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The map label for this gene is lspA [H]

Identifier: 146342888

GI number: 146342888

Start: 6294663

End: 6295160

Strand: Direct

Name: lspA [H]

Synonym: BRADO6068

Alternate gene names: 146342888

Gene position: 6294663-6295160 (Clockwise)

Preceding gene: 146342887

Following gene: 146342889

Centisome position: 84.42

GC content: 65.46

Gene sequence:

>498_bases
ATGACCCCCCGCCTCCGTCTCGGCCTGCTCGCCGGCCTCGCCACGCTGGTCGTCGACCAGGCCACCAAGCTGTGGCTGCT
CTACGGATTCGACCTGGCCAACCGCGGCACCGTCAAGGTCACGCCGTTCTTCGATCTCGTGCTCGCGTGGAACATCGGCA
TCAGCTTCGGCTGGCTGCAGAACGACACCCCGCTGGCGCAATATGGCTTGATGGCGGTGAAGGCGATCGCGGTGGTGGCG
CTGGCGATCTGGATGGCGCGATCGGAAACGAAGCTCGCGACCGCGGCGCTGGGCTTGATCATCGGCGGCGCGATCGGCAA
CGGCATCGACCGGCTGGCCTATGGCGCGGTGGTCGATTTCGCGCTGTTCCACATCGAGATCGGCGGCACGGTCTACAACT
GGTACATCTTCAACATGGCCGACGTGGCGATCGTTGCCGGGGTGGCGGGCCTGCTGTATGACTCCTTCTTCGGGAGTCAC
GCCGCAAAAGCGCCCTGA

Upstream 100 bases:

>100_bases
GTCCTTTCCACCAACTGGCCGTCCGCGGTATGGGTCCCGGCGTACGCCGGGACGACAGCTGTGTTTGTCGCCGGCTTGGT
CGTCAACTCATTAGCTTGCA

Downstream 100 bases:

>100_bases
TCCGGGCCGATACCGGCCGATGCTCACCCGGAGCCAAGAGCCTGAGGTTCTTCACGTTTTCGGGATCGGCCTGACGACCG
GAAGGTGCGCATGCGGCGCG

Product: lipoprotein signal peptidase

Products: NA

Alternate protein names: Prolipoprotein signal peptidase; Signal peptidase II; SPase II [H]

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTPRLRLGLLAGLATLVVDQATKLWLLYGFDLANRGTVKVTPFFDLVLAWNIGISFGWLQNDTPLAQYGLMAVKAIAVVA
LAIWMARSETKLATAALGLIIGGAIGNGIDRLAYGAVVDFALFHIEIGGTVYNWYIFNMADVAIVAGVAGLLYDSFFGSH
AAKAP

Sequences:

>Translated_165_residues
MTPRLRLGLLAGLATLVVDQATKLWLLYGFDLANRGTVKVTPFFDLVLAWNIGISFGWLQNDTPLAQYGLMAVKAIAVVA
LAIWMARSETKLATAALGLIIGGAIGNGIDRLAYGAVVDFALFHIEIGGTVYNWYIFNMADVAIVAGVAGLLYDSFFGSH
AAKAP
>Mature_164_residues
TPRLRLGLLAGLATLVVDQATKLWLLYGFDLANRGTVKVTPFFDLVLAWNIGISFGWLQNDTPLAQYGLMAVKAIAVVAL
AIWMARSETKLATAALGLIIGGAIGNGIDRLAYGAVVDFALFHIEIGGTVYNWYIFNMADVAIVAGVAGLLYDSFFGSHA
AKAP

Specific function: This protein specifically catalyzes the removal of signal peptides from prolipoproteins [H]

COG id: COG0597

COG function: function code MU; Lipoprotein signal peptidase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase A8 family [H]

Homologues:

Organism=Escherichia coli, GI1786210, Length=153, Percent_Identity=34.640522875817, Blast_Score=66, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001872 [H]

Pfam domain/function: PF01252 Peptidase_A8 [H]

EC number: =3.4.23.36 [H]

Molecular weight: Translated: 17592; Mature: 17461

Theoretical pI: Translated: 7.66; Mature: 7.66

Prosite motif: PS00855 SPASE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRLRLGLLAGLATLVVDQATKLWLLYGFDLANRGTVKVTPFFDLVLAWNIGISFGWLQ
CCCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEHHHHHHHHHHCCCEEEECC
NDTPLAQYGLMAVKAIAVVALAIWMARSETKLATAALGLIIGGAIGNGIDRLAYGAVVDF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALFHIEIGGTVYNWYIFNMADVAIVAGVAGLLYDSFFGSHAAKAP
HHEEEEECCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPRLRLGLLAGLATLVVDQATKLWLLYGFDLANRGTVKVTPFFDLVLAWNIGISFGWLQ
CCCHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCEEEEEHHHHHHHHHHCCCEEEECC
NDTPLAQYGLMAVKAIAVVALAIWMARSETKLATAALGLIIGGAIGNGIDRLAYGAVVDF
CCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
ALFHIEIGGTVYNWYIFNMADVAIVAGVAGLLYDSFFGSHAAKAP
HHEEEEECCEEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA