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The map label for this gene is ygjG [C]

Identifier: 146342881

GI number: 146342881

Start: 6284386

End: 6285729

Strand: Direct

Name: ygjG [C]

Synonym: BRADO6061

Alternate gene names: 146342881

Gene position: 6284386-6285729 (Clockwise)

Preceding gene: 146342880

Following gene: 146342882

Centisome position: 84.28

GC content: 67.11

Gene sequence:

>1344_bases
ATGCTGGACAAGAGCCCCCGCCCCGCCGTCACCGTTCCGAATGATCTTGCCGCGCATTGGATGCCGTTCACCGCGAACCG
CGCCTTCAAGAAGAATCCGCGCCTGCTCGCCGGCGCCAAGGGCATGCACTACATCACCGTCGATGGCCGCAACATCATCG
ATGCCGCAGCCGGCATGTGGTGCTGCAACGCCGGCCATGGCCGCACCGAGATCGCCGAGGCGATCGGCAAGCAGGCCGCA
GCGCTCGACTATGCGCCGCCGTTCCAGTTCGGCATTCCCCAGGCCTTCGAGCTCGCCAACCGCATCGCCGATCTCGCCCC
CGCCGGGCTGGACCATGTGTTCTTCTGCAACTCCGGCTCGGAGGCCGCCGACACCGCGCTGAAGATGGCGCTCGCCTATC
ACCAGATCAACGGCCAGGGCAGCCGCACCCGCCTGATCGGCCGCGTCCGCGGCTATCACGGCGTCGGCTTCGGCGGCACC
TCGGTCGGCGGCATCGTCAACAACCGCAAGCTGTTCGGCACGCTGCTCACGGGCGTCGACCACATTCCGGCGACCTATGA
CCGCGAGAAGCAGGCCTTCACCAAGGGCGAGCCTGAATACGGCGCGCACTTCGCCGAGGAGCTGGAAAACCTCGTCGCGT
TGCACGGCGCCAACACCATCGCTGCCGTCATCGTCGAGCCGATGGCCGGCTCCACCGGCGTCATCCCCGCGCCGAAGGGC
TATCTCAAGCGCCTGCGCGAGATCACCCAGAAGCACGGCATCCTCCTGATCTTCGACGAGGTCATCACCGGCTTCGGCCG
TCTCGGCCACGCCTTCGCCGCCGAGCGCTATGGCGTGACGCCGGACCTCTTGACCTTCGCCAAGGGCGTCACCAACGGCG
CGGCGCCGATGGGCGGCGTGCTGGTGCGCGACACCATCCACGACGCCTTCATGAGCGGCCCGGAGCACATGGTCGAGTTC
ACCCACGGCTACACCTACTCGGCGCATCCGATCGCCTGCGCCGCCGGCCTCGCCACGCTCGACATCTATCGCGACCACAA
GCTGTTCGAGCATGCCAAGGCGATCGAGCCGAAATGGGCCGACGCCGTGATGTCGCTGAAGGGGCTGCCCAACGTCCTCG
ACATCCGCACCGTTGGTCTGACCGCCGGCATCGACCTCGCCCCGCTGCCCGACGCCGTCGGCAAGCGCGGCTACTCCGCG
ATGGAGCAGGCCTTCCACAACACCGACCTGATGCTGCGCATCGCCGGCGATACCCTGGCTCTGACCCCGCCGCTGATCAT
CAACGAGGACCAGATCGGCGAGATCGTCGAGAAGGTCGGCAAGGTTATCAAGGCCGTGGCGTAA

Upstream 100 bases:

>100_bases
GCACGATCCGTTTCGGTCAGTGTCTGGCAATCGCTCCGCCACCTTTCCGGGTCATGCTGTCGCCGTCGTACAATCTGCCT
CAACTCCCCGAGAGGTCCCC

Downstream 100 bases:

>100_bases
GCCGCGCGGCATCGTCATCAATCACGACAAAATGGCGGCCCCCGTGGCCGCCATTTTCGTTGTTCCTCCAACGACGTCAT
TCCGGGGCAATCGTCATGTA

Product: beta alanine--pyruvate transaminase

Products: NA

Alternate protein names: Omega-APT; Beta-alanine--pyruvate aminotransferase [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MLDKSPRPAVTVPNDLAAHWMPFTANRAFKKNPRLLAGAKGMHYITVDGRNIIDAAAGMWCCNAGHGRTEIAEAIGKQAA
ALDYAPPFQFGIPQAFELANRIADLAPAGLDHVFFCNSGSEAADTALKMALAYHQINGQGSRTRLIGRVRGYHGVGFGGT
SVGGIVNNRKLFGTLLTGVDHIPATYDREKQAFTKGEPEYGAHFAEELENLVALHGANTIAAVIVEPMAGSTGVIPAPKG
YLKRLREITQKHGILLIFDEVITGFGRLGHAFAAERYGVTPDLLTFAKGVTNGAAPMGGVLVRDTIHDAFMSGPEHMVEF
THGYTYSAHPIACAAGLATLDIYRDHKLFEHAKAIEPKWADAVMSLKGLPNVLDIRTVGLTAGIDLAPLPDAVGKRGYSA
MEQAFHNTDLMLRIAGDTLALTPPLIINEDQIGEIVEKVGKVIKAVA

Sequences:

>Translated_447_residues
MLDKSPRPAVTVPNDLAAHWMPFTANRAFKKNPRLLAGAKGMHYITVDGRNIIDAAAGMWCCNAGHGRTEIAEAIGKQAA
ALDYAPPFQFGIPQAFELANRIADLAPAGLDHVFFCNSGSEAADTALKMALAYHQINGQGSRTRLIGRVRGYHGVGFGGT
SVGGIVNNRKLFGTLLTGVDHIPATYDREKQAFTKGEPEYGAHFAEELENLVALHGANTIAAVIVEPMAGSTGVIPAPKG
YLKRLREITQKHGILLIFDEVITGFGRLGHAFAAERYGVTPDLLTFAKGVTNGAAPMGGVLVRDTIHDAFMSGPEHMVEF
THGYTYSAHPIACAAGLATLDIYRDHKLFEHAKAIEPKWADAVMSLKGLPNVLDIRTVGLTAGIDLAPLPDAVGKRGYSA
MEQAFHNTDLMLRIAGDTLALTPPLIINEDQIGEIVEKVGKVIKAVA
>Mature_447_residues
MLDKSPRPAVTVPNDLAAHWMPFTANRAFKKNPRLLAGAKGMHYITVDGRNIIDAAAGMWCCNAGHGRTEIAEAIGKQAA
ALDYAPPFQFGIPQAFELANRIADLAPAGLDHVFFCNSGSEAADTALKMALAYHQINGQGSRTRLIGRVRGYHGVGFGGT
SVGGIVNNRKLFGTLLTGVDHIPATYDREKQAFTKGEPEYGAHFAEELENLVALHGANTIAAVIVEPMAGSTGVIPAPKG
YLKRLREITQKHGILLIFDEVITGFGRLGHAFAAERYGVTPDLLTFAKGVTNGAAPMGGVLVRDTIHDAFMSGPEHMVEF
THGYTYSAHPIACAAGLATLDIYRDHKLFEHAKAIEPKWADAVMSLKGLPNVLDIRTVGLTAGIDLAPLPDAVGKRGYSA
MEQAFHNTDLMLRIAGDTLALTPPLIINEDQIGEIVEKVGKVIKAVA

Specific function: Catalyzes transamination between a variety of omega- amino acids, mono and diamines, and pyruvate. Plays a pivotal role in the metabolism of the omega amino acids [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=414, Percent_Identity=26.8115942028986, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI13994255, Length=440, Percent_Identity=26.1363636363636, Blast_Score=119, Evalue=6e-27,
Organism=Homo sapiens, GI37574042, Length=434, Percent_Identity=26.4976958525346, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI226442705, Length=434, Percent_Identity=26.7281105990783, Blast_Score=113, Evalue=3e-25,
Organism=Homo sapiens, GI226442709, Length=398, Percent_Identity=27.6381909547739, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI284507298, Length=329, Percent_Identity=27.6595744680851, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI24119277, Length=439, Percent_Identity=25.5125284738041, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI188536080, Length=283, Percent_Identity=24.7349823321555, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38679950, Length=283, Percent_Identity=24.7349823321555, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI38679946, Length=283, Percent_Identity=24.7349823321555, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI145693181, Length=407, Percent_Identity=28.2555282555283, Blast_Score=155, Evalue=5e-39,
Organism=Escherichia coli, GI1786991, Length=428, Percent_Identity=28.5046728971963, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1789759, Length=399, Percent_Identity=28.8220551378446, Blast_Score=140, Evalue=2e-34,
Organism=Escherichia coli, GI1788044, Length=387, Percent_Identity=29.7157622739018, Blast_Score=135, Evalue=8e-33,
Organism=Escherichia coli, GI1789016, Length=355, Percent_Identity=28.169014084507, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787560, Length=343, Percent_Identity=29.1545189504373, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786349, Length=365, Percent_Identity=27.6712328767123, Blast_Score=89, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI32564660, Length=445, Percent_Identity=28.0898876404494, Blast_Score=136, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI71992977, Length=440, Percent_Identity=27.5, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI25144271, Length=424, Percent_Identity=25.7075471698113, Blast_Score=121, Evalue=7e-28,
Organism=Caenorhabditis elegans, GI25144274, Length=244, Percent_Identity=31.1475409836066, Blast_Score=107, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6323470, Length=442, Percent_Identity=25.7918552036199, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6324386, Length=424, Percent_Identity=25.7075471698113, Blast_Score=125, Evalue=1e-29,
Organism=Saccharomyces cerevisiae, GI6324432, Length=421, Percent_Identity=27.0783847980998, Blast_Score=120, Evalue=5e-28,
Organism=Drosophila melanogaster, GI21357415, Length=430, Percent_Identity=25.8139534883721, Blast_Score=125, Evalue=6e-29,
Organism=Drosophila melanogaster, GI161085790, Length=428, Percent_Identity=26.4018691588785, Blast_Score=116, Evalue=3e-26,
Organism=Drosophila melanogaster, GI28574759, Length=411, Percent_Identity=27.007299270073, Blast_Score=114, Evalue=1e-25,
Organism=Drosophila melanogaster, GI21356575, Length=431, Percent_Identity=24.8259860788863, Blast_Score=99, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.18 [H]

Molecular weight: Translated: 47786; Mature: 47786

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDKSPRPAVTVPNDLAAHWMPFTANRAFKKNPRLLAGAKGMHYITVDGRNIIDAAAGMW
CCCCCCCCCEECCCHHHHHCCCCCCCCCCCCCCCEEECCCCCEEEEECCCHHHHHHCCCE
CCNAGHGRTEIAEAIGKQAAALDYAPPFQFGIPQAFELANRIADLAPAGLDHVFFCNSGS
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
EAADTALKMALAYHQINGQGSRTRLIGRVRGYHGVGFGGTSVGGIVNNRKLFGTLLTGVD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
HIPATYDREKQAFTKGEPEYGAHFAEELENLVALHGANTIAAVIVEPMAGSTGVIPAPKG
CCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHH
YLKRLREITQKHGILLIFDEVITGFGRLGHAFAAERYGVTPDLLTFAKGVTNGAAPMGGV
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCE
LVRDTIHDAFMSGPEHMVEFTHGYTYSAHPIACAAGLATLDIYRDHKLFEHAKAIEPKWA
EHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
DAVMSLKGLPNVLDIRTVGLTAGIDLAPLPDAVGKRGYSAMEQAFHNTDLMLRIAGDTLA
HHHHHHHCCCCHHEEEEECEECCCCCCCCCHHHHHCCHHHHHHHHCCCCEEEEECCCEEE
LTPPLIINEDQIGEIVEKVGKVIKAVA
ECCCEEECCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLDKSPRPAVTVPNDLAAHWMPFTANRAFKKNPRLLAGAKGMHYITVDGRNIIDAAAGMW
CCCCCCCCCEECCCHHHHHCCCCCCCCCCCCCCCEEECCCCCEEEEECCCHHHHHHCCCE
CCNAGHGRTEIAEAIGKQAAALDYAPPFQFGIPQAFELANRIADLAPAGLDHVFFCNSGS
EECCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCEEEEECCCC
EAADTALKMALAYHQINGQGSRTRLIGRVRGYHGVGFGGTSVGGIVNNRKLFGTLLTGVD
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCC
HIPATYDREKQAFTKGEPEYGAHFAEELENLVALHGANTIAAVIVEPMAGSTGVIPAPKG
CCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCHH
YLKRLREITQKHGILLIFDEVITGFGRLGHAFAAERYGVTPDLLTFAKGVTNGAAPMGGV
HHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCE
LVRDTIHDAFMSGPEHMVEFTHGYTYSAHPIACAAGLATLDIYRDHKLFEHAKAIEPKWA
EHHHHHHHHHHCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
DAVMSLKGLPNVLDIRTVGLTAGIDLAPLPDAVGKRGYSAMEQAFHNTDLMLRIAGDTLA
HHHHHHHCCCCHHEEEEECEECCCCCCCCCHHHHHCCHHHHHHHHCCCCEEEEECCCEEE
LTPPLIINEDQIGEIVEKVGKVIKAVA
ECCCEEECCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1618757; 6822556; 2500426 [H]