Click here to switch to the map view.

The map label for this gene is pqqL [C]

Identifier: 146343463

GI number: 146343463

Start: 6953488

End: 6954777

Strand: Reverse

Name: pqqL [C]

Synonym: BRADO6692

Alternate gene names: 146343463

Gene position: 6954777-6953488 (Counterclockwise)

Preceding gene: 146343464

Following gene: 146343462

Centisome position: 93.27

GC content: 68.06

Gene sequence:

>1290_bases
ATGGGTGTGGAAGTCACGAAGCTGCCGACCGGACTGACCGTCGTCACCGACACGATGCCGCATCTGGAGACCGCCGCGCT
CGGCGTCTGGGCCGGCGTCGGCGGCCGCGACGAGAAGCCGGACGAGCATGGCATCTCGCATCTGCTCGAGCACATGGCCT
TCAAGGGCACGACGACGCGCAGCGCGCGCGAGATTGTCGAGGCGATCGAGGCCGTCGGCGGTGACCTCAATGCCGGCACC
TCGACCGAGACCACGGCCTATTACGCCCGCGTGCTGAAGGCCGACGTGCCGCTGGCGCTCGACGTGCTCTCGGACATCCT
CGCCAACCCGTCCTTCGTGCCGGAGGAGCTGGAGCGCGAGAAGAACGTCATCGTGCAGGAGATCGGCGCCGCGCAGGACA
CGCCCGACGACGTCGTGTTCGAGCATCTCAACGAACTGTGCTTCCCGGACCAGCCGATGGGGCGCTCGCTGCTCGGCACC
GCCAAGACGCTCGAGGCATTCGATCGCGACAAGCTGCACGGCTATCTGTCGACGCATTATCGCGGGCCCGACATGGTCGT
CGCCGCCGCCGGCGCCGTCGATCATCATCGCGTGGTCGAGGATGTGAGCAGGCGATTCGCCAGTTTCAACGGCGGCGAGG
GGCCGAAGCCGCAGCCGGCGGCGTTCGGCAAGGGCGGCTCGCGGGTCGTGCATCGCGACCTTGAGCAGGCGCATCTGACC
TTGGCGCTCGAGGGCGTGCCGCAGGCCGACCCGTCACTGTTCTCGCTGCAGGTGTTCACCAACATCCTCGGCGGCGGCAT
GTCGTCCCGGCTGTTCCAAGAGGTGCGCGAGAACCGCGGGCTCTGCTACTCCGTCTACACGTTCCACGCGCCCTACAGCG
ACACCGGCTTCTTCGGGCTCTACACCGGCACCGATCCGGCCGACGCGCCCGAGATGATGGAGGTCGTGGTCGACATCATC
GGCAATGCGGTGGAGACGCTGAGCGAGGCCGAGGTCGCCCGCGCCAAGGCGCAGATGAAGGCGGGGCTGCTGATGGCGCT
GGAAAGCTGCAGCGCCCGCGCCGAGCAGCTCGCCCGCCATATTCTGGCTTACGGCCGGCCTCAGACCTTGCAGGAGATGG
TCGCCAAGATCGAGGCCGTCAGCGTCGAGAGCACGCGCGATGCGGCGCGTGCGCTCCTCGCACGCAGCAAGCCGGCGGTG
GTCGCGCTCGGCAGCGGCAGGGGTCTGGACACGGCGGTGACTTTCGCCGAAGGTCTCGCCGGGCCGAAATCCAAGGCTCA
GCTGCATTGA

Upstream 100 bases:

>100_bases
TGAGCAAGCGCGAGGACGCAAAGATCATGCGGAACGAGCAGGCCGAGGTGGAAAAATTCATCCGCTCGGTCAGCCGGGCC
GCCAAGCAGGGAATTGCATG

Downstream 100 bases:

>100_bases
GCACGAGCCCGAAAGGCCCGGAGATGTTGGGAATCGCGGTCGTCAGGCCCGCCATTCGCCGATCGAAGGGCTGAAGAGCA
GGGGGAGCATCACCGATGGC

Product: putative zinc protease (mpp-like)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 429; Mature: 428

Protein sequence:

>429_residues
MGVEVTKLPTGLTVVTDTMPHLETAALGVWAGVGGRDEKPDEHGISHLLEHMAFKGTTTRSAREIVEAIEAVGGDLNAGT
STETTAYYARVLKADVPLALDVLSDILANPSFVPEELEREKNVIVQEIGAAQDTPDDVVFEHLNELCFPDQPMGRSLLGT
AKTLEAFDRDKLHGYLSTHYRGPDMVVAAAGAVDHHRVVEDVSRRFASFNGGEGPKPQPAAFGKGGSRVVHRDLEQAHLT
LALEGVPQADPSLFSLQVFTNILGGGMSSRLFQEVRENRGLCYSVYTFHAPYSDTGFFGLYTGTDPADAPEMMEVVVDII
GNAVETLSEAEVARAKAQMKAGLLMALESCSARAEQLARHILAYGRPQTLQEMVAKIEAVSVESTRDAARALLARSKPAV
VALGSGRGLDTAVTFAEGLAGPKSKAQLH

Sequences:

>Translated_429_residues
MGVEVTKLPTGLTVVTDTMPHLETAALGVWAGVGGRDEKPDEHGISHLLEHMAFKGTTTRSAREIVEAIEAVGGDLNAGT
STETTAYYARVLKADVPLALDVLSDILANPSFVPEELEREKNVIVQEIGAAQDTPDDVVFEHLNELCFPDQPMGRSLLGT
AKTLEAFDRDKLHGYLSTHYRGPDMVVAAAGAVDHHRVVEDVSRRFASFNGGEGPKPQPAAFGKGGSRVVHRDLEQAHLT
LALEGVPQADPSLFSLQVFTNILGGGMSSRLFQEVRENRGLCYSVYTFHAPYSDTGFFGLYTGTDPADAPEMMEVVVDII
GNAVETLSEAEVARAKAQMKAGLLMALESCSARAEQLARHILAYGRPQTLQEMVAKIEAVSVESTRDAARALLARSKPAV
VALGSGRGLDTAVTFAEGLAGPKSKAQLH
>Mature_428_residues
GVEVTKLPTGLTVVTDTMPHLETAALGVWAGVGGRDEKPDEHGISHLLEHMAFKGTTTRSAREIVEAIEAVGGDLNAGTS
TETTAYYARVLKADVPLALDVLSDILANPSFVPEELEREKNVIVQEIGAAQDTPDDVVFEHLNELCFPDQPMGRSLLGTA
KTLEAFDRDKLHGYLSTHYRGPDMVVAAAGAVDHHRVVEDVSRRFASFNGGEGPKPQPAAFGKGGSRVVHRDLEQAHLTL
ALEGVPQADPSLFSLQVFTNILGGGMSSRLFQEVRENRGLCYSVYTFHAPYSDTGFFGLYTGTDPADAPEMMEVVVDIIG
NAVETLSEAEVARAKAQMKAGLLMALESCSARAEQLARHILAYGRPQTLQEMVAKIEAVSVESTRDAARALLARSKPAVV
ALGSGRGLDTAVTFAEGLAGPKSKAQLH

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=412, Percent_Identity=34.2233009708738, Blast_Score=249, Evalue=5e-66,
Organism=Homo sapiens, GI46593007, Length=416, Percent_Identity=32.4519230769231, Blast_Score=206, Evalue=4e-53,
Organism=Homo sapiens, GI24308013, Length=456, Percent_Identity=25.8771929824561, Blast_Score=131, Evalue=1e-30,
Organism=Homo sapiens, GI50592988, Length=414, Percent_Identity=25.1207729468599, Blast_Score=118, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71999683, Length=411, Percent_Identity=30.1703163017032, Blast_Score=201, Evalue=7e-52,
Organism=Caenorhabditis elegans, GI17553678, Length=424, Percent_Identity=29.0094339622642, Blast_Score=156, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI17510601, Length=455, Percent_Identity=24.6153846153846, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI17569737, Length=401, Percent_Identity=23.1920199501247, Blast_Score=71, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI17555260, Length=399, Percent_Identity=22.3057644110276, Blast_Score=71, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323192, Length=423, Percent_Identity=33.806146572104, Blast_Score=253, Evalue=3e-68,
Organism=Saccharomyces cerevisiae, GI6321813, Length=442, Percent_Identity=27.8280542986425, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6319426, Length=432, Percent_Identity=25.9259259259259, Blast_Score=117, Evalue=4e-27,
Organism=Drosophila melanogaster, GI21357875, Length=411, Percent_Identity=34.3065693430657, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI24646943, Length=411, Percent_Identity=34.3065693430657, Blast_Score=238, Evalue=7e-63,
Organism=Drosophila melanogaster, GI19921772, Length=452, Percent_Identity=25.4424778761062, Blast_Score=130, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24665395, Length=383, Percent_Identity=24.2819843342037, Blast_Score=72, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 45884; Mature: 45753

Theoretical pI: Translated: 5.01; Mature: 5.01

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGVEVTKLPTGLTVVTDTMPHLETAALGVWAGVGGRDEKPDEHGISHLLEHMAFKGTTTR
CCCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
SAREIVEAIEAVGGDLNAGTSTETTAYYARVLKADVPLALDVLSDILANPSFVPEELERE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHH
KNVIVQEIGAAQDTPDDVVFEHLNELCFPDQPMGRSLLGTAKTLEAFDRDKLHGYLSTHY
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGPDMVVAAAGAVDHHRVVEDVSRRFASFNGGEGPKPQPAAFGKGGSRVVHRDLEQAHLT
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEE
LALEGVPQADPSLFSLQVFTNILGGGMSSRLFQEVRENRGLCYSVYTFHAPYSDTGFFGL
EEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEE
YTGTDPADAPEMMEVVVDIIGNAVETLSEAEVARAKAQMKAGLLMALESCSARAEQLARH
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAYGRPQTLQEMVAKIEAVSVESTRDAARALLARSKPAVVALGSGRGLDTAVTFAEGLA
HHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCC
GPKSKAQLH
CCCCCCCCC
>Mature Secondary Structure 
GVEVTKLPTGLTVVTDTMPHLETAALGVWAGVGGRDEKPDEHGISHLLEHMAFKGTTTR
CCEEEECCCCCEEEECCCCHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCH
SAREIVEAIEAVGGDLNAGTSTETTAYYARVLKADVPLALDVLSDILANPSFVPEELERE
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHH
KNVIVQEIGAAQDTPDDVVFEHLNELCFPDQPMGRSLLGTAKTLEAFDRDKLHGYLSTHY
HHHHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCC
RGPDMVVAAAGAVDHHRVVEDVSRRFASFNGGEGPKPQPAAFGKGGSRVVHRDLEQAHLT
CCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHEE
LALEGVPQADPSLFSLQVFTNILGGGMSSRLFQEVRENRGLCYSVYTFHAPYSDTGFFGL
EEECCCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCEEE
YTGTDPADAPEMMEVVVDIIGNAVETLSEAEVARAKAQMKAGLLMALESCSARAEQLARH
ECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILAYGRPQTLQEMVAKIEAVSVESTRDAARALLARSKPAVVALGSGRGLDTAVTFAEGLA
HHHCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHCC
GPKSKAQLH
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA