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The map label for this gene is metX [H]

Identifier: 146343241

GI number: 146343241

Start: 6713863

End: 6715086

Strand: Reverse

Name: metX [H]

Synonym: BRADO6461

Alternate gene names: 146343241

Gene position: 6715086-6713863 (Counterclockwise)

Preceding gene: 146343245

Following gene: 146343240

Centisome position: 90.06

GC content: 66.26

Gene sequence:

>1224_bases
GTGAGAGACATGACAGGCCTGACGCCGAAATCCACCTCCGCGCTGCGCACGGTTGCGCCGGAAGAGCGTTCGCACGAGGT
CGACCATCCGAGCTCGCTTGTGGCGCAGTTCGGCGCCGACAAGCCGTTGAAGCTCGATTGCGGCGTCGATCTCACGCCGT
TCCAGATCGCCTACCAGACCTATGGCGAGCTCAACGCCGACAAGTCCAACGCCGTCCTGATCTGCCACGCGCTGACCGGC
GACCAGCACGTCGCCAACCGCCATCCCGTCACCGGCAAGCCCGGCTGGTGGGAGACGCTGGTCGGCCCCGGACGTCCGCT
CGATCCCGCGCGCTACTTCATCATCTGCTCCAACGTGATCGGCGGCTGCATGGGCTCGACCGGCCCGGCCTCGCTGAATC
CCGCGACCGGCAAGGTCTGGGGGCTCGATTTCCCGATCATCACCATCCCCGACATGGTGCGCGCGCAGGCGATGCTGATC
GACCATCTCGGCATCGACACGCTGTTCGCGGTGGTCGGCGGCTCCATGGGCGGCATGCAGGCGCTGCAATGGACGGTGGC
CTATCCTAGCCGCGTGTTCGCCAATCTCGCGATCGCCTGCGCGACGCGGCACTCGGCGCAGAACATCGCCTTCCACGAGC
TCGGCCGCCAGGCTGTGATGGCCGATCCGGAATGGGACCACGGCCGCTATGCCGACAAGGGCACGCATCCGCATCGCGGG
CTCGCGGTCGCGCGGATGGCCGCGCATATCACCTATCTGTCGGACGCCGCCCTGCATCGCAAGTTCGGCCGCCGCATGCA
GGACCGCGAGCTGCCGACGTTCTCGTTCGACGCCGATTTCCAGGTCGAGAGCTACCTGCGCTACCAGGGCTCGTCCTTCG
TCGAGCGCTTCGACGCCAATTCCTATCTCTATCTGACGCGCGCGATGGACTACTTCGACATCGCGGCGGATCACGACGGT
GTGCTTGCGGCGGCGTTCCGGGGCATCAAGACCCGCTTCTGCGTCGTGTCGTTCACCAGCGACTGGCTGTTTCCGACCTC
GGAGTCGCGGGCGCTGGTGCATGCGCTAAATGCGTCGAGCGCGCGGGTGTCGTTCGCGGAGATCGAGACCGACAAGGGAC
ATGACGCGTTCCTGCTCGATGTGCCCGAGTTCTTCGAGATCGCCAGCGCCTTTCTCGACTCGGCTGGCAAGGCGCGCGGC
CTCAACGCCACGAAGGGGAGCTGA

Upstream 100 bases:

>100_bases
GGCCGGGGACGTTATCGATCCCGGCCGAACCCCAGTTCAGGCCGGGTTTTTCATGGCCTGATATGTCACGTGGTTCGGGA
GCCCTTGCCGGAAGGCCGGG

Downstream 100 bases:

>100_bases
GCCATGAGCCTGCAGGGTGTGCTGCCGCTGAACGGCTTTACAGGCGGCGAGGTGTTGGCCTATCGGCCGGATCATCTGCT
GGTCGCCGGCATGGTCGAGC

Product: homoserine O-acetyltransferase

Products: NA

Alternate protein names: Homoserine O-trans-acetylase; HTA; Homoserine transacetylase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRDMTGLTPKSTSALRTVAPEERSHEVDHPSSLVAQFGADKPLKLDCGVDLTPFQIAYQTYGELNADKSNAVLICHALTG
DQHVANRHPVTGKPGWWETLVGPGRPLDPARYFIICSNVIGGCMGSTGPASLNPATGKVWGLDFPIITIPDMVRAQAMLI
DHLGIDTLFAVVGGSMGGMQALQWTVAYPSRVFANLAIACATRHSAQNIAFHELGRQAVMADPEWDHGRYADKGTHPHRG
LAVARMAAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLTRAMDYFDIAADHDG
VLAAAFRGIKTRFCVVSFTSDWLFPTSESRALVHALNASSARVSFAEIETDKGHDAFLLDVPEFFEIASAFLDSAGKARG
LNATKGS

Sequences:

>Translated_407_residues
MRDMTGLTPKSTSALRTVAPEERSHEVDHPSSLVAQFGADKPLKLDCGVDLTPFQIAYQTYGELNADKSNAVLICHALTG
DQHVANRHPVTGKPGWWETLVGPGRPLDPARYFIICSNVIGGCMGSTGPASLNPATGKVWGLDFPIITIPDMVRAQAMLI
DHLGIDTLFAVVGGSMGGMQALQWTVAYPSRVFANLAIACATRHSAQNIAFHELGRQAVMADPEWDHGRYADKGTHPHRG
LAVARMAAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLTRAMDYFDIAADHDG
VLAAAFRGIKTRFCVVSFTSDWLFPTSESRALVHALNASSARVSFAEIETDKGHDAFLLDVPEFFEIASAFLDSAGKARG
LNATKGS
>Mature_407_residues
MRDMTGLTPKSTSALRTVAPEERSHEVDHPSSLVAQFGADKPLKLDCGVDLTPFQIAYQTYGELNADKSNAVLICHALTG
DQHVANRHPVTGKPGWWETLVGPGRPLDPARYFIICSNVIGGCMGSTGPASLNPATGKVWGLDFPIITIPDMVRAQAMLI
DHLGIDTLFAVVGGSMGGMQALQWTVAYPSRVFANLAIACATRHSAQNIAFHELGRQAVMADPEWDHGRYADKGTHPHRG
LAVARMAAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDANSYLYLTRAMDYFDIAADHDG
VLAAAFRGIKTRFCVVSFTSDWLFPTSESRALVHALNASSARVSFAEIETDKGHDAFLLDVPEFFEIASAFLDSAGKARG
LNATKGS

Specific function: Unknown

COG id: COG2021

COG function: function code E; Homoserine acetyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. HTA family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6324052, Length=224, Percent_Identity=40.625, Blast_Score=174, Evalue=3e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR008220 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =2.3.1.31 [H]

Molecular weight: Translated: 44475; Mature: 44475

Theoretical pI: Translated: 6.61; Mature: 6.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDMTGLTPKSTSALRTVAPEERSHEVDHPSSLVAQFGADKPLKLDCGVDLTPFQIAYQT
CCCCCCCCCCCCCHHHHCCCCHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
YGELNADKSNAVLICHALTGDQHVANRHPVTGKPGWWETLVGPGRPLDPARYFIICSNVI
HCCCCCCCCCEEEEEEEECCCCHHCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEECHHH
GGCMGSTGPASLNPATGKVWGLDFPIITIPDMVRAQAMLIDHLGIDTLFAVVGGSMGGMQ
HHCCCCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHH
ALQWTVAYPSRVFANLAIACATRHSAQNIAFHELGRQAVMADPEWDHGRYADKGTHPHRG
HEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCH
LAVARMAAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHCCCHHHHHHCCC
SYLYLTRAMDYFDIAADHDGVLAAAFRGIKTRFCVVSFTSDWLFPTSESRALVHALNASS
CEEEEEECCCHHEECCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCC
ARVSFAEIETDKGHDAFLLDVPEFFEIASAFLDSAGKARGLNATKGS
CEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDMTGLTPKSTSALRTVAPEERSHEVDHPSSLVAQFGADKPLKLDCGVDLTPFQIAYQT
CCCCCCCCCCCCCHHHHCCCCHHCCCCCCHHHHHHHHCCCCCEEEECCCCCCHHHHHHHH
YGELNADKSNAVLICHALTGDQHVANRHPVTGKPGWWETLVGPGRPLDPARYFIICSNVI
HCCCCCCCCCEEEEEEEECCCCHHCCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEECHHH
GGCMGSTGPASLNPATGKVWGLDFPIITIPDMVRAQAMLIDHLGIDTLFAVVGGSMGGMQ
HHCCCCCCCCCCCCCCCEEEECCCCEEECCHHHHHHHHHHHHCCHHHHHHHHCCCCCCHH
ALQWTVAYPSRVFANLAIACATRHSAQNIAFHELGRQAVMADPEWDHGRYADKGTHPHRG
HEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCH
LAVARMAAHITYLSDAALHRKFGRRMQDRELPTFSFDADFQVESYLRYQGSSFVERFDAN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCHHHHHHHCCCHHHHHHCCC
SYLYLTRAMDYFDIAADHDGVLAAAFRGIKTRFCVVSFTSDWLFPTSESRALVHALNASS
CEEEEEECCCHHEECCCCCCHHHHHHHCCCEEEEEEEECCCCCCCCCCCCEEEEEECCCC
ARVSFAEIETDKGHDAFLLDVPEFFEIASAFLDSAGKARGLNATKGS
CEEEEEEEECCCCCCEEEECCHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]