Click here to switch to the map view.

The map label for this gene is pgsA [H]

Identifier: 146342877

GI number: 146342877

Start: 6281788

End: 6282384

Strand: Direct

Name: pgsA [H]

Synonym: BRADO6057

Alternate gene names: 146342877

Gene position: 6281788-6282384 (Clockwise)

Preceding gene: 146342876

Following gene: 146342878

Centisome position: 84.24

GC content: 63.99

Gene sequence:

>597_bases
GTGCCCAGCAAGACGTCGACGTCTCTGCCGAACATCCTGACCTATGCGCGCATCGCCGCGATACCGGTCGTGGTCGGCTG
CATCTACGCGCAGTCCATCATGGACTACCCGCTGTGGCTGCGCTGGGTCGCCGTCGCGGTGTTCATCGCCGCCGGCATCA
CCGACTATCTCGACGGCTATTATGCCCGCATCTGGAACCAGCAGTCGGCGTTCGGCCGCATGCTGGACCCGATCGCCGAC
AAGCTGCTGGTCGCGTCGTGTCTGCTGATGCTCGCCGCCGACAACAGCATCCATGGCTGGACCTTATGGGCGGCGATCGT
GATCCTGTGCCGCGAGATCCTGGTGTCGGGGCTGCGCGAATATCTCGCCGCGCTGCGCGTCAGCGTGCCCGTGACCAAGG
TCGCCAAGTGGAAGACCACGATGCAGCTGATCGCGATCGGCTTCCTGCTGGCGGGCGAGGCCGGCGACCAGGTGGTTCCG
GTGGTGACGATGATCGGCATCGTGCTGCTGTGGGCCTCGGCGATCTTCACGATCTATACCGGCTACGATTATTTCCGCGC
CGGCATTCACCACCTCATCGAGGAAGACTCGCGATGA

Upstream 100 bases:

>100_bases
GCGTCATATCTGCGTCATCCTGCCCGGGCTGCCCGGCTCGGAGGTTGACGTTCGAACGGCGGCAGTATTGGTACACCGGA
TGAATATTGCGACCACACGC

Downstream 100 bases:

>100_bases
AGGTGAAGTATTTCGCCTGGGTGCGGGAGCGCATCGGCAAGGCCGAGGAGACCATCGAGCCGCCGGCCGATGTGCGTACC
GTGGGCGAGCTGATCGCCTG

Product: putative CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 198; Mature: 197

Protein sequence:

>198_residues
MPSKTSTSLPNILTYARIAAIPVVVGCIYAQSIMDYPLWLRWVAVAVFIAAGITDYLDGYYARIWNQQSAFGRMLDPIAD
KLLVASCLLMLAADNSIHGWTLWAAIVILCREILVSGLREYLAALRVSVPVTKVAKWKTTMQLIAIGFLLAGEAGDQVVP
VVTMIGIVLLWASAIFTIYTGYDYFRAGIHHLIEEDSR

Sequences:

>Translated_198_residues
MPSKTSTSLPNILTYARIAAIPVVVGCIYAQSIMDYPLWLRWVAVAVFIAAGITDYLDGYYARIWNQQSAFGRMLDPIAD
KLLVASCLLMLAADNSIHGWTLWAAIVILCREILVSGLREYLAALRVSVPVTKVAKWKTTMQLIAIGFLLAGEAGDQVVP
VVTMIGIVLLWASAIFTIYTGYDYFRAGIHHLIEEDSR
>Mature_197_residues
PSKTSTSLPNILTYARIAAIPVVVGCIYAQSIMDYPLWLRWVAVAVFIAAGITDYLDGYYARIWNQQSAFGRMLDPIADK
LLVASCLLMLAADNSIHGWTLWAAIVILCREILVSGLREYLAALRVSVPVTKVAKWKTTMQLIAIGFLLAGEAGDQVVPV
VTMIGIVLLWASAIFTIYTGYDYFRAGIHHLIEEDSR

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=192, Percent_Identity=36.4583333333333, Blast_Score=99, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6320059, Length=174, Percent_Identity=27.5862068965517, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 21883; Mature: 21752

Theoretical pI: Translated: 7.43; Mature: 7.43

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPSKTSTSLPNILTYARIAAIPVVVGCIYAQSIMDYPLWLRWVAVAVFIAAGITDYLDGY
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
YARIWNQQSAFGRMLDPIADKLLVASCLLMLAADNSIHGWTLWAAIVILCREILVSGLRE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YLAALRVSVPVTKVAKWKTTMQLIAIGFLLAGEAGDQVVPVVTMIGIVLLWASAIFTIYT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GYDYFRAGIHHLIEEDSR
CHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PSKTSTSLPNILTYARIAAIPVVVGCIYAQSIMDYPLWLRWVAVAVFIAAGITDYLDGY
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHH
YARIWNQQSAFGRMLDPIADKLLVASCLLMLAADNSIHGWTLWAAIVILCREILVSGLRE
HHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHH
YLAALRVSVPVTKVAKWKTTMQLIAIGFLLAGEAGDQVVPVVTMIGIVLLWASAIFTIYT
HHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
GYDYFRAGIHHLIEEDSR
CHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA