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The map label for this gene is oxlT [H]

Identifier: 146342669

GI number: 146342669

Start: 6052440

End: 6054095

Strand: Reverse

Name: oxlT [H]

Synonym: BRADO5836

Alternate gene names: 146342669

Gene position: 6054095-6052440 (Counterclockwise)

Preceding gene: 146342670

Following gene: 146342665

Centisome position: 81.19

GC content: 65.58

Gene sequence:

>1656_bases
ATGGCAACCATTGAGAGCGCGGGCTCGCTCCCGAACGCGCAAGCGGGCATCTTCGACCGTGAGCACACGGTCGCAAAGGC
GGGGTTCAACCGCTGGCTGGTTCCACCGGCGGCCCTGTGCATTCATCTGTGCATTGGCATGGCCTATGGCTTCTCGGTGT
TCTGGCTACCGCTGTCGCGCGCGATCGGCGTGACGCAGAGCACCGTCTGCACCGACATGACCCTGCTGCAGGAACTGTTC
ACGACCAGCTGCGACTGGAAGGTCGCGAGCCTCGGCTGGATGTACACGCTGTTCTTCGTGCTGCTCGGCGGCTCTGCGGC
GGTCTGGGGCGGCTGGCTGGAGCGGGCGGGCCCGCGCAAGGCCGGCGCGGTGGCGGCGTGCTGCTGGGGCGGCGGTCTGC
TGATCGCAGCGCTCGGCATCTATGTCCACCAGCTCTGGATGATGTGGCTCGGCGCCGGCGTGATCGGCGGCATCGGCCTC
GGTCTCGGCTACATCTCGCCGGTCTCGACCCTGGTAAAATGGTTCCCGGACCGTCGCGGCATGGCGACCGGCATGGCCAT
CATGGGGTTCGGCGGCGGCGCGATGATCGGTGCTCCGCTGGCCAACCTGCTGATGAACTACTTCAAGACCCCGACCTCGG
TCGGCGTCTGGGAGACCTTCGTCACGATGGGCGTGATCTATTTCGTGTTCATGATGATCGGCGCCTTCGCCTATCGCGTC
GCTCCGGTGGGCTGGCAGCCCGAGGGCTGGACGCCGCCGGCGGTGAAGAAGGCGATGATCTCCGAGCATCACGTGCATCT
CGATAACGCGCACAAGACCCCGCAGTTCTGGCTGGTCTGGTGGGTGCTGTGCTTGAACGTGTCGGCGGGCATCGGCGTCA
TCGGCATGGCTTCGCCGATGCTGCAGGAGATCTTCGCCGGCAAGCTGATCGGTCTGCCCGACGTCAGCTTCAACCAGCTC
GACGCCACGCAGAAGGCCACCGTCGCCGGCATCGCAGCCGGCTTTGCCGGCCTGCTGTCGCTGTTCAACATCGGCGGCCG
CTTCTTCTGGGCCTCGCTGTCCGACCACATCGGCCGCAAGGCGACCTATTACTGCTTCTTCCTGATCGGCATCGTGCTCT
ACGCGCTGGCGCCGACCTTCGCGGCGATGGGCTCGAAGCTGCTCTTCGTGGGCGCCTTTGCCATCATCCTCTCGATGTAT
GGCGGCGGCTTCGCGACGGTGCCGGCCTATCTCGCTGACCTGTTCGGCACTCAGTTCGTGGGCGCCATCCACGGCCGGCT
GCTGACGGCCTGGGCCACCGCCGGCATCATCGGTCCGGTGGTCGTCAACTACATCCGCGAGTTTCAGCTTGCCGCCGGCG
TGCCGCGCGACCAGCTGTACAACACCACGATGTACATCCTCTGCGCCATGCTGCTCGCCGGCCTGATCTGCAACTTCATG
ATCAAGCCCGTCGATCACAAGTGGAACATGAGCCCCGAAGAAGTGGCGCGCTACCAGGCTGAGCTCGCCAAGAGCGAGTC
GGCGATCCAGCACGGCTCGTTCGGCATCGGCAAGGGCGGCCTCGACCTGAGCTCGGCGCTGTTCTGGGCCTTCGTCGGCG
TGCCGCTGGCCTGGGGCGTCTGGAAGACGCTCGAAAGCGCGGTAAAGATCTTCTGA

Upstream 100 bases:

>100_bases
TAGGTCGACGGTCGGCAGGGTGAGTGAGCGTATTGATTCTGATCAAGGGGACAGAACATGACGTCGTTGCGTTTGACGGG
AGTCCGTAGGGGAGGAATGC

Downstream 100 bases:

>100_bases
TCCACCGATCGCGAAGCTTGCATGCGGGGCGGCCTGATCGGCCGCCCCGTTTTTTTGCCCATGCCAGAATAAGCGATTAG
CTTCGCCGTCCCGGCGCAGC

Product: major facilitator superfamily oxalate/formate antiporter permease

Products: NA

Alternate protein names: OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein [H]

Number of amino acids: Translated: 551; Mature: 550

Protein sequence:

>551_residues
MATIESAGSLPNAQAGIFDREHTVAKAGFNRWLVPPAALCIHLCIGMAYGFSVFWLPLSRAIGVTQSTVCTDMTLLQELF
TTSCDWKVASLGWMYTLFFVLLGGSAAVWGGWLERAGPRKAGAVAACCWGGGLLIAALGIYVHQLWMMWLGAGVIGGIGL
GLGYISPVSTLVKWFPDRRGMATGMAIMGFGGGAMIGAPLANLLMNYFKTPTSVGVWETFVTMGVIYFVFMMIGAFAYRV
APVGWQPEGWTPPAVKKAMISEHHVHLDNAHKTPQFWLVWWVLCLNVSAGIGVIGMASPMLQEIFAGKLIGLPDVSFNQL
DATQKATVAGIAAGFAGLLSLFNIGGRFFWASLSDHIGRKATYYCFFLIGIVLYALAPTFAAMGSKLLFVGAFAIILSMY
GGGFATVPAYLADLFGTQFVGAIHGRLLTAWATAGIIGPVVVNYIREFQLAAGVPRDQLYNTTMYILCAMLLAGLICNFM
IKPVDHKWNMSPEEVARYQAELAKSESAIQHGSFGIGKGGLDLSSALFWAFVGVPLAWGVWKTLESAVKIF

Sequences:

>Translated_551_residues
MATIESAGSLPNAQAGIFDREHTVAKAGFNRWLVPPAALCIHLCIGMAYGFSVFWLPLSRAIGVTQSTVCTDMTLLQELF
TTSCDWKVASLGWMYTLFFVLLGGSAAVWGGWLERAGPRKAGAVAACCWGGGLLIAALGIYVHQLWMMWLGAGVIGGIGL
GLGYISPVSTLVKWFPDRRGMATGMAIMGFGGGAMIGAPLANLLMNYFKTPTSVGVWETFVTMGVIYFVFMMIGAFAYRV
APVGWQPEGWTPPAVKKAMISEHHVHLDNAHKTPQFWLVWWVLCLNVSAGIGVIGMASPMLQEIFAGKLIGLPDVSFNQL
DATQKATVAGIAAGFAGLLSLFNIGGRFFWASLSDHIGRKATYYCFFLIGIVLYALAPTFAAMGSKLLFVGAFAIILSMY
GGGFATVPAYLADLFGTQFVGAIHGRLLTAWATAGIIGPVVVNYIREFQLAAGVPRDQLYNTTMYILCAMLLAGLICNFM
IKPVDHKWNMSPEEVARYQAELAKSESAIQHGSFGIGKGGLDLSSALFWAFVGVPLAWGVWKTLESAVKIF
>Mature_550_residues
ATIESAGSLPNAQAGIFDREHTVAKAGFNRWLVPPAALCIHLCIGMAYGFSVFWLPLSRAIGVTQSTVCTDMTLLQELFT
TSCDWKVASLGWMYTLFFVLLGGSAAVWGGWLERAGPRKAGAVAACCWGGGLLIAALGIYVHQLWMMWLGAGVIGGIGLG
LGYISPVSTLVKWFPDRRGMATGMAIMGFGGGAMIGAPLANLLMNYFKTPTSVGVWETFVTMGVIYFVFMMIGAFAYRVA
PVGWQPEGWTPPAVKKAMISEHHVHLDNAHKTPQFWLVWWVLCLNVSAGIGVIGMASPMLQEIFAGKLIGLPDVSFNQLD
ATQKATVAGIAAGFAGLLSLFNIGGRFFWASLSDHIGRKATYYCFFLIGIVLYALAPTFAAMGSKLLFVGAFAIILSMYG
GGFATVPAYLADLFGTQFVGAIHGRLLTAWATAGIIGPVVVNYIREFQLAAGVPRDQLYNTTMYILCAMLLAGLICNFMI
KPVDHKWNMSPEEVARYQAELAKSESAIQHGSFGIGKGGLDLSSALFWAFVGVPLAWGVWKTLESAVKIF

Specific function: Anion transporter that carries out the exchange of divalent oxalate with monovalent formate, the product of oxalate decarboxylation, at the plasma membrane, and in doing so catalyzes the vectorial portion of a proton-motive metabolic cycle that drives ATP

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. OFA (TC 2.A.1.11) family [H]

Homologues:

Organism=Escherichia coli, GI1789969, Length=370, Percent_Identity=25.4054054054054, Blast_Score=98, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR004741 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 59266; Mature: 59134

Theoretical pI: Translated: 8.52; Mature: 8.52

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
6.0 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHCC
>Mature Secondary Structure 
ATIESAGSLPNAQAGIFDREHTVAKAGFNRWLVPPAALCIHLCIGMAYGFSVFWLPLSR
CCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH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HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8636101; 9651403; 11919184; 11113128; 11274108; 11500368 [H]