Click here to switch to the map view.

The map label for this gene is pip [H]

Identifier: 146342633

GI number: 146342633

Start: 5998387

End: 5999376

Strand: Direct

Name: pip [H]

Synonym: BRADO5798

Alternate gene names: 146342633

Gene position: 5998387-5999376 (Clockwise)

Preceding gene: 146342632

Following gene: 146342634

Centisome position: 80.44

GC content: 69.7

Gene sequence:

>990_bases
ATGCCTGACGCCGAAGCCGGCCGCGCCGCCGCGCGCCGCAACGATCCGTTCGCGCCGCTGACGTCGGAATGGCTCGACGT
CTCCGGCGGCCACCAGATCTATGTCGAGAGCAGCGGCCGCGAGGGCGGGCGTCCCGCCGTCTATCTGCACGGCGGCCCCG
GGTCCGGCTGCCAGCCGGATCACCGCCGCCTGTTCGATCCGGAGCGCTTCCACGCCGTGCTGTTCGACCAGCGCGGCGCC
GGCCGCTCGCGCCCCTCGCGCAGCCGCGACAACAACACCCTGCCCGATCTGATCGCCGACATGGAGGCGATCCGCGCCAA
GTTCGGCTTCGAGCGCTGGATGGTCGTCGGCGGCTCCTGGGGCGCAACGCTCGCTCTGGCATATGCCGAAGCGCATCCGG
AGCGCGTGAGCGGCCTGGTTCTGCGTGCGACTTTTCTCGGCACACGCGCCGAAGTGGAGATGGCGTTCGGCGAGACGCTG
GCGCGCTTCCACCCCTCGCTCCACCGCGACTTCCTGGAGATGCTGCCGGAGAACGAGCGCGCCAATCCGTGCCAATCCTA
TTTCAAGCGCATCCTCGATCCGGATCCGGCGATCCACGGCCCGGCCGCCCGCGCCTGGCATGACACCGAGCGGGCGCTCT
CGGAGGTGAAGCCGTCGCGCACCCATCTCGACCGTCTCGCCATCCGCTCCGGCAGCGCGCTGCCGGCGACGCCGTTCATG
GAGGCGCATTACTTCTCGCACGACAGCTTCATGGCGCCCGACCAGCTGCTGCGCGGTGCGGCGAGGCTCGCCGGCATTCC
CGGCATCATCGTGCAGGGCCGCTACGACCTGCTCTGCCCGCCCCAGACCTCTGCCCGGCTCGCCGACGTCTGGCGCGACG
CCGAAATCCGTGTCGTCGAAGCCGCAGGTCACAATCTTTATGATCCCGGCATCCGCGATGCGGTCATGAAAGCCATCTGC
GATATGGCGACGCGCGCGAGCGCGCCTTAA

Upstream 100 bases:

>100_bases
CTGCACGAGAGCATCTTCAAGCAGGCCGAGCGCGATGCCGCCTCCGGTCAGGACCGCTTCCTGTATCGCAATTTTGCCGG
CGGCACGCCCGAGAGCCACG

Downstream 100 bases:

>100_bases
ACACATCACTCATTCCCCTCATGCTGAGGAGGCGCGTCAGCGCCGTCTCGAAGCATGAGGCCCGCGCCATCCGGGCCTCA
TCCTTCGAGACGGCCGCCTT

Product: proline iminopeptidase

Products: NA

Alternate protein names: PIP; Prolyl aminopeptidase; PAP [H]

Number of amino acids: Translated: 329; Mature: 328

Protein sequence:

>329_residues
MPDAEAGRAAARRNDPFAPLTSEWLDVSGGHQIYVESSGREGGRPAVYLHGGPGSGCQPDHRRLFDPERFHAVLFDQRGA
GRSRPSRSRDNNTLPDLIADMEAIRAKFGFERWMVVGGSWGATLALAYAEAHPERVSGLVLRATFLGTRAEVEMAFGETL
ARFHPSLHRDFLEMLPENERANPCQSYFKRILDPDPAIHGPAARAWHDTERALSEVKPSRTHLDRLAIRSGSALPATPFM
EAHYFSHDSFMAPDQLLRGAARLAGIPGIIVQGRYDLLCPPQTSARLADVWRDAEIRVVEAAGHNLYDPGIRDAVMKAIC
DMATRASAP

Sequences:

>Translated_329_residues
MPDAEAGRAAARRNDPFAPLTSEWLDVSGGHQIYVESSGREGGRPAVYLHGGPGSGCQPDHRRLFDPERFHAVLFDQRGA
GRSRPSRSRDNNTLPDLIADMEAIRAKFGFERWMVVGGSWGATLALAYAEAHPERVSGLVLRATFLGTRAEVEMAFGETL
ARFHPSLHRDFLEMLPENERANPCQSYFKRILDPDPAIHGPAARAWHDTERALSEVKPSRTHLDRLAIRSGSALPATPFM
EAHYFSHDSFMAPDQLLRGAARLAGIPGIIVQGRYDLLCPPQTSARLADVWRDAEIRVVEAAGHNLYDPGIRDAVMKAIC
DMATRASAP
>Mature_328_residues
PDAEAGRAAARRNDPFAPLTSEWLDVSGGHQIYVESSGREGGRPAVYLHGGPGSGCQPDHRRLFDPERFHAVLFDQRGAG
RSRPSRSRDNNTLPDLIADMEAIRAKFGFERWMVVGGSWGATLALAYAEAHPERVSGLVLRATFLGTRAEVEMAFGETLA
RFHPSLHRDFLEMLPENERANPCQSYFKRILDPDPAIHGPAARAWHDTERALSEVKPSRTHLDRLAIRSGSALPATPFME
AHYFSHDSFMAPDQLLRGAARLAGIPGIIVQGRYDLLCPPQTSARLADVWRDAEIRVVEAAGHNLYDPGIRDAVMKAICD
MATRASAP

Specific function: Specifically catalyzes the removal of N-terminal proline residues from peptides [H]

COG id: COG0596

COG function: function code R; Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S33 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073
- InterPro:   IPR005944
- InterPro:   IPR002410 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.4.11.5 [H]

Molecular weight: Translated: 36237; Mature: 36106

Theoretical pI: Translated: 7.00; Mature: 7.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDAEAGRAAARRNDPFAPLTSEWLDVSGGHQIYVESSGREGGRPAVYLHGGPGSGCQPD
CCCCCHHHHHHHCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCH
HRRLFDPERFHAVLFDQRGAGRSRPSRSRDNNTLPDLIADMEAIRAKFGFERWMVVGGSW
HHHCCCHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCC
GATLALAYAEAHPERVSGLVLRATFLGTRAEVEMAFGETLARFHPSLHRDFLEMLPENER
CHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
ANPCQSYFKRILDPDPAIHGPAARAWHDTERALSEVKPSRTHLDRLAIRSGSALPATPFM
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCH
EAHYFSHDSFMAPDQLLRGAARLAGIPGIIVQGRYDLLCPPQTSARLADVWRDAEIRVVE
HHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCEEEECCCCCHHHHHHHHCCCCEEEEE
AAGHNLYDPGIRDAVMKAICDMATRASAP
ECCCCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PDAEAGRAAARRNDPFAPLTSEWLDVSGGHQIYVESSGREGGRPAVYLHGGPGSGCQPD
CCCCHHHHHHHCCCCCCCCCHHHHCCCCCCEEEEECCCCCCCCCEEEEECCCCCCCCCH
HRRLFDPERFHAVLFDQRGAGRSRPSRSRDNNTLPDLIADMEAIRAKFGFERWMVVGGSW
HHHCCCHHHHHEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECCCC
GATLALAYAEAHPERVSGLVLRATFLGTRAEVEMAFGETLARFHPSLHRDFLEMLPENER
CHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCHHHHHHHHHHCCCCCC
ANPCQSYFKRILDPDPAIHGPAARAWHDTERALSEVKPSRTHLDRLAIRSGSALPATPFM
CCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCH
EAHYFSHDSFMAPDQLLRGAARLAGIPGIIVQGRYDLLCPPQTSARLADVWRDAEIRVVE
HHHHCCCCCCCCHHHHHHHHHHHCCCCCEEEECCEEEECCCCCHHHHHHHHCCCCEEEEE
AAGHNLYDPGIRDAVMKAICDMATRASAP
ECCCCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9348090; 11011150; 10467172 [H]