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The map label for this gene is 146342098

Identifier: 146342098

GI number: 146342098

Start: 5454563

End: 5456233

Strand: Direct

Name: 146342098

Synonym: BRADO5241

Alternate gene names: NA

Gene position: 5454563-5456233 (Clockwise)

Preceding gene: 146342094

Following gene: 146342100

Centisome position: 73.15

GC content: 67.92

Gene sequence:

>1671_bases
ATGCGCCGCTCGCCCCTGCTTCTTCTCCCGCTTCTCGGCCTGCTCTGGGCGTCTCCCAGCCTCGCTCAGTCGAAATCCCA
GCTCGGCCCGCTCTGCACCACCGAAACCACGCCGGCGGACCAGATGATCGCAGCCTGCAACAAGATCATCGCGCTGAAGG
TGTTTTCCGGGGGCCAGCTTGCCACGATTTATTTCTGGCGCGCCGTCGGCTGGAACAAGAAGGGCGACTACGCCCATGTG
ATCGCTGATACCACCGAGGCGATCCGGCTGCAGCCGTCGCAGGCGGTCTACAATCTCCGCGGCTCGGCCTATTACGACAA
GGGCGAGGACGACATCGCCATCGCCGACTTCAACGACGCACTCAAGCTGGGTCCGCCGAGCGCGACGATCTATCACAACC
GCGGCAATGCCTATCGCTCCAAGGGCGACTACGCCCACGCGCTCAGCGATTACGACGAGGCCATCAAGCAGAGCCCGCGC
GAAGCCTATAGCTGGCAGAACCGCGGCATCACCAAGGCTGCCCAGGGTGATCTCGACGGCGCCCTGATCGACATCAACGA
AGCGATCCGGTTGTCGCCATCGCTGGCCTCGGCCATGACCAACCGCTCGGTGATCTGGCGCGCCAAGGGCAATATCGAGC
GCGCCATCGCCGACGGCTCCGAGGCGGTCAGGCTGGCGCAGAACCCGCCCGCCAATGTGATGACCCCGCCCGGCAGCGTC
GTCATCGCGGCGCTGGTGCATCGCGCGCTCGCCTATGAAGCCAGGGGCGAGTTCGACGCCGCCAAGGCCGACTATGCGGC
CGCGCTGAAGCCGCTGGCATCGGATTCCGGCAGCAAAGCCAACCAGGCGACCGCCAAGGTGCGGCTGTCGCTGCTGTCGG
AGCCGGCCCCGCCGCCGCAGCAGCGCGCCGAGGCGCCGGTCTCGCCGTCATCTCCTGCTCCGGCGACGACGGGCCAACGC
ATGGCGCTCGTCATCGGCAACGGCGCCTATGCGCATGTGCAAGCCCTTCCCAATCCGCCGCGCGATGCCCGCGCGATCGC
CAAGAGCCTGCGCGACATCGGCTTCAGCGTGGTCGAAGGCATCGATCTGGATCGCGCGGCGATGCAGGCCAGGACCCGCG
ACTTCTTGCGCGAGGCCGCGCGAGCGCAGGTGGCGGTCGTGTTCTATGCCGGTCACGGCGTGCAGATCGACGGCCGCAAC
TATCTCCTCCCCACTGACATCGCATTGTCGAACGGCAGCGACGTCGTCTCCGCGATGGTCGACATGGACCAGATCCTCGC
CGGGCTCGACGACCAGGTCCGCACCAACATCCTGATCCTCGACGCCTGCCGCAACAATCCGTTCGCGCCGCCGGAAGGCT
CAGGCCCCGCGCCGAGCCGCGGCCTGAGCGCCACTGGCCTTGCGGCCCCCTCGTCGCTCGGCACCGGCGCGACGTCCGGC
GCCGGCACGCTGATCGCGTTCGCGACCGCGCCAGGCAAGGCGGCGCTCGACGGCGACGGCGAGAACAGCCCGTTCTCCGC
GGCGCTGTCGCGCCACATCGGTACGCCCGGACTCGAGGTGCAGCAGATGCTGACACGCGTGCGCGCCGAGGTCGTTGCCG
GCACCAAAAACAAGCAGGTGCCGTGGTCGAACTCCTCGCTGCTGGGCGAGGTCTATCTGGCGGCCAGATGA

Upstream 100 bases:

>100_bases
GCACCTTCTGCCCACCAATGGAAAGGGCCTGAACCCGGAACCTTCCGGGCGCAACAAACGGGATATGGTTTCCCCGCGCT
TCCCGTTCCGGTCCCTCCTT

Downstream 100 bases:

>100_bases
GTCGGAGTGCCGCGCACCGGCGCGGGCGCGTCGAGCAGGGCCGTCCACGTCAGGTCGCTTTCAACTGGACCCAGAGCGAG
TGCCCGAGGCGTTCCCGATC

Product: hypothetical protein

Products: NA

Alternate protein names: TPR Repeat-Containing Protein; Tetratricopeptide Repeat Domain Protein; Tetratricopeptide TPR_2 Repeat Protein; TPR Domain-Containing Protein; Tetratricopeptide Repeat-Containing Protein; Caspase Domain Protein; TPR Repeat-Containing Serine/Threonin Protein Kinase; O-Linked GlcNAc Transferase; Peptidase C; Caspase-Like Domain-Containing Protein; Peptidase Protein; Tetratricopeptide Tpr_1 Repeat-Containing Protein; Caspase Domain-Containing Protein; Tetratricopeptide Repeat Family Protein; TPR Domain Protein; Caspase-Like Domain- And TPR Repeat-Containing Peptidase; GUN4-Like Family; TPR Repeats Containing Protein; Caspase; TPR Repeat- And Protein Kinase Domain-Containing Protein; Pentapeptide Repeat-Containing Serine/Threonine Kinase; TPR Repeat-Containing Protein Kinase; Peptidylprolyl Isomerase; Caspase-1 P; ICE-Like Protease

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MRRSPLLLLPLLGLLWASPSLAQSKSQLGPLCTTETTPADQMIAACNKIIALKVFSGGQLATIYFWRAVGWNKKGDYAHV
IADTTEAIRLQPSQAVYNLRGSAYYDKGEDDIAIADFNDALKLGPPSATIYHNRGNAYRSKGDYAHALSDYDEAIKQSPR
EAYSWQNRGITKAAQGDLDGALIDINEAIRLSPSLASAMTNRSVIWRAKGNIERAIADGSEAVRLAQNPPANVMTPPGSV
VIAALVHRALAYEARGEFDAAKADYAAALKPLASDSGSKANQATAKVRLSLLSEPAPPPQQRAEAPVSPSSPAPATTGQR
MALVIGNGAYAHVQALPNPPRDARAIAKSLRDIGFSVVEGIDLDRAAMQARTRDFLREAARAQVAVVFYAGHGVQIDGRN
YLLPTDIALSNGSDVVSAMVDMDQILAGLDDQVRTNILILDACRNNPFAPPEGSGPAPSRGLSATGLAAPSSLGTGATSG
AGTLIAFATAPGKAALDGDGENSPFSAALSRHIGTPGLEVQQMLTRVRAEVVAGTKNKQVPWSNSSLLGEVYLAAR

Sequences:

>Translated_556_residues
MRRSPLLLLPLLGLLWASPSLAQSKSQLGPLCTTETTPADQMIAACNKIIALKVFSGGQLATIYFWRAVGWNKKGDYAHV
IADTTEAIRLQPSQAVYNLRGSAYYDKGEDDIAIADFNDALKLGPPSATIYHNRGNAYRSKGDYAHALSDYDEAIKQSPR
EAYSWQNRGITKAAQGDLDGALIDINEAIRLSPSLASAMTNRSVIWRAKGNIERAIADGSEAVRLAQNPPANVMTPPGSV
VIAALVHRALAYEARGEFDAAKADYAAALKPLASDSGSKANQATAKVRLSLLSEPAPPPQQRAEAPVSPSSPAPATTGQR
MALVIGNGAYAHVQALPNPPRDARAIAKSLRDIGFSVVEGIDLDRAAMQARTRDFLREAARAQVAVVFYAGHGVQIDGRN
YLLPTDIALSNGSDVVSAMVDMDQILAGLDDQVRTNILILDACRNNPFAPPEGSGPAPSRGLSATGLAAPSSLGTGATSG
AGTLIAFATAPGKAALDGDGENSPFSAALSRHIGTPGLEVQQMLTRVRAEVVAGTKNKQVPWSNSSLLGEVYLAAR
>Mature_556_residues
MRRSPLLLLPLLGLLWASPSLAQSKSQLGPLCTTETTPADQMIAACNKIIALKVFSGGQLATIYFWRAVGWNKKGDYAHV
IADTTEAIRLQPSQAVYNLRGSAYYDKGEDDIAIADFNDALKLGPPSATIYHNRGNAYRSKGDYAHALSDYDEAIKQSPR
EAYSWQNRGITKAAQGDLDGALIDINEAIRLSPSLASAMTNRSVIWRAKGNIERAIADGSEAVRLAQNPPANVMTPPGSV
VIAALVHRALAYEARGEFDAAKADYAAALKPLASDSGSKANQATAKVRLSLLSEPAPPPQQRAEAPVSPSSPAPATTGQR
MALVIGNGAYAHVQALPNPPRDARAIAKSLRDIGFSVVEGIDLDRAAMQARTRDFLREAARAQVAVVFYAGHGVQIDGRN
YLLPTDIALSNGSDVVSAMVDMDQILAGLDDQVRTNILILDACRNNPFAPPEGSGPAPSRGLSATGLAAPSSLGTGATSG
AGTLIAFATAPGKAALDGDGENSPFSAALSRHIGTPGLEVQQMLTRVRAEVVAGTKNKQVPWSNSSLLGEVYLAAR

Specific function: Unknown

COG id: COG4249

COG function: function code R; Uncharacterized protein containing caspase domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI32307148, Length=221, Percent_Identity=28.0542986425339, Blast_Score=72, Evalue=2e-12,
Organism=Homo sapiens, GI32307150, Length=221, Percent_Identity=28.0542986425339, Blast_Score=71, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 58577; Mature: 58577

Theoretical pI: Translated: 8.40; Mature: 8.40

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION ; PS00107 PROTEIN_KINASE_ATP ; PS50208 CASPASE_P20

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRSPLLLLPLLGLLWASPSLAQSKSQLGPLCTTETTPADQMIAACNKIIALKVFSGGQL
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCE
ATIYFWRAVGWNKKGDYAHVIADTTEAIRLQPSQAVYNLRGSAYYDKGEDDIAIADFNDA
EEEEEEEECCCCCCCCEEEEEECCCHHEEECCHHHHHCCCCCEECCCCCCCEEEEECCCC
LKLGPPSATIYHNRGNAYRSKGDYAHALSDYDEAIKQSPREAYSWQNRGITKAAQGDLDG
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHCCCCCC
ALIDINEAIRLSPSLASAMTNRSVIWRAKGNIERAIADGSEAVRLAQNPPANVMTPPGSV
EEEECCHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHCCCHHEEECCCCCCCCCCCCHHH
VIAALVHRALAYEARGEFDAAKADYAAALKPLASDSGSKANQATAKVRLSLLSEPAPPPQ
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCH
QRAEAPVSPSSPAPATTGQRMALVIGNGAYAHVQALPNPPRDARAIAKSLRDIGFSVVEG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHC
IDLDRAAMQARTRDFLREAARAQVAVVFYAGHGVQIDGRNYLLPTDIALSNGSDVVSAMV
CCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEECCCCEECCCCEEECCCHHHHHHHH
DMDQILAGLDDQVRTNILILDACRNNPFAPPEGSGPAPSRGLSATGLAAPSSLGTGATSG
HHHHHHHCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGTLIAFATAPGKAALDGDGENSPFSAALSRHIGTPGLEVQQMLTRVRAEVVAGTKNKQV
CCEEEEEEECCCCEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PWSNSSLLGEVYLAAR
CCCCCCCEEEEEEECC
>Mature Secondary Structure
MRRSPLLLLPLLGLLWASPSLAQSKSQLGPLCTTETTPADQMIAACNKIIALKVFSGGQL
CCCCCCHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHCCEEEEEEECCCCE
ATIYFWRAVGWNKKGDYAHVIADTTEAIRLQPSQAVYNLRGSAYYDKGEDDIAIADFNDA
EEEEEEEECCCCCCCCEEEEEECCCHHEEECCHHHHHCCCCCEECCCCCCCEEEEECCCC
LKLGPPSATIYHNRGNAYRSKGDYAHALSDYDEAIKQSPREAYSWQNRGITKAAQGDLDG
CCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHCCCCCHHHCCCCCC
ALIDINEAIRLSPSLASAMTNRSVIWRAKGNIERAIADGSEAVRLAQNPPANVMTPPGSV
EEEECCHHHCCCHHHHHHHCCCEEEEEECCCCHHHHHCCCHHEEECCCCCCCCCCCCHHH
VIAALVHRALAYEARGEFDAAKADYAAALKPLASDSGSKANQATAKVRLSLLSEPAPPPQ
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCH
QRAEAPVSPSSPAPATTGQRMALVIGNGAYAHVQALPNPPRDARAIAKSLRDIGFSVVEG
HHCCCCCCCCCCCCCCCCCEEEEEEECCCEEEEEECCCCCHHHHHHHHHHHHCCHHHHHC
IDLDRAAMQARTRDFLREAARAQVAVVFYAGHGVQIDGRNYLLPTDIALSNGSDVVSAMV
CCHHHHHHHHHHHHHHHHHHHCEEEEEEEECCCEEECCCCEECCCCEEECCCHHHHHHHH
DMDQILAGLDDQVRTNILILDACRNNPFAPPEGSGPAPSRGLSATGLAAPSSLGTGATSG
HHHHHHHCCCHHHHCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
AGTLIAFATAPGKAALDGDGENSPFSAALSRHIGTPGLEVQQMLTRVRAEVVAGTKNKQV
CCEEEEEEECCCCEEECCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCC
PWSNSSLLGEVYLAAR
CCCCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA