGGCGGCGCAATAACACTCAG
AAGAAACGAAGGAGAACTCC

Downstream 100 bases:

>100_bases
GGTCCGCGATGCGCCATCATCACCACTATCACGGCCATCATCATGATCATGGTCATTCTCACGATCATGATCATCACCAT
GATCACGATCATCCGCCGCA

Product: putative agmatine ureohydrolase

Products: NA

Alternate protein names: Agmatine ureohydrolase 2; AUH 2 [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSFPAMRRSRRAGLQPQRSRLRRHHPDFDKMATQGWQALEAEGKLPSNGWRKERQWALDMGLPGSDSLTDRDIPTFARGE
LPHFAGINTFMKAPYVENVRDVGKYDAAVIGIPFDSGTTYRPGTRFGPQGIRRISALYTPYNYELGVDLREQMTLCDAGD
VFTIPANLEKSFDQISRGVAHVFSSGALPIMLGGDHSIGFPCVRGIAQCTDKRIGIIHFDRHIDIQEKDLDERMHTTPWY
WATNLPNVSPTNLVQLGIGGWQVPREGVEVARKRNTNVLTIADIEKIGLEKTAEIALELAWKDADAVYISFDVDSIDCGF
VPGTGWPEPGGFLPREALKLLGLVAAEGLCGLEVVEVSPPYDTSDITALIGVRVVVEALGSMVAHGKLGSHKHIINKPVS
F

Sequences:

>Translated_401_residues
MSFPAMRRSRRAGLQPQRSRLRRHHPDFDKMATQGWQALEAEGKLPSNGWRKERQWALDMGLPGSDSLTDRDIPTFARGE
LPHFAGINTFMKAPYVENVRDVGKYDAAVIGIPFDSGTTYRPGTRFGPQGIRRISALYTPYNYELGVDLREQMTLCDAGD
VFTIPANLEKSFDQISRGVAHVFSSGALPIMLGGDHSIGFPCVRGIAQCTDKRIGIIHFDRHIDIQEKDLDERMHTTPWY
WATNLPNVSPTNLVQLGIGGWQVPREGVEVARKRNTNVLTIADIEKIGLEKTAEIALELAWKDADAVYISFDVDSIDCGF
VPGTGWPEPGGFLPREALKLLGLVAAEGLCGLEVVEVSPPYDTSDITALIGVRVVVEALGSMVAHGKLGSHKHIINKPVS
F
>Mature_400_residues
SFPAMRRSRRAGLQPQRSRLRRHHPDFDKMATQGWQALEAEGKLPSNGWRKERQWALDMGLPGSDSLTDRDIPTFARGEL
PHFAGINTFMKAPYVENVRDVGKYDAAVIGIPFDSGTTYRPGTRFGPQGIRRISALYTPYNYELGVDLREQMTLCDAGDV
FTIPANLEKSFDQISRGVAHVFSSGALPIMLGGDHSIGFPCVRGIAQCTDKRIGIIHFDRHIDIQEKDLDERMHTTPWYW
ATNLPNVSPTNLVQLGIGGWQVPREGVEVARKRNTNVLTIADIEKIGLEKTAEIALELAWKDADAVYISFDVDSIDCGFV
PGTGWPEPGGFLPREALKLLGLVAAEGLCGLEVVEVSPPYDTSDITALIGVRVVVEALGSMVAHGKLGSHKHIINKPVSF

Specific function: Catalyzes The Formation Of Putrescine From Agmatine. [C]

COG id: COG0010

COG function: function code E; Arginase/agmatinase/formimionoglutamate hydrolase, arginase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arginase family. Agmatinase subfamily [H]

Homologues:

Organism=Homo sapiens, GI37537722, Length=299, Percent_Identity=31.7725752508361, Blast_Score=158, Evalue=8e-39,
Organism=Homo sapiens, GI10947139, Length=319, Percent_Identity=25.705329153605, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI4502215, Length=326, Percent_Identity=24.2331288343558, Blast_Score=84, Evalue=2e-16,
Organism=Escherichia coli, GI1789306, Length=267, Percent_Identity=29.2134831460674, Blast_Score=117, Evalue=9e-28,
Organism=Saccharomyces cerevisiae, GI6325146, Length=215, Percent_Identity=26.046511627907, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006035
- InterPro:   IPR020855 [H]

Pfam domain/function: PF00491 Arginase [H]

EC number: =3.5.3.11 [H]

Molecular weight: Translated: 44229; Mature: 44098

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPAMRRSRRAGLQPQRSRLRRHHPDFDKMATQGWQALEAEGKLPSNGWRKERQWALDM
CCCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHCCHHHHCCCCCCCCCCCHHHHEEEEC
GLPGSDSLTDRDIPTFARGELPHFAGINTFMKAPYVENVRDVGKYDAAVIGIPFDSGTTY
CCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHCCHHHHHHHHCCCCEEEEEEECCCCCCC
RPGTRFGPQGIRRISALYTPYNYELGVDLREQMTLCDAGDVFTIPANLEKSFDQISRGVA
CCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHEECCCCEEEECCHHHHHHHHHHHHHH
HVFSSGALPIMLGGDHSIGFPCVRGIAQCTDKRIGIIHFDRHIDIQEKDLDERMHTTPWY
HHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCE
WATNLPNVSPTNLVQLGIGGWQVPREGVEVARKRNTNVLTIADIEKIGLEKTAEIALELA
EECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEECHHHHCCHHHHHEEEEEE
WKDADAVYISFDVDSIDCGFVPGTGWPEPGGFLPREALKLLGLVAAEGLCGLEVVEVSPP
ECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
YDTSDITALIGVRVVVEALGSMVAHGKLGSHKHIINKPVSF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCC
>Mature Secondary Structure 
SFPAMRRSRRAGLQPQRSRLRRHHPDFDKMATQGWQALEAEGKLPSNGWRKERQWALDM
CCHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHCCHHHHCCCCCCCCCCCHHHHEEEEC
GLPGSDSLTDRDIPTFARGELPHFAGINTFMKAPYVENVRDVGKYDAAVIGIPFDSGTTY
CCCCCCCCCCCCCCCCCCCCCCCHHCCHHHHHCCHHHHHHHHCCCCEEEEEEECCCCCCC
RPGTRFGPQGIRRISALYTPYNYELGVDLREQMTLCDAGDVFTIPANLEKSFDQISRGVA
CCCCCCCHHHHHHHHHHCCCCCEEECCCHHHHHHEECCCCEEEECCHHHHHHHHHHHHHH
HVFSSGALPIMLGGDHSIGFPCVRGIAQCTDKRIGIIHFDRHIDIQEKDLDERMHTTPWY
HHHCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHCCCCCE
WATNLPNVSPTNLVQLGIGGWQVPREGVEVARKRNTNVLTIADIEKIGLEKTAEIALELA
EECCCCCCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEEEECHHHHCCHHHHHEEEEEE
WKDADAVYISFDVDSIDCGFVPGTGWPEPGGFLPREALKLLGLVAAEGLCGLEVVEVSPP
ECCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCC
YDTSDITALIGVRVVVEALGSMVAHGKLGSHKHIINKPVSF
CCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]