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The map label for this gene is minC [H]

Identifier: 146343344

GI number: 146343344

Start: 6818404

End: 6819108

Strand: Reverse

Name: minC [H]

Synonym: BRADO6570

Alternate gene names: 146343344

Gene position: 6819108-6818404 (Counterclockwise)

Preceding gene: 146343349

Following gene: 146343343

Centisome position: 91.45

GC content: 66.1

Gene sequence:

>705_bases
TTGGGTCGGATGGTCATGAGTGCCAGCGCTGAAACGGTGCGTCCTGTAATTCGTCTGCGCGGGCGCTCCTACGTCGCCTT
CGTGTTCTCGCCGGTGGTCCCCATTGCCGACTGGCTCGGCGAGCTCGATGCGATGCTCGCGGGCTCTCCCGGCTTCTTCG
TCGGCAAGCCGATCGTGCTCGATCTCTCCGCCGTCGATCTCAGCCCGCTCGCCATCACCCACCTCATCAAGAGCATCGAG
TCGCGCAACATCCGCGTACTCGGCCTCGAAGGCGTCGAGCAGGGGCGCCTCTCGCTCGGCATGCCGCCATTGCTGTCGGG
CGGACGCCAATGCGCGGTGCAGGAGATCGAGCCCGAGAAGCCGTCTCTGCAGCAGCCGACCTCCTTGCTGCTCGATCAGC
CCGTGCGCTCCGGACAATCGATCGTGTTTCCCGATGGCGACGTCACCGTGCTCGGCGCGGTGTCCTCGGGCGCGGAGATC
GTCGCCGGCGGATCGATCCATGTCTACGGCGCGCTGCGCGGCCGCGCGATGGCCGGCATCAACGGCAATTCGGCGGCGCG
AATCTATTGCCAGAAGATCGAGGCCGAGCTGGTCGCGATCGACGGCTACTACCAGACCGCCGAGCAGATCGACGCCGGGC
TGCGTGGCAAGGCCGCGCAGGCGCGGCTCGAAGGTCATTCCATGAAGATCGTAGCTTTGAGCTGA

Upstream 100 bases:

>100_bases
GCATGTCGGGCGCGCCGCTGTCGATTTTCGAGCGGCTTAGCGTCGATTTAACCATCCGTTAACCATCTGGCGCCGACAGT
TAACCAATCGCTAAGAAGGG

Downstream 100 bases:

>100_bases
GTAGCAGGAGGATTCGCAAAATGGCTAAGGTTCTTGTTGTGACGTCGGGCAAGGGTGGCGTCGGAAAGACCACCACGACG
GCGGCGATGGGCGCGGCGCT

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 233

Protein sequence:

>234_residues
MGRMVMSASAETVRPVIRLRGRSYVAFVFSPVVPIADWLGELDAMLAGSPGFFVGKPIVLDLSAVDLSPLAITHLIKSIE
SRNIRVLGLEGVEQGRLSLGMPPLLSGGRQCAVQEIEPEKPSLQQPTSLLLDQPVRSGQSIVFPDGDVTVLGAVSSGAEI
VAGGSIHVYGALRGRAMAGINGNSAARIYCQKIEAELVAIDGYYQTAEQIDAGLRGKAAQARLEGHSMKIVALS

Sequences:

>Translated_234_residues
MGRMVMSASAETVRPVIRLRGRSYVAFVFSPVVPIADWLGELDAMLAGSPGFFVGKPIVLDLSAVDLSPLAITHLIKSIE
SRNIRVLGLEGVEQGRLSLGMPPLLSGGRQCAVQEIEPEKPSLQQPTSLLLDQPVRSGQSIVFPDGDVTVLGAVSSGAEI
VAGGSIHVYGALRGRAMAGINGNSAARIYCQKIEAELVAIDGYYQTAEQIDAGLRGKAAQARLEGHSMKIVALS
>Mature_233_residues
GRMVMSASAETVRPVIRLRGRSYVAFVFSPVVPIADWLGELDAMLAGSPGFFVGKPIVLDLSAVDLSPLAITHLIKSIES
RNIRVLGLEGVEQGRLSLGMPPLLSGGRQCAVQEIEPEKPSLQQPTSLLLDQPVRSGQSIVFPDGDVTVLGAVSSGAEIV
AGGSIHVYGALRGRAMAGINGNSAARIYCQKIEAELVAIDGYYQTAEQIDAGLRGKAAQARLEGHSMKIVALS

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization [H]

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family [H]

Homologues:

Organism=Escherichia coli, GI1787424, Length=202, Percent_Identity=36.1386138613861, Blast_Score=127, Evalue=6e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526 [H]

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N [H]

EC number: NA

Molecular weight: Translated: 24661; Mature: 24530

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGRMVMSASAETVRPVIRLRGRSYVAFVFSPVVPIADWLGELDAMLAGSPGFFVGKPIVL
CCCEEECCCHHHHHHHHHHCCCEEEEEEHHCHHHHHHHHHHHHHHHCCCCCCEECCCEEE
DLSAVDLSPLAITHLIKSIESRNIRVLGLEGVEQGRLSLGMPPLLSGGRQCAVQEIEPEK
EEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCHHHCCCCEEEEECCCCCC
PSLQQPTSLLLDQPVRSGQSIVFPDGDVTVLGAVSSGAEIVAGGSIHVYGALRGRAMAGI
CCCCCCHHHHHHCHHCCCCEEEECCCCEEEEEECCCCCEEEECCEEEEEEEECCCEEECC
NGNSAARIYCQKIEAELVAIDGYYQTAEQIDAGLRGKAAQARLEGHSMKIVALS
CCCCEEEEEEEEECEEEEEECCHHHHHHHHCCCCCCCHHHHEECCCEEEEEEEC
>Mature Secondary Structure 
GRMVMSASAETVRPVIRLRGRSYVAFVFSPVVPIADWLGELDAMLAGSPGFFVGKPIVL
CCEEECCCHHHHHHHHHHCCCEEEEEEHHCHHHHHHHHHHHHHHHCCCCCCEECCCEEE
DLSAVDLSPLAITHLIKSIESRNIRVLGLEGVEQGRLSLGMPPLLSGGRQCAVQEIEPEK
EEECCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCEECCCCHHHCCCCEEEEECCCCCC
PSLQQPTSLLLDQPVRSGQSIVFPDGDVTVLGAVSSGAEIVAGGSIHVYGALRGRAMAGI
CCCCCCHHHHHHCHHCCCCEEEECCCCEEEEEECCCCCEEEECCEEEEEEEECCCEEECC
NGNSAARIYCQKIEAELVAIDGYYQTAEQIDAGLRGKAAQARLEGHSMKIVALS
CCCCEEEEEEEEECEEEEEECCHHHHHHHHCCCCCCCHHHHEECCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]