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The map label for this gene is matE1 [H]

Identifier: 146343509

GI number: 146343509

Start: 7002229

End: 7003512

Strand: Direct

Name: matE1 [H]

Synonym: BRADO6741

Alternate gene names: 146343509

Gene position: 7002229-7003512 (Clockwise)

Preceding gene: 146343508

Following gene: 146343512

Centisome position: 93.91

GC content: 68.54

Gene sequence:

>1284_bases
GTGTTTCACATCGCCGGCCCCGCGATGATCGCCAACCTGACGACGCCGCTGATCGGCATCGTGTCGACCACCGCGATCGG
CCGGCTCGGCGAGGCCGCGATGCTCGGCGGCGTCGCGATGGCCTCGGTGATCTTCGACTGCCTGTTCTGGCTGTTCGCCT
TCCTCCGCGCCAGCACGCTCGCCTTCACCGCGCAATCGCTCGGCGCCGGCGAGAGCGACGAGATCCGGATGGTGCTGATC
CGCGGCCTGGCATTGGCCGCGCTGATCGGCGTCGCCTTGATCGCGCTGCAGCTGCCGATCGCCGCAATCATCTTCGAGCT
GATGGGCGGCAGCGACGCCGTTCTCGGCGCCGCGCGGACCTATTTCAAGGTGCGGATCTGGTCGGCGCCGTTCGCCCTCG
CCAACTACGTGCTGCTCGGCTGGCTGGTCGGGCTGGCCCGGGCCAGGCTGGCGCTTGCGGTCCAGGTCGCGATCAACCTC
ATCAACATGGCGGCGACCATCCTCCTGGTGCAGGTGCTGGAGAGGGGCATTGCCGGCGCGGCGATCGCCGCGCTGGTAGC
GGAGACGGTCGGCGTCGCCATCGGTCTGCTGCTGGCGCGCCGGCTGGTGACGACGACGCACGGCCTGTCACTGCCGCTGC
TGTTCGATCGCGCTAAGCTGATGCACATGATGGCCATCAATCGCGACATCATGATCCGCACCGCGGCGATGATCGTGGCC
TTCCTGTTCTTCACCGCGCAGGGCGCGCGCGCCGGCGACACGACGCTCGCCGCCAACGCGGTGCTGAACAATTTCCTGCT
GGTCGCCGCGTTCTTCCTCGACGGGCTCGCCAACGCCGCCGAGCAGCTCTGCGGCTATGCGTTCGGCGCCCGCAACCGCG
ACGCCTTCGCCGGCGCCACCCGGCTGGTGCTGGGCTGGGGCTTCGGCTTCGCGCTGGTGGTGGCCGTCATCTTCGTGCTG
TTCGGACCTGAGCTGATCGACGTCATGACGGCGAGCCCTGCCGTGCGCAGCGCCGGGCGCGACTACCTGCCATACGTGGT
GGCCTCGCCGCTGGTGTCGGTCTTCGCCTTCGCGTTCGACGGCGTCTATATCGGCGCCACCTGGGCCCGCGACATGCGCA
ACCTGATGATCGCGGCACTGATCGTGTTCCTCGGTGTATGGCTCGCGCTGCGCGGCTTCGGCAACACCGGATTGTGGGTC
GCTTTGCTCAGCTTTTACGCGGCCCGCGGCGGCTTCCAGGCCGCCCGCTATCCGGCGCTGCTGAGGATGTCGTTCGCCAA
GTAG

Upstream 100 bases:

>100_bases
AAGACGGATAAGCATGGGCCGTGCCGGACTTTCGGCACGGCCAGCGAGACGTCCGTTGCATTCACCCGCCCCCCACCGAT
CGACCGTGACCAGCGCGCAG

Downstream 100 bases:

>100_bases
AACAGAGTTGATGGCGGCGGCACACATCGCAACGCAACTCAAAGCTGGCTTAAGGATGAGCGCGGTGCTCGTGAATGCGC
CCTCTCCCCTTGCGGGAGAG

Product: cation efflux pump, DNA-damage-inducible protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 427; Mature: 427

Protein sequence:

>427_residues
MFHIAGPAMIANLTTPLIGIVSTTAIGRLGEAAMLGGVAMASVIFDCLFWLFAFLRASTLAFTAQSLGAGESDEIRMVLI
RGLALAALIGVALIALQLPIAAIIFELMGGSDAVLGAARTYFKVRIWSAPFALANYVLLGWLVGLARARLALAVQVAINL
INMAATILLVQVLERGIAGAAIAALVAETVGVAIGLLLARRLVTTTHGLSLPLLFDRAKLMHMMAINRDIMIRTAAMIVA
FLFFTAQGARAGDTTLAANAVLNNFLLVAAFFLDGLANAAEQLCGYAFGARNRDAFAGATRLVLGWGFGFALVVAVIFVL
FGPELIDVMTASPAVRSAGRDYLPYVVASPLVSVFAFAFDGVYIGATWARDMRNLMIAALIVFLGVWLALRGFGNTGLWV
ALLSFYAARGGFQAARYPALLRMSFAK

Sequences:

>Translated_427_residues
MFHIAGPAMIANLTTPLIGIVSTTAIGRLGEAAMLGGVAMASVIFDCLFWLFAFLRASTLAFTAQSLGAGESDEIRMVLI
RGLALAALIGVALIALQLPIAAIIFELMGGSDAVLGAARTYFKVRIWSAPFALANYVLLGWLVGLARARLALAVQVAINL
INMAATILLVQVLERGIAGAAIAALVAETVGVAIGLLLARRLVTTTHGLSLPLLFDRAKLMHMMAINRDIMIRTAAMIVA
FLFFTAQGARAGDTTLAANAVLNNFLLVAAFFLDGLANAAEQLCGYAFGARNRDAFAGATRLVLGWGFGFALVVAVIFVL
FGPELIDVMTASPAVRSAGRDYLPYVVASPLVSVFAFAFDGVYIGATWARDMRNLMIAALIVFLGVWLALRGFGNTGLWV
ALLSFYAARGGFQAARYPALLRMSFAK
>Mature_427_residues
MFHIAGPAMIANLTTPLIGIVSTTAIGRLGEAAMLGGVAMASVIFDCLFWLFAFLRASTLAFTAQSLGAGESDEIRMVLI
RGLALAALIGVALIALQLPIAAIIFELMGGSDAVLGAARTYFKVRIWSAPFALANYVLLGWLVGLARARLALAVQVAINL
INMAATILLVQVLERGIAGAAIAALVAETVGVAIGLLLARRLVTTTHGLSLPLLFDRAKLMHMMAINRDIMIRTAAMIVA
FLFFTAQGARAGDTTLAANAVLNNFLLVAAFFLDGLANAAEQLCGYAFGARNRDAFAGATRLVLGWGFGFALVVAVIFVL
FGPELIDVMTASPAVRSAGRDYLPYVVASPLVSVFAFAFDGVYIGATWARDMRNLMIAALIVFLGVWLALRGFGNTGLWV
ALLSFYAARGGFQAARYPALLRMSFAK

Specific function: Unknown

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI1790477, Length=412, Percent_Identity=37.378640776699, Blast_Score=196, Evalue=2e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 45144; Mature: 45144

Theoretical pI: Translated: 10.34; Mature: 10.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHIAGPAMIANLTTPLIGIVSTTAIGRLGEAAMLGGVAMASVIFDCLFWLFAFLRASTL
CCEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFTAQSLGAGESDEIRMVLIRGLALAALIGVALIALQLPIAAIIFELMGGSDAVLGAART
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
YFKVRIWSAPFALANYVLLGWLVGLARARLALAVQVAINLINMAATILLVQVLERGIAGA
HEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIAALVAETVGVAIGLLLARRLVTTTHGLSLPLLFDRAKLMHMMAINRDIMIRTAAMIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FLFFTAQGARAGDTTLAANAVLNNFLLVAAFFLDGLANAAEQLCGYAFGARNRDAFAGAT
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RLVLGWGFGFALVVAVIFVLFGPELIDVMTASPAVRSAGRDYLPYVVASPLVSVFAFAFD
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GVYIGATWARDMRNLMIAALIVFLGVWLALRGFGNTGLWVALLSFYAARGGFQAARYPAL
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LRMSFAK
HHHHCCC
>Mature Secondary Structure
MFHIAGPAMIANLTTPLIGIVSTTAIGRLGEAAMLGGVAMASVIFDCLFWLFAFLRASTL
CCEECCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AFTAQSLGAGESDEIRMVLIRGLALAALIGVALIALQLPIAAIIFELMGGSDAVLGAART
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHH
YFKVRIWSAPFALANYVLLGWLVGLARARLALAVQVAINLINMAATILLVQVLERGIAGA
HEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
AIAALVAETVGVAIGLLLARRLVTTTHGLSLPLLFDRAKLMHMMAINRDIMIRTAAMIVA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
FLFFTAQGARAGDTTLAANAVLNNFLLVAAFFLDGLANAAEQLCGYAFGARNRDAFAGAT
HHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
RLVLGWGFGFALVVAVIFVLFGPELIDVMTASPAVRSAGRDYLPYVVASPLVSVFAFAFD
HHHHHHHHHHHHHHHHHHHHHCHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHHHHC
GVYIGATWARDMRNLMIAALIVFLGVWLALRGFGNTGLWVALLSFYAARGGFQAARYPAL
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCHHHHHHH
LRMSFAK
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]